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Diabetic Mice Show an Aggravated Course of Herpes-Simplex Virus-Induced FacialNerveParalysis. Bell's palsy is highly associated with diabetes mellitus.The cause of Bell's palsy in diabetes mellitus is not completely understood. Diabetic mononeuropathy or reactivation of herpes simplex virus type 1 (HSV-1) may be responsible for the facialparalysis seen in diabetic patients. We previously reported transient and ipsilateral facialparalysis in mice inoculated with HSV-1. In this study, we (...) increased in the diabetic mice. Electrophysiologic examinations and histopathologic changes also revealed that the facialnerve damage was more severe in the diabetic group.The aggravated course of HSV-1 infection in diabetes suggests that HSV-1 may be the main causative factor for the increased incidence of facialparalysis in diabetic patients.
WITHDRAWN: Corticosteroids for Bell's palsy (idiopathic facialparalysis). Inflammation and oedema of the facialnerve are implicated in causing Bell's palsy. Corticosteroids have a potent anti-inflammatory action which should minimise nerve damage and thereby improve the outcome of patients suffering from this condition.The objective of this review was to assess the effect of steroid therapy in the recovery of patients with Bell's palsy.We searched the Cochrane Neuromuscular Disease Group (...) concealment was appropriate in two trials, and the data reported allowed an intention-to-treat analysis. The data included in the meta-analyses were collected from three trials with a total of 117 patients. Overall 13/59 (22%) of the patients allocated to steroid therapy had incomplete recovery of facial motor function six months after randomisation, compared with 15/58 (26%) in the control group. This reduction was not significant (relative risk 0.86, 95% confidence interval 0.47 to 1.59). The reduction
FacialNerve Laceration and its Repair Facialparalysis is a devastating condition with profound functional, aesthetic and psychosocial consequences. Tumors within or outside the skull, Bell's palsy and trauma are the most common causes of facialparalysis in adults.Our patient was a 35-year-old man with deep laceration wounds. The patient was taken to the operating room and the nerves were repaired. We observed gradual improvement of muscle performance except branches of the frontal (...) nerve.Complete rupture of the facialnerve is challenging and the treatment is surgery, which requires careful planning.
patients completed a minimal follow up of 24 months at the time of evaluation and were included in the study population. Facialnerveparalysis was present for a mean duration of 11.3 months (range 2-42 months) and all the patients had a HB grade VI prior their surgery. Final facialnerve motor function. The most common cause of facialparalysis was vestibular Schwannoma surgery. All the patients achieved a postoperative HB grade III or IV after a mean follow-up time of 20 months. The facial movements (...) were detected after a period that ranged from ranged from 5 to 9 months. Only 4 patients suffered from difficulties during eating and drinking and three of them had associated lower cranial nerve deficit. Despite the various techniques in facial reanimation following total facialnerveparalysis, the end to end of hypoglossal to facialnerve anastomosis remains one of the best treatments in cases of viable distal facial stump and nonatrophic musculature.
Profile of facial palsy in Arar, northern Saudi Arabia The term facial palsy generally refers to weakness of the facial muscles, mainly resulting from temporary or permanent damage to the facialnerve. Common causes of facialparalysis include infection or inflammation of the facialnerve, head trauma, head or neck tumor, stroke.To outline the incidence of several etiologies and the profile of patients with peripheral facialparalysis attending the outpatient clinic of the neurology department (...) in Hospitals of Arar City, Saudi Arabia.This cross-sectional study was carried out in Arar city from October 2016 to May 2017. The study was conducted in the outpatient clinic of the neurology department in hospitals of Arar City. Any ages of both sexes of all newly diagnosed unilateral facial palsy were included in the study. Data were analyzed by SPSS version 15, using descriptive statistics and Chi-square test. P-value was considered significant if <0.05.The mean age of the facial palsy cases was 33.65
= Central Nervous System + Peripheral Nervous System PNS divided into 12 cranial nerves (Remember episode 105?) 31 spinal nerves (8 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 1 coccygeal). Almost all of these nerves have Sensory, Motor and autonomic function Anatomically / functionally speaking the autonomic nervous system is divided into: Sympathetic (thoracolumbar) component Parasympathetic (craniosacral) component. Note: Autonomic dysfunction may cause systemic abnormalities (e.g., Orthostasis (...) Asymmetrical  List 8 causes of acute emergent weakness and possible respiratory compromise See box 97.1 in Rosen’s 9 th Edition for causes of acute, emergent weakness and possible respiratory compromise Autoimmune Demyelinating Guillain-Barré syndrome (GBS) Chronic inflammatory demyelinating polyneuropathy Myasthenia gravis Toxic Botulism Buckthorn Seafood Paralytic shellfish toxin Tetrodotoxin (puffer fish, newts) Tick paralysis Metals Arsenic Thallium Metabolic Dyskalemic syndromes Acquired
Rehabilitation of Central FacialParalysis With Hypoglossal-Facial Anastomosis. To evaluate the ability of hypoglossal-facialnerve anastomosis to reanimate the face in patients with complete nuclear (central) facialnerve palsy.Retrospective case series.Tertiary academic medical center.Four patients with complete facialnerveparalysis due to lesions of the facial nucleus in the pons caused by hemorrhage due to arteriovenous or cavernous venous malformations, stroke, or injury after tumor (...) /VI, and 25% had HB grade IV/VI. Average facial disability index scores were 61.25 for physical function and 78 for social/well-being, comparable to results from complete hypoglossal-facial anastomosis after peripheral facialnerve palsy after acoustic neuroma resection.Patients with nuclear facialparalysis who undergo end-to-end hypoglossal-facialnerve anastomosis achieve similar degrees of reanimation compared with those with peripheral facialnerve palsies. This raises the intriguing
Give me a kiss! An integrative rehabilitative training program with motor imagery and mirror therapy for recovery of facial palsy. Peripheral facialnerve palsy (FNP) can have various causes, such as Bell's palsy or after surgery for acoustic neuroma. Rehabilitation is often required but there is no evidence that any rehabilitation approach is more efficacious than another.The purpose of this research was to determine the effects of neurocognitive-rehabilitative approach through mirror-therapy (...) of patients with unilateral facialparalysis to recognize and appropriately judge facial expressions and perceive the judgments of others remains underexplored. The likelihood of recovering near-normal facial-function after grade VI facialparalysis is low. Procedures, such as the immediate repair of the facialnerve with an interposed donor graft, might improve facial function in patients with partially injured facialnerves.
Polytetrafluoroethylene granuloma-associated facial palsy following microvascular decompression. Microvascular decompression (MVD) may be employed in the management of hemifacial spasm (HFS), wherein a pledget of polytetrafluoroethylene (i.e., Teflon, Chemours, Wilmington DE) is sometimes introduced to separate an offending vessel from the cisternal segment of facialnerve. Rarely, Teflon may cause a granulomatous reaction resulting in nerve palsy. We here present the first case series (...) of facial palsy thought to be secondary to Teflon granuloma following MVD for HFS.A data repository of 1,312 patients with facial palsy was reviewed to identify individuals who had previously undergone MVD for HFS. Data collected include age at time of MVD, age at onset of facial weakness and at presentation, House-Brackmann scores, clinician-graded facial function using the Electronic FacialParalysis Assessment scale, imaging findings, and therapeutic interventions and outcomes.Six patients meeting
Recurrent and Progressive Facial Baroparesis on Flying Relieved by Eustachian Tube Dilation. Facial baroparesis is a rare phenomenon of seventh cranial nerve palsy traditionally reported in divers, with only 11 cases reported in aviation so far. It is important to correctly diagnose facial baroparesis given the differential diagnosis of stroke and decompression disease and offer appropriate treatment for recurrent cases.The authors present the case of a patient with recurrent and progressive (...) facial baroparesis treated with Eustachian tube balloon dilation. Institutional medical records were reviewed, and analysis of the current literature was performed.A 37-year-old woman experienced recurrent and progressive left facialparalysis on descent from altitude on commercial airline flights, with resolution between flights. The patient flew frequently for work-related trips and for the past 7 years had noted facialparalysis that began with mild asymmetry of the face and progressed
cases of facialparalysis. [ ] The incidence of facialparalysis in live births is 0.8-2.1 per 1000 births, and, of these, 88% are associated with a difficult labor. Of patients with birth trauma, 67-91% are associated with forceps delivery. [ , , ] Developmental causes include those associated with syndromes and teratogens. An example of a development cause is , which has an incidence of 1 per 50,000 births. [ ] A common disorder that resembles a unilateral partial nerveparalysis is congenital (...) unilateral lower lip palsy (CULLP), also known as neonatal asymmetric crying facies, that occurs in 1 out of 160 live births. [ ] The estimated prevalence of facioscapulohumeral muscular dystrophy (FSH MD) is between 1/20,000 and 1/8000, making it the world’s third-most-common inherited myopathy. [ ] Previous Next: Etiology The cause of congenital facialparalysis is associated with either a traumatic injury or developmental deformities of the brain or facialnerve (cranial nerve VII). [ ] Trauma
Suspension for FacialParalysis Updated: Oct 26, 2018 Author: Suzanne K Doud Galli, MD, PhD; Chief Editor: Arlen D Meyers, MD, MBA Share Email Print Feedback Close Sections Sections Static Suspension for FacialParalysis Overview Background The mimetic muscles direct facial movements. Under the control of the seventh cranial nerve (CN VII), the movement of these muscles correlates with the communication of human thought, emotion, and expression. Loss of this capacity is disfiguring and dysfunctional (...) include the extensor digitorum brevis, gracilis, latissimus dorsi, pectoralis minor, and serratus anterior. The advantage of free muscle transfer over regional muscle transfer has not been established. Previous Next: Etiology The various etiologies of facialparalysis can be classified into 3 major groups, ie, intracranial, intratemporal, and extracranial (see Relevant Anatomy). Regardless of the cause, the importance of establishing the degree and duration of weakness when evaluating a patient must
> Dynamic Reanimation for FacialParalysis Updated: Jan 09, 2019 Author: Steven M Parnes, MD; Chief Editor: Arlen D Meyers, MD, MBA Share Email Print Feedback Close Sections Sections Dynamic Reanimation for FacialParalysis Overview Background Facialparalysis can be a consequence of traumatic facialnerve injury, iatrogenic causes, malignancy, congenital syndromes, and viral infections. Prolonged paralysis can result in ocular complications, articulation difficulties, impaired feeding, and difficulty (...) in conveying emotion through expressive movement. Numerous reanimation techniques are available to restore function and are based on the cause of the facialparalysis, type of injury, its location, and the anticipated duration. These methods are broadly classified into 4 types as follows: (1) neural methods, (2) musculofascial transpositions, (3) microneurovascular transfer (4) facial plastic procedures, and (5) prosthetics. The most desirable procedures to reestablish the mimetic control of the face
Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Facies ParalysisFacialParalysis Bell Palsy Disease Attributes Pathologic Processes Neurologic Manifestations Nervous System Diseases Signs and Symptoms Mouth Diseases Stomatognathic Diseases Herpesviridae Infections DNA Virus Infections Virus Diseases FacialNerve Diseases Cranial Nerve Diseases (...) prognosis is not engaged in this pathology. Facial palsy remains a personal drama for patient. Consequences may take the form of: aesthetic deformation, modification of body image, with socio-professional consequences. Beside unsightly facial aspects, weakness of facial muscles can cause troubles in eating, drinking, talking, communicating personal emotions and communication. Facial palsy impacts patients' quality of life (QOL) and affects mental health. This wide multidimensional concept usually
called crotoxin, or the "canebrake toxin," which is a potent β-neurotoxin affecting presynaptic nerves that can causeparalysis by inhibiting appropriate neuromuscular transmission. We present an unusual case of an 8-year-old boy bitten twice on his calf by a timber rattlesnake, who presented with a life-threatening envenomation and suffered multisystem organ failure as well as a prominent presynaptic neurotoxicity resulting in facial diplegia, pharyngeal paralysis, and ophthalmoplegia. (...) Facial diplegia, pharyngeal paralysis, and ophthalmoplegia after a timber rattlesnake envenomation. The timber rattlesnake, also known as Crotalus horridus, is well known to cause significant injury from toxins stored within its venom. During envenomation, toxic systemic effects immediately begin to cause damage to many organ systems including cardiovascular, hematologic, musculoskeletal, respiratory, and neurologic. One defining characteristic of the timber rattlesnake is a specific neurotoxin
Cranial and Cervical Muscular Weakness in Mitochondrial Myopathy Is Associated With Resolution of Migraine Headaches: Further Evidence That Muscular Compression of Cranial and Peripheral Nerves Is a Cause of Headache in a Subset of Patients With Migraine A significant subset of patients with migraine headaches has pain relief after neuroplasty/muscular decompression of select cranial and cervical nerves. In the majority of cases, compression occurs secondary to compression of the nerves (...) by adjacent muscles. Previous studies have shown that both surgical decompression and chemical denervation (eg, botulinum toxin) provide relief of migraine headaches; however, controversy remains. If some migraine headaches are caused by muscular compression, then paresis of the compressing muscles by underlying myopathic/metabolic disease should result in migraine relief in some patients.We report a case of mitochondrial myopathy causing weakness primarily of the muscles of facial expression and the neck
, letter, editorial material, discussion, book chapter. (4) Publication year: 1992-2011 inclusive.(1) Articles on the causes and diagnosis on facialparalysis; (2) Type of articles: correction; (3) Articles from following databases: all databases related to social science and chemical databases in Web of Science.(1) Overall number of publications; (2) number of publications annually; (3) number of citations received annually; (4) top cited paper; (5) subject categories of publication; (6) the number (...) Literature study on clinical treatment of facialparalysis in the last 20 years using Web of Science: Comparison between rehabilitation, physiotherapy and acupuncture Facialparalysis is defined as severe or complete loss of facial muscle motor function.The study was undertaken to explore a bibliometric approach to quantitatively assess the research on clinical treatment of facialparalysis using rehabilitation, physiotherapy and acupuncture using Web of Science from 1992 to 2011.Bibliometric
Facialnerve palsy after reactivation of herpes simplex virus type 1 in diabetic mice. Bell's palsy is highly associated with diabetes mellitus (DM). Either the reactivation of herpes simplex virus type 1 (HSV-1) or diabetic mononeuropathy has been proposed to cause the facialparalysis observed in DM patients. However, distinguishing whether the facial palsy is caused by herpetic neuritis or diabetic mononeuropathy is difficult. We previously reported that facialparalysis was aggravated in DM (...) mice after HSV-1 inoculation of the murine auricle. In the current study, we induced HSV-1 reactivation by an auricular scratch following DM induction with streptozotocin (STZ).Controlled animal study.Diabetes mellitus was induced with streptozotocin injection in only mice that developed transient facialnerveparalysis with HSV-1. Recurrent facial palsy was induced after HSV-1 reactivation by auricular scratch.After DM induction, the number of cluster of differentiation 3 (CD3)(+) T cells
Small Vestibular Schwannomas Presenting with FacialNerve Palsy. To describe the surgical management and convalescence of two patients presenting with severe facialnerve weakness associated with small intracanalicular vestibular schwannomas (VS).Retrospective review.Two adult female patients presenting with audiovestibular symptoms and subacute facialnerveparalysis (House-Brackmann Grade IV and V). In both cases, post-contrast T1-weighted magnetic resonance imaging revealed an enhancing (...) cause severe facial neuropathy, mimicking the presentation of facialnerve schwannomas and other less common pathologies. In the absence of labyrinthine extension on MRI, surgical exploration is the only reliable means of establishing a diagnosis. In the case of confirmed VS, early gross total resection with facialnerve preservation and labyrinthine segment decompression may afford full motor recovery-an outcome that cannot be achieved with facialnerve grafting.