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Family Practice Notebook Updates 2016

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2481. CJD

CJD CJD - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search CJD Creutzfeldt-Jacob disease (CJD) is the name given to the most common group of human prion diseases. The component diseases are: sporadic CJD iatrogenic CJD familial CJD new variant CJD Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed (...) medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your computer called cookies so that we can recognise you and provide you with the best service. If you do not want to receive cookies

2010 GP Notebook

2482. Creutzfeldt-Jacob disease

Creutzfeldt-Jacob disease Creutzfeldt-Jacob disease - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search Creutzfeldt-Jacob disease Creutzfeldt-Jacob disease (CJD) is the name given to the most common group of human prion diseases. The component diseases are: sporadic CJD iatrogenic CJD familial CJD new variant CJD Links: General Practice Notebook General Practice Notebook The information provided herein should not be used (...) for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your computer called cookies so that we can recognise you and provide you

2010 GP Notebook

2483. trypanosomiasis (American)

Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small (...) trypanosomiasis (American) trypanosomiasis (American) - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search trypanosomiasis (American) Chagas' disease is caused by Trypanosoma cruzi, which is spread by Reduviid bugs. American Trypanosomiasis or Chagas disease is an endemic disease mainly in Central and South America it is a zoonosis caused by the flagellated protozoan Trypanosoma cruzi (T. cruzi). In endemic areas, the primary

2010 GP Notebook

2484. mesothelioma

: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence (...) mesothelioma mesothelioma - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search mesothelioma a mesothelioma is associated with exposure to asbestos, especially blue asbestos. A mesothelioma is a tumour of mesothelial cells which generally occurs in the pleura (rarely a mesothelioma may occur in the peritoneum or other organs) exposure may only be brief. There may be a lag-time of 20 to 40 years. Only approximately 20

2010 GP Notebook

2485. infantile autism

infantile autism infantile autism - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search infantile autism Autism is characterized by impaired reciprocal social interaction and communication, as well as stereotyped behaviour and interests, with an onset typically before 3 years of age (1) a broader range of phenotypes is also recognized, termed autism spectrum disorders (ASDs), which include 'strict' autism, atypical autism (...) in approximately 50% of young people with autism (4) Autism was once thought to be an uncommon developmental disorder, but recent studies have reported increased prevalence and the condition is now thought to occur in at least 1% of children. This rising prevalence has increased demand for diagnostic services for children and young people of all ages in the health service. Reference: 1) 2) 3) 4) Links: General Practice Notebook General Practice Notebook The information provided herein should not be used

2010 GP Notebook

2486. post traumatic stress disorder

post traumatic stress disorder post traumatic stress disorder - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search post traumatic stress disorder Post-traumatic stress disorder (PTSD) is a reaction which a person may develop in response to one or more traumatic events/stressors. a stressor which precipitates a PTSD is often of such a magnitude that the patient's coping strategies and defense mechanisms are overwhelmed post (...) talking about their problems even when presenting with associated complaints children, particularly those aged under 8 years, may not complain directly of PTSD symptoms such as re-experiencing or avoidance instead, symptoms may take the form of re-enacting the experience, repetitive play or frightening dreams with no recognisable content Reference: (1) (2) (3) Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any

2010 GP Notebook

2487. Christmas disease

Christmas disease Christmas disease - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search Christmas disease Haemophilia B results from a congenital deficiency of Factor IX coagulant activity. It is an X-linked recessive disorder affecting 1 in 30 000 males. It 'breeds' true so that family members tend to be all severely affected or all mildly affected. It is clinically indistinguishable from haemophilia A, presenting (...) with recurrent haemorrhage, spontaneously or post-operatively, into soft tissues and joints. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge

2010 GP Notebook

2488. factor IX deficiency

factor IX deficiency factor IX deficiency - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search factor IX deficiency Haemophilia B results from a congenital deficiency of Factor IX coagulant activity. It is an X-linked recessive disorder affecting 1 in 30 000 males. It 'breeds' true so that family members tend to be all severely affected or all mildly affected. It is clinically indistinguishable from haemophilia A, presenting (...) with recurrent haemorrhage, spontaneously or post-operatively, into soft tissues and joints. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge

2010 GP Notebook

2489. BRCA genes

Reference: Pulse (2005); 65(14):55-60. Evans DGR et al. (1994). Familial breast cancer. BMJ; 308:183-7 McPherson et al. (1994). BMJ;309: 1004 Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication (...) BRCA genes BRCA genes - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search BRCA genes Up to 10% of breast cancer in western countries is due to genetic predisposition. Susceptibility to breast cancer appears to be inherited as an autosomal dominant with limited penetrance and may thus be inherited from either father or mother. About 5% of breast cancer is due to highly penetrant dominant genes. More than five genes are thought

2010 GP Notebook

2490. target cholesterol levels - primary prevention in reducing CV risk

disease [glomerular filtration rate (GFR) <60 mL/min/1.73 m2] positive family history of premature CVD. HDL and triglycerides (2) although low HDL cholesterol is an independent risk factor for CVD, no specific treatment goals are as yet defined, but may be considered at concentrations >1.0 mmol/L (40 mg/dL) in men and >1.2 mmol/ 45 mg/dL) in women. Similarly, fasting triglycerides should be <.1.7 mmol/L (150 mg/dL). Reference: Links: General Practice Notebook General Practice Notebook The information (...) target cholesterol levels - primary prevention in reducing CV risk target cholesterol levels - primary prevention in reducing CV risk - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search target cholesterol levels - primary prevention in reducing CV risk use the QRISK2 risk assessment tool to assess CVD risk for the primary prevention of CVD in people up to and including age 84 years do not use a risk assessment tool to assess

2010 GP Notebook

2491. target cholesterol levels - primary prevention of cardiovascular (CV) disease

with moderate to severe chronic kidney disease [glomerular filtration rate (GFR) <60 mL/min/1.73 m2] positive family history of premature CVD. HDL and triglycerides (2) although low HDL cholesterol is an independent risk factor for CVD, no specific treatment goals are as yet defined, but may be considered at concentrations >1.0 mmol/L (40 mg/dL) in men and >1.2 mmol/ 45 mg/dL) in women. Similarly, fasting triglycerides should be <.1.7 mmol/L (150 mg/dL). Reference: Links: General Practice Notebook General (...) Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your

2010 GP Notebook

2492. target lipid levels - primary prevention of cardiovascular disease (CVD)

to severe chronic kidney disease [glomerular filtration rate (GFR) <60 mL/min/1.73 m2] positive family history of premature CVD. HDL and triglycerides (2) although low HDL cholesterol is an independent risk factor for CVD, no specific treatment goals are as yet defined, but may be considered at concentrations >1.0 mmol/L (40 mg/dL) in men and >1.2 mmol/ 45 mg/dL) in women. Similarly, fasting triglycerides should be <.1.7 mmol/L (150 mg/dL). Reference: Links: General Practice Notebook General Practice (...) target lipid levels - primary prevention of cardiovascular disease (CVD) target lipid levels - primary prevention of cardiovascular disease (CVD) - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search target lipid levels - primary prevention of cardiovascular disease (CVD) use the QRISK2 risk assessment tool to assess CVD risk for the primary prevention of CVD in people up to and including age 84 years do not use a risk

2010 GP Notebook

2493. BCG vaccine

: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence (...) BCG vaccine BCG vaccine - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search BCG vaccine The BCG vaccine is a live attenuated strain of mycobacterium tuberculosis which confers a useful degree of immunity in some individuals. It is given via intradermal injection (1). about 4 weeks after the injection a local skin reaction is produced and there may be regional lymphadenopathy in individuals who have developed an immune

2010 GP Notebook

2494. language delay

language delay language delay - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search language delay speech (1) is a motor act of communication through articulation of verbal expression (2) is the sound that originates in the mouth it should be differentiated from language language (1) is the knowledge of a symbol system used for communication between persons (2) is associated with meanings, rather than sounds is a measure (...) . For example the parents of a 2 year-old boy with obviously normal development but a vocabulary of only 10 to 20 words may be comparing him with the little girl of similar age in the same street but with a vocabulary of 200 words. Both are within the normal range. Reference: (1) (2) Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted

2010 GP Notebook

2495. Bacillus Calmette-Guerin vaccine

/CMO/2005/3, PL/CNO/2005/3, PL/CPHO/2005/3. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from (...) Bacillus Calmette-Guerin vaccine Bacillus Calmette-Guerin vaccine - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search Bacillus Calmette-Guerin vaccine The BCG vaccine is a live attenuated strain of mycobacterium tuberculosis which confers a useful degree of immunity in some individuals. It is given via intradermal injection (1). about 4 weeks after the injection a local skin reaction is produced and there may be regional

2010 GP Notebook

2496. chronic obstructive pulmonary disease (diagnosis of)

chronic obstructive pulmonary disease (diagnosis of) chronic obstructive pulmonary disease (diagnosis of) - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search chronic obstructive pulmonary disease (diagnosis of) Think of diagnosis of COPD in patients who are (1,2): over 35 and smokers or ex-smokers and have any of these symptoms: exertional breathlessness chronic cough regular sputum production frequent winter ’bronchitis (...) with mild airflow obstruction **Or FEV1 Celli BR, MacNee W (2004) Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. European Respiratory Journal 23(6): 932-46. Global Initiative for Chronic Obstructive Lung Disease (GOLD) (2008) Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease Reference: (1) (2) (3) Links: General Practice Notebook General Practice Notebook The information provided herein should

2010 GP Notebook

2497. Martin-Bell syndrome

Martin-Bell syndrome Martin-Bell syndrome - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search Martin-Bell syndrome The fragile X syndrome is said to be the most common heritable cause of mental retardation after Down's syndrome. It is caused by a dominant X-linked gene with a penetrance of only 50% in females. The gene which is most commonly responsible is FMR-1 (familial mental retardation 1). The disease occurs when (...) the expression of FMR-1 is disrupted by: a large number, more than 230, of trinucleotide repeats a deletion (rare) It seems that loss of fmr-1 results in the fragile X syndrome. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution

2010 GP Notebook

2498. oral contraceptives and cardiovascular (CV) risk

linked item) Reference: Drug and Therapeutics Bulletin (2000); 38 (1): 1-5. MeReC Bulletin 2006;17(2):1-9. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly (...) oral contraceptives and cardiovascular (CV) risk oral contraceptives and cardiovascular (CV) risk - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search oral contraceptives and cardiovascular (CV) risk the current evidence suggests that there is no detectable increase in the risk of myocardial infarction with either second- or third-generation pills in women with no additional risk factors a Drug and Therapeutics bulletin review

2010 GP Notebook

2499. CHD and combined oral contraceptives

Bulletin (2000); 38 (1): 1-5. MeReC Bulletin 2006;17(2):1-9. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives (...) CHD and combined oral contraceptives CHD and combined oral contraceptives - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search CHD and combined oral contraceptives the current evidence suggests that there is no detectable increase in the risk of myocardial infarction with either second- or third-generation pills in women with no additional risk factors a Drug and Therapeutics bulletin review (1) suggests that the risk

2010 GP Notebook

2500. fragile X syndrome

fragile X syndrome fragile X syndrome - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search fragile X syndrome The fragile X syndrome is said to be the most common heritable cause of mental retardation after Down's syndrome. It is caused by a dominant X-linked gene with a penetrance of only 50% in females. The gene which is most commonly responsible is FMR-1 (familial mental retardation 1). The disease occurs when (...) the expression of FMR-1 is disrupted by: a large number, more than 230, of trinucleotide repeats a deletion (rare) It seems that loss of fmr-1 results in the fragile X syndrome. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution

2010 GP Notebook

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