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Family Practice Notebook Updates 2016

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2581. brachial neuritis

brachial neuritis brachial neuritis - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search brachial neuritis Neuralgic amyotrophy is a relatively common disorder characterised by the acute onset of shoulder pain and weakness. Often, the pathology or site of the lesion is not known. It is most frequent in young males. It is to be distinguished from familial brachial neuritis which is associated with abnormalities of peripheral (...) nerves - thickened myelin sheaths. Reference: Lindsay, 'Neurology and Neurosurgery', 2010, Churchill Livingstone Bannister, 'Brain and Bannister's Clinical Neurology', (1992 - reprinted 2004), OMP. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge

2010 GP Notebook

2582. multiple endocrine neoplasia type II

multiple endocrine neoplasia type II multiple endocrine neoplasia type II - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search multiple endocrine neoplasia type II In the UK, about 20 cases per year of this form of MEN are diagnosed. MEN type II is a familial predisposition to tumours of the thyroid parafollicular C cells and the adrenal medulla. There are two variants: MEN-2A MEN-2B The condition has been mapped to chromosome (...) 10q11.2. The standard screening test for MEN-II is the measurement of serum calcitonin after the administration of pentagastrin. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information

2010 GP Notebook

2583. combined contraceptive pill and breast cancer

. BMJ 1996; 313: 63-4 MeReC Bulletin (2006); 17(2):1-9. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives (...) combined contraceptive pill and breast cancer combined contraceptive pill and breast cancer - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search combined contraceptive pill and breast cancer There is evidence (1,2) that women who currently use or have stopped using combined oral contraceptive pills have a slightly increased risk of breast cancer (odds ratio 1.24 for current users and 1.16 for women who stopped using the pill

2010 GP Notebook

2584. grief

provided by family and friends. The professional person who is involved should be able to assess whether the grief is proceeding as expected and whether the bereaved person is receiving the help which he needs from others. In addition, the professional should be able to recognise complications, know how and when to intervene, and when to seek more expert help in management. In order to do these things it is important to be familiar with normal and abnormal grief. Links: General Practice Notebook (...) General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data

2010 GP Notebook

2585. diagnosis and assessment of chronic heart failure (CHF) in primary care

dysfunction [eGFR less than 60 ml/minute/1.73m2], sepsis, chronic obstructive pulmonary disease, diabetes, or cirrhosis of the liver) Reference: (2) Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication (...) diagnosis and assessment of chronic heart failure (CHF) in primary care diagnosis and assessment of chronic heart failure (CHF) in primary care - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search diagnosis and assessment of chronic heart failure (CHF) in primary care the NICE clinical guideline on CHF the use of BNP as a diagnostic tool for heart failure (1,2) refer patients with suspected heart failure and previous

2010 GP Notebook

2586. spirometry in diagnosis of COPD

spirometry in diagnosis of COPD spirometry in diagnosis of COPD - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search spirometry in diagnosis of COPD Think of diagnosis of COPD in patients who are (1,2): over 35 and smokers or ex-smokers and have any of these symptoms: exertional breathlessness chronic cough regular sputum production frequent winter ’bronchitis’ wheeze and have no clinical features of asthma , for example (...) (2004) Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. European Respiratory Journal 23(6): 932-46. Global Initiative for Chronic Obstructive Lung Disease (GOLD) (2008) Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease Reference: (1) (2) (3) Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical

2010 GP Notebook

2587. arterial leg ulcer

arterial leg ulcer arterial leg ulcer - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search arterial leg ulcer Arterial ulceration is caused by reduced blood supply to the lower limb. it is the second most common ulcer in the lower extremity and accounts for about 10% all leg ulcers both sexes are equally affected (1) Arterial or arteriolar obstruction leads to ischemia of the skin and subcutaneous tissues which may result (...) or macrovascular disease, vasculitis, pyoderma gangrenosum, thalassaemia, and sickle cell disease (1,2) Reference: (1) (2) Agale SV. Chronic Leg Ulcers: Epidemiology, Aetiopathogenesis, and Management. Ulcers 2013;vol. 2013, Article ID 413604, 9 pages (3) Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all

2010 GP Notebook

2588. fingerprinting (DNA)

. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence (...) fingerprinting (DNA) fingerprinting (DNA) - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search fingerprinting (DNA) This technique involves the use of restriction fragment length polymorphisms (RFLP): fragments of DNA of differing molecular mass between individuals resulting from digestion of the genome by restriction enzymes. This DNA may be isolated from a forensic specimen and from the blood of a suspect. A specific

2010 GP Notebook

2589. diagnosis of heart failure (left ventricular dysfunction) in primary care

dysfunction [eGFR less than 60 ml/minute/1.73m2], sepsis, chronic obstructive pulmonary disease, diabetes, or cirrhosis of the liver) Reference: (2) Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication (...) diagnosis of heart failure (left ventricular dysfunction) in primary care diagnosis of heart failure (left ventricular dysfunction) in primary care - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search diagnosis of heart failure (left ventricular dysfunction) in primary care the NICE clinical guideline on CHF the use of BNP as a diagnostic tool for heart failure (1,2) refer patients with suspected heart failure and previous

2010 GP Notebook

2590. hereditary spastic paraplegia

: evaluation of locus heterogeneity, anticipation, and haplotype mapping of the SPG4 locus on the short arm of chromosome 2. American Journal of Medical Genetics 1997;74(1):26-36. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any (...) hereditary spastic paraplegia hereditary spastic paraplegia - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search hereditary spastic paraplegia This is a hereditary neurodegenerative disorder which in its simple form results in a progressive spastic paraplegia. Patients present at any time from childhood to old age. There are two main forms of the disease: early onset with a very indolent course later onset, 40-60 yrs

2010 GP Notebook

2591. DNA fingerprinting

. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence (...) DNA fingerprinting DNA fingerprinting - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search DNA fingerprinting This technique involves the use of restriction fragment length polymorphisms (RFLP): fragments of DNA of differing molecular mass between individuals resulting from digestion of the genome by restriction enzymes. This DNA may be isolated from a forensic specimen and from the blood of a suspect. A specific restriction

2010 GP Notebook

2592. cystic disease of biliary tract

cystic disease of biliary tract cystic disease of biliary tract - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search cystic disease of biliary tract Caroli's disease is a rare congenital, non familial condition characterised by multiple, irregular, saccular dilatations of the intrahepatic ducts separated by segments of normal or stenotic ducts. Links: General Practice Notebook General Practice Notebook The information provided (...) herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your computer called cookies so that we can

2010 GP Notebook

2593. apo C-II deficiency

, causing an accumulation of chylomicrons and very low density lipoproteins (VLDL) xanthomas and hepatosplenomegaly are less common in C-II anapolipoproteinemia than in lipoprotein lipase deficiency (1) Reference: Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 (...) apo C-II deficiency apo C-II deficiency - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search apo C-II deficiency Lipoprotein lipase deficiency is a rare condition and inherited as an autosomal recessive condition. It is characterised by the presence of chylomicrons in fasting plasma. Fasting tryglyceride levels are characteristically > 10 mmol/L. Characteristically there is a fasting hypertriglyceridaemia and chylomicronaemia

2010 GP Notebook

2594. carcinoma (thyroid)

carcinoma (thyroid) carcinoma (thyroid) - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search carcinoma (thyroid) Thyroid carcinoma is rare, having an annual incidence of about 3-5 per 100,000. thyroid cancer accounts for about 0.4% of all cancer deaths. women are affected more commonly than men in a ratio of 2-3:1 most likely to develop in women of reproductive age usually presents as a solitary nodule in a patient with normal (...) with radioiodine there are two rare types which occur in the elderly about 1% of patients have lymphoma of the thyroid, which presents as a rapidly expanding mass and is usually diagnosed on the basis of the patient’s history, together with a tissue diagnosis many of these patients can be cured 3% of patients who have anaplastic thyroid cancer, which presents in a similar way and must be differentiated from lymphoma with a biopsy prognosis is poor Reference: Links: General Practice Notebook General Practice

2010 GP Notebook

2595. infantile spasms

infantile spasms infantile spasms - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search infantile spasms Infantile spasm (IS), also known as West syndrome, is a unique form of epilepsy present almost entirely during infancy (the first year of life) (1). IS was first described in 1841 by Dr. William James West in a letter to Lancet , describing new infantile convulsions in his 4-month-old son (2). The condition is characterised (...) category early effective treatment will result in improved prognosis symptomatic form underlying structural, metabolic or genetic cause can be identified developmental delay is seen prior to the onset of spasms idiopathic normal development prior to onset of spasms no residual dysfunction normal neuroimaging and normal etiologic evaluation, and normal neurodevelopment. Reference: (1) (2) (3) (4) Links: General Practice Notebook General Practice Notebook The information provided herein should

2010 GP Notebook

2596. cot death

when more than one child in a family has died. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from (...) cot death cot death - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search cot death Sudden infant death syndrome is the commonest cause of death in the first year of life, causing one to two deaths per thousand livebirths. The incidence of sudden infant death has fallen in the past decade, and is currently steady at around 3 per 1000 live births commonest at 3 months more common in Winter and cities Sweden has a 1/4 the rate

2010 GP Notebook

2597. SUDS

than one child in a family has died. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from (...) SUDS SUDS - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search SUDS Sudden infant death syndrome is the commonest cause of death in the first year of life, causing one to two deaths per thousand livebirths. The incidence of sudden infant death has fallen in the past decade, and is currently steady at around 3 per 1000 live births commonest at 3 months more common in Winter and cities Sweden has a 1/4 the rate of the UK

2010 GP Notebook

2598. chylomicronaemia syndrome

chylomicronaemia syndrome chylomicronaemia syndrome - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search chylomicronaemia syndrome Lipoprotein lipase deficiency is a rare condition and inherited as an autosomal recessive condition. It is characterised by the presence of chylomicrons in fasting plasma. Fasting tryglyceride levels are characteristically > 10 mmol/L. Characteristically there is a fasting hypertriglyceridaemia (...) of apolipoprotein C-II, causing an accumulation of chylomicrons and very low density lipoproteins (VLDL) xanthomas and hepatosplenomegaly are less common in C-II anapolipoproteinemia than in lipoprotein lipase deficiency (1) Reference: Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions

2010 GP Notebook

2599. thyroid adenocarcinomas

thyroid adenocarcinomas thyroid adenocarcinomas - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search thyroid adenocarcinomas Thyroid carcinoma is rare, having an annual incidence of about 3-5 per 100,000. thyroid cancer accounts for about 0.4% of all cancer deaths. women are affected more commonly than men in a ratio of 2-3:1 most likely to develop in women of reproductive age usually presents as a solitary nodule in a patient (...) with radioiodine there are two rare types which occur in the elderly about 1% of patients have lymphoma of the thyroid, which presents as a rapidly expanding mass and is usually diagnosed on the basis of the patient’s history, together with a tissue diagnosis many of these patients can be cured 3% of patients who have anaplastic thyroid cancer, which presents in a similar way and must be differentiated from lymphoma with a biopsy prognosis is poor Reference: Links: General Practice Notebook General Practice

2010 GP Notebook

2600. West's syndrome

West's syndrome West's syndrome - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search West's syndrome Infantile spasm (IS), also known as West syndrome, is a unique form of epilepsy present almost entirely during infancy (the first year of life) (1). IS was first described in 1841 by Dr. William James West in a letter to Lancet , describing new infantile convulsions in his 4-month-old son (2). The condition is characterised (...) category early effective treatment will result in improved prognosis symptomatic form underlying structural, metabolic or genetic cause can be identified developmental delay is seen prior to the onset of spasms idiopathic normal development prior to onset of spasms no residual dysfunction normal neuroimaging and normal etiologic evaluation, and normal neurodevelopment. Reference: (1) (2) (3) (4) Links: General Practice Notebook General Practice Notebook The information provided herein should

2010 GP Notebook

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