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Family Practice Notebook Updates 2016

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41. Prophylaxis of Magnesium-rich Mineral Water to Prevent Hypomagnesemia Induced by an Anti-EGFR (OPTIMAG)

: NCT03146338 Recruitment Status : Recruiting First Posted : May 9, 2017 Last Update Posted : September 20, 2017 See Sponsor: Weprom Collaborator: Neptune Information provided by (Responsible Party): Weprom Study Details Study Description Go to Brief Summary: Anti-EGFR (Epidermal Growth Factor Receptor) therapies, namely cetuximab and panitumumab, have become standards in the management of metastatic colorectal and head and neck cancers. These therapies are used in daily practice, that requiring to manage (...) Phase Metastatic Colorectal Cancer Metastatic Head and Neck Cancer Other: Magnesium-rich mineral water (Rozana) Not Applicable Detailed Description: Anti-EGFR (Epidermal Growth Factor Receptor) therapies, namely cetuximab and panitumumab, have become standards in the management of metastatic colorectal and head and neck cancers. These therapies are used in daily practice, that requiring to manage their skin and digestive toxicities. However, anti-EGFR are also frequently responsible

2017 Clinical Trials

42. Acute Flaccid Myelitis

/2019 and last published on 3/3/2019 . Contact 2019 Family Practice Notebook, LLC. | | | | (...) Myelitis Aka: Acute Flaccid Myelitis From Related Chapters II. Epidemiology First reported in California, 2012 Outbreaks have occured in late summer and early fall (2014, 2016, 2018) Median age: 9 years old (some patients have been over age 21 years old) III. Pathophysiology Gray matter destruction typically related to viral infection IV. Symptoms Viral prodrome Meningeal symptoms may occur Neck stiffness Myalgias Preserved mental status (no encephalopathy in most cases) Rapidly progressive

2019 FP Notebook

43. Management of Thyroid Cancer

cen_frontmatter.indd ii 6/27/2014 3:52:19 PM 6/27/2014 3:52:19 PMiii l o . n - y d - s e Thyroid Cancer Guidelines Update Group v Notes on the development and use of the guidelines vii Types of evidence and grading of recommendations viii Abbreviations ix Key recommendations and overview of management of thyroid cancer 1. Access to a multidisciplinary thyroid cancer team x 2. Patient focus x 3. Prognostic factors, staging, risk strati? cation and management of uncertainty in differentiated thyroid cancer x 4 (...) ), Professor of Endocrinology, Imperial College Lon- don (British Thyroid Association representative). Thyroid Cancer Guidelines Update Group Association of Clinical Biochemistry British Association of Endocrine and Thyroid Surgeons British Association of Head and Neck Oncologists British Association of Otolaryngologists/Head and Neck Surgeons of ENT UK British Association for Cytopathology British Association of Surgical Oncology British Nuclear Medicine Society British Thyroid Association British Society

2014 British Association of Endocrine and Thyroid Surgeons

44. Multidisciplinary Postacute Rehabilitation for Moderate to Severe Traumatic Brain Injury in Adults

Road Rockville, MD 20850 www.ahrq.gov Contract No. 290-2007-10064-I Prepared by: Minnesota Evidence-based Practice Center Minneapolis, MN Investigators: Michelle Brasure, Ph.D., M.L.I.S. Greg J. Lamberty, Ph.D., L.P., ABPP Nina A. Sayer, Ph.D. Nathaniel W. Nelson, Ph.D., ABPP Roderick MacDonald, M.S. Jeannine Ouellette, M.S. James Tacklind, B.S. Michael Grove, M.S. Indulis R. Rutks, B.S. Mary E. Butler, Ph.D., M.B.A. Robert L. Kane, M.D. Timothy J. Wilt, M.D., M.P.H. AHRQ Publication No. 12-EHC101 (...) -EF June 2012 ii This report is based on research conducted by the Minnesota Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 290-2007-10064-I). The findings and conclusions in this document are those of the authors, who are responsible for its contents; the findings and conclusions do not necessarily represent the views of AHRQ. Therefore, no statement in this report should be construed as an official

2012 Effective Health Care Program (AHRQ)

45. Validation of the Questionnaire ASES

of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02977325 Recruitment Status : Completed First Posted : November 30, 2016 Last Update Posted : December 5, 2016 Sponsor: University Hospital, Clermont-Ferrand Collaborators: Clermont Communauté Innovatherm Information provided by (Responsible Party): University Hospital, Clermont-Ferrand Study (...) Responsible Party: University Hospital, Clermont-Ferrand ClinicalTrials.gov Identifier: Other Study ID Numbers: CHU-0293 First Posted: November 30, 2016 Last Update Posted: December 5, 2016 Last Verified: December 2016 Keywords provided by University Hospital, Clermont-Ferrand: Physical activity level Personal efficacy Knee osteoarthritis Self-management Self-care Education and exercise in knee osteoarthritis Additional relevant MeSH terms: Layout table for MeSH terms Osteoarthritis Osteoarthritis, Knee

2016 Clinical Trials

46. Game-Based Rehabilitation Platform for Children With Neurodevelopmental Disorders and Acquired Brain Injuries

of Manitoba. Recruitment status was: Not yet recruiting First Posted : April 5, 2016 Last Update Posted : April 5, 2016 Sponsor: University of Manitoba Collaborators: S.D.M. College of Physiotherapy, Dharwad, India Christian Medical College and Hospital, Ludhiana, India Information provided by (Responsible Party): University of Manitoba Study Details Study Description Go to Brief Summary: This research project focuses on the evaluation of an engaging exercise and cognitive computer game-based platform (...) Szturm, Ph.D. Associate Professor More Information Go to Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number): Layout table for additonal information Responsible Party: University of Manitoba ClinicalTrials.gov Identifier: Other Study ID Numbers: H2016:061 First Posted: April 5, 2016 Last Update Posted: April 5, 2016 Last Verified: March 2016 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Additional relevant MeSH terms

2016 Clinical Trials

47. Video » Webinar: Severe Irritability and DMDD in Youth -- Dr. Kenneth Towbin

boy who is in his early high school years is usually quite shy and very rule abiding, but during one week he has this period where his sleep declines quite significantly. He's only sleeping 4-5 hours a night instead of 8 or 8 1/2 hours which is typical for him. He has strange ideas and has this notion that he's writing three novels at once and with this time that he's not sleeping, he's up writing and writing and writing in notebooks and journals his ideas for these three novels that his composing (...) they have a similar longitudinal course, whether their family histories would be similar. Because of course if they are similar conditions then the kinds of diagnosis and their families should be much the same and then of course the coin of the realm would be to look at the path of pathophysiology to look at brain functioning to see whether there were similarities in brain functioning. And I want to remind all of you that the criteria that we came up with were really created to answer this specific

2016 NIMH blog

48. Pyrazinamide

2019 Family Practice Notebook, LLC. | | | | (...) . Related Studies (from Trip Database) Cost: Medications pyrazinamide (on 11/30/2016 at ) PYRAZINAMIDE 500 MG TABLET Generic $2.59 each FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See for financial assistance information

2018 FP Notebook

49. Leukotriene Receptor Antagonist

chapters. Content is with systematic literature reviews and conferences. Although access to this website is not restricted, the information found here is intended for use by medical providers. Patients should address specific medical concerns with their physicians. This page was written by , last revised on 2/10/2018 and last published on 3/2/2019 . Contact 2019 Family Practice Notebook, LLC. | | | | (...) ZAFIRLUKAST 20 MG TABLET Generic $1.30 each montelukast (on 5/17/2017 at ) MONTELUKAST SOD 10 MG TABLET Generic $0.10 each MONTELUKAST SOD 4 MG GRANULES Generic $3.25 each MONTELUKAST SOD 4 MG TAB CHEW Generic $0.18 each MONTELUKAST SOD 5 MG TAB CHEW Generic $0.17 each singulair (on 6/8/2017 at ) SINGULAIR 10 MG TABLET Generic $0.10 each SINGULAIR 4 MG GRANULES Generic $3.25 each SINGULAIR 4 MG TABLET CHEW Generic $0.18 each SINGULAIR 5 MG TABLET CHEW Generic $0.17 each zyflo (on 12/1/2016 at ) ZYFLO CR

2018 FP Notebook

50. Short-acting Beta Agonist

. Content is with systematic literature reviews and conferences. Although access to this website is not restricted, the information found here is intended for use by medical providers. Patients should address specific medical concerns with their physicians. This page was written by , last revised on 11/5/2018 and last published on 3/2/2019 . Contact 2019 Family Practice Notebook, LLC. | | | | (...) : 2 puffs q4-6 hours Not as potently dosed as others Use for patients sensitive to adrenergic effects Pirbuterol (Maxair) Maxair Autohaler will be only CFC on U.S. market Cost: $19.53 per 30 days Dose: 2 puffs q4-6 hours Albuterol (Ventolin, Proventil, ProAir HFA, ProAir RespiClick) Preparations ProAir HFA s Replaced CFC s ric as of December 2016 ProAir RespiClick ( , released 2015) Requires deep inhalation, but no spacer needed Approved age 12 years and older Cost Expensive ($50/ ) - no generic

2018 FP Notebook

51. Long-acting Anticholinergic Bronchodilator

with their physicians. This page was written by , last revised on 6/2/2018 and last published on 3/2/2019 . Contact 2019 Family Practice Notebook, LLC. | | | | (...) adverse effects or other Paradoxical bronchospasm exacerbation Initial report suggests risk as high as 2 cases per 1000 patients per year Confirmatory studies required and patients may continue on Spiriva currently (2008) Prescriber's Letter 15(4):21 Common adverse effects effects (e.g. blurred vision, , , ) Gastrointestinal upset (e.g. , ) or XI. References (2016) Presc Lett 23(2): 10 (2015) Presc Lett 22(1): 4-5 (2012) Presc Lett 19(12): 70 Images: Related links to external sites (from Bing

2018 FP Notebook

52. Pneumonia Management in Children

with their physicians. This page was written by , last revised on 8/30/2016 and last published on 3/2/2019 . Contact 2019 Family Practice Notebook, LLC. | | | |

2018 FP Notebook

53. Pneumonia in Children

interlinked topic pages divided into a tree of 31 specialty books and 728 chapters. Content is with systematic literature reviews and conferences. Although access to this website is not restricted, the information found here is intended for use by medical providers. Patients should address specific medical concerns with their physicians. This page was written by , last revised on 8/30/2016 and last published on 3/2/2019 . Contact 2019 Family Practice Notebook, LLC. | | | |

2018 FP Notebook

54. Respiratory Syncytial Virus

. Started in 1995, this collection now contains 6656 interlinked topic pages divided into a tree of 31 specialty books and 728 chapters. Content is with systematic literature reviews and conferences. Although access to this website is not restricted, the information found here is intended for use by medical providers. Patients should address specific medical concerns with their physicians. This page was written by , last revised on 1/1/2018 and last published on 3/2/2019 . Contact 2019 Family Practice (...) Severe may result III. Risk Factors: More Severe Course Prematurity Complex Chronic lung disease Immunosuppression Neuromuscular disease Metabolic disorder IV. Pathophysiology: RSV Enveloped, nonsegmented, negative-strand RNA virus (Paramyxoviridae Family) Subtypes A (causes more severe disease) Subtypes B Transmission Close contact Fingers or fomites Self inoculation of or anterior nares Coarse aerosols from coughing or sneezing Viral load peaks at 4 to 5 days Corresponds to peak illness severity

2018 FP Notebook

55. Pulmonary Embolism in Pregnancy

/2016 and last published on 3/2/2019 . Contact 2019 Family Practice Notebook, LLC. | | | | (...) in life-threatening massive if not near term X. Prevention See for prophylaxis XI. References Swaminathan and Kline in Herbert (2016) EM:Rap 16(3): 1-3 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Pulmonary Embolism in Pregnancy." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Obstetrics About FPnotebook.com is a rapid access, point

2018 FP Notebook

56. Pulmonary Function Test

. This page was written by , last revised on 9/16/2016 and last published on 3/2/2019 . Contact 2019 Family Practice Notebook, LLC. | | | |

2018 FP Notebook

57. Oxygen Saturation

providers. Patients should address specific medical concerns with their physicians. This page was written by , last revised on 4/26/2018 and last published on 3/2/2019 . Contact 2019 Family Practice Notebook, LLC. | | | | (...) to tissue (Same O2 Sat implies lower ) Increased pH Decreased Decreased Decreased 2,3-dpg Right Shift from physiologic stress (Same O2 Sat implies higher , lower O2 affinity, greater O2 tissue delivery) Increased Increased Increased 2,3-dpg Decreased pH IX. References Killu and Sarani (2016) Fundamental Critical Care Support, p. 93-114 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Oxygen Saturation." Click on the image (or right

2018 FP Notebook

58. Headache Red Flag

, the information found here is intended for use by medical providers. Patients should address specific medical concerns with their physicians. This page was written by , last revised on 2/9/2016 and last published on 3/3/2019 . Contact 2019 Family Practice Notebook, LLC. | | | |

2018 FP Notebook

59. Cerebral Spinal Fluid

chapters. Content is with systematic literature reviews and conferences. Although access to this website is not restricted, the information found here is intended for use by medical providers. Patients should address specific medical concerns with their physicians. This page was written by , last revised on 3/4/2016 and last published on 3/3/2019 . Contact 2019 Family Practice Notebook, LLC. | | | |

2018 FP Notebook

60. Confusion Assessment Method

2019 Family Practice Notebook, LLC. | | | | (...) and emergency clinicians. Started in 1995, this collection now contains 6656 interlinked topic pages divided into a tree of 31 specialty books and 728 chapters. Content is with systematic literature reviews and conferences. Although access to this website is not restricted, the information found here is intended for use by medical providers. Patients should address specific medical concerns with their physicians. This page was written by , last revised on 10/2/2016 and last published on 3/3/2019 . Contact

2018 FP Notebook

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