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849 results for

Esophageal Rupture

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741. Dyspnea in Advanced Cancer Patients

Station) Acute respiratory distress requiring intubation Delirium as indicated by a Memorial Delirium Assessment Scale (MDAS) of 13 or higher Glasglow coma scale <8 Excessive airway secretions interfering with BIPAP administration History of facial trauma within 1 month of enrollment Upper GI bleed within 2 weeks of enrollment or esophageal rupture Partial or complete small bowel obstruction or severe nausea/vomiting (ESAS nausea >7/10) within 48 hours of enrollment Hemoglobin <8 g/dL at the time

2009 Clinical Trials

742. Study of Epicutaneously Applied Ketoprofen Transfersome® Gel With or Without Combination With Oral Celecoxib for the Treatment of Muscle Pain Induced by Eccentric Exercise

vascular disorders of the lower extremities Major traumatic lesions (e.g. fracture, tendon or muscle ruptures) of the musculo-skeletal system of the lower limbs Pain conditions which might interfere with pain rating during the study, e.g. neuropathic pain Significant neurological or psychiatric symptoms resulting in disorientation, memory impairment, or inability to report accurately (e.g. Alzheimer's disease or schizophrenia or other psychosis), that in the investigator's opinion may affect efficacy (...) History of pancreatitis or peptic ulcers Inflammatory GI disease (e.g. M. Crohn, colitis ulcerosa) Reflux esophagitis requiring treatment Any other analgesic therapy including cough and cold drugs containing analgesic properties as well as any other substance used for the treatment of pain during the study observation period (Screening to final Visit) Any other drug that might alter pain perception like CNS active drugs Contacts and Locations Go to Information from the National Library of Medicine

2009 Clinical Trials

743. Primary Aortoesophageal Fistula due to Thoracic Aortic Aneurysm: Successful Surgical Treatment Full Text available with Trip Pro

Primary Aortoesophageal Fistula due to Thoracic Aortic Aneurysm: Successful Surgical Treatment Aortoesophageal fistula is a rare emergency that presents a real challenge for cardiothoracic surgeons. There have been few reports of survivors. We present the case of a 70-year-old man with aortoesophageal fistula, mediastinal abscess, and severe septicemia consequent to esophageal erosion and rupture of a chronic degenerative descending thoracic aortic aneurysm. The patient underwent successful (...) surgical treatment by aorto-aortic bypass and bipolar esophageal exclusion in conjunction with a cervical esophagostomy and a feeding gastrostomy. The pleural cavity was copiously irrigated and drained. Three months later, a retrosternal gastric bypass operation was performed successfully. The patient's 6-month follow-up examination revealed no problems.

2009 Texas Heart Institute Journal

744. Unique case of esophageal rupture after a fall from height. Full Text available with Trip Pro

Unique case of esophageal rupture after a fall from height. Traumatic ruptures of the esophagus are relatively rare. This condition is associated with high morbidity and mortality. Most traumatic ruptures occur after motor vehicle accidents.We describe a unique case of a 23 year old woman that presented at our trauma resuscitation room after a fall from 8 meters. During physical examination there were no clinical signs of life-threatening injuries. She did however have a massive amount (...) presents a high cervical esophageal rupture without associated local injuries after a fall from height.

2009 BMC Emergency Medicine

746. Natural Orifice Translumenal Endoscopic Surgery for intra-abdominal surgery: a systematic review

for severe cases of chronic pancreatitis (Bengmark 2006; Kaido 2006; Larson et al. 2006). ? Splenectomy is commonly performed to treat many haematologic conditions including splenic trauma or spontaneous rupture, idiopathic thrombocytopenia purpura(Koene 2006), haemolytic anaemia, portal hypertension and hypersplenism, lymphoma and leukaemia (Forsythe et al. 2006; Katz and Pachter 2006; Koene 2006; Rhodes et al.). ? Appendicectomy is one of the most common emergency abdominal surgical procedures (Humes


747. Centralisation of selected surgical procedures: implications for Australia: a systematic review

OF CENTRALISATION JULY 2007 - List of Tables Table 1: Databases searched 10 Table 2: NHMRC Hierarchy of evidence (NHMRC 2000) 11 Table 3: Total number of included studies per procedure of interest 14 Table 4: Summary of included unruptured abdominal aortic aneurysm studies 17 Table 5: Summary of included ruptured abdominal aortic aneurysm studies 18 Table 6: Summary of included pooled abdominal aortic aneurysm studies 19 Table 7: Summary of hospital volume definitions 21 Table 8: Summary of surgeon volume (...) , unruptured abdominal aortic aneurysm 32 Table 17: Hospital volume length of stay outcomes, unruptured abdominal aortic aneurysm 33 Table 18: Hospital volume mortality outcomes, ruptured abdominal aortic aneurysm 33 Table 19: Hospital volume length of stay outcomes, ruptured abdominal aortic aneurysm 34 Table 20: Hospital volume mortality outcomes, unclear abdominal aortic aneurysm type 35 Table 21: Hospital volume length of stay outcomes, unclear abdominal aortic aneurysm type 36 Table 22: Surgeon volume


748. Cost-effectiveness analysis of the terlipressin-glycerin trinitrate combination in the pre-hospital management of acute gastro-intestinal haemorrhage in cirrhotic patients

) combination, administered before endoscopy, was used for the early treatment of upper gastrointestinal haemorrhages due to rupture of oesophageal varices (ROV), in cirrhotic patients suffering from portal hypertension. TER was administered through intravenous injections at home, then associated with GTN via the application of a patch (10 mg GTN over 24 hours). This was followed by the endoscopic diagnosis of ROV and admission to the intensive care unit (ICU). Intravenous administration of TER comprised 1 (...) : Intensive Care Medicine 1999;25:345-7. Indexing Status Subject indexing assigned by NLM MeSH Acute Disease; Antihypertensive Agents /economics /therapeutic use; Cost-Benefit Analysis; Double-Blind Method; Drug Therapy, Combination; Emergency Treatment; Esophageal and Gastric Varices /complications; Female; France; Gastrointestinal Hemorrhage /drug therapy /etiology /mortality; Humans; Intensive Care Units; Length of Stay; Liver Cirrhosis /complications; Lypressin /analogs & Male; Nitroglycerin

1999 NHS Economic Evaluation Database.

749. How do you approach a patient with Pneumomediastinum?

, the mechanism behind ecstasy associated pneumomediastinum is unclear. It perhaps is related to alveoli rupture. Boerhaave’s Syndrome is esophageal rupture, most common in the distal left posterior esophogus Pneumomediastinum in the setting of vomiting requires a contrast esophogram to rule out Boerhaave’s spontaneous pneumomediastinum is usually self limited. Rare associated complications include tension pneumomediastinum, pneumothorax or pneumopericardium. If pneumomediastinum is found in a patient

2006 Clinical Correlations Q&A

750. Plummer-Vinson syndrome

syndrome is unknown. The most important possible etiological factor is iron deficiency. Other possible factors include malnutrition, genetic predisposition or autoimmune processes. Management and treatment Plummer-Vinson syndrome can be treated effectively with iron supplementation and mechanical dilation. In case of significant obstruction of the esophageal lumen by esophageal web and persistent dysphagia despite iron supplementation, rupture and dilation of the web are necessary. Since Plummer-Vinson (...) of information on the Orphanet website are accepted. For all other comments, please send your remarks via . Only comments written in English can be processed. Check this box if you wish to receive a copy of your message * " for="captcha" >Please reproduce the text below: * Plummer-Vinson syndrome Disease definition Plummer-Vinson or Paterson-Kelly syndrome presents as a classical triad of dysphagia, iron-deficiency anemia and esophageal webs. ORPHA:54028 Classification level: Disorder Synonym(s): Kelly

2006 Orphanet

751. Secondary Prophylaxis of Gastrointestinal Bleeding in Cirrhotic Patients Using THALIDOMIDE

. It is defined by an increase in intrahepatic vascular resistance to portal venous inflow, with the subsequent development of collateral vessels, such as esophageal or gastric varices. As portal pressures rise over time, however, the resulting increase in variceal size and wall tension translates into an increasing likelihood of rupture and bleeding, leading to death in about 30% of patients. Over the last twenty years, data have emerged regarding the role of tumor necrosis factor (TNFα) in portal (...) discharge. Females of child-bearing potential will be seen weekly for the first month and must have a confirmed negative pregnancy test prior to being dispensed the next one week supply of study drug. After the first month, females of child-bearing potential will be seen every two weeks as will all other subjects. Standard follow-up medical care after esophageal variceal bleeding in patients who have undergone endoscopic therapy will include: follow-up endoscopy at regular intervals until variceal

2008 Clinical Trials

752. A Multi-Center, Randomized, Double-Blind, Parallel Group Study To Compare The Efficacy And Tolerability Of Valdecoxib And Diclofenac In Patients With A Sprained Ankle

Investigator must have thought that the patient required and was eligible for therapy with an anti-inflammatory agent and/or analgesic to control symptoms Exclusion Criteria: Women who were not post-menopausal or surgically sterilized, or who had have a positive urine pregnancy test prior to randomization and/or were not using adequate contraception according to the judgment of the Investigator Patients with a similar injury of the same joint within the last 6 months Clinical evidence of complete rupture (...) of ankle ligaments (third degree sprain), required bed rest, hospitalization, surgical intervention for the ankle injury or non-removable full cast, bilateral occurrence of ankle injury or ankle and knee injury on the same side Patients with esophageal, gastric or duodenal ulcer within 30 days prior to randomization or had active GI or other disease that in the opinion of the investigator would preclude safe participation by the subject in the study. Contacts and Locations Go to Information from

2008 Clinical Trials

753. A 75 Year Old With Dyspnea a Case Report.Observational Study

Summary: Clinical Case report Of spontaneous esophageal perforation in a 75 year old man. He prsented with breathlessness and on investigation found to have esophageal perforation Condition or disease Esophageal Perforation Detailed Description: Boerhaave's syndrome represents a diagnostic dilemma for the physician. Boerhaave's syndrome is an uncommon condition where there is oesophageal rupture following forceful vomiting. We report a case of spontaneous rupture of the esophagus in 75-year-old male (...) for Study: Child, Adult, Older Adult Sexes Eligible for Study: Male Accepts Healthy Volunteers: No Criteria Inclusion Criteria: male with esophageal perforation man with COPD Exclusion Criteria: Iatrogenic perforation Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its identifier (NCT

2007 Clinical Trials

754. Long-term outcome after hepatitis B surface antigen seroclearance in patients with chronic hepatitis B. (Abstract)

was not related to liver disease, such as hepatocellular carcinoma, decompensated liver cirrhosis, and rupture of esophageal varices.Our results suggest that HBsAg seroclearance confers favorable long-term outcomes in patients without hepatocellular carcinoma or decompensated liver cirrhosis at the time of HBsAg seroclearance.

2006 American Journal of Medicine

755. Pneumoperitoneum Due to Gastric Perforation After Cardiopulmonary Resuscitation: Case Report. (Abstract)

after resuscitation revealed pneumoperitoneum without pneumomediastinum. The patient underwent laparotomy; a 6-cm perforation of the posterior gastric wall along the lesser curve was detected and repaired.Gastric perforation after cardiopulmonary resuscitation should be suspected when chest radiographs obtained after resuscitation show pneumo-peritoneum without pneumomediastinum. Prompt laparotomy allows detection of gastric perforations and decreases the morbidity associated with rupture (...) of a hollow organ. The incidence of gastric perforation after cardiopulmonary resuscitation may be decreased with early endotracheal intubation, avoidance of esophageal intubation, and expeditious placement of an orogastric tube.

2008 American Journal of Critical Care

756. Long-term Outcome of Operated and Unoperated Epiphrenic Diverticula. (Abstract)

Long-term Outcome of Operated and Unoperated Epiphrenic Diverticula. The natural history of esophageal epiphrenic diverticula (ED) is not entirely clear; the decision whether to operate or not is often based on the personal preference of the physician and patient. The aim of this study was to evaluate the long-term fate of operated and unoperated patients with ED.Clinical, radiological, and motility findings, and operative morbidity and long-term outcome of 41 patients with ED (January 1993 (...) to December 2005) were analyzed. All patients were reviewed at the outpatient clinic or interviewed over the phone. A symptom score was calculated using a standard questionnaire and subjective patient assessment. The radiological maximum diameter of the ED was measured.Twenty-two patients (12M:10F; median age, 60 years) were operated. One underwent surgery for spontaneous rupture of a large diverticulum. Operative mortality was nil; postoperative morbidity was 22.7%, the most severe complication being

2008 Journal of Gastrointestinal Surgery

757. Successful conservative management of benign gastro-bronchial fistula after intrathoracic esophagogastrostomy. (Abstract)

Successful conservative management of benign gastro-bronchial fistula after intrathoracic esophagogastrostomy. Benign gastro-bronchial fistula is a rare and devastating complication of esophagectomy with gastric replacement. The most likely cause is a leak from the esophagogastric anastomosis with subsequent mediastinal abscess and rupture into the posterior wall of the tracheobronchial tree. The clinical presentation includes cough upon swallowing, fever, and recurrent pneumonia. Early (...) surgical treatment is the standard of care. A unique case of chronic gastro-bronchial fistula is reported in this article. The patient, a 57-year-old woman, was referred from another hospital after 6 months of symptomatic therapy and total enteral nutrition. A self-expanding esophageal metal stent allowed exclusion of the fistula with symptom relief and return to oral alimentation.

2007 Annals of Thoracic Surgery

758. Surgery With or Without Hepatic Arterial Chemotherapy in Treating Patients With Liver Cancer

/mm^3 Hemoglobin > 8 g/dL Hepatic Bilirubin < 2 times upper limit of normal (ULN) ALT and AST < 4 times ULN Renal Creatinine normal Cardiovascular No severe heart disease No cardiac effusion Other No other malignant disease No high risk for esophageal varices rupture No allergy to fluorouracil or cisplatin PRIOR CONCURRENT THERAPY: Biologic therapy Not specified Chemotherapy No prior hepatic arterial chemotherapy No prior systemic chemotherapy for HCC Endocrine therapy Not specified Radiotherapy

2005 Clinical Trials

759. Efficacy and Safety Study of Bevacizumab and Erlotinib to Treat Primary Liver Cancer That Cannot be Removed By Surgery

-melanoma skin cancer or cervical dysplasia, within five years prior to protocol entry. History of ruptured Hepatocellular carcinoma (HCC) lesion, or HCC lesion with large necrotic areas seen on conventional imaging studies, as determined by the Principal Investigator. Abnormalities of the cornea based on history (eg dry eye syndrome, Sjogren's syndrome) or congenital abnormality (eg Fuch's dystrophy). Gastrointestinal disease resulting in an inability to take oral medication or a requirement (...) ) that is refractory to medical management. Patients may not have received any other investigational agents nor have received any systemic chemotherapy esophageal or gastric varices; evidence of hepatic cirrhosis and/or portal

2005 Clinical Trials

760. A Research Study to Test (2) Two Different Types of Feeding Tubes Used in the Intensive Care Unit

contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 18 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: all ICU patients requiring enteral nutrition Exclusion Criteria: coagulopathy, esophageal or gastric, surgery, varices, trauma, ulcer, structure, rupture Contacts and Locations Go to Information from the National

2005 Clinical Trials

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