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Esophageal Rupture

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761. Efficacy and Safety Study of Bevacizumab and Erlotinib to Treat Primary Liver Cancer That Cannot be Removed By Surgery

-melanoma skin cancer or cervical dysplasia, within five years prior to protocol entry. History of ruptured Hepatocellular carcinoma (HCC) lesion, or HCC lesion with large necrotic areas seen on conventional imaging studies, as determined by the Principal Investigator. Abnormalities of the cornea based on history (eg dry eye syndrome, Sjogren's syndrome) or congenital abnormality (eg Fuch's dystrophy). Gastrointestinal disease resulting in an inability to take oral medication or a requirement (...) ) that is refractory to medical management. Patients may not have received any other investigational agents nor have received any systemic chemotherapy esophageal or gastric varices; evidence of hepatic cirrhosis and/or portal

2005 Clinical Trials

762. A Research Study to Test (2) Two Different Types of Feeding Tubes Used in the Intensive Care Unit

contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: all ICU patients requiring enteral nutrition Exclusion Criteria: coagulopathy, esophageal or gastric, surgery, varices, trauma, ulcer, structure, rupture Contacts and Locations Go to Information from the National

2005 Clinical Trials

763. Comparison of Oral Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting

admission in patients with high risk for PONV treated with oral aprepitant with or without transdermal scopolamine preoperatively. Condition or disease Intervention/treatment Phase Nausea Vomiting Drug: Aprepitant Drug: Scopolamine Not Applicable Detailed Description: Postoperative nausea and vomiting (PONV) is a serious problem complicating surgery. PONV has an overall incidence of 30% and a 70% incidence in high-risk patients. PONV yields unplanned hospital admission, pulmonary aspiration, esophageal (...) rupture, electrolyte abnormalities, dehydration, and delayed discharge from the postanesthesia care unit (PACU). Additional use of resources costs the health care industry hundreds of millions of dollars annually. Patient satisfaction is greatly improved when PONV is prevented.4 PONV etiology is multifactorial and the treatment is multimodal. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 115 participants Allocation: Randomized

2008 Clinical Trials

764. Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm

-feeding female. A pregnancy test will be performed in all female patients less than 60 years of age. Any contraindication to insertion/exchange a nasogastric tube, including (but not limited to): severe oropharyngeal malformation or bleeding; esophageal varices, tumor, infection, stenosis, or rupture Presence or suspicion of diaphragm injury Hemophilia or other severe bleeding disorder Presence or suspicion of a central nervous system (CNS) disorder, including (but not limited to): CNS infarction

2007 Clinical Trials

765. Comparison of Endoscopic Injection of Conventional and Double Doses Cyanoacrylate for Gastric Variceal Hemorrhage

and achieve better hemostasis. Condition or disease Intervention/treatment Phase Gastric Variceal Bleeding Procedure: Cyanoacrylate Phase 4 Detailed Description: Although outcome of variceal hemorrhage has been improved in the last two decades, variceal hemorrhage is still the most serious complication of portal hypertension and chronic liver disease. Occurrence of gastric varices (GV) rupture is less often than esophageal varices (EV) but it is characteristic of higher rebleeding rate and mortality

2008 Clinical Trials

766. Combination Antiemetic Regimen for Prevention of PONV in Breast Surgery Patients

in the surgical patient can cause wound dehiscence, electrolyte imbalance, increased intraocular pressure, increased intracranial pressure, aspiration, esophageal rupture, and loss of vision due to retinal detachment. 6-11 In several studies, investigators found that patients rank vomiting as the most undesirable common side effect after surgery. PONV is costly in economic terms and is a reason day surgery patients must be admitted in the hospital for an overnight stay.12, 13 It is estimated that a patient

2008 Clinical Trials

767. Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm

a nasogastric tube, including (but not limited to): severe oropharyngeal malformation or bleeding; esophageal varices, tumor, infection, stenosis, or rupture Presence or suspicion of diaphragm injury Hemophilia or other severe bleeding disorder Presence or suspicion of a central nervous system (CNS) disorder, including (but not limited to): CNS infarction, bleeding, tumor, or infection History of heart and/or lung transplantation Any mechanical cardiac assist device (including intraaortic balloon pump) Any

2008 Clinical Trials

768. Endoscopic Cyanoacrylate Obliteration vs. Nadolol Treatment in the Prevention of Gastric Variceal Rebleeding

choice of endoscopic treatment. Beta-blocker (BB) is effective to lower portal pressure. We hypothesized combination of GVO and BB can further decrease the rebleeding rate. Condition or disease Intervention/treatment Phase Liver Cirrhosis and Hepatoma. Gastric Variceal Bleeding Drug: Nadolol Phase 4 Detailed Description: Gastric varies (GV) rarely rupture. However should it occur, the outcome would be worse than rupture of esophageal varies (EV). Rupture of GV is characteristic of a higher rebleeding (...) a fast blood flow. Therefore, voluminous blood in the larger diameter GV leads to exsanguine bleeding when ruptured. A variety of endoscopic methods, which include injection of sclerosants, tissue adhesive (cyanoacrylate), thrombin and ligation with rubber bands, detachable nylon loop and steel snares, are applied to control acute GV bleeding with variable successful rates (50~100%) and rebleeding rates (20~90%). The successful rate of endoscopic cyanoacrylate injection to arrest active GVB is more

2007 Clinical Trials

769. Neurally Adjusted Ventilatory Assist (NAVA) in Patients With Critical Illness Associated Polyneuropathy / or Polymyopathy (CIP/M)

The patient refuses informed consent Next of kin is unavailable or refuses informed consent The independent physician refuses informed consent Pregnant or breast-feeding female. A pregnancy test will be performed in all female patients less than 60 years of age Any contraindication to insertion/exchange a nasogastric tube, including (but not limited to): severe oropharyngeal malformation or bleeding; esophageal varices, tumor, infection, stenosis, or rupture, bleeding disorder with evidence of active

2008 Clinical Trials

770. Effect of Meal on Portal and Esophagus Variceal Pressure

Information provided by: Hvidovre University Hospital Study Details Study Description Go to Brief Summary: The reason why esophagus varices suddenly rupture and start to bleed is unclear. Food intake increase the hepatic blood flow and the portal pressure, but it is yet unknown if there is also an increase in variceal pressure. The aim of this study is to evaluate the efficacy of a meal on variceal pressure with a non invasive endoscopic measurement device, and compare it with portal pressure. Condition (...) or disease Intervention/treatment Phase Cirrhosis Esophageal Varices Behavioral: meal (food intake) Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 0 participants Intervention Model: Single Group Assignment Masking: None (Open Label) Primary Purpose: Basic Science Official Title: Effect of Meal on Portal and Esophagus Variceal Pressure Study Start Date : June 2007 Actual Primary Completion Date : April 2008 Actual Study

2007 Clinical Trials

771. 24-Hour NAVA Ventilation in Acute Respiratory Failure

these criteria will be considered eligible for recruitment into the study General Exclusion Criteria: Next of kin unavailable Patient/next of kin refuses informed consent. Attending physician refuses to allow enrollment Pregnancy Exclusion Criteria Related to the Technique: Any contraindication to insertion of a nasogastric tube including, but not limited to: severe oropharyngeal malformation or bleeding, esophageal varices, tumor, infection, stenosis, or rupture Hemophilia or other severe bleeding disorder

2007 Clinical Trials

772. An unusual cause of postoperative dyspnoea Full Text available with Trip Pro

An unusual cause of postoperative dyspnoea 15306585 2004 10 04 2016 11 24 0017-5749 53 9 2004 Sep Gut Gut An unusual cause of postoperative dyspnoea. 1278, 1286 Cadet B B Department of Trauma and Orthopaedics, York Hospital, York, UK. Ashford R U RU Joseph S S De Boer P P Miller G V GV eng Case Reports Journal Article England Gut 2985108R 0017-5749 AIM IM Aged Diagnosis, Differential Dyspnea etiology Esophageal Diseases complications diagnostic imaging Humans Male Postoperative Complications (...) Pulmonary Embolism diagnosis Rupture, Spontaneous Tomography, X-Ray Computed 2004 8 13 5 0 2004 10 5 9 0 2004 8 13 5 0 ppublish 15306585 10.1136/gut.2003.033241 53/9/1278 PMC1774172

2004 Gut

773. An acute left‐sided hydrothorax Full Text available with Trip Pro

An acute left‐sided hydrothorax 17440182 2007 05 29 2016 11 24 0017-5749 56 5 2007 May Gut Gut An acute left-sided hydrothorax. 644, 698 Chou Hsien-Ling HL Department of Emergency Medicine, Chang Gung Memorial Hospital, Linko Medical Center, Taoyuan, Taiwan. Chang Shy-Shin SS Lee Chieng-Chang CC eng Case Reports Journal Article England Gut 2985108R 0017-5749 AIM IM Acute Disease Aged Esophageal Diseases complications Esophagus Foreign Bodies complications Humans Hydrothorax diagnostic imaging (...) etiology Male Pleural Effusion diagnostic imaging etiology Rupture, Spontaneous complications Tomography, X-Ray Computed 2007 4 19 9 0 2007 5 30 9 0 2007 4 19 9 0 ppublish 17440182 56/5/644 10.1136/gut.2006.096123 PMC1942166

2007 Gut

774. Perforation of the esophagus caused by the insertion of an intragastric balloon for the treatment of obesity. (Abstract)

surgery. Although intragastric balloons are advocated as safe devices, major complications such as intestinal obstruction, gastric perforation and gastric ulceration have been described. We report a case of esophageal rupture due to insertion of an intragastric balloon for the treatment of morbid obesity, for which no contraindication existed. When abnormal pain or discomfort arises, or esophageal damage is noted after insertion of an intragastric balloon, patients must be closely monitored (...) to diagnose a possible esophageal rupture early and thereby prevent severe complications.

2006 Obesity Surgery

775. BioEnterics Intragastric Balloon: The Italian Experience with 2,515 Patients. (Abstract)

positioning and were successfully treated by balloon removal. Balloon rupture (n=9; 0.36%) was not prevalent within any particular period of BIB treatment, and was also treated by BIB removal. Esophagitis (n=32; 1.27%) and gastric ulcer (n=5; 0.2%) presented in patients without a history of peptic disease and were treated conservatively by drugs. Preoperative co-morbidities were diagnosed in 1,394/2,471 patients (56.4%); these resolved in 617/1,394 (44.3%), improved (less pharmacological dosage or shift

2005 Obesity Surgery

776. An unusual type of severe barotrauma owing to automobile tire biting in a child. (Abstract)

An unusual type of severe barotrauma owing to automobile tire biting in a child. The authors report a rare case of a barotraumatic pneumothorax and pneumomediastinum associated with esophageal perforation and orbital emphysema. A 4-year-old boy presented with sudden respiratory distress after blowout of a defective tire that he bit. Computed tomography scan showed right pneumothorax and bilateral orbital emphysema. A linear rupture has been detected in the cervical esophagus in esophagoscopy

2004 Journal of Pediatric Surgery

777. Pediatric gastroesophageal varices: treatment strategy and long-term results. (Abstract)

were used in combination.Eighty-two prophylactic EVCs were done, and variceal progression was prevented in 89.9%. However, some patients had persistent red color signs and required frequent EVC. Ten emergent procedures were done for variceal rupture, and, in 4 cases, EVL was used to arrest massive variceal bleeding. Five patients developed bleeding during follow-up cause by rupture of gastric fundal varices, which probably had been aggravated by prior treatment for esophageal varices.The control (...) Pediatric gastroesophageal varices: treatment strategy and long-term results. There are various treatment strategies for gastroesophageal varices in children. We studied the therapeutic value of endoscopic variceal clipping (EVC) and ligation (EVL).Four hundred ninety-nine endoscopic examinations performed between 1991 and 2005 were retrospectively analyzed. F2 and F3 varices with red color signs on follow-up endoscopy were treated with prophylactic EVC. In variceal rupture cases, EVC and EVL

2006 Journal of Pediatric Surgery

778. Application of endograft to treat thoracic aortic pathologies: a single center experience. Full Text available with Trip Pro

(2.8%) aorto-bronchial fistulas (AoBF), 4 (1.2%) embolization, and 1 (0.3%) aorto-esophageal fistula (AoEF). Preoperative aneurysm sac size in TAA ranged from 5 to 12 centimeters, average size 6.3 cm. Sac shrinkage occurred in 65% (102 of 157) of patients. Average postoperative sac size of 5.4 cm in a mean follow-up of 20.4 months. One hundred cases (31.5%) were nonelective; 49 (15.1%) were ruptures. Overall complication was 22.7%, 14.2% (46) in elective cases and 8.5% (28) in nonelective cases

2007 Journal of Vascular Surgery

779. The best 10 clinical articles for the last 50 years from the Division of General Surgery, Hospital for Sick Children, Toronto, Ontario, Canada. (Abstract)

, necrotizing enterocolitis, esophageal replacement, Hirschsprung's disease, tracheal compression, fecal incontinence, gastroesophageal reflux, diaphragmatic hernia, and ruptured appendix. There were 8 staff members and 5 surgical residents/fellows who were lead authors, along with 10 staff from other divisions, departments, and/or hospitals.The conservative management of splenic trauma was judged the best article from this Division that made the largest clinical impact for the last 50 years.

2008 Journal of Pediatric Surgery

780. Gastroesophageal reflux disease as a cause of death is increasing: analysis of fatal cases after medical and surgical treatment. (Abstract)

%), aspiration pneumonia (41, 23%), ulcer perforation (25, 14%), rupture with esophagitis (15, 9%), and stricture (13, 7%).Regardless of the increased use of health resources, mortality from GERD, especially with medical treatment, rose. Surgery for GERD was also associated with early mortality and usually could not prevent the fatal outcome. (...) surgery, including fundoplication and gastric and esophageal resection, remained around 1.9/1,000 operations. Of the 213 patients whose cause of death was considered to be GERD, 180 (85%) had received medical treatment, including 4 patients whose death was related to either diagnostic or therapeutic endoscopy. Early complications of antireflux surgery caused 24 (11%) deaths; 9 (4%) were late failures of antireflux surgery. Causes of death in the medical group were hemorrhagic esophagitis (82, 47

2007 American Journal of Gastroenterology

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