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Eyelid Swelling

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141. Tacrolimus for Malar Edema

Study Details Study Description Go to Brief Summary: Elective lower eyelid surgery is a common cosmetic procedure. Facial swelling is a common complication. Studies suggest that this facial swelling is part of a complex inflammatory process. Topical tacrolimus has long been used to treat various inflammatory skin disorders. By combining our knowledge of facial swelling and tacrolimus mechanism of action, we can hypothesize that it can be used as a treatment to prevent this post-operative swelling (...) . The purpose of this project is to apply topical tacrolimus to one of the patient's cheeks following facial surgery and compare the incidence of facial swelling to the opposite side control cheek. Condition or disease Intervention/treatment Phase Edema Face Drug: Tacrolimus Topical 0.1% Topical Ointment Drug: Polysporin Ointment Phase 2 Phase 3 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 100 participants Allocation: Randomized

2018 Clinical Trials

142. Phase III trials examining the efficacy of cetirizine ophthalmic solution 0.24% compared to vehicle for the treatment of allergic conjunctivitis in the conjunctival allergen challenge model. (PubMed)

with significant improvement in chemosis, eyelid swelling, tearing, ciliary redness, and episcleral redness, as well as nasal symptoms (rhinorrhea, nasal pruritus, ear or palatal pruritus, and nasal congestion) post-CAC. The most robust treatment differences were observed in Study 2 where more severe symptoms were required for study entry (P<0.05). No safety concerns for cetirizine ophthalmic solution 0.24% were identified.Cetirizine ophthalmic solution 0.24% was shown to be efficacious in the treatment

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2018 Clinical ophthalmology (Auckland, N.Z.)

143. A clinicopathological study on IgG4-related ophthalmic disease (PubMed)

and underwent histological evaluation. This study further investigated clinical and histopathological features of 15 patients who received systemic corticosteroid after the resection.The mean age of the patients consisting of 7 males (33%) and 14 females (67%) was 61y. Fourteen patients were diagnosed as definitive, and 2 and 5 patients were probable and possible IgG4-ROD, respectively. Eyelid swelling was an initial symptom in 11 patients (52%) who did not show systemic involvements at a diagnosis. Fifteen

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2018 International journal of ophthalmology

144. Highlighting the importance of early diagnosis in progressive multi-organ involvement of IgG4-related disease: A case report and review of literature (PubMed)

involvement for over 19 years, started with swollen eyelids, dry eye and mouth, and polydipsia and hydruria. Imaging diagnosis revealed diffuse enlargement of the parotid glands, enlargement of the head of the pancreas, pulmonary infection and interstitial lung. Serological tests showed a remarkable elevation of the serum IgG4, and cytological analysis further revealed a large amount of lymphoplasmacytic infiltration into the focal lobule, and IgG4-positive cell infiltration in bladder mucosa (...) . Therapeutically, the patient responded well to steroid therapy, and thus, she was diagnosed as IgG4-RD suspicious. This report highlights the importance of an early diagnosis in this autoimmune disease and suggests that patients with a clinically unclear cause of inflammation, swelling and refractory glands, rhinitis, pancreatitis, hypophysitis, and/or interstitial pneumonia should be considered for IgG4-RD. The plasma IgG4 level and lymphoplasmacytic infiltration may be useful indexes for screening

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2018 World journal of clinical cases

145. Mixed connective tissue disease complicated by heart failure in Ile-Ife, Nigeria: management challenges in a resource-limited economy (PubMed)

dyspnea, orthopnea, paroxysmal nocturnal dyspnea, right sided abdominal pain, leg swellings, a one year history of recurrent fever, Raynaud's phenomenon, small joint swellings and deformities with pain in both hands.On examination there was microstomia, tethered forehead and lower eyelid skin, tender swelling of the interphalangeal joints and arthritis mutilans. Laboratory findings showed estimated glomerular filtration rate <60 mL/kg/min/1.73 m2, U1RNP antibody levels were eight times upper limit

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2018 International medical case reports journal

146. Primary lacrimal sac diffuse large B-cell lymphoma in a child. (PubMed)

Primary lacrimal sac diffuse large B-cell lymphoma in a child. We report the case of a 13-year-old boy who presented with a 2-month history of left eyelid swelling, ecchymosis, and epiphora. Magnetic resonance imaging revealed a lobulated lesion in the region of the left lacrimal sac extending to the left nasolacrimal duct. Biopsy revealed diffuse large B-cell lymphoma of the lacrimal sac. Chemotherapy was initiated, consisting of rituximab, methotrexate, cytarabine, doxorubicin

2018 JAAPOS - Journal of the American Association for Pediatric Ophthalmology and Strabismus

147. Post-traumatic right carotid-cavernous fistula resulting in symptoms in the contralateral eye: a case report and literature review. (PubMed)

Post-traumatic right carotid-cavernous fistula resulting in symptoms in the contralateral eye: a case report and literature review. To report a case of a carotid-cavernous fistula (CCF) that occurred after a motor vehicle accident and review the uniqueness of this case and the main confusing points for the diagnosis of such cases.A 22-year-old man complained of left eyelid swelling, eye redness, visual decrease and occasional headache after motor vehicle accident 4 months prior during which he

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2018 BMC Ophthalmology

148. Histiocytic lesions of the orbit: A study of 9 cases (PubMed)

Histiocytic lesions of the orbit: A study of 9 cases To describe the clinical presentation, treatment, and outcome of patients with histiocytic lesions of the orbit.Retrospective study of 9 patients treated and followed up between October 2001 and January 2018.Eight patients in our series were males and one patient was female. The mean age at presentation was 16.8 years (range, 1 to 42 years). All patients had unilateral disease. The most common presenting complaint was upper eyelid swelling

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2018 Saudi Journal of Ophthalmology

149. Orbital cellulitis with choroidal detachment following strabismus surgery in an adult. (PubMed)

Orbital cellulitis with choroidal detachment following strabismus surgery in an adult. We report the case of a 76-year-old man who presented with left eye pain, eyelid swelling, and restricted extraocular motility 3 days after strabismus surgery. Computed tomography of the orbits did not show drainable abscesses, but magnetic resonance imaging on postoperative day 9 showed choroidal detachment with retrobulbar abscess and dural enhancement despite broad-spectrum intravenous antibiotic use

2018 JAAPOS - Journal of the American Association for Pediatric Ophthalmology and Strabismus

150. Surgical correction of residual facial deformity following conservative excision of a giant maxillary ossifying fibroma: A case report. (PubMed)

Surgical correction of residual facial deformity following conservative excision of a giant maxillary ossifying fibroma: A case report. Ossifying fibroma (OF) is a benign fibro-osseous lesion that can develop in the oral and maxillofacial region. OF is more common in females and has a marked predilection for the mandible, occurring rarely in the maxilla. Lesions grow slowly and are usually asymptomatic until growth produces an obvious swelling, pain, paresthesia, and facial deformity. With low (...) conservative excision via the Weber-Ferguson approach and followed up every 6 months. Facial deformity correction was performed 2 years postoperatively and right lower eyelid ectropion correction 3 years after the primary excision.The ectropion deformity in the right lower eyelid improved dramatically with a better facial appearance and no obvious swelling.Treatment programs for OF should be individualized based on the size, growth rate, invasion, and interference with facial function and esthetics

2018 Medicine

151. A case report on complete cure of recurrent primary canaliculitis by 4-snip punctoplasty and canalicular curettage. (PubMed)

of epiphora, discharge, eyelid flare up, and swelling near the inferior lacrimal punctum in the left eye, which initially presented 6 months earlier.Based on the aforementioned symptoms, the patient was initially diagnosed with bacterial conjunctivitis at a local ophthalmologic clinic and used antibiotic eye drops for 6 months. However, her symptoms did not improve and they worsened at 2 weeks prior to admission. She was subsequently diagnosed with chronic dacryocystitis and referred to our hospital (...) for surgical treatment. Slit lamp examination results showed conjunctival congestion in the inner corner of the left eye, along with eyelid flare up, swelling near the inferior lacrimal punctum, and yellowish discharge and concretion from the lacrimal punctal orifice. Furthermore, punctal regurgitation was not observed in the lacrimal sac compression test. Thus, the patient was diagnosed with primary canaliculitis on the basis of her clinical symptoms and laboratory findings.Based on the diagnosis

2018 Medicine

152. Childhood Vascular Tumors Treatment (PDQ®): Patient Version

: Steroids are made naturally in the body. They can also be made in a laboratory and used as drugs. help shrink some vascular tumors. , such as and , are used to treat infantile hemangioma. (NSAIDs): NSAIDs are commonly used to decrease , swelling, pain, and redness. Examples of NSAIDs are , , and . In the treatment of vascular tumors, NSAIDs can increase the flow of blood through the tumors and decrease the chance that an unwanted will form. Antifibrinolytic therapy: These drugs help the blood clot (...) vision problems or blindness. Infantile hemangiomas can occur in the (a that lines the inner surface of the eyelid and covers the front part of the eye). These hemangiomas may be linked with other of the eye. It is important that children with an ophthalmic hemangioma are examined by an . Signs and Symptoms Infantile hemangiomas may cause any of the following signs and . Check with your child’s doctor if your child has any of the following: Skin lesions: An area of spidery veins or lightened

2016 PDQ - NCI's Comprehensive Cancer Database

153. Childhood Vascular Tumors Treatment (PDQ®): Health Professional Version

of the upper medial eyelid but any hemangioma around the eye that is large enough can obstruct the visual axis. The clinician should be aware of subcutaneous periocular hemangiomas, as these lesions can extend into the orbit, causing exophthalmos or globe displacement with only limited cutaneous manifestations. Issues with these lesions include astigmatism from direct pressure of the growing hemangioma, ptosis, proptosis, and strabismus. One of the leading causes of preventable blindness in children (...) Clinical presentation Epithelioid hemangiomas are benign lesions that usually occur in the skin and subcutis but can occur in other areas such as the bone, with focal and multifocal lesions.[ , ] Epithelioid hemangiomas may be a reactive process, as they can be associated with local trauma and can develop in pregnancy. Patients usually present with local swelling and pain at the involved site. In the bone, they present as well-defined lytic lesions that involve the metaphysis and diaphysis of long

2016 PDQ - NCI's Comprehensive Cancer Database

154. Diabetic Retinopathy Guidelines

Retinopathy Specific Non-Specific Retinal Detachment Cataract Rubeosis Iridis Cataract Glaucoma Retinal Vein Occlusion/Optic Disc Swelling Optic Neuropathy 1.3.1 Non-specific ocular disease associations Cataract Cataract is defined as opacification of the lens and is common in older age populations. Age-related cataract occurs earlier in patients with diabetes. 10 Glaucoma Glaucoma is defined as loss of vision due to raised intraocular pressure and occurs in two forms: primary or secondary (...) / Optic disc swelling Patients with diabetes are at higher risk of developing optic nerve disease due to vascular occlusion, which is distinct from diabetes-specific optic neuropathy (see below) and usually occurs in older patients with Type 2 diabetes and hypertension. This may be a form of ischaemic optic neuropathy. 1.3.2 Specific complications Retinal Detachment Retinal detachment is caused by the accumulation of fluid between the neural retina and the retinal pigment epithelium and in non

2012 Royal College of Ophthalmologists

156. Late Effects of Treatment for Childhood Cancer (PDQ®): Patient Version

). . Chest pain or heart attack. or one or more . disease. Possible signs and symptoms of heart and blood vessel late effects include trouble breathing and chest pain. These and other and may be caused by heart and blood vessel late effects or by other : Trouble breathing, especially when lying down. Heartbeat that is too slow, too fast, or different from the heart's normal rhythm. Chest pain. Swelling of the feet, ankles, legs, or . When exposed to cold or having strong emotions, the fingers, toes, ears (...) of extra after having many . Possible signs and symptoms of liver and bile duct late effects include abdominal pain and jaundice. These and other signs and symptoms may be caused by liver and bile duct late effects or by other conditions: Weight gain or weight loss. Swelling of the abdomen. Nausea and vomiting. Pain in the abdomen. Pain may occur near the ribs, often on the right side, or after eating a fatty meal. (yellowing of the skin and whites of the eyes). Light-colored bowel movements. Dark

2016 PDQ - NCI's Comprehensive Cancer Database

159. Olopatadine for the Treatment of Allergic Conjunctivitis: A Review of the Clinical Efficacy, Safety, and Cost-Effectiveness

that allergic eye disease affects more than 20% of the population in industrialized countries and its prevalence is increasing worldwide. 2 Seasonal allergic conjunctivitis (SAC) and perennial allergic conjunctivitis (PAC) are the most prevalent forms of ocular allergy. 3 The signs and symptoms of allergic conjunctivitis include itching, redness, tearing, eyelid swelling and chemosis. 4 Usually, allergic conjunctivitis does not pose a risk for the individual’s vision but is an important health problem (...) treatments with olopatadine and ketotifen for reduction in signs and symptoms of allergic conjunctivitis. One study 13 found no significant differences between olopatadine and ketotifen with respect to mean scores for tearing, itching, redness, eyelid swelling or chemosis at any time point. Two studies 10,15 showed that compared to ketotifen, olopatadine had a significantly greater effect in controlling itching and hyperemia. Compared to ketotifen, olopatadine demonstrated a greater effect in controlling

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

160. Metastatic tumors to the eyelid: report of 20 cases and review of the literature. (PubMed)

, and salivary gland carcinoma (1 [5%] each). Eyelid metastasis was the first sign of systemic cancer in 3 patients (15%). The most common clinical finding at the initial examination was a solitary nodule in 12 patients (60%), a flat pigmented lesion and diffuse eyelid swelling in 3 patients each (15%), and multiple nodules and epiphora in 1 patient (5%) each. Ten patients (50%) had concomitant ocular site metastasis. Primary treatment included excision alone in 6 patients (30%), external beam radiotherapy (...) Metastatic tumors to the eyelid: report of 20 cases and review of the literature. To determine the primary sites, clinical features, treatment, and outcome of 20 patients with cancer metastatic to the eyelids.Retrospective review of medical records.The primary tumors included skin melanoma (4 [20%]), uveal melanoma (4 [20%]), breast carcinoma and conjunctival melanoma (3 [15%] each), renal cell carcinoma (2 [10%]), and medullary thyroid carcinoma, prostate carcinoma, lung carcinoma

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2009 Archives of Ophthalmology

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