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Eye Pain

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1. Modification of the Neuropathic Pain Symptom Inventory for use in eye pain (NPSI-Eye). (Abstract)

Modification of the Neuropathic Pain Symptom Inventory for use in eye pain (NPSI-Eye). Chronic eye pain, which has previously been assumed to be due to ocular surface abnormalities (ie, "dry eye [DE] disease"), has recently garnered attention as a potential indicator of neuropathic ocular pain in some patients. The purpose of this study was to evaluate the psychometric properties of a modified version of the Neuropathic Pain Symptom Inventory in individuals with eye pain (NPSI-Eye). Enrolled (...) participants (n = 397) completed the NPSI-Eye, general pain severity questionnaires, DE symptom report, and psychological health indices. Participants also underwent mechanical pain sensitivity testing of the cornea, tear film assessment, and evaluation of the efficacy of anesthetic eye drops to relieve pain. Short-term test-retest reliability of the NPSI-Eye was excellent (intraclass correlation coefficient = 0.98, P < 0.001). Correlations between the NPSI-Eye and indicators of general eye pain were ≥0.65

2019 Pain

2. CRACKCast E022 – Red and Painful Eye

Miotic pupil Lens cataracts Blood in the vitreous Retinal detachment Bedside testing: Fluorescein testing – uptake occurs only in damaged corneal tissue. Under slit-lamp Cobalt blue light: Have the patient blink, if there is uncertainty regarding the uptake of fluorescein on the cornea Local anesthetic testing: If the anesthetic abolishes the patient’s eye pain – the pain is of corneal origin If the pain is mildly relieved – probable conjunctival origin Seidel’s sign: Use with the suspicion of ocular (...) CRACKCast E022 – Red and Painful Eye CRACKCast E022 - Red and Painful Eye - CanadiEM CRACKCast E022 – Red and Painful Eye In , by Adam Thomas January 12, 2017 This episode of CRACKCast cover’s Rosen’s Chapter 22, Red and Painful Eye 1 . The red and painful eye can be a vision-threatening medical emergency and should be treated urgently to avoid long-term sequelae. Shownotes – Rosen’s in Perspective: Review your eye anatomy in Rosen’s Eye anatomy review. From Rosen’s. Recap the key components

2017 CandiEM

3. Resolution of self-injurious behavior in a nonverbal and developmentally delayed patient after surgical treatment of a blind painful eye. Full Text available with Trip Pro

Resolution of self-injurious behavior in a nonverbal and developmentally delayed patient after surgical treatment of a blind painful eye. Changes in behavioral patterns can be the only indication of the presence of pain in nonverbal patients. Phthisis bulbi results in shrinking, disorganization, and sometimes severe inflammation of the ocular globe and can occur after eye injury or multiple eye surgeries. Chronic tearing, frequent eye rubbing, and self-injurious behavior focused around the eye (...) and periocular region may indicate ocular discomfort in nonverbal patients. In eyes that become painful and refractory to medical treatment, ocular evisceration or enucleation can provide immediate pain relief. An ocular prosthesis provides excellent cosmetic results to restore normal facial appearance after surgery.

2019 American journal of ophthalmology case reports Controlled trial quality: uncertain

4. Value of considering psychological strengths in patients with eye pain Full Text available with Trip Pro

Value of considering psychological strengths in patients with eye pain To characterize the possibility of strength intervention to improve eye-related quality of life and satisfaction with life of a patient who experienced eye pain and dissatisfaction with the outcomes of ocular surgery.A young female patient who underwent LASIK surgery and experienced dissatisfaction with the outcome claimed that she had eye pain and had lost her strengths and self-confidence, having lower quality of life (...) despite the successful surgery. We performed strength intervention in an attempt to improve her psychological condition. After the intervention, her quality of life and satisfaction with life improved, although her near vision remained unchanged.This case report emphasized the importance of considering positive psychological aspects when dealing with patients who are dissatisfied with the outcomes of ocular surgery. Ophthalmologists should proactively consider their patients' psychological strengths

2018 American journal of ophthalmology case reports

5. Visual attention to pain cues for impending touch versus impending pain: An eye tracking study. (Abstract)

Visual attention to pain cues for impending touch versus impending pain: An eye tracking study. In this eye tracking study, we evaluated pain-related biases in orienting and maintenance of gaze within impending touch versus impending pain tasks and examined features of pain resilience as individual difference influences on potential biases.Gaze preferences of healthy adults (25 women and 39 men) were assessed during standardized pain-neutral (P-N) image pair presentations (2,000 ms (...) ) of an impending touch task versus an impending pain task whereby image pair offsets were followed by potential non-painful touch and potential pain stimulation, respectively.Within each task, participants were significantly more likely to fixate first upon pain images in P-N pairs and maintain gaze on these images for longer overall durations during trials. Between task comparisons indicated pain-related biases in orienting and maintenance were significantly stronger when image pairs signalled potential pain

2019 European Journal of Pain

6. Pain-related gaze biases and later functioning among adults with chronic pain: a longitudinal eye-tracking study. (Abstract)

Pain-related gaze biases and later functioning among adults with chronic pain: a longitudinal eye-tracking study. In previous studies that examined the impact of attention biases (ABs) on later pain outcomes, reaction times (RTs) in response to brief stimulus presentations had been used as measures of attention. Consequently, little is known about effects of ABs assessed during presentations of cues or biases in prolonged attention towards pain stimuli as influences on subsequent functioning (...) . To address these gaps, 89 adults with chronic pain (68 women, 21 men) engaged in a baseline dot-probe task in which visual attention was tracked during injury-neutral (I-N) image pair presentations as well as a 6-month follow-up reassessing pain intensity and interference from pain. Neither RTs to probes after image pair offsets nor biases in initial orienting of gaze towards injury images predicted follow-up outcomes. However, participants who gazed at injury images for longer durations during I-N

2019 Pain

7. Dry eye: sometimes associated with antimuscarinic drugs

. These drugs also reduce tear production and can therefore cause ocular dryness, which is often reversible when the medication is discontinued. The symptoms of dry eye disease range from discomfort to pain all the way to corneal lesions that can cause scars and impaired vision. According to a report by the French Ophthalmological Society, dry eye accounts for some 25% of consultations with ophthalmologists. Medications with antimuscarinic effects are commonly used in many different situations. With most (...) Dry eye: sometimes associated with antimuscarinic drugs Prescrire IN ENGLISH - Spotlight ''Dry eye: sometimes associated with antimuscarinic drugs'', 1 May 2020 {1} {1} {1} | | > > > Dry eye: sometimes associated with antimuscarinic drugs Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Dry eye: sometimes associated with antimuscarinic drugs When

2020 Prescrire

8. Comparing the effect of eye movement desensitization and reprocessing (EMDR) with guided imagery on pain severity in patients with rheumatoid arthritis Full Text available with Trip Pro

Comparing the effect of eye movement desensitization and reprocessing (EMDR) with guided imagery on pain severity in patients with rheumatoid arthritis Previous studies reported the reduction of pain following eye movement desensitization and reprocessing (EMDR) and guided imagery; however, the effectiveness of these modalities was not compared. The current study aimed to compare the effects of EMDR and guided imagery on pain severity in patients with rheumatoid arthritis.In this randomized (...) controlled trial, 75 patients were selected using non-random method, and then allocated into two intervention groups and one control group. Interventions were conducted individually in six consecutive sessions for the intervention groups. The Rheumatoid Arthritis Pain Scale was used for data collection before and after the interventions. Collected data were analyzed with descriptive and inferential statistics in SPSS. Significance level was considered at P<0.05.The post-intervention mean scores

2018 EvidenceUpdates Controlled trial quality: uncertain

9. Perspective-taking influences attentional deployment towards facial expressions of pain: an eye-tracking study. (Abstract)

Perspective-taking influences attentional deployment towards facial expressions of pain: an eye-tracking study. Empathetic perspective-taking (PT) may be critical in modulating attention and associated responses to another's pain. However, the differential effects of imagining oneself to be in the pain sufferer's situation ("Self-perspective") or imagining the negative impacts on the pain sufferer's experience ("Other-perspective") on attention have not been studied. The effects of observer PT (...) (Self vs Other) and level of facial pain expressiveness (FPE) upon attention to another person's pain was investigated. Fifty-two adults were assigned to 1 of 3 PT conditions; they were instructed to view pairs of pain expressions and neutral faces and either (1) consider their own feelings (Self-perspective), (2) consider the feelings of the person in the picture (Other-perspective), or (3) received no further instructions (Control). Eye movements provided indices of early (probability and duration

2020 Pain

10. Attentional biases in pediatric chronic pain: An eye-tracking study assessing the nature of the bias and its relation to attentional control. (Abstract)

Attentional biases in pediatric chronic pain: An eye-tracking study assessing the nature of the bias and its relation to attentional control. Attentional biases are posited to play a key role in the development and maintenance of chronic pain in adults and youth. However, research to date has yielded mixed findings and few studies have examined attentional biases in pediatric samples. The present study used eye-gaze tracking to examine attentional biases to pain-related stimuli in a clinical (...) sample of youth with chronic pain and pain-free controls. The moderating role of attentional control was also examined. Youth with chronic pain (n = 102) and pain-free controls (n = 53) viewed images of children depicting varying levels of pain expressiveness paired with neutral faces while their eye gaze was recorded. Attentional control was assessed using both a questionnaire and a behavioural task. Both groups were more likely to first fixate on high pain faces but showed no such orienting bias

2020 Pain

11. Eye Pain and Dry Eye in Patients with Fibromyalgia. (Abstract)

Eye Pain and Dry Eye in Patients with Fibromyalgia. The aim of this study was to examine visual function and eye symptoms in fibromyalgia patients, with a particular focus on dry eye syndrome and eye pain.A tertiary care center-based cross-sectional study was carried out in chronic musculoskeletal pain patients diagnosed with fibromyalgia. Chronic musculoskeletal pain patients without fibromyalgia were enrolled as a comparison group. Self-reported eye pain was investigated with the McGill pain (...) questionnaire and the numeric rating scale. In addition, we assessed corrected visual acuity, vision-related quality of life, and self-reported dry eye syndrome.A total of 90 musculoskeletal pain patients were included, with 66 patients fulfilling American College of Rheumatology 1990 criteria for fibromyalgia. Sixty-seven percent (95% confidence interval [CI] = 56%-78%) of the fibromyalgia patients reported eye pain, and 62% (95% CI = 43%-81%) of those were without fibromyalgia diagnosis. Sixty-seven

2018 Pain Medicine

12. The Relationship Between Ocular Itch, Ocular Pain, and Dry Eye Symptoms (An American Ophthalmological Society Thesis) Full Text available with Trip Pro

The Relationship Between Ocular Itch, Ocular Pain, and Dry Eye Symptoms (An American Ophthalmological Society Thesis) To evaluate associations between sensations of ocular itch and dry eye (DE) symptoms, including ocular pain, and DE signs.A cross-sectional study of 324 patients seen in the Miami Veterans Affairs eye clinic was performed. The evaluation consisted of questionnaires regarding ocular itch, DE symptoms, descriptors of neuropathic-like ocular pain (NOP), and evoked pain sensitivity (...) -ocular pain and demonstrate abnormal somatosensory testing in the form of increased sensitivity to evoked pain at a site remote from the eye, consistent with generalized hypersensitivity.

2018 Transactions of the American Ophthalmological Society

13. Eye trauma

to mechanical trauma (blunt or penetrating), chemical agents, or ultraviolet and ionising radiations. In the absence of severe ocular compromise, most conservative treatments for standard eye complaints produce healing within 48 to 72 hours. It is important to make the public aware of the benefits of using protective equipment because most eye injuries are preventable. Definition Refers to any injury to the eye. The injury may have been due to mechanical trauma (blunt or penetrating), chemical agents (...) , or radiation (ultraviolet or ionising). History and exam hyphaema ecchymosis severe eye pain blurred vision corneal abrasions corneal oedema corneal erosions sub-conjunctival haemorrhages conjunctival lacerations punctated epithelial erosions loss of sight excessive lacrimation conjunctival chemosis conjunctival hyperaemia corneal epithelial defect open globe injury eyelid burns photophobia diplopia miosis corneal stromal clouding iridodialysis conjunctival foreign body corneal foreign body Descemet's

2018 BMJ Best Practice

14. Evidence of central sensitisation in those with dry eye symptoms and neuropathic-like ocular pain complaints: incomplete response to topical anaesthesia and generalised heightened sensitivity to evoked pain. (Abstract)

Evidence of central sensitisation in those with dry eye symptoms and neuropathic-like ocular pain complaints: incomplete response to topical anaesthesia and generalised heightened sensitivity to evoked pain. To evaluate how closely neuropathic-like ocular pain (NOP) symptoms align with a metric of central sensitisation (ie, the presence of persistent ocular pain after topical anaesthetic placement) in individuals with dry eye (DE) symptoms.Cross-sectional study of 224 individuals with DE (...) symptoms seen in the Miami Veterans Affairs eye clinic. An evaluation was performed consisting of questionnaires regarding DE symptoms, NOP descriptors and evoked pain sensitivity testing on the forehead and forearm, followed by a comprehensive ocular surface examination including corneal mechanical sensitivity testing. Subsequent analyses were performed to examine for differences between those with and without ocular pain after topical anaesthetic placement.The mean age was 62 years with 91% being men

2017 British Journal of Ophthalmology

15. Investigating the effect of Eye Movement Desensitization and Reprocessing on pain intensity in patients with primary dysmenorrhea: a protocol for a randomized controlled trial. Full Text available with Trip Pro

Investigating the effect of Eye Movement Desensitization and Reprocessing on pain intensity in patients with primary dysmenorrhea: a protocol for a randomized controlled trial. Unpleasant experience with the previous menstruation can increase the sensitivity to pain which may lead to moderate to severe pain in patients with dysmenorrhea. Eye movement desensitization and reprocessing (EMDR) is a psychological method to alleviate the distress from unpleasant memories and related events and can (...) be used for other conditions such as anxiety, depression, and chronic pain. This protocol was designed to investigate the effect of EMDR therapy on pain intensity in patients with dysmenorrhea.A randomized clinical trial was designed in compliance with the Consolidated Standards of Reporting Trials (CONSORT). Female students who have moderate to severe primary dysmenorrhea (based on a visual analogue scale [VAS] score of at least 4 for two consecutive months) and who live in dormitories at Qazvin

2019 Trials Controlled trial quality: uncertain

16. Eye-movement behaviours when viewing real-world pain-related images. (Abstract)

Eye-movement behaviours when viewing real-world pain-related images. Pain-related cues are evolutionarily primed to capture attention, although evidence of attentional biases towards pain-related information is mixed in healthy individuals. The present study explores whether healthy individuals show significantly different eye-movement behaviours when viewing real-world pain-related scenes compared to neutral scenes. The effect of manipulating via written information the threat value (...) of the pain-related scenes on eye-movement behaviours was also assessed.Participants were randomized to threatening (n = 28) and non-threatening (n = 27) information conditions. All completed a free-viewing task with real-world pain-related and neutral images while their eye movements were recorded.Participants made significantly fewer fixations of significantly longer duration when viewing pain-related images compared to neutral images. No significant differences were found between threatening and non

2019 European Journal of Pain Controlled trial quality: uncertain

17. Innovations in topical ocular corticosteroid therapy for the management of postoperative ocular inflammation and pain. (Abstract)

Innovations in topical ocular corticosteroid therapy for the management of postoperative ocular inflammation and pain. Topical ophthalmic corticosteroids are of clinical benefit in the management of pain and inflammation after ocular surgery; however, their use can be associated with class-associated adverse events (AEs) and limited bioavailability. Selection of an appropriate topical corticosteroid depends on drug-specific variables such as AE profile, efficacy, potency, dosing, patient (...) ocular tissue penetration and resolution of pain and inflammation despite a reduced drug concentration (0.38%) and dosing frequency.

2019 American Journal Of Managed Care

18. Holoclar for treating limbal stem cell deficiency after eye burns

Farmaceutici) is a treatment used in the eye to replace damaged cells on the corneal surface. Mark Marketing eting authorisation authorisation It has a conditional marketing authorisation for 'the treatment of adult patients with moderate to severe limbal stem cell deficiency (defined by the presence of superficial corneal neovascularisation in at least 2 corneal quadrants, with central corneal involvement, and severely impaired visual acuity), unilateral or bilateral, due to physical or chemical ocular (...) . LSCD can either be unilateral (in 1 eye) or bilateral (in both eyes). The committee heard from the clinical experts that LSCD can be life-changing: in addition to visual impairment, the condition is associated with high levels of pain and photophobia. LSCD also represents a major psychological burden, both from the trauma of the original incident and the ongoing management of eye disfigurement. The highly visible nature of the injury can also impair a person's confidence and cause social isolation

2017 National Institute for Health and Clinical Excellence - Technology Appraisals

19. Eye injuries in people and dogs when using Osurnia ear gel for dogs

when applying the medicine. The dog should be properly restrained during administration of Osurnia and appropriate measures should be taken to avoid accidental eye contact with the product. If accidental ocular exposure occurs the eyes should be flushed thoroughly with water for 10 to 15 minutes. Veterinarians should also advise pet owners to monitor dogs treated with Osurnia and to contact their veterinarian in case of any side effects in particular those affecting the eyes. Side effects relating (...) Eye injuries in people and dogs when using Osurnia ear gel for dogs Eye injuries in people and dogs when using Osurnia ear gel for dogs | European Medicines Agency Search Search Menu Eye injuries in people and dogs when using Osurnia ear gel for dogs Press release 20/04/2018 Caution is advised when applying the medicine EMA's is warning of cases of eye injuries to pets or their owners from accidental eye exposure to the medicine Osurnia. Osurnia is an ear gel for the treatment of ear infections

2018 European Medicines Agency - EPARs

20. Efficacy of Care for Blind Painful Eyes. (Abstract)

Efficacy of Care for Blind Painful Eyes. Pain relief for a blind painful eye often follows an escalating paradigm of interventions. This study compares the efficacy of common interventions.A retrospective chart review of blind painful eye cases was conducted at a single tertiary institution from April 2012 to December 2016. Demographics, etiology, treatment, and pain level were assessed.Among 99 blind painful eyes, 96 eyes initially received medical therapy (topical steroids, cycloplegics (...) , and/or hypotensives), with pain relief in 39% of eyes. Minimally invasive interventions (laser cyclophotocoagulation, retrobulbar injection, or corneal electrocautery) were performed 41 times in 36 eyes, 34 of which had failed medical therapy, and led to pain relief in 75% of eyes. Evisceration or enucleation was performed in 28 eyes, and long-term pain relief was achieved in 100% of eyes. Surgery allowed discontinuation of oral analgesics in 100% of cases versus 20% for minimally invasive therapy (p = 0.005

2018 Ophthalmic plastic and reconstructive surgery Controlled trial quality: uncertain

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