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190 results for

Eosinophilic Cellulitis

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161. Conjunctivitis (Overview)

. Vernal disease is often associated with shield corneal ulcers. Perilimbal accumulation of eosinophils (Horner-Trantas dots) typifies vernal disease. Vernal keratoconjunctivitis (VKC), usually affects young boys, tends to be bilateral, and occurs in warm weather. VKC is presumed to be a hypersensitivity to exogenous antigens and may be associated with or accompanied by keratoconus. Preauricular adenopathy is absent; chemosis is common. The conjunctival discharge amount is moderate, stringy, or sparse (...) and/or available. Risk of chlamydial pneumonia exists. Pneumonia can occur in 10-20% of infants with chlamydial conjunctivitis as many as 6 months later. Untreated chlamydial conjunctivitis in adults can lead to conjunctival scarring. Any of the bacterial organisms that cause conjunctivitis, particularly in a premature infant, can lead to sepsis and death. Neonates are at risk for secondary meningitis, cellulitis, and septicemia, particularly if the conjunctivitis is caused by Escherichia coli, Staphylococcus

2014 eMedicine Emergency Medicine

162. Investigation of Otelixizumab in New-Onset, Autoimmune Type 1 Diabetes Mellitus Patients

concentration, Neutrophils, Lymphocytes, Monocytes, Eosinophils, and Basophils ABNORMAL CLINICAL CHEMISTRY PARAMETERS [ Time Frame: Day-1 to Month 24 ] Clinical chemistry parameters include; blood urea nitrogen, creatinine, fasting glucose, sodium, potassium, chloride, total carbondioxide, calcium, alanine transaminase, aspartate transaminase, Gamma-glutamyltransferase, Alkaline phosphatase, Total and direct bilirubin, uric acid, albumin, and total protein ABNORMAL ECG CHANGES [ Time Frame: Day-1 to Month (...) . The subject has received immunizationion with a vaccine within 4 weeks before the first dose of study drug or requires a vaccine within 30 days after the last dose of study drug The subject has had significant systemic infection during the 6 weeks before the first dose of study drug (e.g., infection requiring hospitalization, major surgery, or intravenous (i.v.) antibiotics to resolve; other infections, e.g., bronchitis, sinusitis, localized cellulitis, candidiasis, or urinary tract infections, must

2013 Clinical Trials

163. Renal Cell Carcinoma

; renal cell , renal cell; adenocarcinoma , renal cell; carcinoma , Renal Cell Carcinoma , Renal Cell Adenocarcinoma , Adenocarcinoma of Kidney , Adenocarcinoma of the Kidney , Kidney Adenocarcinoma , Renal Cell Carcinoma, Stage Unspecified , renal carcinoma Swedish Njurcellskarcinom Finnish Munuaissolukarsinooma Italian Adenocarcinoma a cellule renali , Carcinoma renale , Cancro a cellule renali , Carcinoma a cellule renali NAS , Adenocarcinoma del rene , Carcinoma a cellule renali, stadio non (...) specificato , Tumore di Grawitz , Carcinoma a cellule renali Russian GIPERNEFROMA , KARTSINOMA POCHECHNO-KLETOCHNAIA , GRAVITTSA OPUKHOL' , KARTSINOMA GIPERNEFROIDNAIA , ADENOKARTSINOMA POCHECHNO-KLETOCHNAIA , АДЕНОКАРЦИНОМА ПОЧЕЧНО-КЛЕТОЧНАЯ , ГИПЕРНЕФРОМА , ГРАВИТЦА ОПУХОЛЬ , КАРЦИНОМА ГИПЕРНЕФРОИДНАЯ , КАРЦИНОМА ПОЧЕЧНО-КЛЕТОЧНАЯ Spanish Adenocarcinoma de riñón , Adenocarcinoma de células renales , Cáncer de células renales , Carcinoma de células renales, estadio no especificado , Carcinoma de células

2015 FP Notebook

164. Hand-Schuller-Christian Syndrome

gland (which makes hormones that control other glands and many body functions, especially growth). Langerhans cell histiocytosis is most common in children and young adults. Definition (NCI) A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination. Three major overlapping syndromes are recognized: eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is generally related to the number of organs (...) affected at presentation. (WHO, 2001) Definition (NCI) A multifocal, unisystem form of Langerhans-cell histiocytosis. There is involvement of multiple sites in one organ system, most frequently the bone. Patients are usually young children presenting with multiple destructive bone lesions. Definition (CSP) group of disorders of histiocyte proliferation which includes Letterer-Siwe disease; Hand-Schueller-Christian syndrome; and eosinophilic granuloma; Langerhans cells are components of the lesions

2015 FP Notebook

165. Hashimoto's Thyroiditis

tyreoiditt , Hashimotos syndrom , Hashimotos sykdom Derived from the NIH UMLS ( ) Ontology: Hurthle Cells (C0949667) Definition (NCI) A large, granular eosinophilic cell derived from thyroid follicular epithelium by accumulation of mitochondria Definition (MSH) Oxyphil cells in the thyroid gland are known as Hurthle cells and Askenazy cells. Concepts Cell ( T025 ) MSH English Hurthle Cell , Oxyphil cell of thyroid , Thyroid gland oxyphil cell , hurthle cells , hurthle cell , cells hurthles , Askenazy (...) Cells , Cells, Askenazy , Cells, Hurthle , Thyroid Gland Oxyphil Cell , Thyroid Gland Oxyphilic Cell , Hurthle Cells French Cellule de Hürthle , Cellules de Hürthle Czech Hürthleovy buňky , Askenazyho buňky Portuguese Células de Hürthle German Hürthle-Zellen Spanish Células de Hürthle Italian Cellule di Hurthle Norwegian Ashkenazy-celler , Hürthle-celler Dutch Hurthle-cellen Derived from the NIH UMLS ( ) Related Topics in Thyroid Disease About FPnotebook.com is a rapid access, point-of-care medical

2015 FP Notebook

166. Chronic Leukemia

differentiated, usually B-lymphocytes, but immunologically incompetent; types distinguished include chronic granulocytic, chronic lymphocytic, chronic myelomonocytic, eosinophilic and hairy cell leukemia. Concepts Neoplastic Process ( T191 ) ICD9 208.1 ICD10 , , SnomedCT 92812005 , 2557004 , 128933000 , 190027002 , 188764001 , 154600002 English Leukemia of unspecified cell type, chronic , Chronic leukaemia NOS , Chronic leukemia NOS , Chronic leukaemia of unspecified cell type , Chronic leukemia (...) Leucémie chronique SAI , Leucémie à cellules de type non précisé, chronique , Leucémie chronique de type cellulaire non précisé , Leucémie chronique à cellules de type non précisé , Leucémie chronique German Leukaemie, chronisch , chronische Leukaemie eines unspezifischen Zelltyps , chronische Leukaemie NNB , Leukaemie eines unspezifischen Zelltyps, chronisch , Chronische Leukaemie nicht naeher bezeichneten Zelltyps , chronische Leukaemie Portuguese Leucemia crónica NE , Leucemia crónica de tipo

2015 FP Notebook

167. Limited surgical treatment of suspected necrotizing fasciitis of the upper extremity with a benign clinical presentation Full Text available with Trip Pro

is described. A previously healthy 48-year-old man presented with increased erythema, swelling and blistering of his left upper extremity. Despite a benign systemic clinical presentation, the hand and forearm were suspicious for necrotizing fasciitis, prompting surgical treatment. Surgical exploration found a significant amount of intradermal and subdermal clear fluid. It was decided to limit the amount of debridement. The diagnosis was Wells syndrome, eosinophilic cellulitis. Treated with steroids

2012 The Canadian Journal of Plastic Surgery

168. Persistent hypereosinophilia with Wells syndrome. (Abstract)

Persistent hypereosinophilia with Wells syndrome. Since Wells and Smith first described cases of eosinophilic cellulitis (Wells syndrome; WS) in 1979, it has been noted that some but not all patients with WS present with eosinophilia. In the face of idiopathic persistent eosinophilia patients will also then fall within the hypereosinophilic syndrome (HES), which represents a multifarious spectrum of disorders of varying severity, causes and outcomes. In this article we propose that patients who

2012 Clinical & Experimental Dermatology

169. Sinusitis

between/behind the eyes, the sides of the upper part of the nose (the ), and headaches (J01.2/J32.2) – can cause pain or pressure behind the eyes, but is often in the , over the , or the back of the head. Complications [ ] Stage Description I Preseptal cellulitis II Orbital cellulitis III Subperiosteal abscess IV Orbital abscess V Cavernous sinus septic thrombosis The proximity of the brain to the sinuses makes the most dangerous complication of sinusitis, particularly involving the frontal (...) spread to the orbit may result in periorbital , subperiosteal , orbital cellulitis, and abscess. Orbital cellulitis can complicate acute if anterior and posterior enables the spread of the infection to the lateral or orbital side of the . Sinusitis may extend to the , where it may cause cavernous sinus , retrograde , and epidural, subdural, and brain abscesses. Orbital symptoms frequently precede intracranial spread of the infection . Other complications include sinobronchitis, maxillary

2012 Wikipedia

170. List of cutaneous conditions

, vascular rosacea) ( acne excoriée des jeunes filles , Picker's acne) (acne inversa, pyoderma fistulans significa, Verneuil's disease) (granulomatous rosacea, micropapular tuberculid, rosacea-like tuberculid of Lewandowsky) (acne infantum, acne neonatorum, neonatal cephalic pustulosis) (ophthalmic rosacea, ophthalmorosacea) (chronic upper facial erythematous edema, Morbihan's disease, rosaceous lymphedema) (inflammatory rosacea) (dissecting cellulitis of the scalp, dissecting folliculitis (...) , generalized eczema) (diaper dermatitis, napkin dermatitis) (atopic winter feet, dermatitis plantaris sicca, forefoot dermatitis, moon-boot foot syndrome, sweaty sock dermatitis) (discoid eczema, microbial eczema, nummular eczema, nummular neurodermatitis) (oid-oid disease) (asteatotic eczema, desiccation dermatitis, eczema craquelé , pruritus hiemalis, winter eczema, winter itch) Pustular [ ] See also: Pustular dermatitis is an of the skin that presents with . (Ofuji's disease, sterile eosinophilic

2012 Wikipedia

171. Investigating Re-Dosing With Otelixizumab in Adults With Newly-Diagnosed Type 1 Diabetes Mellitus

Baseline value. Mean Change From Baseline in Value of Estradiol [ Time Frame: Baseline and up to Month 24 ] Clinical chemistry parameters were planned to be analyzed from Baseline to Month 24. Day 1 value was considered to be Baseline value. Change from Baseline was planned to be calculated as any post-Baseline value minus Baseline value. Mean Change From Baseline in Basophils, Eosinophils, Lymphocytes, Monocytes, Platelet Count and White Blood Cell Count [ Time Frame: Baseline and up to Month 24 (...) antigen (HBsAg), positive hepatitis C test result within 3 months of screening Significant systemic infection during the 6 weeks before the first dose of study drug (e.g., infection requiring hospitalisation, major surgery, or IV antibiotics to resolve; other infections, e.g., bronchitis, sinusitis, localised cellulitis, candidiasis, or urinary tract infections, must be assessed on a case-by-case basis by the investigator regarding whether they are serious enough to warrant exclusion). History

2010 Clinical Trials

172. GSK1322322 Versus Linezolid in the Treatment of Acute Bacterial Skin and Skin Structure Infection

on Day 1. Mean Hematology Parameters of Basophils, Eosinophils, Lymphocytes, Monocytes, Total Neutrophils, White Blood Cells (WBC) and Platelet Count at Indicated Time Points [ Time Frame: Up to Follow-up (28 Day Follow-up, Day 40) ] Blood samples were obtained for analysis of basophils, eosinophils, lymphocytes, monocytes, total neutrophils, WBC and platelet count at Day 1, Day 4, Day 8, Day 11, 7 Day Follow-up and 28 Day Follow-up. Baseline value was defined as the assessment done on Day 1. Mean (...) -dose). Data is reported for number of participants with abnormal transition from Baseline 'to high' or 'to low' relative to normal range. Only those parameters for which at least one value of abnormal transition was reported are summarized. Number of Participants With Abnormal Transition From Baseline in Hematology Values Relative to Normal Range [ Time Frame: Day 1 (pre-dose, Baseline) up Follow-up (28 Day Follow-up, Day 40) ] The parameters of clinical chemistry included basophils, eosinophils

2010 Clinical Trials

173. Wells syndrome associated with Churg-Strauss syndrome. (Abstract)

Wells syndrome associated with Churg-Strauss syndrome. Churg–Strauss syndrome (CSS) is a systemic vasculitis occurring in patients with a history of asthma. Wells' syndrome (WS) is a rare inflammatory dermatosis that clinically resembles cellulitis, and is histologically characterized by eosinophilic infiltration and flame figures. We report a case of WS associated with CSS. There have been three previous reports of WS associated with CSS; ours is the fourth. All cases had bullous lesions

2010 Clinical & Experimental Dermatology

174. IDIOPATHIC EOSINOPHILIC MENINGOENCEPHALOMYELITIS FOLLOWING WELL SYNDROME Full Text available with Trip Pro

IDIOPATHIC EOSINOPHILIC MENINGOENCEPHALOMYELITIS FOLLOWING WELL SYNDROME 19996079 2009 12 30 2018 11 13 1526-632X 73 23 2009 Dec 08 Neurology Neurology Idiopathic eosinophilic meningoencephalomyelitis following Well syndrome. 2037-9 10.1212/WNL.0b013e3181c55ee7 Turkeltaub Peter E PE Department of Neurology, University of Pennsylvania Health System, Philadelphia, PA 19104, USA. peter.turkeltaub@uphs.upenn.edu Guzman Miguel A MA Lee Edward B EB Galetta Steven L SL eng Case Reports Journal Article (...) United States Neurology 0401060 0028-3878 AIM IM Cellulitis complications diagnosis Encephalomyelitis diagnosis etiology Eosinophilia complications diagnosis Female Humans Meningoencephalitis diagnosis etiology Middle Aged Syndrome 2009 12 10 6 0 2009 12 10 6 0 2009 12 31 6 0 ppublish 19996079 73/23/2037 10.1212/WNL.0b013e3181c55ee7 PMC2790232 Curr Opin Pulm Med. 2007 Sep;13(5):422-7 17940488 Intern Med. 2003 May;42(5):424-7 12793714 Int J Dermatol. 2003 Jan;42(1):62-7 12581147 Proc Natl Acad Sci U S

2009 Neurology

175. Incontinentia pigmenti

methods Typical skin lesions and genetic testing are sufficient for diagnosis. Leukocytosis and eosinophilia may be noted. Skin histology shows eosinophilic spongisostic bulles (stage I); hyperkeratotic and acanthotic epidermis with dyskeratotic keratinocytes (stage II) and loose dermal melanine deposits (stage III). Differential diagnosis Stage I may be misdiagnosed as bullous impetigo, inherited epidermolysis bullosa, herpes or varicella. Differential diagnosis of stage II includes warts, molluscum (...) -linked dominantly. An affected woman has a 50% risk of having affected children. Live-born affected males should be checked for a 47,XXY karyotype. Management and treatment Treatment is symptomatic, including standard management of blisters (not opening them and avoidance of trauma), topical treatment (medication, oatmeal baths) and addressing infections (as in cellulitis). Dental abnormalities should be managed by a pedodontist in combination with speech therapy and a pediatric nutritional program

2005 Orphanet

176. Anti-Interleukin-5 (IL-5) Study for Hypereosinophilic Syndrome

, cardiac, and hepatic function Not pregnant or breastfeeding A diagnosis of hypereosinophilic syndrome such as: Idiopathic hypereosinophilic syndrome; Eosinophilia myalgia syndrome; Eosinophilic gastroenteritis; Churg-Strauss syndrome; Eosinophilic cellulitis; Benign hypereosinophilia; or Eosinophilic esophagitis. Maintained on, or in need of, the following: glucocorticoids, interferon, methotrexate, hydroxyurea, cytoxan, 6-mercaptopurine, or vincristine Blood eosinophil counts greater than 750 cells (...) Medical Center, Cincinnati Study Details Study Description Go to Brief Summary: Toxicity of anti-IL-5 Condition or disease Intervention/treatment Phase Hypereosinophilic Syndromes Eosinophilic Gastroenteritis Churg-Strauss Syndrome Eosinophilic Esophagitis Drug: Mepolizumab Phase 1 Phase 2 Detailed Description: The purpose of the study is to assess the toxicity of anti-IL-5, and to see whether it lowers peripheral blood eosinophils and/or tissue and whether it has a steroid and/or interferon sparing

2005 Clinical Trials

177. Hypereosinophilic syndrome with various skin lesions and juvenile temporal arteritis. (Abstract)

Hypereosinophilic syndrome with various skin lesions and juvenile temporal arteritis. Hypereosinophilic syndrome (HES) is a multisystem disease with a high mortality rate. It is characterized by peripheral blood eosinophilia and eosinophilic infiltration of the skin and many other organs. The commonest cutaneous features include erythematous pruritic maculopapules and nodules, angio-oedema or urticarial plaques. However, some case reports have indicated that eosinophilic cellulitis, cutaneous (...) with eosinophilic cellulitis, Raynaud's phenomenon, digital gangrene and JTA. JTA may also be one of the features of HES.

2008 Clinical & Experimental Dermatology

178. Dermatitis cruris pustulosa et atrophicans--a frequent but poorly understood tropical skin condition--a case report from Burkina Faso. (Abstract)

. A bacterial origin has not been demonstrated in this case. Histology showed an intraepidermal neutrophilic pustule with dermal and subcutaneous infiltration by neutrophils and eosinophils forming flame figures. Different pathogenic hypotheses are discussed with special regard to a potential relationship between DCPA and eosinophilic cellulitis.

2008 International Journal of Dermatology

179. Unexplained hypereosinophilia and the need for cytogenetic and molecular genetic analyses. Full Text available with Trip Pro

patient also had recurrent lesions of eosinophilic cellulitis. All 3 patients were initially diagnosed as having idiopathic HES, but after evaluation and demonstration of molecular abnormalities, they were classified as having eosinophilic leukemia.Patients with a diagnosis of idiopathic HES should be evaluated for cytogenetic or molecular genetic abnormalities. These abnormalities can establish a diagnosis of chronic eosinophilic leukemia and may provide clues for emerging therapies. (...) Unexplained hypereosinophilia and the need for cytogenetic and molecular genetic analyses. Idiopathic hypereosinophilic syndrome (HES) is a diagnosis made after the exclusion of other causes of eosinophilia. However, differentiation of idiopathic HES from eosinophilic leukemia is sometimes difficult. In some cases, these diagnoses can be differentiated by cytogenetic or molecular findings, as illustrated in the patients described herein.We describe 3 patients with HES and associated pruritus; 1

2004 Archives of Dermatology

180. Exaggerated insect bite reaction exacerbated by a pyogenic infection in a patient with chronic lymphocytic leukaemia. (Abstract)

rapidly with ibuprofen, leaving cellulitis around a small ulcer infected with Staphylococcus aureus and Streptococcus pyogenes. The cellulitis responded to oral flucloxacillin. Subsequent multiple small exaggerated insect bite reaction lesions settled with oral prednisolone. Eosinophilic cellulitis (Wells' syndrome) was considered unlikely based on the lack of a morphoea-like resolution phase, histological lack of flame figures and presence of vasculitis; however, the distinction is probably (...) Exaggerated insect bite reaction exacerbated by a pyogenic infection in a patient with chronic lymphocytic leukaemia. A 69-year-old woman with chronic lymphocytic leukaemia presented with an 18-month history of pruritic, tender, erythematous plaques. The recurrent lesions simulated insect bites and cellulitis, but failed to respond to appropriate treatments. A recent severe flare was associated with markedly elevated inflammatory markers and swelling of the left leg. The swelling settled

2007 Australasian Journal of Dermatology

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