How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

836 results for

Erythroderma

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Guidance for assessment of erythroderma in neonates and infants for the pediatric immunologist. (PubMed)

Guidance for assessment of erythroderma in neonates and infants for the pediatric immunologist. Neonatal and infantile erythroderma (NIE) represents the common clinical phenotype of heterogeneous diseases ranging from benign and transient skin conditions to fatal multiorgan disorders. NIE regularly demands a comprehensive diagnostic workup in a multiprofessional setting, especially if newborns and young infants with the disease develop a failure to thrive and concomitant infectious, neurologic

2019 Pediatric Allergy and Immunology

2. Novel DSP Spectrin 6 Region Variant Causes Neonatal Erythroderma, Failure to Thrive, Severe Herpes Simplex Infections and Brain Lesions. (PubMed)

Novel DSP Spectrin 6 Region Variant Causes Neonatal Erythroderma, Failure to Thrive, Severe Herpes Simplex Infections and Brain Lesions. Desmoplakin (DSP) and Desmoglein 1 (DSG1) variants result in skin barrier defects leading to erythroderma, palmoplantar keratoderma and variable [AQ4] other features. Some DSG1 variant carriers present with SAM syndrome (Severe dermatitis, multiple Allergies, Metabolic wasting) and a SAM-like phenotype has been reported in 4 subjects with different

Full Text available with Trip Pro

2019 Acta Dermato-Venereologica

3. Recessive mosaicism in ABCA12 causes blaschkoid congenital ichthyosiform erythroderma. (PubMed)

Recessive mosaicism in ABCA12 causes blaschkoid congenital ichthyosiform erythroderma. We report an unique case of a three-year-old girl who presents with linear erythematosquamous lesions following the lines of Blaschko, suggestive of genetic mosaicism in the skin. Single candidate gene analyses were performed on DNA from blood, excluding Conradi-Hünermann Happle syndrome, erythrokeratodermia variabilis and a mosaic presentation of pityriasis rubra pilaris. With whole exome sequencing (WES

2019 British Journal of Dermatology

4. TP53 alterations in primary and secondary Sézary syndrome: A diagnostic tool for the assessment of malignancy in patients with erythroderma. (PubMed)

TP53 alterations in primary and secondary Sézary syndrome: A diagnostic tool for the assessment of malignancy in patients with erythroderma. Recent massive parallel sequencing data have evidenced the genetic diversity and complexity of Sézary syndrome mutational landscape with TP53 alterations being the most prevalent genetic abnormality. We analyzed a cohort of 35 patients with SS and a control group of 8 patients with chronic inflammatory dermatoses. TP53 status was analyzed at different (...) method for the diagnosis of patients with erythroderma as patients with inflammatory dermatoses did not display TP53 alteration.

Full Text available with Trip Pro

2017 PLoS ONE

5. Erythroderma: A Rare Complication of Dyshidrotic Eczema (PubMed)

Erythroderma: A Rare Complication of Dyshidrotic Eczema A 47-year-old man with a history of dyshidrotic eczema presented to the emergency department with diffuse erythema, chills and pruritus of three weeks' duration. The patient had received two injections of methotrexate in the preceding two weeks, both of which had failed to improve his whole-body erythema and pruritus. In the emergency department, the patient was evaluated for infection and admitted for the dermatology consultation. After (...) being seen on the general medical floor by the dermatology service the diagnosis of erythroderma was made and the patient was treated with intravenous (IV) cyclosporine therapy, with which his rash dramatically improved over three days. This case report summarizes the presentation and differential of erythroderma, and highlights the importance of having a high index of suspicion for this potentially fatal disease.

Full Text available with Trip Pro

2018 Cureus

6. Hydroxychloroquine-Induced Psoriasis-form Erythroderma in a Patient with Systemic Lupus Erythematosus (PubMed)

Hydroxychloroquine-Induced Psoriasis-form Erythroderma in a Patient with Systemic Lupus Erythematosus 30058593 2018 12 11 2018 12 11 2542-5641 131 15 2018 Aug 05 Chinese medical journal Chin. Med. J. Hydroxychloroquine-Induced Psoriasis-form Erythroderma in a Patient with Systemic Lupus Erythematosus. 1887-1888 10.4103/0366-6999.237411 Wang Wen-Ming WM Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing

Full Text available with Trip Pro

2018 Chinese medical journal

7. Juvenile Open Angle Glaucoma with Non Bullous Congenital Ichthyosiform Erythroderma. (PubMed)

Juvenile Open Angle Glaucoma with Non Bullous Congenital Ichthyosiform Erythroderma. Glaucoma in patients with nonbullous congenital ichthyosiform erythroderma (NBCIE) is a rare entity that has not been described in a histologically confirmed case. We present a unique case of coexisting glaucoma, ichthyosis, and dwarfism that has not been previously described.We present a case of NBCIE with glaucoma and dwarfism that presented to our outpatient department. The patient was referred for watering

2018 Journal of Glaucoma

8. Topical Hypochlorite and Skin Acidification Improves Erythroderma of Omenn Syndrome. (PubMed)

Topical Hypochlorite and Skin Acidification Improves Erythroderma of Omenn Syndrome. We describe a case of Omenn syndrome displaying exudative erythroderma and other characteristic features, including alopecia, absent B and naïve T cells, hyper immunoglobulin E levels, and eosinophilia. A pathogenic recombination-activating RAG1 homozygous genetic mutation confirmed the diagnosis. She required frequent antibiotics at both treatment and prophylactic doses, which alone did not control her (...) erythroderma, but her high risk of infection precluded the use of systemic agents such as cyclosporine, which would further suppress her already severely compromised immune system. Thrice-weekly topical dilute hypochlorite compresses, combined with skin acidification with a low pH emollient, were initiated to control inflammation and for cutaneous bacterial prophylaxis. She demonstrated a marked improvement in her erythroderma within days after treatment initiation. Further improvement continued

Full Text available with Trip Pro

2018 Pediatrics

9. Pityriasis rubra pilaris-like erythroderma secondary to phosphoinositide 3-kinase inhibition. (PubMed)

Pityriasis rubra pilaris-like erythroderma secondary to phosphoinositide 3-kinase inhibition. Phosphoinositide 3-kinase (PI3K) inhibitors are a class of small-molecule inhibitors approved for the treatment of certain leukaemias and lymphomas. Their dermatological adverse event profile is poorly described.To characterize a rare cutaneous adverse event from PI3K inhibitors in order to help dermatologists and oncologists identify and effectively manage such eruptions.This was a retrospective (...) analysis of patients receiving PI3K inhibitors referred to the Skin Toxicities Program in The Center for Cutaneous Oncology.Three patients on PI3K inhibitors for treatment of malignancy developed diffuse erythroderma and keratoderma. Clinical and histopathological findings were consistent with pityriasis rubra pilaris (PRP)-like reactions. All patients improved with topical and oral corticosteroids, oral acitretin, and drug discontinuation.PRP-like cutaneous eruptions may develop secondary to PI3K

2018 Clinical & Experimental Dermatology

10. Chronic idiopathic erythroderma of elderly men is an independent entity that has a distinct TARC/IgE profile from adult atopic dermatitis. (PubMed)

Chronic idiopathic erythroderma of elderly men is an independent entity that has a distinct TARC/IgE profile from adult atopic dermatitis. Although there are several diseases that cause erythroderma, patients are often encountered with erythroderma of unknown cause which persists for a long time. The aim of this study was to characterize this chronic idiopathic erythroderma (CIE).Adult patients with CIE, atopic dermatitis (AD), psoriatic erythroderma (PsE), or generalized drug eruption (DE (...) ), who visited Fukuoka University Hospital Dermatology Department from 2010 to 2015, were enrolled. Their clinical and laboratory data were extracted from the patient database. CIE was defined as erythroderma without any apparent cause and lasting more than 3 months.Twenty-three CIE, 82 AD, 39 psoriatic erythroderma, and 99 drug eruption cases were enrolled. The mean age of CIE patients was 74.7 ± 8.8, and the male : female ratio was 21 : 2. Laboratory data for CIE and AD were similar, but serum

2018 International Journal of Dermatology

11. Acute Erythroderma in a Patient Receiving TNF-α-Blocking Therapy for Hidradenitis Suppurativa (PubMed)

Acute Erythroderma in a Patient Receiving TNF-α-Blocking Therapy for Hidradenitis Suppurativa Tumor necrosis factor-α (TNF-α) normally binds to TNF-α receptors, leading to the inflammatory response of autoimmune diseases. Adalimumab is a TNF-inhibiting, anti-inflammatory, biological medication which binds to TNF-α, thus reducing this inflammatory response. The use of TNF-α-inhibiting medication, such as adalimumab, being the first FDA-approved treatment for hidradenitis suppurativa, has (...) drastically changed the management of dermatological diseases. One rarely reported manifestation that occurs as a side effect associated with the use of TNF-α-blocking agents is erythroderma. This study, for the first time, reports the case of a patient suffering from hidradenitis suppurativa with concomitant psoriasis, who developed a severe and acute erythrodermic rash after the start of adalimumab therapy.

Full Text available with Trip Pro

2018 Case reports in dermatology

12. Hypersensitivity to orthopaedic implant manifested as erythroderma: Timing of implant removal (PubMed)

Hypersensitivity to orthopaedic implant manifested as erythroderma: Timing of implant removal Incidence of hypersensitivity to orthopaedic implant, once estimated in less than 1% of population, recently has increased to 10%. Controversies about the timing of implant removal remain, especially due to the fact that implant hypersensitivity may be a contributing factor to implant failure. We present a case report and literature reviews to establish the decision making for the timing of implant (...) removal in the presence of implant hypersensitivity.Female, 42 years old with nonunion of mid-shaft tibia and fibula which was treated with ORIF with conventional SAE16 stainless steel plate and bone graft. A week after, she developed a generalized rash, which is later diagnosed as erythroderma, that relapsed despite adequate systemic corticosteroid. Poor healing of surgical site wound were marked. After the implant removal, the cutaneous condition improved and no relapse were found.Management

Full Text available with Trip Pro

2018 International journal of surgery case reports

13. Pityriasis rubra pilaris–like erythroderma in the setting of pembrolizumab therapy responsive to acitretin (PubMed)

Pityriasis rubra pilaris–like erythroderma in the setting of pembrolizumab therapy responsive to acitretin 30112450 2019 02 26 2352-5126 4 7 2018 Aug JAAD case reports JAAD Case Rep Pityriasis rubra pilaris-like erythroderma in the setting of pembrolizumab therapy responsive to acitretin. 669-671 10.1016/j.jdcr.2018.06.022 Coleman Emily E Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut. Panse Gauri G Department of Dermatology, Yale University School

Full Text available with Trip Pro

2018 JAAD Case Reports

14. Metastatic pulmonary melanoma complicated with erythroderma and recurrent sepsis (PubMed)

Metastatic pulmonary melanoma complicated with erythroderma and recurrent sepsis Erythroderma is occasionally associated with lung cancer. Here we report a 69-year-old male who has history of melanoma from 8 years ago presented with erythroderma associated with skin, soft tissue and pulmonary infection. CT chest showed a single enlarging right upper lobe lung nodule. Biopsy showed evidence of adenocarcinoma, and eventually proven to be metastatic melanoma. The patient improved after antibiotics (...) and antifungal treatment. To our knowledge, this is the first case of melanoma metastasis presented as erythroderma as paraneoplastic syndrome.

Full Text available with Trip Pro

2018 Respiratory Medicine Case Reports

15. Erythroderma and extensive poikiloderma – a rare initial presentation of dermatomyositis: a case report (PubMed)

Erythroderma and extensive poikiloderma – a rare initial presentation of dermatomyositis: a case report Dermatomyositis is a humoral-mediated inflammatory myopathy with symmetrical proximal muscle weakness and dermatological manifestations such as Gottron's papules, heliotrope rash, periungual abnormalities, and flagellate erythema. Erythroderma is a severe and potentially life-threatening dermatological condition with diffuse erythema and scaling involving more than 90% of the skin surface (...) area. Poikiloderma vasculare atrophicans refers to mottled hyperpigmentation and hypopigmentation of the skin with in-between telangiectases and areas of atrophy and is considered a variant of mycosis fungoides. Poikilodermatomyositis is the term given to the condition with poikiloderma and inflammatory myopathy. Only a few cases are reported on erythroderma in dermatomyositis and poikilodermatomyositis. Erythrodermal pattern of dermatomyositis transforming into poikilodermatomyositis

Full Text available with Trip Pro

2018 Journal of medical case reports

16. A case report of erythroderma in a patient with borderline leprosy on reversal reaction: a result of the exacerbated reaction? (PubMed)

A case report of erythroderma in a patient with borderline leprosy on reversal reaction: a result of the exacerbated reaction? Erythroderma is characterized by erythema and scaling affecting more than 90% of the body surface area. Inflammatory, neoplastic and, more rarely, infectious diseases may culminate with erythroderma. Diagnosis of the underlying disorder is therefore crucial to institute the appropriate therapy. Leprosy is a chronic infectious disease that is endemic in Brazil. Here we (...) present an unusual case of leprosy and reversal reaction causing erythroderma, and we discuss the underlying immunological mechanisms which could contribute to the generalized skin inflammation.We report a case of a patient with reversal reaction (RR) in borderline borderline leprosy presenting with erythroderma and neural disabilities. Histopathology of the skin showed regular acanthosis and spongiosis in the epidermis and, in the dermis, compact epithelioid granulomas as well as grouped and isolated

Full Text available with Trip Pro

2017 BMC Dermatology

17. Graft-versus-host disease-like erythroderma: a sign of recurrent thymoma: A case report. (PubMed)

Graft-versus-host disease-like erythroderma: a sign of recurrent thymoma: A case report. Thymomas are associated with numerous autoimmune disorders, such as myasthenia gravis (MG), pure red cell aplasia (PRCA), and systemic lupus erythematosus (SLE). However, graft-versus-host disease (GVHD)-like erythroderma is a relatively uncommon paraneoplastic disorder associated with thymomas and signifies a poor prognosis.A 35-year-old woman with medical history significant for stage IVa type AB thymoma (...) as corticosteroids.The eruptions gradually subsided with hyperpigmentation; however the patient eventually died of multiple organ failure.GVHD-like erythroderma is an uncommon paraneoplastic disorder associated with thymomas. Though its pathogenesis still needs further research, prompt diagnosis and appropriate treatment can improve survival rate in patients.

Full Text available with Trip Pro

2017 Medicine

18. Is Neutrophilic Desquamative Erythroderma a Form of Acute Generalized Exanthematous Pustulosis? (PubMed)

Is Neutrophilic Desquamative Erythroderma a Form of Acute Generalized Exanthematous Pustulosis? 29224230 2018 06 07 1468-3083 32 6 2018 Jun Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Is neutrophilic desquamative erythroderma a form of acute generalized exanthematous pustulosis? e230-e232 10.1111/jdv.14751 Weins A B AB http://orcid.org/0000-0002-0982-7122 Department of Dermatology and Allergy Biederstein, Technical University of Munich

2017 Journal of the European Academy of Dermatology and Venereology

19. The role of histological presentation in erythroderma. (PubMed)

The role of histological presentation in erythroderma. Erythroderma is a serious medical condition characterized by inflamed red skin involving over 90% of the body. It can be the common presentation of different diseases, therefore clinical diagnosis can be problematic. Controversial data are reported regarding the diagnostic value of histological examination in erythroderma subjects.A retrospective study was performed, investigating histological skin specimens of patients with a clinical (...) diagnosis of erythroderma admitted to the Department of Dermatology of State Pediatric Medical University, Saint Petersburg, from 2001 to 2014. Histopathology examination was performed in each case by a pathologist with a special interest in the skin disease who was blind to any clinical information as well as to final diagnosis.Blinded histopathology examination alone was able to give the correct diagnosis in 61% (n = 50/82) of cases when compared to final diagnosis. A diagnosis of psoriasis was made

2017 International Journal of Dermatology

20. Infective endocarditis following tumor necrosis factor-α antagonist therapy for management of psoriatic erythroderma: a case report (PubMed)

Infective endocarditis following tumor necrosis factor-α antagonist therapy for management of psoriatic erythroderma: a case report The introduction of biological agents, such as infliximab, which act against tumor necrosis factor-α was a major advance for the treatment of an increasing number of chronic diseases. Tumor necrosis factor-α antagonists represent a major therapeutic advance for the management of chronic inflammatory diseases, such as psoriasis. Previous studies have reported (...) that the use of tumor necrosis factor-α antagonists increased the risk of opportunistic infections and reactivation of latent bacterial infections. Cardiac involvement, such as infective endocarditis, is very rare in the literature.A 77-year-old Asian man with a 10-year history of psoriatic erythroderma was referred due to high fever and general malaise. He was treated with Predonine (prednisolone) and infliximab. After treatment, cardiac echography showed mitral valve vegetation and brain magnetic

Full Text available with Trip Pro

2017 Journal of medical case reports

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>