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Eye Pain

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1. Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults. (PubMed)

Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults. Hyaluronidase has been used over many decades as an adjunct to local anaesthetic solution to improve the speed of onset of eye blocks and to provide better akinesia and analgesia. With the evolution of modern eye surgery techniques, fast onset and akinesia are not essential requirements anymore. The assumption that the addition of hyaluronidase to local anaesthetic injections confers (...) in any of the studies. No study reported on the cost of hyaluronidase in the context of eye surgery.The effects of adding hyaluronidase to local anaesthetic fluid on pain outcomes in people undergoing eye surgery are uncertain due to the low quality of evidence available. A well designed RCT is required to address inconsistency and imprecision among the studies and to determine the benefit of hyaluronidase to improve analgesia during eye surgery. Participant and surgical satisfaction is higher

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2018 Cochrane

2. CRACKCast E022 – Red and Painful Eye

CRACKCast E022 – Red and Painful Eye CRACKCast E022 - Red and Painful Eye - CanadiEM CRACKCast E022 – Red and Painful Eye In , by Adam Thomas January 12, 2017 This episode of CRACKCast cover’s Rosen’s Chapter 22, Red and Painful Eye 1 . The red and painful eye can be a vision-threatening medical emergency and should be treated urgently to avoid long-term sequelae. Shownotes – Rosen’s in Perspective: Review your eye anatomy in Rosen’s Eye anatomy review. From Rosen’s. Recap the key components (...) Miotic pupil Lens cataracts Blood in the vitreous Retinal detachment Bedside testing: Fluorescein testing – uptake occurs only in damaged corneal tissue. Under slit-lamp Cobalt blue light: Have the patient blink, if there is uncertainty regarding the uptake of fluorescein on the cornea Local anesthetic testing: If the anesthetic abolishes the patient’s eye pain – the pain is of corneal origin If the pain is mildly relieved – probable conjunctival origin Seidel’s sign: Use with the suspicion of ocular

2017 CandiEM

3. Value of considering psychological strengths in patients with eye pain (PubMed)

Value of considering psychological strengths in patients with eye pain To characterize the possibility of strength intervention to improve eye-related quality of life and satisfaction with life of a patient who experienced eye pain and dissatisfaction with the outcomes of ocular surgery.A young female patient who underwent LASIK surgery and experienced dissatisfaction with the outcome claimed that she had eye pain and had lost her strengths and self-confidence, having lower quality of life

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2018 American journal of ophthalmology case reports

4. Eye Pain and Dry Eye in Patients with Fibromyalgia. (PubMed)

Eye Pain and Dry Eye in Patients with Fibromyalgia. The aim of this study was to examine visual function and eye symptoms in fibromyalgia patients, with a particular focus on dry eye syndrome and eye pain.A tertiary care center-based cross-sectional study was carried out in chronic musculoskeletal pain patients diagnosed with fibromyalgia. Chronic musculoskeletal pain patients without fibromyalgia were enrolled as a comparison group. Self-reported eye pain was investigated with the McGill pain (...) questionnaire and the numeric rating scale. In addition, we assessed corrected visual acuity, vision-related quality of life, and self-reported dry eye syndrome.A total of 90 musculoskeletal pain patients were included, with 66 patients fulfilling American College of Rheumatology 1990 criteria for fibromyalgia. Sixty-seven percent (95% confidence interval [CI] = 56%-78%) of the fibromyalgia patients reported eye pain, and 62% (95% CI = 43%-81%) of those were without fibromyalgia diagnosis. Sixty-seven

2018 Pain Medicine

5. Comparing the effect of eye movement desensitization and reprocessing (EMDR) with guided imagery on pain severity in patients with rheumatoid arthritis (PubMed)

Comparing the effect of eye movement desensitization and reprocessing (EMDR) with guided imagery on pain severity in patients with rheumatoid arthritis Previous studies reported the reduction of pain following eye movement desensitization and reprocessing (EMDR) and guided imagery; however, the effectiveness of these modalities was not compared. The current study aimed to compare the effects of EMDR and guided imagery on pain severity in patients with rheumatoid arthritis.In this randomized (...) controlled trial, 75 patients were selected using non-random method, and then allocated into two intervention groups and one control group. Interventions were conducted individually in six consecutive sessions for the intervention groups. The Rheumatoid Arthritis Pain Scale was used for data collection before and after the interventions. Collected data were analyzed with descriptive and inferential statistics in SPSS. Significance level was considered at P<0.05.The post-intervention mean scores

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2018 EvidenceUpdates

6. Keeping an eye on pain: investigating visual attention biases in individuals with chronic pain using eye-tracking methodology (PubMed)

Keeping an eye on pain: investigating visual attention biases in individuals with chronic pain using eye-tracking methodology Attentional biases to painful stimuli are evident in individuals with chronic pain, although the directional tendency of these biases (ie, toward or away from threat-related stimuli) remains unclear. This study used eye-tracking technology, a measure of visual attention, to evaluate the attentional patterns of individuals with and without chronic pain during exposure (...) to injury-related and neutral pictures. Individuals with (N=51) and without chronic pain (N=62) completed a dot-probe task using injury-related and neutral pictures while their eye movements were recorded. Mixed-design analysis of variance evaluated the interaction between group (chronic pain, pain-free) and picture type (injury-related, neutral). Reaction time results showed that regardless of chronic pain status, participants responded faster to trials with neutral stimuli in comparison to trials

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2016 Journal of pain research

7. Eye-movement behaviours when viewing real-world pain-related images. (PubMed)

Eye-movement behaviours when viewing real-world pain-related images. Pain-related cues are evolutionarily primed to capture attention, although evidence of attentional biases towards pain-related information is mixed in healthy individuals. The present study explores whether healthy individuals show significantly different eye-movement behaviours when viewing real-world pain-related scenes compared to neutral scenes. The effect of manipulating via written information the threat value (...) of the pain-related scenes on eye-movement behaviours was also assessed.Participants were randomized to threatening (n = 28) and non-threatening (n = 27) information conditions. All completed a free-viewing task with real-world pain-related and neutral images while their eye movements were recorded.Participants made significantly fewer fixations of significantly longer duration when viewing pain-related images compared to neutral images. No significant differences were found between threatening and non

2019 European Journal of Pain

8. Evidence of central sensitisation in those with dry eye symptoms and neuropathic-like ocular pain complaints: incomplete response to topical anaesthesia and generalised heightened sensitivity to evoked pain. (PubMed)

Evidence of central sensitisation in those with dry eye symptoms and neuropathic-like ocular pain complaints: incomplete response to topical anaesthesia and generalised heightened sensitivity to evoked pain. To evaluate how closely neuropathic-like ocular pain (NOP) symptoms align with a metric of central sensitisation (ie, the presence of persistent ocular pain after topical anaesthetic placement) in individuals with dry eye (DE) symptoms.Cross-sectional study of 224 individuals with DE (...) symptoms seen in the Miami Veterans Affairs eye clinic. An evaluation was performed consisting of questionnaires regarding DE symptoms, NOP descriptors and evoked pain sensitivity testing on the forehead and forearm, followed by a comprehensive ocular surface examination including corneal mechanical sensitivity testing. Subsequent analyses were performed to examine for differences between those with and without ocular pain after topical anaesthetic placement.The mean age was 62 years with 91% being men

2017 British Journal of Ophthalmology

9. Acute or Recurrent Abdominal Pain: The Eyes Can Only See What the Mind Knows! (PubMed)

Acute or Recurrent Abdominal Pain: The Eyes Can Only See What the Mind Knows! 28868448 2018 11 13 2341-4545 23 3 2016 May-Jun GE Portuguese journal of gastroenterology GE Port J Gastroenterol Acute or Recurrent Abdominal Pain: The Eyes Can Only See What the Mind Knows! 130-131 10.1016/j.jpge.2016.01.007 Zullo Angelo A Internal Medicine and Gastroenterology Unit, 'Nuovo Regina Margherita' Hospital, Rome, Italy. Bruzzese Vincenzo V Internal Medicine and Gastroenterology Unit, 'Nuovo Regina

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2016 GE Portuguese journal of gastroenterology

10. Improvement of Erection Related Incision Pain in Circumcision Patients using Interrupted Rapid Eye Movement Sleep: A Randomized Controlled Study. (PubMed)

Improvement of Erection Related Incision Pain in Circumcision Patients using Interrupted Rapid Eye Movement Sleep: A Randomized Controlled Study. Postoperative pain from male circumcision (MC) is common especially in the sleep-related erection period. This study aims to explore the effect of interrupted rapid eye movement (IREM) sleep on relieving SRE-related incision pain and the improvement of other clinical outcomes.This simple randomized controlled study was conducted between May (...) and November 2016. Approval was obtained from the local ethical committee on 5 May 2016. Ninety participants who underwent male circumcision were divided into the interrupted rapid eye movement sleep group and the control group. The times and the cumulative time of erection-related moderate and severe pain in minutes at night for 3 days after the operation were observed and compared. We also compared the condition of the incision swelling and healing.Sleep time at night was used to evaluate the safety

2018 Urology journal

11. Effects of Covering the Eyes versus Playing Intrauterine Sounds on Premature Infants' Pain and Physiological Parameters during Venipuncture. (PubMed)

Effects of Covering the Eyes versus Playing Intrauterine Sounds on Premature Infants' Pain and Physiological Parameters during Venipuncture. There is a need to assess the impact of initiatives to reduce exposure to environmental light and sound in preterm infants undergoing painful interventions in neonatal intensive care units.In this study, we aimed to identify the effect of covering the eyes and playing the intrauterine ambient sounds on premature infants' pain and physiological parameters (...) during venipuncture.This was a randomized controlled trial. Ninety-four preterm infants were randomly divided into three groups: intrauterine sounds (n=32), covered eyes (n=32), and control (n=30) groups. Data were collected on the Preterm Infant Information Form, Preterm Infant Follow-up Form, and Neonatal Infant Pain Scale (NIPS), used to assess pain.A significant difference was found between the intervention and control groups' NIPS score after venipuncture, which was primarily due to covered eyes

2018 Journal of pediatric nursing

12. Efficacy of Care for Blind Painful Eyes. (PubMed)

Efficacy of Care for Blind Painful Eyes. Pain relief for a blind painful eye often follows an escalating paradigm of interventions. This study compares the efficacy of common interventions.A retrospective chart review of blind painful eye cases was conducted at a single tertiary institution from April 2012 to December 2016. Demographics, etiology, treatment, and pain level were assessed.Among 99 blind painful eyes, 96 eyes initially received medical therapy (topical steroids, cycloplegics (...) , and/or hypotensives), with pain relief in 39% of eyes. Minimally invasive interventions (laser cyclophotocoagulation, retrobulbar injection, or corneal electrocautery) were performed 41 times in 36 eyes, 34 of which had failed medical therapy, and led to pain relief in 75% of eyes. Evisceration or enucleation was performed in 28 eyes, and long-term pain relief was achieved in 100% of eyes. Surgery allowed discontinuation of oral analgesics in 100% of cases versus 20% for minimally invasive therapy (p = 0.005

2018 Ophthalmic plastic and reconstructive surgery

13. A Comparison of Breast Milk and Sucrose in Reducing Neonatal Pain During Eye Exam for Retinopathy of Prematurity. (PubMed)

A Comparison of Breast Milk and Sucrose in Reducing Neonatal Pain During Eye Exam for Retinopathy of Prematurity. This double-blind randomized controlled experimental study aimed to determine the effects of breast milk and sucrose in reducing pain in preterm infants during retinopathy of prematurity (ROP) examination.This study was conducted with 60 preterm infants (breast milk group = 20, sucrose group = 20, and control/distilled water group = 20) meeting the inclusion criteria. The data were (...) collected with the use of an Infant Evaluation Form, Procedure Monitoring Form, and Premature Infant Pain Profile (PIPP). The preterm infants were provided with 1 mL of breast milk, sucrose, and distilled water before the ROP examination. The pain level in preterm infants was measured by the PIPP 5 minutes before, during, and 5 minutes after the ROP examination. The ROP examinations were video recorded, and videos were evaluated by three observers blinded to the study.No significant difference

2018 Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine

14. Effects of Pranoprofen on Aqueous Humor Monocyte Chemoattractant Protein-1 Level and Pain Relief During Second-Eye Cataract Surgery (PubMed)

Effects of Pranoprofen on Aqueous Humor Monocyte Chemoattractant Protein-1 Level and Pain Relief During Second-Eye Cataract Surgery The aim of our present study is to evaluate the efficacy of pranoprofen eye drops as pain relief during sequential second-eye cataract surgery and to investigate the possible mechanism. Seventy-six patients scheduled for bilateral sequential cataract surgery were randomly assigned to two groups: (1) treatment group (administered pranoprofen eye drops), or (2 (...) ) control group (administered artificial tears). Preoperative anxiety and intraoperative pain were assessed. Monocyte chemoattractant protein 1 (MCP-1) in the aqueous humor was measured with a suspension cytokine array. An extracapsular lens extraction model was established in the Wistar rat and the MCP-1 concentrations were measured with an enzyme-linked immunosorbent assay. We found that in the control group, the pain scores were significantly higher during second-eye surgery than during first-eye

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2018 Frontiers in pharmacology

15. Is Eye Color Related to Dental Injection Pain? A Prospective, Randomized, Single-blind Study. (PubMed)

Is Eye Color Related to Dental Injection Pain? A Prospective, Randomized, Single-blind Study. Recent studies have investigated the relationship between pain perception and specific phenotypes such as red hair color and various eye colors. Further investigations into biomarkers as they relate to pain could be useful in understanding underlying genetic components involved in these pathways. Additionally, it would be clinically useful to determine if a patient would be more likely to experience (...) pain during dental treatment based on eye color. The purpose of this study was to investigate a link between eye color and perceived injection pain in healthy, asymptomatic white women.Three hundred healthy, adult, white female patients were included, 133 with dark eyes and 167 with light eyes. Dental anxiety was assessed with the Corah Dental Anxiety Scale. Subjects with their eye color masked by dark glasses received a right maxillary lateral incisor infiltration of 1 cartridge of 2% lidocaine

2018 Journal of Endodontics

16. Effects of Higher versus Lower Threat Contexts on Pain-Related Attention Biases: An Eye-Tracking Study. (PubMed)

Effects of Higher versus Lower Threat Contexts on Pain-Related Attention Biases: An Eye-Tracking Study. Threat is hypothesized to affect the degree to which pain captures attention but little is known about its impact on dynamic courses of attention towards pain. In this eye-tracking study, we evaluated pain-related visual attention biases during image pair presentations in comparatively lower versus higher threat conditions.Gaze biases of healthy adults (47 women, 35 men) were assessed during (...) image presentation phases standardized across (1) a modified visual dot-probe task featuring painful-neutral (pain) and neutral-neutral contrast (neutral) image pair blocks (lower threat context); and (2) an impending pain task wherein the same image pair blocks, respectively, cued potentially painful postoffset somatosensory stimuli (higher threat context) and its absence.Across tasks, participants were more often oriented towards, gazed longer at, and fixated more times on pain images in pain

2018 European Journal of Pain

17. Perioperative Stress and Pain Perception of Second Eye Cataract Surgery

Perioperative Stress and Pain Perception of Second Eye Cataract Surgery Perioperative Stress and Pain Perception of Second Eye Cataract Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Perioperative (...) Stress and Pain Perception of Second Eye Cataract Surgery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03749759 Recruitment Status : Recruiting First Posted : November 21, 2018 Last Update Posted : February 27, 2019 See

2018 Clinical Trials

18. Assessment of synchronous neural activities revealed by regional homogeneity in individuals with acute eye pain: a resting-state functional magnetic resonance imaging study (PubMed)

Assessment of synchronous neural activities revealed by regional homogeneity in individuals with acute eye pain: a resting-state functional magnetic resonance imaging study Previous neuroimaging studies have demonstrated that pain-related diseases are associated with brain function and anatomical abnormalities, whereas altered synchronous neural activity in acute eye pain (EP) patients has not been investigated. The purpose of this study was to explore whether or not synchronous neural activity (...) /postcentral gyrus (Brodmann area [BA]3/4), right precentral/postcentral gyrus (BA3/4), and left middle frontal gyrus (BA6). In contrast, higher ReHo values in acute EP patients were observed in the left superior frontal gyrus (BA11), right inferior parietal lobule (BA39/40), and left precuneus (BA7). However, no relationship was found between the mean ReHo signal values of the different areas and clinical manifestations, which included both the duration and degree of pain in EP patients.Our study

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2018 Journal of pain research

19. Adult Male with Traumatic Eye Pain and Swelling (PubMed)

Adult Male with Traumatic Eye Pain and Swelling 29849272 2018 11 14 2474-252X 2 2 2018 May Clinical practice and cases in emergency medicine Clin Pract Cases Emerg Med Adult Male with Traumatic Eye Pain and Swelling. 169-170 10.5811/cpcem.2018.2.36857 Leshner Marc M Lewis Katz School of Medicine at Temple University, Department of Emergency Medicine, Philadelphia, Pennsylvania. Gibbons Ryan R Lewis Katz School of Medicine at Temple University, Department of Emergency Medicine, Philadelphia

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2018 Clinical Practice and Cases in Emergency Medicine

20. The Relationship Between Ocular Itch, Ocular Pain, and Dry Eye Symptoms (An American Ophthalmological Society Thesis) (PubMed)

The Relationship Between Ocular Itch, Ocular Pain, and Dry Eye Symptoms (An American Ophthalmological Society Thesis) To evaluate associations between sensations of ocular itch and dry eye (DE) symptoms, including ocular pain, and DE signs.A cross-sectional study of 324 patients seen in the Miami Veterans Affairs eye clinic was performed. The evaluation consisted of questionnaires regarding ocular itch, DE symptoms, descriptors of neuropathic-like ocular pain (NOP), and evoked pain sensitivity (...) -ocular pain and demonstrate abnormal somatosensory testing in the form of increased sensitivity to evoked pain at a site remote from the eye, consistent with generalized hypersensitivity.

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2018 Transactions of the American Ophthalmological Society

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