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Episcleritis

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1. Ocular tissue distribution of betamethasone after anterior-episcleral, posterior-episcleral, and anterior-intrascleral placement of nonbiodegradable implants. (PubMed)

Ocular tissue distribution of betamethasone after anterior-episcleral, posterior-episcleral, and anterior-intrascleral placement of nonbiodegradable implants. To investigate the intraocular distribution of betamethasone (BM) after implantation of transscleral drug delivery devices at three different sites in the eye: anterior episclera, posterior episclera, and anterior intrasclera.Nonbiodegradable implants designed to release BM for at least 1 month were placed at three different sites (...) after anterior-intrascleral placement of the implants were highest in the vitreous and retina-choroid among the three sites. The concentrations of BM in the three different sections of retina-choroid, which were around the placement site, opposite the placement site and posterior pole, were also determined. The concentration of BM in the retina-choroid around the placement site was higher than that in other parts of the retina-choroid after anterior-episcleral and anterior-intrascleral placement

2017 Retina

2. Episcleral brachytherapy for retinoblastoma. (PubMed)

Episcleral brachytherapy for retinoblastoma. To report visual outcomes, survival outcomes and complications following episcleral brachytherapy (EB) for retinoblastoma.Retrospective review of retinoblastoma cases treated with EB in a single institution. Survival outcomes were analysed using the Kaplan-Meier method.Eleven tumours of 11 eyes were treated with either iodine-125 or ruthenium-106 EB with a mean apical dose of 44 Gy. The tumours were classified as group B in 5 (46%), C in 3 (27%) or D

2019 British Journal of Ophthalmology

3. Episcleral Venous Pressure and the Ocular Hypotensive Effects of Topical and Intracameral Prostaglandin Analogs. (PubMed)

Episcleral Venous Pressure and the Ocular Hypotensive Effects of Topical and Intracameral Prostaglandin Analogs. There is a limit beyond which increasing either the concentration of a prostaglandin analog (PGA) or its dosing frequency fails to produce increases in ocular hypotensive efficacy with topical dosing. Intracameral PGA dosing with a bimatoprost implant, however, does not exhibit the same intraocular pressure (IOP)-lowering plateau at studied concentrations and the maximum-achievable (...) ocular hypotensive effects are not yet known. This suggests that the bimatoprost intracameral implant may activate another mechanism of action in addition to the mechanism(s) activated by topical application. Episcleral venous pressure (EVP) is a key determinant of IOP, and experimental manipulation of the episcleral vasculature can change both EVP and IOP. The recent observation that topical and intracameral PGA drug delivery routes produce different patterns of conjunctival hyperemia suggested

2019 Journal of Glaucoma

4. Corneal ulceration and episcleritis associated with Wiskott–Aldrich syndrome (PubMed)

Corneal ulceration and episcleritis associated with Wiskott–Aldrich syndrome To present anterior segment ophthalmic manifestations of Wiskott-Aldrich syndrome (WAS), a rare X-linked primary immune-deficiency.A 15-year old male with WAS presented with multiple corneal ulcers of the left eye. Once resolved, this was followed by separate episodes of episcleritis in the left eye and corneal infiltrates of the right eye. Successful treatment included topical antibiotics and anti

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2016 American journal of ophthalmology case reports

5. Episcleritis

Episcleritis Episcleritis submit The College submit You're here: Episcleritis Episcleritis The CMGs are guidelines on the diagnosis and management of a range of common and rare, but important, eye conditions that present with varying frequency in primary and first contact care. Share options Please login to view the images or . Aetiology Idiopathic inflammation of the vascular connective tissue layer that lies between the sclera and conjunctiva Predisposing factors Up to one third of cases (...) (especially nodular variety) associated with systemic disorders, e.g. collagen vascular diseases rheumatoid arthritis systemic lupus erythematosus inflammatory bowel disease Also other conditions including gout, ocular rosacea (NB importance of careful history taking) Previous history of episcleritis Herpes Zoster Ophthalmicus Commonest in 4th or 5th decades Symptoms Acute onset Typically unilateral red eye, but bilateral in a quarter to a half of cases Mild ache or burning sensation Sometimes tender

2015 College of Optometrists

6. Bimatoprost sustained-release intracameral implant reduces episcleral venous pressure in dogs. (PubMed)

Bimatoprost sustained-release intracameral implant reduces episcleral venous pressure in dogs. To determine the effect of a bimatoprost sustained-release intracameral implant (Bimatoprost SR) on episcleral venous pressure (EVP) in normal dogs.Normotensive beagle dogs were randomized to receive Bimatoprost SR 30 μg (n = 7) or sham injection (needle insertion only, n = 7) in one eye on day 1. EVP was measured with an episcleral venomanometer through day 65. Episcleral aqueous outflow vessels were

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2018 Veterinary ophthalmology

7. Prior non-irradiative focal therapies do not compromise the efficacy of delayed episcleral plaque brachytherapy in retinoblastoma. (PubMed)

Prior non-irradiative focal therapies do not compromise the efficacy of delayed episcleral plaque brachytherapy in retinoblastoma. Non-irradiative local therapies have shown promise in delaying or supplanting external beam radiotherapy (EBRT) and enucleation in patients with retinoblastoma. We hypothesised that prior focal therapy does not compromise the efficacy of delayed episcleral plaque brachytherapy (epBRT).We performed an institutional review board-approved medical record review

2018 British Journal of Ophthalmology

8. Visual outcome after posterior uveal melanoma episcleral brachytherapy including radiobiological doses (PubMed)

Visual outcome after posterior uveal melanoma episcleral brachytherapy including radiobiological doses To assess the long-term influence of radiobiological doses in the evolution of visual acuity (VA) in patients with uveal melanoma treated by episcleral brachytherapy.Visual acuity was evaluated prospectively from a case series of 243 patients in 2016 treated with 125I. Data analysis was applied to trend VA outcome and find the accurate best-fit line. Biologically effective dose (BED

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2018 Journal of contemporary brachytherapy

9. Is this a worrisome red eye? Episcleritis in the primary care setting (PubMed)

Is this a worrisome red eye? Episcleritis in the primary care setting Episcleritis is the inflammation of the thin, loose, highly vascular connective tissue layer that lies between the conjunctiva and sclera. Incidence is less than 1/1000. It is more common in women and those between 40 and 50 years of age. Most cases are idiopathic. It is classified into simple and nodular. Most attacks resolve within 1-3 months. The nodular type tends to be more recurrent and painful. It presents with acute

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2018 Journal of community hospital internal medicine perspectives

10. Episcleral racemose hemangioma. (PubMed)

Episcleral racemose hemangioma. Racemose hemangioma is a rare, benign vascular malformation. In the episclera, it appears as dilated, tortuous blood vessels that pass from the fornix over the globe surface to the limbal area, without capillary architecture, and then loop backward into the fornix. Fluorescein angiogram reveals the vascular malformation with rapid flow and confirms the episcleral vessels to be large in caliber and with a curvilinear, twisted configuration. We report the case

2018 JAAPOS - Journal of the American Association for Pediatric Ophthalmology and Strabismus

11. Advanced glaucoma secondary to bilateral idiopathic dilated episcleral veins - a case report. (PubMed)

Advanced glaucoma secondary to bilateral idiopathic dilated episcleral veins - a case report. Idiopathic elevated episcleral venous pressure (IEEVP) or idiopathic dilated episcleral veins (IDEV) is a rare abnormality, and thus therapeutic treatment for this condition rarely is discussed. We report a case of a patient with bilateral glaucoma secondary to IDEV for whom intraocular pressures (IOPs) were controlled successfully by trabeculectomy.A 50 year-old female with a complaint of persistent (...) red eyes for over 30 years, presented with numerous tortuous and engorged episcleral vessels in both eyes (OU), open angles OU with spontaneous blood in Schlemm's canal 360 degrees bilaterally. Orbital color Doppler examination showed the superior ophthalmic veins to be of normal calibre, with no reversal of flow. Head MRI with contrast and cerebral angiography were negative for arteriovenous fistula. Coronary angiography, color Doppler echocardiography and chest radiographs were within normal

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2018 BMC Ophthalmology

12. A Novel Use of Trypan Blue During Canalicular Glaucoma Surgery to Identify Aqueous Outflow to Episcleral and Intrascleral Veins. (PubMed)

A Novel Use of Trypan Blue During Canalicular Glaucoma Surgery to Identify Aqueous Outflow to Episcleral and Intrascleral Veins. We describe a novel technique comprising the use of trypan blue to confirm aqueous outflow to collector channels and aqueous veins after goniotomy with the Kahook Dual Blade (New World Medical, Rancho Cucamonga, CA). Intraocular dyes have been safely used during ophthalmic surgery to evaluate the patency of the trabecular meshwork and collector channels. Further (...) , trypan blue has been safely used to stain the anterior capsule of the lens in cataract surgery, to enhance visualization for capsulorhexis; similarly, trypan blue has been safely used to stain the trabecular meshwork for enhanced visualization during glaucoma angle surgery. Channelography enables evaluation of the collector channels during canaloplasty with fluorescein dye; episcleral fluid wave enables evaluation of the intraoperative structural patency of the conventional outflow system, from

2018 Journal of Glaucoma

13. Episcleral Venous Fluid Wave in the Living Human Eye Adjacent to Microinvasive Glaucoma Surgery (MIGS) Supports Laboratory Research: Outflow is Limited Circumferentially, Conserved Distally, and Favored Inferonasally. (PubMed)

Episcleral Venous Fluid Wave in the Living Human Eye Adjacent to Microinvasive Glaucoma Surgery (MIGS) Supports Laboratory Research: Outflow is Limited Circumferentially, Conserved Distally, and Favored Inferonasally. The purpose of this study was to describe downstream patterns of outflow with the episcleral venous fluid wave (EVFW) in the living human eye adjacent to microinvasive glaucoma surgery (MIGS) and determine if the EVFW supports existing ex-vivo laboratory outflow (...) research.Retrospective, noncomparative case series.A total of 10 eyes of 10 patients who underwent phaco-Trabectome and 10 eyes of 10 patients who underwent phaco-iStent consecutively at Glaucoma Associates of Texas for cataract and uncontrolled glaucoma who demonstrated an episcleral wave.The EVFW was visualized and recorded during irrigation and aspiration. To describe the hydrodynamic properties of the fluid wave, its degrees, extent, and characteristics were measured with a protractor in Photoshop.The incised

2018 Journal of Glaucoma

14. Episcleral Venous Outflow: A Potential Outcome Marker for iStent Surgery. (PubMed)

Episcleral Venous Outflow: A Potential Outcome Marker for iStent Surgery. (1) To propose the use of episcleral venous outflow (EVO) as an outcome marker of iStent surgery, and an EVO grading scale. (2) To determine the association of EVO with: (a) postoperative intraocular pressure (IOP) and medication burden; (b) iStent patency status.Retrospective cohort study including 151 glaucomatous eyes having undergone iStent-phacoemulsification surgery. Demographic and preoperative data (IOP, number

2017 Journal of Glaucoma

15. Impact of Video Technology for Improving Success of Medial Canthus Episcleral Anesthesia in Ophthalmology. (PubMed)

Impact of Video Technology for Improving Success of Medial Canthus Episcleral Anesthesia in Ophthalmology. Efficient learning of regional anesthesia in ophthalmology remains challenging because trainees are afforded limited opportunity to practice ocular anesthesia. The aim of this prospective, randomized, blinded study was to determine whether teaching with video improves regional anesthesia skills of residents in ophthalmology.From January to October 2016, 32 novice anesthesiology residents (...) were evaluated while performing medial canthus episcleral procedures during a 5-day rotation. Residents were randomly assigned to either receive or not receive a video review of their performance at day 3. The primary outcome was a comparison of akinesia using a 12-point scale before incision assessed by the blinded surgeon.A total of 288 blocks were performed by 32 residents and were assessed by 3 surgeons before the intervention (144 blocks) and after the intervention (144 blocks). Residents

2017 Regional Anesthesia and Pain Medicine

16. Establishment and Characterization of an Acute Model of Ocular Hypertension by Laser-Induced Occlusion of Episcleral Veins. (PubMed)

Establishment and Characterization of an Acute Model of Ocular Hypertension by Laser-Induced Occlusion of Episcleral Veins. This study was designed to develop and characterize a laser-induced model of acute intraocular hypertension that permits the study of the anterior segment of the eye.CD1 mice aged 5 and 8 weeks were examined for elevation of IOP induced by laser photocoagulation. We compared between occlusion of episcleral veins alone and when combined with 270° limbal vessel occlusion (...) and the density of RGCs were both significantly reduced after single or combined treatment.Laser photocoagulation of episcleral veins alone in CD1 mice aged 5 to 8 weeks may be used to induce ocular hypertension resulting in RNFL thinning and ganglion cell loss. This model permits the study of the anterior as well as the posterior segment of the eye.

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2017 Investigative Ophthalmology & Visual Science

17. Pattern of Local Recurrence After I-125 Episcleral Brachytherapy for Uveal Melanoma in a Spanish Referral Ocular Oncology Unit. (PubMed)

Pattern of Local Recurrence After I-125 Episcleral Brachytherapy for Uveal Melanoma in a Spanish Referral Ocular Oncology Unit. To describe the time, frequency, and clinical characteristics of treatment failure after I-125 brachytherapy in patients with uveal melanoma treated and followed in a Spanish referral ocular oncology unit.Prospective, consecutive, interventional case series.Patients diagnosed with uveal melanoma from 1995 to 2016 and treated with episcleral brachytherapy were included

2017 American Journal of Ophthalmology

18. Local Failure after Episcleral Brachytherapy for Posterior Uveal Melanoma: Patterns, Risk Factors and Management. (PubMed)

Local Failure after Episcleral Brachytherapy for Posterior Uveal Melanoma: Patterns, Risk Factors and Management. To evaluate the patterns, the risk factors, and the management of recurrence following brachytherapy in patients with posterior uveal melanoma, given that an understanding of the recurrence patterns can improve early recognition and management of local treatment failure in such patients.Retrospective cohort study.Setting: Multispecialty tertiary care center.A total of 375 eyes (...) treated with episcleral brachytherapy for posterior uveal melanoma from January 2004 to December 2014. Exclusion criteria included inadequate follow-up (<1 year) and previous radiation therapy. Main Outcomes and Measures: Local control rate and time to recurrence were the primary endpoints. Kaplan-Meier estimation and Cox proportional hazards models were conducted to identify risk factors for recurrence.Twenty-one patients (5.6%) experienced recurrence (follow-up range 12-156 months; median 47 months

2017 American Journal of Ophthalmology

19. An OCT Study of Anterior Nodular Episcleritis and Scleritis (PubMed)

An OCT Study of Anterior Nodular Episcleritis and Scleritis Anterior scleritis and episcleritis are a well-known presentation in tuberculosis. The case of a female patient with presumed tuberculous anterior scleritis and episcleritis is discussed in this article. Anterior segment OCT was efficient in diagnosis and evaluation of the therapeutic outcome. Antituberculosis chemotherapy was sufficient to achieve clinical remission.

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2017 Case reports in ophthalmological medicine

20. Bilaterally dilated episcleral vessels in patients with heritable pulmonary arterial hypertension (PubMed)

Bilaterally dilated episcleral vessels in patients with heritable pulmonary arterial hypertension 29264093 2019 01 18 2189-6577 18 6 2017 12 Journal of general and family medicine J Gen Fam Med Bilaterally dilated episcleral vessels in patients with heritable pulmonary arterial hypertension. 464-465 10.1002/jgf2.89 Watanabe Meri M Department of Ophthalmology Jichi Medical University Shimotsuke Japan. Makino Shinji S 0000-0002-0732-3254 Department of Ophthalmology Jichi Medical University (...) Shimotsuke Japan. Obata Hiroto H Department of Ophthalmology Jichi Medical University Shimotsuke Japan. eng Journal Article 2017 06 01 Japan J Gen Fam Med 101689875 2189-7948 episcleral vessel heritable pulmonary arterial hypertension intraocular pressure 2017 02 20 2017 04 18 2017 12 22 6 0 2017 12 22 6 0 2017 12 22 6 1 epublish 29264093 10.1002/jgf2.89 JGF289 PMC5729320 Retina. 2001;21(1):34-9 11217927 Br J Ophthalmol. 2012 Mar;96(3):459-60, 469 22049487

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2017 Journal of General and Family Medicine

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