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Eye Injury

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1. Interventions for eye movement disorders due to acquired brain injury. (PubMed)

Interventions for eye movement disorders due to acquired brain injury. Acquired brain injury can cause eye movement disorders which may include: strabismus, gaze deficits and nystagmus, causing visual symptoms of double, blurred or 'juddery' vision and reading difficulties. A wide range of interventions exist that have potential to alleviate or ameliorate these symptoms. There is a need to evaluate the effectiveness of these interventions and the timing of their implementation.We aimed (...) ) in eight people with downbeat nystagmus. Assessments were made 45 and 90 minutes after drug administration. This study provides very low-certainty evidence that both 3,4-DAP and 4-AP may reduce the mean slow-phase velocity in people with downbeat nystagmus. This effect may be stronger with 4-AP.The included studies provide insufficient evidence to inform decisions about treatments specifically for eye movement disorders that occur following acquired brain injury. No information was obtained on the cost

2018 Cochrane

2. Eye Injuries across history and the evolution of eye protection. (PubMed)

Eye Injuries across history and the evolution of eye protection. To describe the history of eye injuries and the consequent evolution of eye protection.A comprehensive search of Medline and the grey literature using the terms 'ocular trauma' and 'eye protection' or 'injury prevention' and 'history'. References were used to identify other relevant publications. Publications were classified according to the setting of eye injury: occupational, recreational or combat-related.Eye protection has (...) been described in a wide range of sources, including in literature and art. With advances in eye protection material and design, as well as government and societal promotion of appropriate eye protection usage in the workplace, the epidemiology of ocular trauma has changed over time. In developed countries, the use of eye protection in the workplace has reduced the proportion of occupation-related eye injuries over the last century, with a higher proportion occurring during sports or at home. New

2019 Acta ophthalmologica

3. Toy gun eye injuries - eye protection needed Helsinki ocular trauma study. (PubMed)

Toy gun eye injuries - eye protection needed Helsinki ocular trauma study. We report the epidemiology, findings, treatment, long-term outcome and use of resources for eye injuries caused by toy guns in southern Finland.All new patients injured by toy guns in one year (2011-2012) and treated at Helsinki University Eye Hospital were included. Follow-ups occurred at 3 months and 5 years.Toy guns caused 15 eye traumas (1% of all eye traumas). Most patients were male (n = 14) and children aged under (...) intraocular lens, two iridodialysis, and one each retinal plomb, mydriasis or iris tear. None had glaucoma. Seven patients had permanent subjective impairment due to pain, lowered visual acuity, blur or difficulty in focusing. Four patients needed seven operations. The number of outpatient visits was 90. One patient required hospitalization.Toy guns cause serious eye traumas. No glaucoma was found. Proper use of toy guns and protective eyewear during the whole game should be emphasized to both players

2018 Acta ophthalmologica

4. Eye injuries in people and dogs when using Osurnia ear gel for dogs

Eye injuries in people and dogs when using Osurnia ear gel for dogs Eye injuries in people and dogs when using Osurnia ear gel for dogs | European Medicines Agency Search Search Menu Eye injuries in people and dogs when using Osurnia ear gel for dogs Press release 20/04/2018 Caution is advised when applying the medicine EMA's is warning of cases of eye injuries to pets or their owners from accidental eye exposure to the medicine Osurnia. Osurnia is an ear gel for the treatment of ear infections (...) in dogs. Eye exposure in people mostly happened when the dog shook its head during or just after applying the medicine. It is not clear if cases in dogs were also due to accidental contact, although this was confirmed in a few reports. The injuries in people include 2 cases of corneal ulcer (damage to the clear layer at the front of the eye), as well as reports of eye irritation, conjunctivitis, redness, burning, stinging and itchiness. The eye injuries in dogs included corneal ulcers, squinting

2018 European Medicines Agency - EPARs

5. Nonvitreoretinal Eye Injuries in 2 Infants Due to Nonaccidental Trauma. (PubMed)

Nonvitreoretinal Eye Injuries in 2 Infants Due to Nonaccidental Trauma. Intraocular findings are well known and well documented in child abuse cases. However, eye deviation on physical examination can also be just as important in evaluating a child for maltreatment. We present 2 cases of infants younger than 6 months who presented to the emergency department with new-onset abnormal eye deviation, and further evaluation revealed other findings consistent with nonaccidental trauma. These cases

2019 Pediatric Emergency Care

6. Diagnosis of Traumatic Eye Injuries With Point-of-Care Ocular Ultrasonography in the Emergency Department. (PubMed)

Diagnosis of Traumatic Eye Injuries With Point-of-Care Ocular Ultrasonography in the Emergency Department. Traumatic eye injuries are common emergency department presentations worldwide, and diagnosis may be delayed because of concurrent injuries and lack of guidelines in regard to the utility of clinical examination, computed tomography (CT), and point-of-care ultrasonography. In this study, we compare point-of-care ultrasonography with ophthalmologist clinical examination and CT for 6 types (...) of traumatic eye injury.We conducted a prospective cohort study evaluating patients with suspected traumatic eye injury who were recruited at an academic medical center in Tabriz, Iran. Each patient was evaluated by an emergency physician with point-of-care ultrasonography using a 7- to 15-MHz linear transducer, by a radiologist with orbital CT imaging, and by an ophthalmologist with a complete bedside ocular examination. Obtained results were tabulated. Sensitivity, specificity, and likelihood ratios were

2019 Annals of Emergency Medicine

7. Waterless wipes for chemical eye injuries: clinical effectiveness

Waterless wipes for chemical eye injuries: clinical effectiveness Waterless wipes for chemical eye injuries: clinical effectiveness Waterless wipes for chemical eye injuries: clinical effectiveness CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Waterless wipes for chemical eye injuries: clinical effectiveness. Ottawa (...) : Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response. 2014 Authors' conclusions No relevant literature was found regarding the clinical effectiveness of waterless wipes for the treatment of chemical eye injuries in adults. Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Burns, Chemical; Eye Burnss; Eye Injuries Language Published English Country of organisation Canada Province or state Ontario English summary An English language summary is available

2014 Health Technology Assessment (HTA) Database.

8. Eye injury from electrical weapon probes: Mechanisms and treatment. (PubMed)

Eye injury from electrical weapon probes: Mechanisms and treatment. While generally reducing morbidity and mortality, TASER® electrical weapons have risks associated with their usage, including burn injuries and head and cervical trauma associated with uncontrolled falls. The primary non-fatal complications appear to be significant eye injury but no analysis of the mechanisms or suggested treatments has been published.We used a biomechanical model to predict the risk of eye injury as a function (...) is expected along with a perforation by the dart portion of the probe. Our prediction of globe rupture out to 6 m (out of a typical range of 9 m) is consistent with the published risk of enucleation or unilateral blindness being 69 ± 18%, with an eye penetration.Significant eye injury is expected from a penetration by an electrical weapon probe at close range. The risk decreases rapidly at extended distances from the muzzle. Not all penetrating globe injuries from electrical weapon probes will result

2018 American Journal of Emergency Medicine

9. Pediatric Sports- and Recreation-Related Eye Injuries Treated in US Emergency Departments. (PubMed)

Pediatric Sports- and Recreation-Related Eye Injuries Treated in US Emergency Departments. To investigate the epidemiologic characteristics of sports- and recreation-related eye injuries among children in the United States.Data from the National Electronic Injury Surveillance System were analyzed in a retrospective study of children ≤17 years of age treated in US emergency departments for sports- and recreation-related eye injuries from 1990 to 2012.From 1990 through 2012, an estimated 441 800 (...) (95% confidence interval: 378 868-504 733) children were treated in US emergency departments for sports- and recreation-related eye injuries, averaging 26.9 injuries per 100 000 children. Children 10 to 14 and 15 to 17 years old had the highest rate of eye injury. Three-fourths of injuries were sustained by boys. The most common types of injury were corneal abrasion (27.1%), conjunctivitis (10.0%), and foreign body in the eye (8.5%). Most eye injuries were treated and released (94.6%); however

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2018 Pediatrics

10. Comparison of the effects of intravitreal bevacizumab and dexamethasone in experimental posterior penetrating eye injury (PubMed)

Comparison of the effects of intravitreal bevacizumab and dexamethasone in experimental posterior penetrating eye injury To compare the effects of intravitreal anti-vascular endothelial growth factor (VEGF) and dexamethasone in an experimental rabbit model of posterior penetrating ocular injury.Thirty white New Zealand rabbits were included in the study. A posterior penetrating ocular injury was performed at the superotemporal quadrant. They were randomly divided into three groups. The rabbits (...) in group 1 received intravitreal dexamethasone, in group 2 they received intravitreal bevacizumab and those in group 3 received intravitreal physiological saline solution in both eyes. All eyes were examined ophthalmologically on the 1st, 3rd, 7th, 14th and 28th days following the injury and the clinical findings were scored. On the day 28, the eyes were enucleated, evaluated and scored macroscopically, histopathologically and scanning electron microscopically.The median clinical score on the 14th

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2018 International journal of ophthalmology

11. Impact on the pattern of ocular injuries and awareness following a ban on firecrackers in New Delhi: A tertiary eye hospital-based study (PubMed)

Impact on the pattern of ocular injuries and awareness following a ban on firecrackers in New Delhi: A tertiary eye hospital-based study To review the nature of firecracker-related ocular injuries at a tertiary eye hospital in northern India following the firecracker ban and also to review the level of awareness among the victims.A cross-sectional observational study involving the patients presenting with firecracker-related ocular injuries from October 18 to 27, 2017 were assessed (...) for demographic distribution, detailed ocular evaluation, and a questionnaire related to the awareness about the injuries.A total of 68 patients were observed. Fifty patients (74.5%) were males. This year, a majority of patients were from outside Delhi. Uttar Pradesh constituted the most 38.23% of the patients followed by Haryana 30.88%, Delhi 23.5%, and Bihar 7.35%. Visual acuity varied from 6/6 to no perception of light. Open globe injury was observed in 56 patients (82.35%) who commonly had zone I injury

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2018 Indian journal of ophthalmology

12. Acute hyperalgesia and delayed dry eye after corneal abrasion injury (PubMed)

Acute hyperalgesia and delayed dry eye after corneal abrasion injury Corneal nerves mediate pain from the ocular surface, lacrimation, and blinking, all of which protect corneal surface homeostasis and help preserve vision. Because pain, lacrimation and blinking are rarely assessed at the same time, it is not known whether these responses and their underlying mechanisms have similar temporal dynamics after acute corneal injury.We examined changes in corneal nerve density, evoked and spontaneous (...) pain, and ocular homeostasis in Sprague-Dawley male rats after a superficial epithelial injury with heptanol. We also measured changes in calcitonin gene-related peptide (CGRP), which has been implicated in both pain and epithelial repair.Hyperalgesia was seen 24 hours after abrasion injury, while basal tear production was normal. One week after abrasion injury, pain responses had returned to baseline levels and dry eye symptoms emerged. There was no correlation between epithelial nerve density

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2018 Pain Reports

13. Aucuba japonica Extract and Aucubin Prevent Desiccating Stress-Induced Corneal Epithelial Cell Injury and Improve Tear Secretion in a Mouse Model of Dry Eye Disease (PubMed)

Aucuba japonica Extract and Aucubin Prevent Desiccating Stress-Induced Corneal Epithelial Cell Injury and Improve Tear Secretion in a Mouse Model of Dry Eye Disease Dry eye disease is affected by a broad range of causes such as age, lifestyle, environment, medication and autoimmune diseases. These causes induce tear instability that activates immune cells and promotes expression of inflammatory molecules. In this study, we investigated the therapeutic effects of an ethanolic extract of Aucuba (...) japonica (AJE) and its bioactive compound, aucubin, on dry eye disease. The human corneal cells were exposed to desiccation stress induced by exposing cells to air, so that viability was decreased. On the other hand, pre-treatment of AJE and aucubin restored cell survival rate depending on the dose under the dry condition. This result was confirmed again by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining. The mRNA expression of inflammatory molecules was reduced

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2018 Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

14. Emergency management: penetrating eye injuries and intraocular foreign bodies (PubMed)

Emergency management: penetrating eye injuries and intraocular foreign bodies 30487690 2018 12 07 0953-6833 31 103 2018 Community eye health Community Eye Health Emergency management: penetrating eye injuries and intraocular foreign bodies. 70-71 Mwangi Nyawira N Research Fellow: London School of Hygiene and Tropical Medicine, London, UK. Mutie Dorothy M DM Ophthalmologist/Lecturer: Kenya Medical Training College, Nairobi, Kenya. eng Journal Article England Community Eye Health 8912615 0953 (...) -6833 2018 11 30 6 0 2018 11 30 6 0 2018 11 30 6 1 ppublish 30487690 PMC6253309 Can J Ophthalmol. 2013 Feb;48(1):8-12 23419293 Community Eye Health. 2015;28(91):46-8 26989310 Surv Ophthalmol. 2016 Sep-Oct;61(5):582-96 26994871

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2018 Community Eye Health

15. A case of drug induced lung injury caused by levofloxacin eye drops (PubMed)

A case of drug induced lung injury caused by levofloxacin eye drops A 78 year-old man, who received levofloxacin eye drops as a perioperative prophylactic antibacterial agent for cataract surgery, developed pyrexia and dyspnea, followed by respiratory failure. He was diagnosed as drug-induced lung injury due to levofloxacin, and the symptoms improved after the administration of corticosteroids and discontinuation of levofloxacin eye drops. The incidence of levofloxacin-induced lung injury (...) is rare for its frequent prescription. Moreover, eye drops of it has never been reported to cause lung injury. We should be aware of eye drops as a causative dosage forms of drug-induced lung injury.

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2018 Respiratory Medicine Case Reports

16. Paediatric eye injuries in Finland - Helsinki eye trauma study. (PubMed)

Paediatric eye injuries in Finland - Helsinki eye trauma study. To determine the current population-based epidemiology, treatment, use of resources and outcomes of children's eye injuries in Finland.The study included all new patients, 16 years of age or under, with ocular or orbital traumas taken into care to the Helsinki University Eye Hospital (population base 1.5 million people) in 1 year. The follow-up period was 3 months.Two hundred and two children's eye injuries were treated. The eye (...) injury incidence was 5.2-8.3 per 10 000 per year, including all minor and major eye traumas. Eye injury most likely occurred at the junior high school age (13-16 years). Thirty-three percentage of accidents took place at home and 24% at school or in day care. The most common causes were sports equipment (15%), contact with human body (12%) and superficial foreign bodies (11%). Excluding minor injuries, contusion was the most common diagnosis (n = 60, 30%). Eighty-seven percentage of contusion

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2016 Acta ophthalmologica

17. Ocular injuries and eye care seeking patterns following injuries among cocoa farmers in Ghana (PubMed)

Ocular injuries and eye care seeking patterns following injuries among cocoa farmers in Ghana The work environment of cocoa farmers exposes them to several ocular hazards that predispose them to eye diseases and injuries. However, the extent of ocular injuries and health seeking patterns following these injuries are unknown among cocoa farmers in Ghana.To determine the prevalence of ocular injuries and health seeking behaviour following injury among cocoa farmers in Ghana.Five hundred and fifty (...) six participants were recruited through simple random sampling using a multistage approach from four cocoa growing districts in Ghana. A structured questionnaire was used to collect relevant information such as demography, ocular hazards and injuries experienced. An ocular examination was also conducted to assess the eye health of the participants. Descriptive and regression statistics were used to analyze the data. The rate of ocular injuries was calculated by using the number of injuries

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2016 African health sciences

18. Eye trauma

Eye trauma Eye trauma - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Eye trauma Last reviewed: February 2019 Last updated: March 2018 Summary A leading cause of visual loss and blindness that frequently affects young people. Worldwide, there are approximately 1.6 million people blind from eye injuries, 2.3 million with bilateral visual impairment, and 19 million with unilateral visual loss. The injuries may be due (...) to mechanical trauma (blunt or penetrating), chemical agents, or ultraviolet and ionising radiations. In the absence of severe ocular compromise, most conservative treatments for standard eye complaints produce healing within 48 to 72 hours. It is important to make the public aware of the benefits of using protective equipment because most eye injuries are preventable. Definition Refers to any injury to the eye. The injury may have been due to mechanical trauma (blunt or penetrating), chemical agents

2018 BMJ Best Practice

19. The mechanics of corneal deformation and rupture for penetrating injury in the human eye. (PubMed)

The mechanics of corneal deformation and rupture for penetrating injury in the human eye. Penetrating eye injuries are surgical emergencies with guarded visual prognosis. The purpose of the current study was to determine the force required to rupture the cornea with a penetrating object, and to study how this force is affected by the object geometry. Thirty-six human cadaveric eyes from donors of various ages were characterized for diameter, axial length, and pre-test intraocular pressure (...) (p<0.001), and globe diameter (p<0.041), but was not associated with pre-test intraocular pressure, tissue postmortem time, axial length, or speed of the indenter. This study has quantified the force-displacement and failure response of a large series of human cadaveric eyes subjected to penetrating indentation loads on the cornea. The results provide useful data for characterizing the relationship between corneal rupture and the geometry of a penetrating object.Copyright © 2017 Elsevier Ltd. All

2017 Injury

20. Traumatic brain injury, dry eye and comorbid pain diagnoses in US veterans. (PubMed)

Traumatic brain injury, dry eye and comorbid pain diagnoses in US veterans. The purpose of the study is to evaluate the relationship between dry eye (DE) and pain diagnoses in US veterans with and without traumatic brain injury (TBI).Retrospective cohort study of veterans who were seen in the Veterans Administration Hospital (VA) between 1 January 2010 and 31 December 2014. Veterans were separated into two groups by the presence or absence of an International Classification of Diseases, Ninth (...) with tear film dysfunction (OR 1.09; 95% CI 1.07 to 1.10). Those with TBI were also about twice as likely to have a diagnosis of chronic pain, headache, depression or post-traumatic stress disorder compared with their counterparts without TBI. Cluster analysis of TBI, DE and pain diagnoses of interest revealed that central pain syndrome, cluster headache, sicca syndrome, keratoconjunctivitis sicca and late effect of injury to the nervous system (as can be seen after TBI) were all closely clustered

2017 British Journal of Ophthalmology

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