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Eyelid Swelling

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161. Hypothyroidism

include: Changes to appearance such as coarse dry hair and skin and hair loss. Oedema, including swelling of the eyelids. Vocal changes such as hoarseness or deepening of the voice. Goitre. Bradycardia and diastolic hypertension. Delayed relaxation of deep tendon reflexes. Paraesthesia — due to carpal tunnel syndrome. Secondary hypothyroidism Symptoms and signs include those of primary hypothyroidism with or without those associated with: An intracranial mass such as headache, diplopia, or reduced (...) [ ; ; ; ]. Transient thyroiditis Subacute (de Quervain's) thyroiditis — painful swelling of the thyroid gland thought to be caused by viral infection [ ; ]. Postpartum thyroiditis (PPT) — PPT is the development of thyrotoxicosis, hypothyroidism, or thyrotoxicosis followed by hypothyroidism within a year of giving birth, in women who were euthyroid prior to pregnancy [ ; ; ]. Thyroid infiltrative disorders These include amyloidosis, sarcoidosis, haemochromatosis, tuberculosis, and scleroderma [ ]. Congenital

2016 NICE Clinical Knowledge Summaries

162. Hyperthyroidism

When should I suspect Graves' orbitopathy? Suspect Graves' orbitopathy if there are clinical features of: Eye irritation, photophobia, or excessive watering of the eyes. Redness of the eyes or eyelids and/or swelling or feeling of fullness in one or both upper eyelids. Change in the appearance of the eye or eyelids. Troublesome eyelid retraction (sclera is visible above the superior corneal limbus), or lid lag (delay in moving the eyelid as the eye moves downward). Proptosis (exophthalmos, eyeball (...) , and wearing eye protectors during sleep). Elevating the head of the bed (to relieve morning eyelid swelling) if needed. Provide advice on sources of information and support for people with Graves' orbitopathy, such as: The Thyroid Eye Disease Charitable Trust (website available at ), which aims to improve awareness of thyroid eye disease, runs a national telephone helpline (telephone 07469921782), has a newsletter, and runs meetings for patient education and support. The British Thyroid Foundation

2016 NICE Clinical Knowledge Summaries

163. Red eye

the CKS topic on . Ectropion (outward rotation of the eyelid margin). Entropion (inward rotation of the eyelid margin). Trichiasis (misdirection of the eyelashes towards the cornea). Child maltreatment. Although rare, suspect this if a child has retinal haemorrhages, or injury to the eye in the absence of major confirmed accidental trauma, or a known medical explanation, including birth-related causes [ ]. For more information, see the CKS topic on . Serious and potentially sight-threatening causes (...) , and systemic antimuscarinic medicines, such as tricyclics, can precipitate acute glaucoma. For more information, see the CKS topic on . Serious corneal causes. These include corneal ulcer (bacterial, viral or fungal), contact lens-related red eye and corneal foreign body. Corneal ulcer and contact lens-related red eye may start with a foreign body sensation. Usual symptoms include photophobia, blurred vision, discharge, and pain. On examination, there may be severe conjunctival injection, discharge, eyelid

2016 NICE Clinical Knowledge Summaries

164. Comparison of Minimally Invasive Strabismus Surgery (MISS) and Conventional Strabismus Surgery Using the Limbal Approach. (PubMed)

found for final alignment, binocular single vision, other visual acuities, refractive changes, or complications.This study shows that this new, small incision, minimal dissection technique is feasible. The MISS technique seems to be superior in the immediate postoperative period because there were fewer conjunctival and eyelid swelling complications. Long-term results did not differ between the two groups. [J Pediatr Ophthalmol Strabismus. 2017;54(4):208-215.].Copyright 2017, SLACK Incorporated. (...) radial cuts were made superior and inferior to the insertion of the muscle margin. Keyhole cut size was almost 1 mm less than the amount of muscle recessed or resected.There were significant differences in conjunctival redness and swelling in both groups on postoperative days 1 and 7 and week 3. However, after the third week, both groups had a similar appearance. Visual acuity was decreased at postoperative day 1 in both groups, but the difference was not significant. No significant differences were

2017 Journal of pediatric ophthalmology and strabismus

165. Continuous Intraocular Pressure Patterns in Spine Surgery

rooms for measurement errors due to inadvertent pressure on the globe while retracting the eyelids, particularly when there is significant periorbital/conjunctival swelling in the prone position. The majority of the studies recruited healthy volunteers in a simulated surgical setting so other fluctuating parameters, which can affect intraoperative IOP, cannot be measured. In the few reports where patients undergoing surgery in the prone position were studies, IOP measurements were taken at non

2017 Clinical Trials

166. Palpebral Antrax. (PubMed)

Palpebral Antrax. A 13-year-old male patient presented with a complaint of swelling of the left eye starting 3 days ago. Bullous lesion and purulent discharge were present on his left eyelids. Bacillus anthracis was shown in culture and diagnosis was confirmed. Oculocutaneous anthrax is a rare condition, but the diagnosis should be considered in patients with a painless necrotizing ulcer.

2017 Pediatric Infectious Dsease Journal

167. Methimazole-induced liver injury overshadowed by methylprednisolone pulse therapy: Case report. (PubMed)

with spontaneous retro-bulbar pain, eyelid swelling and inconstant diplopia.Thyrotoxicosis and severe GO with suspected optic nerve damage and drug induced liver injury (DILI).Intravenous methylprednisolone pulse therapy was administered to treat GO and methimazole was continued for thyrotoxicosis. Dose of methimazole was reduced after exclusion of concurrent infection and active liver disease.The GO symptoms (eyelid swelling, sight loss, proptosis, retro-bulbar pain, diplopia) markedly decreased after

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2017 Medicine

168. Orbital floor fracture repair: the endonasal approach. (PubMed)

Orbital floor fracture repair: the endonasal approach. To avoid the dangers associated with lower eyelid approaches to the orbital floor and to improve visualization, we propose an endoscopic procedure for orbital floor fracture reduction and osteosynthesis using endonasal access via the medial maxillary sinus wall. The technique of endoscopic, endonasal transantral surgery is described, together with a retrospective analysis of 17 patients who had undergone this surgical procedure (...) in the Department of Otorhinolaryngology, University of Regensburg, between July 2013 and June 2016. Fractures without infraorbital margin involvement were successfully repaired and enophthalmos and/or diplopia were corrected in all cases. The endonasal approach described here allows orbital floor fractures to be repaired without injury to the eyelid apparatus. Visualization, in particular across the orbital floor as far as the palatine process, appears to be superior to that achieved with other approaches

2017 Rhinology

169. Periocular Necrotizing Fasciitis in an Infant. (PubMed)

Periocular Necrotizing Fasciitis in an Infant. Periocular necrotizing fasciitis developed in a 12-month-old boy with swelling of both eyes and redness and a discharge from the left eye approximately 36 hours after blunt trauma. Computed tomography revealed preseptal and soft-tissue edema on the left side, but no signs of orbital involvement, orbital fractures, or drainable abscess in the anterior left lower eyelid. The inflammatory signs worsened over the next day, and there was purulent (...) discharge from the left lower eyelid and an abscess and necrosis of the lower eyelid skin. He did well following surgical debridement and treatment with intravenous antibiotics. His course highlights the difficulty in diagnosing necrotizing fasciitis and the necessity for prompt surgical debridement and empirical broad-spectrum antibiotic therapy.Copyright © 2017 Elsevier Inc. All rights reserved.

2017 Survey of Ophthalmology

170. Vehicle-Controlled, Phase 2 Clinical Trial of a Sustained-Release Dexamethasone Intracanalicular Insert in a Chronic Allergen Challenge Model. (PubMed)

, 0-4 scales) at Visit 1, and for 2 of 3 time points on subsequent visits. Subjects who met entry criteria were randomized to receive Dextenza or PV (vehicle insert). Challenges occurred over 42 days, with efficacy assessed at 14 (primary endpoint visit), 28, and 40 days postinsertion. Outcome measures included the evaluation of ocular itching, redness, tearing, chemosis, eyelid swelling, rhinorrhea, and congestion.Twenty-eight subjects completed the study in the Dextenza group and 31

2017 Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics

171. Fronto-orbitozygomatic approach: functional and cosmetic outcomes in a series of 169 patients. (PubMed)

with a focus on 4 main issues: surgical complications, functional outcome, cosmetic outcome, and patient satisfaction. The additional time needed to perform orbitotomy and orbital reconstruction was also evaluated. RESULTS The permanent postoperative complications included forehead hypesthesia (41.4%) and dysesthesia (15.3%), frontal muscle weakness (10.3%), exophthalmos (1.4%), enophthalmos (4.1%), diplopia (6.6%; 2% were related to surgical approach), and persistent periorbital and eyelid swelling (3

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2017 Journal of Neurosurgery

172. Anterior orbital leiomyoma originating from the supraorbital neurovascular bundle (PubMed)

Anterior orbital leiomyoma originating from the supraorbital neurovascular bundle To present a young female patient with left anterior orbital leiomyoma that originates from the supraorbital neurovascular bundle.A 41-year-old female patient was admitted to our clinic with a complaint of swelling of the left upper eyelid. Based on the ophthalmological and imaging assessments, the excisional biopsy with the preliminary diagnosis of dermoid cyst was planned. The histopathological

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2017 SAGE Open Medical Case Reports

173. Primary Orbital Melanoma: Presentation, Treatment, and Long-term Outcomes for 13 Patients (PubMed)

 years (mean 55.5; median 48 years) and typically gave a short history of rapidly increasing proptosis and eyelid swelling. On the basis of history, a malignant lesion was suspected in most patients and all underwent incisional biopsy, with debulking of the mass in 10 (77%) patients, and skin-sparing exenteration in 3/13 (23%). Ten patients underwent orbital radiotherapy and the survival to date ranged from 9 months to 14 years (mean 55 months; median 23 months); two patients received solely

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2017 Frontiers in oncology

174. Effects of Atorvastatin in Graves' Orbitopathy (GO)

outcome determined using a composite evaluation. A composite evaluation of GO was described previously. Possible outcomes are: improvement, worsening, no change, resulting in 3 categorical values Improvement: amelioration of two parameters in at least one eye, without deterioration of any parameters in both eyes: Deterioration: worsening in two parameters in at least one eye: All other cases are "no change" Parameters are: Eyelid swelling (improvement/worsening according to EUGOGO Atlas evaluation (...) are: Eyelid swelling (improvement/worsening according to EUGOGO Atlas evaluation) Lid aperture in mm (significant variation: 2 or more mm) Clinical activity score (CAS) (7 items: spontaneous pain, evoked pain, eyelid edema, eyelid redness, conjunctiva redness, caruncle edema, chemosis; significant change: at least 2 points) Exophthalmos in mm (significant variation 2 or more mm) Eye muscle involvement - diplopia score (Gorman score) (significant variation: disappearance or change in the degree

2017 Clinical Trials

175. Clinical Evaluation of Hylo-Dual Versus Patanol in Children With Seasonal Allergic Conjunctivitis

is the most common form of ocular allergy, with an estimated prevalence of approximately 15 to 20%. The distressing signs (redness, chemosis, eyelid swelling) and symptoms (itching, tearing, redness) of SAC may cause extreme discomfort, with a burden due to the frequency and duration of the disease more than to its seriousness. Olopatadine hydrochloride ophthalmic solution 0.1% is a topical antiallergic agent that is both an antihistamine with high affinity and selectivity for the histamine H1 receptor (...) consisting of 0.5-unit increments from 0 (normal) to 4 (total involvement). Scale based on the Efron scale. Signs of conjunctival chemosis [ Time Frame: 7 days, 14 days, 30 days, 42 days, 56 days ] Assessed by an ophthalmologist on slit-lamp examination. 9-point scale consisting of 0.5-unit increments from 0 (normal) to 4 (total involvement). Signs of eyelid swelling [ Time Frame: 7 days, 14 days, 30 days, 42 days, 56 days ] Assessed by an ophthalmologist on slit-lamp examination. 9-point scale

2017 Clinical Trials

176. A Trial to Evaluate the Efficacy of Orbital Radiotherapy in Graves' Orbitopathy

: Comparison of overall GO outcome determined using a composite evaluation [ Time Frame: 52 weeks ] A composite evaluation of GO was described previously. Improvement is defined as amelioration of two parameters in at least one eye, without deterioration of any parameters in both eyes: Deterioration is defined as worsening in two parameters in at least one eye: All other cases are defined as "no change" The parameters are: Eyelid swelling (improvement/worsening according to EUGOGO Atlas evaluation) Lid (...) GO outcome determined using a composite evaluation [ Time Frame: 26 weeks ] A composite evaluation of GO was described previously. Improvement is defined as amelioration of two parameters in at least one eye, without deterioration of any parameters in both eyes: Deterioration is defined as worsening in two parameters in at least one eye: All other cases are defined as "no change" The parameters are: Eyelid swelling (improvement/worsening according to EUGOGO Atlas evaluation) Lid aperture in mm

2017 Clinical Trials

177. Walnut Shell Glasses Moxibustion for Dry Eye Syndrome

of weeks assessed. change from baseline in VAS of eye discomfort [ Time Frame: week 4, week 16, week 28 ] Eye discomfort VAS scale: for the eye symptoms of self-assessment. Dry eye symptoms include itching, foreign body sensation, burning sensation, pain, dry, blurred vision, photophobia, eye swelling, tear Crack,ect. The overall discomfort are evaluate by VAS . Uses a 100-mm line that is labeled at each end. 0 mm represents no eye discomfort, 100 mm represents the most intolerable eye discomfort (...) of the eye, used to evaluate the stability of the tear film. In the room without air flow, 1% of the sodium fluorescein with a glass rod dipped in a little coating in the lower eyelid conjunctival sac, the patient after several times, through the slit lamp cobalt blue light wide band inspection tear film, with a stopwatch Record the last time after the completion of the first blink of an eye to open to the tear film appeared in the first randomly distributed dry spots or black lines of time, recorded

2017 Clinical Trials

178. Subconjunctival orbital fat prolapse and thyroid associated orbitopathy: a clinical association (PubMed)

Subconjunctival orbital fat prolapse and thyroid associated orbitopathy: a clinical association Thyroid associated orbitopathy (TAO) comprises a spectrum of well-recognized clinical signs including exophthalmos, eyelid retraction, soft tissue swelling, ocular misalignment, keratopathy as well as a number of less common manifestations. Subconjunctival fat prolapse is a rare clinical condition occurring typically spontaneously in elderly patients with a mean age of 65-72 years. We describe

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2017 Clinical interventions in aging

179. Primary hypertrophic osteoarthropathy due to a novel SLCO2A1 mutation masquerading as acromegaly (PubMed)

Primary hypertrophic osteoarthropathy due to a novel SLCO2A1 mutation masquerading as acromegaly A 20-year-old man with an 8-year history of progressive enlargement of his hands and feet, coarsening facial features, painful joints and thickened, oily skin was referred for investigation of acromegaly. On examination, the subject was of normal height and weight. He had markedly increased skin thickness around the forehead, eyelids and scalp with redundant skin folds. Bilateral painful knee (...) swelling was accompanied by enlargement of the extremities, and his fingers were markedly clubbed. Routine hematological, biochemical and hormonal blood tests, including GH and IGF-1 were normal. The clinical picture suggested primary hypertrophic osteoarthropathy (PHOA) rather than acromegaly and radiological studies were supportive of this, demonstrating increased subperiosteal bone formation and increased bone density and cortical thickening. There was widespread joint disease, with narrowing

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2017 Endocrinology, diabetes & metabolism case reports

180. Rosai-Dorfman Disease of the Lung Overlapping with IgG4-related Disease: The Difficulty in Its Differential Diagnosis (PubMed)

Rosai-Dorfman Disease of the Lung Overlapping with IgG4-related Disease: The Difficulty in Its Differential Diagnosis We herein report a case of Rosai-Dorfman disease (RDD) overlapping with IgG4-related disease (IgG4-RD), which presented as diffuse interstitial lung disease with a perilymphatic pattern, followed by submandibular gland and eyelid swelling. The pathological findings of the submandibular gland biopsy specimen were indicative of IgG4-RD alone. We diagnosed the patient with RDD

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2017 Internal Medicine

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