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Erythema Chronicum Migrans

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1. Erythema Chronicum Migrans

Erythema Chronicum Migrans Erythema Chronicum Migrans Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Erythema Chronicum Migrans (...) Erythema Chronicum Migrans Aka: Erythema Chronicum Migrans , Erythema Migrans II. Definition Pathognomonic bullseye rash of early III. Epidemiology Now thought to occur in 90% of cases Previously thought to be seen in only 50-60% Lower detection due to ECM rash that is missed Reinforces need for very careful skin exam Appears in 86-100% of symptomatic cases IV. Timing Occurs 3-30 days (median 7 days) after deer V. Distribution Localized rash at deer site VI. Appearance Initial Small red painless

2018 FP Notebook

2. Comparison of Doxycycline and Cefuroxime Axetil in Erythema Migrans

developed or intensified since the onset of erythema migrans or since the date of enrollment for controls were referred to as "new or increased symptoms"(NOIS). Condition or disease Intervention/treatment Phase Erythema Chronicum Migrans Drug: doxycycline Drug: Cefuroxime Axetil 500Mg Tab Other: control subjects Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Enrollment : 509 participants Allocation: Non-Randomized Intervention Model (...) terms Erythema Erythema Chronicum Migrans Glossitis, Benign Migratory Skin Diseases Skin Manifestations Signs and Symptoms Lyme Disease Borrelia Infections Gram-Negative Bacterial Infections Bacterial Infections Tick-Borne Diseases Skin Diseases, Bacterial Spirochaetales Infections Skin Diseases, Infectious Infection Glossitis Tongue Diseases Mouth Diseases Stomatognathic Diseases Doxycycline Cefuroxime Cefuroxime axetil Anti-Bacterial Agents Anti-Infective Agents Antimalarials Antiprotozoal Agents

2018 Clinical Trials

3. Erythema chronicum migrans: a possibly infectious disease imported from Northern Europe. Full Text available with Trip Pro

Erythema chronicum migrans: a possibly infectious disease imported from Northern Europe. 936603 1976 09 01 2018 11 13 0093-0415 124 6 1976 Jun The Western journal of medicine West. J. Med. Erythema chronicum migrans: a possibly infectious disease imported from Northern Europe. 503-5 Wagner L L Susens G G Heiss L L Ganz R R McGinley J J eng Case Reports Journal Article United States West J Med 0410504 0093-0415 IM Cerebrospinal Fluid analysis Chronic Disease Erythema complications diagnosis

1976 Western Journal of Medicine

4. Erythema chronicum migrans in Britain. Full Text available with Trip Pro

Erythema chronicum migrans in Britain. 709235 1979 01 26 2016 11 23 0007-1447 2 6144 1978 Oct 14 British medical journal Br Med J Erythema chronicum migrans in Britain. 1087 Goldin D D Champion R H RH Rook A A Roberts S O SO eng Letter England Br Med J 0372673 0007-1447 AIM IM Animals Arachnid Vectors Chronic Disease Erythema epidemiology transmission Humans Ticks United Kingdom 1978 10 14 1978 10 14 0 1 1978 10 14 0 0 ppublish 709235 PMC1608178

1978 British medical journal

5. Erythema Migrans in Elderly

Ljubljana ClinicalTrials.gov Identifier: Other Study ID Numbers: EM-elderly First Posted: December 13, 2017 Last Update Posted: August 14, 2018 Last Verified: August 2018 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Additional relevant MeSH terms: Layout table for MeSH terms Erythema Lyme Disease Erythema Chronicum Migrans Glossitis (...) Erythema Migrans in Elderly Erythema Migrans in Elderly - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Erythema Migrans in Elderly The safety and scientific validity of this study is the responsibility

2017 Clinical Trials

6. Erythema Chronicum Migrans

Erythema Chronicum Migrans Erythema Chronicum Migrans Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Erythema Chronicum Migrans (...) Erythema Chronicum Migrans Aka: Erythema Chronicum Migrans , Erythema Migrans II. Definition Pathognomonic bullseye rash of early III. Epidemiology Now thought to occur in 90% of cases Previously thought to be seen in only 50-60% Lower detection due to ECM rash that is missed Reinforces need for very careful skin exam Appears in 86-100% of symptomatic cases IV. Timing Occurs 3-30 days (median 7 days) after deer V. Distribution Localized rash at deer site VI. Appearance Initial Small red painless

2015 FP Notebook

7. Vesiculobullous and hemorrhagic erythema migrans: uncommon variants of a common disease. (Abstract)

Vesiculobullous and hemorrhagic erythema migrans: uncommon variants of a common disease. The diagnosis of Lyme disease relies on the accurate diagnosis of erythema chronicum migrans (ECM) because serologic tests, culture, and polymerase chain reactions are often inaccurate. Although ECM is classically associated with a targetoid rash, there are many variants of this lesion. These variants of ECM are often initially diagnosed as cellulitis or spider bite reactions and treated with oral

2015 International Journal of Dermatology

8. Cytokines and Chemokines in Erythema Migrans

borreliosis inflammation outcome Additional relevant MeSH terms: Layout table for MeSH terms Erythema Erythema Chronicum Migrans Glossitis, Benign Migratory Skin Diseases Skin Manifestations Signs and Symptoms Lyme Disease Borrelia Infections Gram-Negative Bacterial Infections Bacterial Infections Tick-Borne Diseases Skin Diseases, Bacterial Spirochaetales Infections Skin Diseases, Infectious Infection Glossitis Tongue Diseases Mouth Diseases Stomatognathic Diseases Anti-Bacterial Agents Antibiotics (...) Cytokines and Chemokines in Erythema Migrans Cytokines and Chemokines in Erythema Migrans - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Cytokines and Chemokines in Erythema Migrans The safety

2013 Clinical Trials

9. Erythema Annulare Centrifugum (Overview)

for erythema marginatum rheumaticum, erythema chronicum migrans, and erythema gyratum repens. When taken in this broad sense, EAC can be scaly or nonscaly, pruritic or nonpruritic, and rarely vesicular. Other Medscape erythema articles include the following: Next: Pathophysiology The pathogenesis of erythema annulare centrifugum (EAC) is unknown, but it is probably due to a hypersensitivity reaction to a variety of agents, including drugs, arthropod bites, infections (bacterial, mycobacterial, viral (...) Erythema Annulare Centrifugum (Overview) Erythema Annulare Centrifugum: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEyMjcwMS1vdmVydmlldw== processing > Erythema Annulare

2014 eMedicine.com

10. Erythema Annulare Centrifugum (Diagnosis)

for erythema marginatum rheumaticum, erythema chronicum migrans, and erythema gyratum repens. When taken in this broad sense, EAC can be scaly or nonscaly, pruritic or nonpruritic, and rarely vesicular. Other Medscape erythema articles include the following: Next: Pathophysiology The pathogenesis of erythema annulare centrifugum (EAC) is unknown, but it is probably due to a hypersensitivity reaction to a variety of agents, including drugs, arthropod bites, infections (bacterial, mycobacterial, viral (...) Erythema Annulare Centrifugum (Diagnosis) Erythema Annulare Centrifugum: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTEyMjcwMS1vdmVydmlldw== processing > Erythema Annulare

2014 eMedicine.com

11. Doxycycline in Therapy of Erythema Migrans

24, 2016 Last Verified: March 2016 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Keywords provided by Franc Strle, University Medical Centre Ljubljana: Lyme borreliosis Erythema migrans Doxycycline Subjective symptoms Outcome Additional relevant MeSH terms: Layout table for MeSH terms Erythema Erythema Chronicum Migrans Glossitis, Benign Migratory Borrelia Infections Skin Diseases Skin Manifestations Signs and Symptoms Lyme Disease Gram-Negative Bacterial (...) Doxycycline in Therapy of Erythema Migrans Doxycycline in Therapy of Erythema Migrans - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Doxycycline in Therapy of Erythema Migrans The safety and scientific

2011 Clinical Trials

12. Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice

for revision of national guidelines. Condition or disease Intervention/treatment Phase Erythema Migrans Erythema Chronicum Migrans Borreliosis Lyme Disease Early Lyme Disease Drug: Doxycycline Drug: Phenoxymethylpenicillin Drug: Amoxicillin Phase 4 Detailed Description: Comparison of phenoxymethylpenicillin, doxycycline and amoxicillin for Erythema migrans in Norwegian general practice. Every patient receives 14 days of antibiotic treatment. There are blood samples for measurement of Borrelia antibody (...) Last Verified: December 2014 Keywords provided by Morten Lindbaek, University of Oslo: Antibiotics General Practice Erythema migrans Borrelia Ticks Additional relevant MeSH terms: Layout table for MeSH terms Erythema Lyme Disease Erythema Chronicum Migrans Glossitis, Benign Migratory Borrelia Infections Skin Diseases Skin Manifestations Signs and Symptoms Gram-Negative Bacterial Infections Bacterial Infections Tick-Borne Diseases Spirochaetales Infections Skin Diseases, Bacterial Skin Diseases

2011 Clinical Trials

13. Guidelines for the Prevention, Diagnosis, and Treatment of Lyme Disease

the administration of a single dose of oral doxycycline within 72 hours of tick removal over observation (strong recommendation, moderate-quality evidence). comment: 4 • cid 2020:XX (XX XXXX) • Lantos et al Doxycycline is given as a single oral dose, 200 mg for adults and 4.4 mg/kg (up to a maximum dose of 200 mg) for children. V. WHAT IS THE PREFERRED DIAGNOSTIC TESTING STRATEGY FOR ERYTHEMA MIGRANS? Recommendations: 1. In patients with potential tick exposure in a Lyme disease en- demic area who have 1 or more (...) skin lesions compatible with erythema migrans, we recommend clinical diagnosis rather than laboratory testing (strong recommendation, moderate quality evidence). 2. In patients with 1 or more skin lesions suggestive of, but atypical for erythema migrans, we suggest antibody testing performed on an acute-phase serum sample (followed by a convalescent-phase serum sample if the initial result is negative) rather than currently available direct detection methods such as polymerase chain reaction (PCR

2020 American Academy of Neurology

14. 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease

and treatment of Lyme disease presenting as erythema migrans, Lyme disease complicated by neurologic, cardiac, and rheumatologic manifestations, Eurasian manifestations of Lyme disease, and Lyme disease complicated by coinfection with other tick-borne pathogens. This guideline does not include comprehensive recommendations for babesiosis and tick-borne rickettsial infections, which are published in separate guidelines. The target audience for this guideline includes primary care physicians and specialists (...) STRATEGY FOR ERYTHEMA MIGRANS? Recommendations: In patients with potential tick exposure in a Lyme disease endemic area who have 1 or more skin lesions compatible with erythema migrans, we recommend clinical diagnosis rather than laboratory testing (strong recommendation, moderate quality evidence). In patients with 1 or more skin lesions suggestive of, but atypical for erythema migrans, we suggest antibody testing performed on an acute-phase serum sample (followed by a convalescent-phase serum sample

2020 Infectious Diseases Society of America

15. CRACKCast E137 – Skin Infections

infections, Erythema chronicum migrans Venous stasis Inflammation near a joint: Gout Pseudogout Septic arthritis Tenosynovitis Ruptured Baker’s cyst Traumatic joint effusion Hemarthrosis Autoimmune arthritis. [3] List 4 Antibiotics each that cover Group A Strep and Staph aureus Check out this recent JAMA article that supports the notion that MRSA coverage isn’t always required. See Rosens Table 129.1 and 129.2 Skin Infections: Bacteriology and First-Line Antibiotic Therapy AND First-Line Oral Antibiotics (...) -Clav Erythema migrans Borrelia burgdorferi Doxycycline Puncture wound through foot Pseudomomas aeruginosa Ciprofloxacin [1] List 6 risk factors for cellulitis From Uptodate: Predisposing factors for development of cellulitis and/or skin abscess include: Skin barrier disruption due to trauma (such as abrasion, penetrating wound, pressure ulcer, venous leg ulcer, insect bite, injection drug use) Skin inflammation (such as eczema, radiation therapy) Edema due to impaired lymphatic drainage Edema due

2017 CandiEM

16. CRACKCast E116 – Arthritis

Pulmonary Pleuritis, nodules RA Renal Renal crisis, ARF Scleroderma Skin Plaques on elbows, knees Psoriasis Sclerodactyly, calcinosis Scleroderma Erythema chronicum migrans Lyme disease Tophi Gout Erythema Marginatum Rheumatic fever Subcutaneous nodules RA *Excludes rheumatic vasculitis diseases. ARF, Acute rheumatic fever; IBD, inflammatory bowel disease; RA, Rheumatoid Arthritis Extraarticular manifestations of RA: Osteoporosis, atlantoaxial subluxation Muscle weakness, synovitis, myositis, myopathies (...) . This is what we use to diagnose acute rheumatic fever (ARF). ARF is a systemic disease triggered by a complex hyperimmune response in the weeks after group A streptococcal pharyngitis The Jones Criteria: Lab evidence of prior group A strep infection** Major (need 2 or more) Polyarthritis Carditis Chorea Erythema marginatum Subcutaneous nodules Minor (need 1 major and 2 minor) Arthralgia Fever Elevated ESR/CRP Long PR on ECG [7] What is erythema marginatum? See Figure 106.6. This is the pathognomonic rash

2017 CandiEM

17. Clinical and economic outcomes evaluated in Lyme disease: a systematic review Full Text available with Trip Pro

outcomes and cost estimates, this review only provided an assessment of the studies without a summary estimate from a meta-analysis. A literature search was conducted using EMBASE and PubMed, including studies published through 19 December 2018. The search terms included (((((“lyme*”[Title/Abstract]) OR “borrelia*”[Title/Abstract]) OR “erythema chronicum migrans*”[Title/Abstract]) OR “erythema migrans*”[Title/Abstract])) AND (((((cost*[Title/Abstract]) OR economic*[Title/Abstract]) OR budget*[Title (...) (amoxicillin, cefuroxime axetil) and oral tetracyclines (doxycycline) as effective first-line agents based on nine randomized, prospective studies where erythema migrans (an expanding red skin rash) was the disease-defining criterion and the resolution of symptoms the most common outcome [ ]. Other early manifestations of disease may include meningitis, carditis, arthritis, or neurological symptoms [ ]. While antibiotic treatment of early LD may improve the cutaneous symptoms and prevent other early

2020 Parasites & vectors

18. Pediatric Bilateral Facial Paralysis: An Unusual Presentation of Lyme Disease. (Abstract)

(infectious and neoplastic), brain stem encephalitis, Guillain-Barre syndrome, sarcoidosis, Lyme disease, human immunodeficiency virus infection, leukemia, and vasculitis. In the evaluation of a child who presents with bilateral FNP, history plays the utmost role in the diagnosis. A history of rash consistent with erythema chronicum migrans, recent tick exposure, or travel to a Lyme disease-endemic area is highly suggestive that the facial paralysis is a result of Lyme disease. It is also important

2018 Pediatric Emergency Care

19. Patient's Pretreatment Expectations About Post-Lyme Symptoms

Last Verified: January 2019 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Daša Stupica, University Medical Centre Ljubljana: Post-Lyme symptoms Pretreatment expectations Additional relevant MeSH terms: Layout table for MeSH terms Erythema Erythema Chronicum Migrans Glossitis, Benign Migratory Skin Diseases Skin Manifestations Signs and Symptoms Lyme Disease Borrelia Infections Gram-Negative (...) Ljubljana Information provided by (Responsible Party): Daša Stupica, University Medical Centre Ljubljana Study Details Study Description Go to Brief Summary: The investigators will focus on pretreatment expectations of patients with early Lyme disease manifested as erythema migrans with the aim of assessing the association between pretreatment expectations quantified with a questionnaire and treatment outcome quantified with the presence of post-Lyme symptoms. Furthermore, the investigators will compare

2018 Clinical Trials

20. Next Generation Sequencing Detection of Lyme Disease

terms Erythema Lyme Disease Communicable Diseases Infection Erythema Chronicum Migrans Glossitis, Benign Migratory Skin Diseases Skin Manifestations Signs and Symptoms Borrelia Infections Gram-Negative Bacterial Infections Bacterial Infections Tick-Borne Diseases Spirochaetales Infections Skin Diseases, Bacterial Skin Diseases, Infectious Glossitis Tongue Diseases Mouth Diseases Stomatognathic Diseases (...) testing. The investigators will then conduct basic descriptive statistics on the results to determine if NGS is capable of detecting Lyme DNA during the acute phase of infection. Condition or disease Lyme Disease Pediatric Infectious Disorder Erythema Migrans Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 30 participants Observational Model: Case-Control Time Perspective: Prospective Official Title: Next Generation Sequencing to Detect Borrelia

2018 Clinical Trials

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