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Facial Nerve Paralysis Causes

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181. Clinical Efficacy of Platelet-Rich Plasma in the Treatment of Neurotrophic Corneal Ulcer (PubMed)

of 25 patients with nonhealing corneal ulcers due to herpes simplex or herpes zoster infection and facial nerve or trigeminal nerve paralysis as a result of a neurosurgical operation caused by a tumour or stroke. The patients were given autologous platelet-rich plasma drops five times a day and additionally preservative-free artificial tears and a vitamin A ointment at night for maximum 3 months. The following were evaluated: best corrected visual acuity (BCVA), healing of corneal surface

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2018 Journal of ophthalmology

182. Submental Study (Sequential Treatment Approach)

in the neck or chin area within 6 months before the first treatment session. Subject has a known history of cryoglobulinemia, cold urticaria, paroxysmal cold hemoglobinuria or cold agglutinin disease. Subject has a known history of Raynaud's disease, or any known condition with a response to cold exposure that limits blood flow to the skin. Subject has a history of facial nerve paresis or paralysis (such as Bell's palsy) Subject has a history or current symptoms of dysphagia. Subject has a history (...) Self Rating Scale (SSRS) as determined at Screening visit. History of stable body weight confirmed by the subject, for at least 6 months prior to the first treatment session. Subject agrees to maintain his/her weight (i.e., within 5%) by not making any major changes in their diet or exercise routine during the course of the study. Subject agrees to forgo any treatment or behavior (e.g., unshaven facial hair) during the subject's participation in the study that may affect the assessments

2018 Clinical Trials

183. Intratympanic Steroid for Bell's Palsy

Inclusion Criteria: English as primary language Acute unilateral facial palsy without skin lesions which developed within a 72-hour period and is present for 21 days or less. Moderate to severe facial palsy [House-Brackmann grade IV or greater] Exclusion Criteria: Another cause of facial nerve paralysis that is not idiopathic Otologic disease including otitis media, temporal bone fracture, a previous history of facial nerve palsy in either side, history of otologic surgery, and suspected Ramsay Hunt (...) , University of Missouri-Columbia Study Details Study Description Go to Brief Summary: Facial nerve paralysis is due to inflammation around the facial nerve. Current treatment for facial nerve paralysis is a 10 day course of oral steroids (which will reduce the inflammation), with electrodiagnostic testing. There have been limited studies on the use of intratympanic steroid injection, in addition to oral steroid, in the recovery of facial nerve paralysis. There are indications that the use of intratympanic

2018 Clinical Trials

184. Vestibular Evaluation After Vestibular Schwannoma Treatment

, University Hospital, Grenoble Study Details Study Description Go to Brief Summary: Vestibular schwannoma is a benign tumor located on the vestibular nerve. Patient could present dizziness symptoms cause to the tumor, and at least after the treatment by gamaknife radiosurgery or microsurgery resection. Only few studies keep the interest about dizziness symptoms and treatment modality in vestibular schwannoma. In the study dizziness symptoms were compared before and after the treatment of vestibular (...) a standarised scale : - Dizziness Functionnal Scale (AAO), this is a scale quote from 1 (no symptoms of dizzyness) to 6 (major disability). The patient have to choise only one item that correspond to the condition. The scale is completed before and after the treatement. The investigator send the scale to the patient by mail way. Secondary Outcome Measures : Facial fonction [ Time Frame: From 4 years to 6 months ] House and Brackmann scale : This scale is a standarised assessment of facial fonction from

2018 Clinical Trials

185. Screening and Characterization of Hearing Disorders in Diabetic Persons

frequently characterized by facial paralysis or motor eye nerves. The association between hearing disorders and diabetes has always aroused controversy on the part of contradictory literature data. Are hearing disorders an underestimated complication of diabetes? A recent meta-analysis of 2013, examined the scientific literature between 1950 and 2011 and of the 3158 citations, only 13 articles were selected (with more than 20 000 participants). This study found that hearing disorders in diabetic patients (...) See Sponsor: University Hospital, Clermont-Ferrand Information provided by (Responsible Party): University Hospital, Clermont-Ferrand Study Details Study Description Go to Brief Summary: Diabetes is now the most common chronic disease, affecting nearly 6% of the population in Western populations. Diabetic neuropathy is a priori the most common and the most common specific complications of diabetes. It can of course touch the lower limbs, the vegetative nervous system as well as the cranial nerves

2018 Clinical Trials

186. Radiation Exposure and Bell’s Palsy: A Hypothetical Association (PubMed)

Radiation Exposure and Bell’s Palsy: A Hypothetical Association Bell's palsy is an idiopathic peripheral nerve palsy involving the facial nerve. It accounts for 60 to 75% of all cases of unilateral facial paralysis. The main mechanisms to induce BP remain unclear, but infection, ischemic condition and immunodeficiency may contribute to the development of Bell's palsy. Accumulating evidence has shown several factors can trigger the reactivation of latent HSV including psychological stressors (...) , physical stressors and immunosuppression. Ionization and non-ionization radiations are of importance of physical stressors. Some data have shown radiation can reactivate HSVs. Based on preliminary studies showing radiation reactivation of HSVs, we aimed to hypothesize radiation (in both forms of ionization and non-ionization) may cause Bell's palsy. In the future, the role of radiotherapy, radiofrequency radiation from mobile phones and wireless devices in HSV reactivation and Bell's palsy should

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2018 Journal of Biomedical Physics & Engineering

187. Comparison of the application of artificial ossicles and autologous ossicles in the reconstruction of a damaged ossicular chain. (PubMed)

in 16 cases; the average air-bone gap was 33.4 ± 4.5 dB pre-operatively and 17.8 ± 7.8 dB post-operatively.Ossicular chain reconstruction is an effective way of improving hearing in patients with ossicular chain damage. The results suggest that repair with either the titanium partial ossicular reconstruction prosthesis or autologous ossicles can improve hearing following ossicular chain injury with facial nerve paralysis caused by a temporal bone fracture. (...) Comparison of the application of artificial ossicles and autologous ossicles in the reconstruction of a damaged ossicular chain. To evaluate the therapeutic effect that the titanium partial ossicular reconstruction prosthesis and autologous ossicles have on hearing loss after reconstruction of a damaged ossicular chain.Forty-two medical records of treatments carried out from 2013 to 2015 for ossicular chain damage with facial nerve paralysis due to temporal bone fractures were reviewed

2018 Journal of Laryngology & Otology

188. Canadian clinical practice guidelines for acute and chronic rhinosinusitis

the standard. Computed tomography (CT) scanning is mainly used to assess potential complications or where regular sinus X-rays are no longer available. Radiology should be considered to confirm a diagnosis of ARBS in patients with multiple recurrent episodes, or to eliminate other causes. 4: Urgent consultation should be obtained for acute sinusitis with unusually severe symptoms or systemic toxicity or where orbital or intracranial involvement is suspected. Option Strong 5: Routine nasal culture (...) is not recommended for the diagnosis of ABRS. When culture is required for unusual evolution, or when complication requires it, sampling must be performed either by maxillary tap or endoscopically-guided culture. Moderate Strong 6 : The 2 main causative infectious bacteria implicated in ABRS are Streptococcus pneumoniae and Haemophilus influenzae. Strong Strong 7: Antibiotics may be prescribed for ABRS to improve rates of resolution at 14 days and should be considered where either quality of life or productivity

2011 CPG Infobase

189. Non-Small Cell Lung Cancer Treatment (PDQ®): Health Professional Version

structures, distant metastases, or paraneoplastic phenomena. The most common symptoms at presentation are worsening cough or chest pain. Other presenting symptoms include the following: Hemoptysis. Malaise. Weight loss. Dyspnea. Hoarseness. Symptoms may result from local invasion or compression of adjacent thoracic structures such as compression involving the esophagus causing dysphagia, compression involving the laryngeal nerves causing hoarseness, or compression involving the superior vena cava causing (...) and Mortality Estimated new cases and deaths from lung cancer (NSCLC and SCLC combined) in the United States in 2019:[ ] New cases: 228,150. Deaths: 142,670. Lung cancer is the leading cause of cancer-related mortality in the United States.[ ] The 5-year relative survival rate from 1995 to 2001 for patients with lung cancer was 15.7%. The 5-year relative survival rate for patients with local-stage (49%), regional-stage (16%), and distant-stage (2%) disease varies markedly, depending on the stage

2016 PDQ - NCI's Comprehensive Cancer Database

190. A blue middle ear mass: Cholesterol granuloma mimicking a glomus tumor and endolymphatic sac tumor. (PubMed)

A blue middle ear mass: Cholesterol granuloma mimicking a glomus tumor and endolymphatic sac tumor. Cholesterol granuloma (CG) is the most common benign lesion of the petrous apex, however, it can grow significantly large and become destructive causing a diagnostic dilemma. This case presents a 25-year-old female with 2-year history of left-sided progressive and profound hearing loss, a transient left-sided facial paralysis and cranial nerve 10 palsy who presented with a blue middle ear mass

2017 American Journal of Otolaryngology

191. The Protean Neuropsychiatric and Vestibuloauditory Manifestations of Neurosarcoidosis. (PubMed)

The Protean Neuropsychiatric and Vestibuloauditory Manifestations of Neurosarcoidosis. A rare subset of sarcoidosis, neurosarcoidosis, is reported to occur in 5-7% of sarcoid patients and can manifest in a variety of ways. The most common are facial paralysis and optic neuritis, less commonly causing cochleovestibulopathy, blindness, anosmia, and other cranial nerve (CN) palsies. The sensory deficit may be severe and psychiatric symptoms may result from the effects of the disease or steroid (...) and XI, with altered mental status requiring admission following high-dose intravenous corticosteroids. The third is a 15-year-old boy who presented with sudden, bilateral, profound SNHL, recurrent headaches, and left facial weakness refractory to antivirals, ultimately diagnosed with neurosarcoidosis following an aborted cochlear implantation where diffuse inflammation was found, and histopathology revealed Schaumann bodies; he was treated with methotrexate and later underwent successful cochlear

2017 Audiology & Neuro-Otology

192. "Vertical Midface Lifting with Periorbital Anchoring in the Management of Lower Eyelid Retraction: A Ten-Year Clinical Retrospective Study". (PubMed)

on between January of 2004 and January of 2014. The various causes of eyelid retraction in this population included cosmetic blepharoplasty (56.8 percent), involutional ectropion (23.1 percent), tumor resection (9.5 percent), facial nerve paralysis (8.5 percent), and trauma and related surgery (2 percent). The study was restricted exclusively to cases of moderate and severe lower eyelid retraction addressed by means of midface lifting. The mean follow-up time was 16.8 months. All of the patients were

2017 Plastic and reconstructive surgery

193. Zika virus and neurological disease: is there evidence for causality?

in a French Polynesian lady, clinically presenting as global tetraparesis, facial paralysis, and autonomic nervous system dysfunction[4]. Subsequently, a further 42 GBS cases secondary to Zika virus infection have been reported, with Zika virus infection preceding the onset of GBS by 6 days [5]. Most patients exhibited a rapid disease course, severe tetraparesis and bilateral facial weakness, with an elevated CSF protein level. Respiratory dysfunction, requiring intensive care management, was evident (...) -induced neurotoxicity, with changes noted in neural progenitor cells that are exposed to the virus, providing evidence of biological plausibility. In addition to the neonatal neurological manifestations, Zika virus infections have been associated with the occurrence of Guillain Barre Syndrome (GBS) [3-7], an acute immune-mediatied polyradiculoneuropathy with a heterogeneous phenotype[8], that causes acute weakness and impaired sensation. The first case of ZIKA related GBS was reported in 2013

2016 JNNP blog

194. Cryolipolysis for Jawline Contouring

localized subcutaneous fat, such as swollen lymph nodes or ptotic submandibular glands. Significant enlargement on the anterior neck that may prevent the proper placement of the applicator e.g. enlarged thyroid glands. Treatment with dermal fillers, radiofrequency or laser procedures, or chemical peels in the treatment area (below the mandible) within the past 6 months. Botulinum toxin or other aesthetic drug injections within the treatment area in the past 6 months. History of facial nerve paresis (...) ., within 5%) by not making any major changes in diet or exercise routine during the course of the study. Subject has signed a written informed consent form. Exclusion Criteria Excessive skin laxity in the treatment area for which reduction of subcutaneous fat may, in the opinion of the investigator, result in an unacceptable aesthetic result. Prominent platysmal bands at rest which may interfere with assessment of treatment area. Evidence of any cause of enlargement in the treatment area other than

2017 Clinical Trials

195. The Lateral Tarsal Strip for Paralytic Ectropion in Patients with Leprosy (PubMed)

The Lateral Tarsal Strip for Paralytic Ectropion in Patients with Leprosy In patients with leprosy, paralysis of the facial nerve results in the lower eyelid ectropion and lagophthalmos as a sequela even when the leprosy is cured. Paralytic ectropion causes many functional and cosmetic eye problems, leading to blindness if left untreated.The purpose of this retrospective study is to evaluate the efficacy of surgical correction of paralytic ectropion, the lateral tarsal strip, in patients

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2017 Annals of dermatology

196. Diaphragm Electrical Activity of Preterm Infants on nCPAP With Binasal Prongs Versus RAM Cannula

and requiring less than 35% of oxygen. Exclusion Criteria: Infants with congenital anomalies of the gastrointestinal tract, phrenic nerve damage, diaphragmatic paralysis, esophageal perforation; infants with congenital or acquired neurological deficit (including significant intraventricular hemorrhage greater than Grade II), neonatal seizure; infants with significant congenital heart disease (including symptomatic PDA); infant with congenital anomalies of the diaphragm; infant with congenital anomalies (...) ) may cause nasal-septal injury and discomfort. The RAM cannula is another interface that consists in soft and curved prongs to avoid this nasal injury, but as the seal is not 100%, suboptimal delivery of airway distending pressure could result if they are used to deliver CPAP, as compared to standard interfaces. The investigators plan to study very low birth weight preterm babies who are generally well but require some support with their breathing. By inserting a special feeding tube with sensors

2017 Clinical Trials

197. Botulinum Toxin for Trigeminal Neuralgia

that causes flaccid paralysis by blocking neurotransmitter release by axonal terminals. As a contaminant, it is the cause of potentially lethal botulism poisoning; however, as a drug, it has been widely used in the treatment of dystonia, as well as for non-surgical cosmetic treatment. More recently, studies investigating the ability of BoNT-A to treat pain have been increasing. In 2012, the investigators reported the results of a randomized, double-blind, and placebo-controlled trial in which subcutaneous (...) -regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Neuralgia Trigeminal Neuralgia Peripheral Nervous System Diseases Neuromuscular Diseases Nervous System Diseases Pain Neurologic Manifestations Signs and Symptoms Trigeminal Nerve Diseases Facial Neuralgia Facial Nerve Diseases Mouth Diseases Stomatognathic Diseases Cranial Nerve Diseases Botulinum Toxins Botulinum Toxins, Type A abobotulinumtoxinA Acetylcholine Release

2017 Clinical Trials

198. Funtabulously Frivolous Friday Five 139

caused by spirochetes, such as borreliosis (Lyme disease and tick-borne relapsing fever), leptospirosis, Q fever, bartonellosis (including cat scratch disease), brucellosis, typhoid fever, trichinosis, and cerebral trypanosomiasis. [ ] Question 4 There are two Hutchinson signs , one is important if you are a dermatologist and the other if you are an ophthalmologist. What are they? Hutchinson sign (ophthalmology) relates to involvement of the tip of the nose from facial herpes zoster. It implies (...) basis, is has the potential to kill more humans than any other? Botulinum A toxin There are actually 6 different types (A to F) produced by the spore-forming gram positive bacillus Clostridium botulinum. Botulinum toxin acts presynaptically to prevent the release of acetylcholine. Consequently the effects include autonomic dysfunction and a progressive flaccid paralysis with early bulbar involvement, usually within 2-72 hours. It has an LD50 of 1ng/kg, making it 100,000 more toxic than sarin

2016 Life in the Fast Lane Blog

199. An Update of Comprehensive Evidence-Based Guidelines for Interventional Techniques in Chronic Spinal Pain - Part 2 - Guidance and Recommendations

on history, physical examination, imaging, and nerve conduction studies in non-radicular pain, a precise cause of pain may be identified in only approxi- mately 15% of patients (184-189,367-504). However, it has been described that with application of controlled diagnostic interventional techniques, a diagnosis may become a reality in 85% of the patients rather than 15% (11,13,15,17,26,33,36-38,111,383,384). Consequently, precision diagnostic blocks are used to clarify multiple challenging situations (...) An Update of Comprehensive Evidence-Based Guidelines for Interventional Techniques in Chronic Spinal Pain - Part 2 - Guidance and Recommendations Objective: To develop evidence-based clinical practice guidelines for interventional techniques in the diagnosis and treatment of chronic spinal pain. Methodology: Systematic assessment of the literature. Evidence: I. Lumbar Spine • The evidence for accuracy of diagnostic selective nerve root blocks is limited; whereas for lumbar provocation

2013 American Society of Interventional Pain Physicians

200. Evidence-Based Guideline: Diagnosis and Treatment of Limb-Girdle and Distal Dystrophies

Alliance and Northeast ALS Consortium. Dr. Selcen has served as an editorial board member for Neuromuscular Disorders and has received funding for research from the National Institutes of Health (NIH). Dr. David reports no relevant disclosures. Dr. Raynor reports no relevant disclosures. Dr. Carter has served as the senior associate editor for Muscle & Nerve, has received honoraria from the AANEM and the Canadian Association of Physical Medicine and Rehabilitation, has received funding for research (...) Pharmaceuticals, Taro Pharmaceuticals, and Viromed (DSMB); receives funding from the NIH, the Italian Telethon (DSMB Chair), the Muscular Dystrophy Association, the Parent Project for Muscular Dystrophy, and the AAN; and receives royalties from Elsevier (for Cecil Essentials and Cecil Textbook of Medicine). 8 Dr. Amato has served as a consultant or on scientific advisory boards for MedImmune, Amgen, Biogen, DART, and Baxter; serves as an associate editor for Neurology and Muscle & Nerve; has received

2013 American Association of Neuromuscular & Electrodiagnostic Medicine

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