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81. Mesothelioma, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

82. Midline Tract Carcinoma, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

83. Papillomatosis, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

84. Head and Neck Cancer, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

85. Gastrointestinal Stromal Tumors, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

86. Esthesioneuroblastoma, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

87. Stomach (Gastric) Cancer, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

88. Colorectal Cancer, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

89. Esophageal Tumors, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

90. Chordoma, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

91. Vaginal Cancer, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

92. Unknown Primary, Childhood Carcinoma of

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

93. Heart Tumors, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

94. Bronchial Tumors, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

95. Carcinoid Tumors, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

96. Breast Cancer, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

97. Unusual Cancers of Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

98. Thyroid Tumors, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

99. Thymoma and Thymic Carcinoma, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

100. Testicular Cancer, Childhood

with nasopharyngeal carcinoma present with advanced disease (stage III/IV or T3/T4).[ , ] Population-based studies have reported that patients younger than 20 years had a higher incidence of advanced-stage disease than did adult patients.[ , ] However, less than 10% of children and adolescents with nasopharyngeal carcinoma presented with distant metastases at diagnosis.[ - ] Prognosis The overall survival of children and adolescents with nasopharyngeal carcinoma has improved over the last four decades; with state (...) cytokeratin expression.[ ] Sixty-six samples of olfactory neuroblastoma and tumor samples from other cancers, including alveolar rhabdomyosarcoma and sinonasal adenocarcinoma, were obtained from nine medical centers and analyzed by genome-wide DNA methylation profiling, copy number analysis, immunohistochemistry, and next-generation panel sequencing. Unsupervised hierarchal clustering analysis of DNA methylation data identified the following four distinct clusters:[ ] The largest cluster, which comprised

2012 PDQ - NCI's Comprehensive Cancer Database

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