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Family Practice Notebook Updates 2016

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2461. stroke and oral contraceptives

); 38 (1): 1-5. MeReC Bulletin 2006;17(2):1-9. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from (...) stroke and oral contraceptives stroke and oral contraceptives - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search stroke and oral contraceptives the current evidence suggests that there is no detectable increase in the risk of myocardial infarction with either second- or third-generation pills in women with no additional risk factors a Drug and Therapeutics bulletin review (1) suggests that the risk of myocardial infarction

2010 GP Notebook

2462. combined pill and cardiovascular risk

Bulletin (2000); 38 (1): 1-5. MeReC Bulletin 2006;17(2):1-9. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives (...) combined pill and cardiovascular risk combined pill and cardiovascular risk - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search combined pill and cardiovascular risk the current evidence suggests that there is no detectable increase in the risk of myocardial infarction with either second- or third-generation pills in women with no additional risk factors a Drug and Therapeutics bulletin review (1) suggests that the risk

2010 GP Notebook

2463. furuncle

and may be a presenting feature of type 2 diabetes. Reference: Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives (...) furuncle furuncle - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search furuncle This is a perifollicular bacterial infection which is usually caused by staphylococci aureus. It is a type of abscess (1). Boils are often found over the hair bearing areas of the skin (1) - face, neck, breast, axilla or buttocks. Unlike in folliculitis where the inflammation is more superficial and pus is seen in the epidermis, suppuration

2010 GP Notebook

2464. thyroid cancer

thyroid cancer thyroid cancer - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search thyroid cancer Thyroid carcinoma is rare, having an annual incidence of about 3-5 per 100,000. thyroid cancer accounts for about 0.4% of all cancer deaths. women are affected more commonly than men in a ratio of 2-3:1 most likely to develop in women of reproductive age usually presents as a solitary nodule in a patient with normal thyroid (...) there are two rare types which occur in the elderly about 1% of patients have lymphoma of the thyroid, which presents as a rapidly expanding mass and is usually diagnosed on the basis of the patient’s history, together with a tissue diagnosis many of these patients can be cured 3% of patients who have anaplastic thyroid cancer, which presents in a similar way and must be differentiated from lymphoma with a biopsy prognosis is poor Reference: Links: General Practice Notebook General Practice Notebook

2010 GP Notebook

2465. Simon Broome classification in FH

with premature CHD (men < 55 years and women < 65 years) are screened for lipids. Reference: Public Health England (August 2018).Familial Hypercholesterolaemia Implementing a systems approach to detection and management. JBS2: Joint British Societies' guidelines on prevention of cardiovascular disease in clinical practice. Heart 2005; 91 (Supp 5). Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition (...) Simon Broome classification in FH Simon Broome classification in FH - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search Simon Broome classification in FH This is an autosomal dominant disorder of chromosome 19 with homozygous and heterozygous forms; the latter occurs in one in 500 people (meaning that approximately 110,000 people are affected in the UK) (1). It is defined in the WHO classification as a type IIa

2010 GP Notebook

2466. Martin Bell syndrome

Martin Bell syndrome Martin Bell syndrome - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search Martin Bell syndrome The fragile X syndrome is said to be the most common heritable cause of mental retardation after Down's syndrome. It is caused by a dominant X-linked gene with a penetrance of only 50% in females. The gene which is most commonly responsible is FMR-1 (familial mental retardation 1). The disease occurs when (...) the expression of FMR-1 is disrupted by: a large number, more than 230, of trinucleotide repeats a deletion (rare) It seems that loss of fmr-1 results in the fragile X syndrome. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution

2010 GP Notebook

2467. lipid-lowering treatment in primary prevention

), fibrate, nicotinic acid or omega-3 fatty acid compound with a statin for the primary or secondary prevention of CVD ezetimibe prescribe in line with NICE guidance - see linked item Reference: Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions (...) lipid-lowering treatment in primary prevention lipid-lowering treatment in primary prevention - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search lipid-lowering treatment in primary prevention Before starting statin treatment perform baseline blood tests and clinical assessment, and treat comorbidities and secondary causes of dyslipidaemia. Include all of the following in the assessment: smoking status alcohol consumption

2010 GP Notebook

2468. mefloquine in malaria prophylaxis

mefloquine in malaria prophylaxis mefloquine in malaria prophylaxis - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search mefloquine in malaria prophylaxis Mefloquine in malaria prophylaxis acts as a suppressive prophylactic an option for prophylaxis in areas where falciparum malaria highly resistant to chloroquine is seen e.g. East and Central Africa adult dose is mefloquine 250mg per week " mefloquine should not be prescribed (...) to their mental state during mefloquine chemoprophylaxis, they should stop taking mefloquine immediately and seek urgent medical advice The summary of product characteristics must be consulted before prescribing this drug. Reference: Roche (October 2013). Direct Helathcare Professional Communication on Larium (mefloquine) for malaria chemoprophylaxisis and the risk of neuropsychiatric adverse reactions Links: General Practice Notebook General Practice Notebook The information provided herein should

2010 GP Notebook

2469. antiepileptic treatment in epilepsy

General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data (...) antiepileptic treatment in epilepsy antiepileptic treatment in epilepsy - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search antiepileptic treatment in epilepsy Anticonvulsant drugs (AEDs) are the mainstay of antiepileptic drug therapy (1). NICE (1) state that: an epilepsy specialist should: recommend initiation of appropriate AED treatment plan continuation of treatment manage, or provide guidance, for withdrawal

2010 GP Notebook

2470. spherocytosis (hereditary)

and increased numbers of reticulocytes on the peripheral blood smear. There is usually a positive family history. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly (...) spherocytosis (hereditary) spherocytosis (hereditary) - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search spherocytosis (hereditary) Hereditary spherocytosis is a disorder of the red blood cell membrane, leading to haemolytic anaemia. It is inherited as an autosomal dominant condition often linked to chromosome 8. It affects about 1 in every 5000 individuals in the United States. The disorder is characterised by spherocytosis

2010 GP Notebook

2471. American trypanosomiasis

General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data (...) American trypanosomiasis American trypanosomiasis - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search American trypanosomiasis Chagas' disease is caused by Trypanosoma cruzi, which is spread by Reduviid bugs. American Trypanosomiasis or Chagas disease is an endemic disease mainly in Central and South America it is a zoonosis caused by the flagellated protozoan Trypanosoma cruzi (T. cruzi). In endemic areas, the primary route

2010 GP Notebook

2472. hereditary spherocytosis

and increased numbers of reticulocytes on the peripheral blood smear. There is usually a positive family history. Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly (...) hereditary spherocytosis hereditary spherocytosis - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search hereditary spherocytosis Hereditary spherocytosis is a disorder of the red blood cell membrane, leading to haemolytic anaemia. It is inherited as an autosomal dominant condition often linked to chromosome 8. It affects about 1 in every 5000 individuals in the United States. The disorder is characterised by spherocytosis

2010 GP Notebook

2473. primary lateral sclerosis

General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data (...) primary lateral sclerosis primary lateral sclerosis - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search primary lateral sclerosis This is a form of motor neurone disease (MND). It is the most common form of MND and accounts for 65% to 85% of all cases of MND (1). Amyotrophic lateral sclerosis results from lesions to the corticospinal tract and the anterior horn cells and produces the characteristic feature of tonic atrophy

2010 GP Notebook

2474. diabetes and pregnancy

Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your (...) diabetes and pregnancy diabetes and pregnancy - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search diabetes and pregnancy Gestational diabetes now includes both gestational impaired glucose tolerance and gestational diabetes mellitus (1). approximately 700,000 women give birth in England and Wales each year, and up to 5% of these women have either pre-existing diabetes or gestational diabetes of women who have diabetes during

2010 GP Notebook

2475. gestational diabetes

Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your (...) gestational diabetes gestational diabetes - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search gestational diabetes Gestational diabetes now includes both gestational impaired glucose tolerance and gestational diabetes mellitus (1). approximately 700,000 women give birth in England and Wales each year, and up to 5% of these women have either pre-existing diabetes or gestational diabetes of women who have diabetes during

2010 GP Notebook

2476. DM and pregnancy

Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your (...) DM and pregnancy DM and pregnancy - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search DM and pregnancy Gestational diabetes now includes both gestational impaired glucose tolerance and gestational diabetes mellitus (1). approximately 700,000 women give birth in England and Wales each year, and up to 5% of these women have either pre-existing diabetes or gestational diabetes of women who have diabetes during pregnancy

2010 GP Notebook

2477. Chagas' disease

Chagas' disease Chagas' disease - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search Chagas' disease Chagas' disease is caused by Trypanosoma cruzi, which is spread by Reduviid bugs. American Trypanosomiasis or Chagas disease is an endemic disease mainly in Central and South America it is a zoonosis caused by the flagellated protozoan Trypanosoma cruzi (T. cruzi). In endemic areas, the primary route of transmission is vector (...) , Rocha DD, Jurberg J. A checklist of the current valid species of the subfamily Triatominae Jeannel, 1919 (Hemiptera, Reduviidae) and their geographical distribution, with nomenclatural and taxonomic notes: Magnolia Press, 2003. Kirchhoff LV (1993). American trypanosomiasis (Chaga's disease) - a tropical disease in the United States, NEJM, 329, 639-643. Control of Chaga's disease:report of WHO expert committee. WHO Tech Rep Ser 1991;811:27-37. Links: General Practice Notebook General Practice

2010 GP Notebook

2478. Creutzfeldt - Jacob disease

Creutzfeldt - Jacob disease Creutzfeldt - Jacob disease - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search Creutzfeldt - Jacob disease Creutzfeldt-Jacob disease (CJD) is the name given to the most common group of human prion diseases. The component diseases are: sporadic CJD iatrogenic CJD familial CJD new variant CJD Links: General Practice Notebook General Practice Notebook The information provided herein should (...) not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial independence. GPnotebook stores small data files on your computer called cookies so that we can recognise you

2010 GP Notebook

2479. maternal diabetes in pregnancy

) (3) Links: General Practice Notebook General Practice Notebook The information provided herein should not be used for diagnosis or treatment of any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions. Copyright 2016 Oxbridge Solutions Ltd®. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions Ltd® receives funding from advertising but maintains editorial (...) maternal diabetes in pregnancy maternal diabetes in pregnancy - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search maternal diabetes in pregnancy Gestational diabetes now includes both gestational impaired glucose tolerance and gestational diabetes mellitus (1). approximately 700,000 women give birth in England and Wales each year, and up to 5% of these women have either pre-existing diabetes or gestational diabetes of women

2010 GP Notebook

2480. lateral sclerosis

lateral sclerosis lateral sclerosis - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search lateral sclerosis This is a form of motor neurone disease (MND). It is the most common form of MND and accounts for 65% to 85% of all cases of MND (1). Amyotrophic lateral sclerosis results from lesions to the corticospinal tract and the anterior horn cells and produces the characteristic feature of tonic atrophy - brisk reflexes (...) ) prospective analysis of a series of PLS case reports was in agreement with data from other studies suggesting that pure PLS cases have a prolonged course of disease with a high level of independence when compared to other MND (3) Reference: (1) NICE (January 2001). Guidance on the Use of Riluzole (Rilutek) for the treatment of Motor Neurone Disease. (2) (3) (4) Orrell, R. & deBelleroche, JS. Superoxide dismutase and ALS. Lancet 1994;344: 1651-2. Links: General Practice Notebook General Practice Notebook

2010 GP Notebook

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