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Endometriosis

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1. Endometriosis: diagnosis and management

Endometriosis: diagnosis and management Endometriosis: diagnosis and Endometriosis: diagnosis and management management NICE guideline Published: 6 September 2017 nice.org.uk/guidance/ng73 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When (...) with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Endometriosis: diagnosis and management (NG73) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 24Contents Contents Overview 4 Who is it for? 4 Recommendations 5 1.1

2017 National Institute for Health and Clinical Excellence - Clinical Guidelines

2. Elagolix (Orilissa) - for the treatment of moderate to severe pain associated with endometriosis

Elagolix (Orilissa) - for the treatment of moderate to severe pain associated with endometriosis Search Page - Drug and Health Product Register Language selection Search and menus Search Search website Search Topics menu You are here: Summary Basis of Decision - - Health Canada Expand all Summary Basis of Decision (SBD) for Contact: Summary Basis of Decision (SBD) documents provide information related to the original authorization of a product. The for is located below. Recent Activity for SBDs

2019 Health Canada - Drug and Health Product Register

4. Endometriosis

Endometriosis Endometriosis - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Endometriosis Last reviewed: February 2019 Last updated: March 2019 Summary Chronic inflammatory condition defined by endometrial stroma and glands found outside of the uterine cavity. The most common sites affected are the pelvic peritoneum and ovaries. May present incidentally in asymptomatic patients, or more commonly in women (...) of lesions. Controlled ovarian hyper-stimulation and IVF may be considered for patients with sub-fertility. Individualised care for patients with pelvic pain should incorporate a multi-disciplinary evaluation and treatment plan that focuses on limiting the risk of recurrence and improving quality of life. Definition Endometriosis is defined as the presence of endometrial glands and stroma outside the endometrial cavity and uterine musculature. Surgical appearance varies significantly from superficial

2018 BMJ Best Practice

5. Oral contraceptives for pain associated with endometriosis. (PubMed)

Oral contraceptives for pain associated with endometriosis. Endometriosis is a common gynaecological condition which affects many women of reproductive age worldwide and is a major cause of pain and infertility. The combined oral contraceptive pill (COCP) is widely used to treat pain occurring as a result of endometriosis, although the evidence for its efficacy is limited.To determine the effectiveness, safety and cost-effectiveness of oral contraceptive preparations in the treatment of painful (...) handsearched reference lists of relevant trials and systematic reviews retrieved by the search.We included randomised controlled trials (RCT) of the use of COCPs in the treatment of women of reproductive age with symptoms ascribed to the diagnosis of endometriosis that had been made visually at a surgical procedure.Two review authors independently assessed study quality and extracted data. One review author was an expert in the content matter. We contacted study authors for additional information

2018 Cochrane

6. Recommendations for surgical treatment of endometriosis. Part 1: Ovarian Endometrioma

Recommendations for surgical treatment of endometriosis. Part 1: Ovarian Endometrioma We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Recommendations for the Surgical Treatment of Endometriosis. Part 1: Ovarian Endometrioma†‡¶ | Human Reproduction Open | Oxford Academic Search Account Menu Menu Navbar Search Filter Mobile Microsite Search Term Close search filter (...) search input Article Navigation Close mobile search navigation Article navigation 2017 Article Contents Article Navigation Recommendations for the Surgical Treatment of Endometriosis. Part 1: Ovarian Endometrioma Ertan Saridogan Institute for Women's Health, University College Hospital, Reproductive Medicine Unit, Elizabeth Garrett Anderson Wing, London NW1 2BU, UK Correspondence address. Institute for Women's Health, University College Hospital, Reproductive Medicine Unit, Elizabeth Garrett Anderson

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2018 European Society of Human Reproduction and Embryology

7. Endometriosis

Endometriosis Top results for endometriosis - Trip Database or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2 (...) ) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for endometriosis The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms

2018 Trip Latest and Greatest

8. Dysmenorrhea and Endometriosis in the Adolescent

Dysmenorrhea and Endometriosis in the Adolescent Dysmenorrhea and Endometriosis in the Adolescent - ACOG Menu ▼ Dysmenorrhea and Endometriosis in the Adolescent Page Navigation ▼ Number 760 Committee on Adolescent Health Care This Committee Opinion was developed by the American College of Obstetricians and Gynecologists’ Committee on Adolescent Health Care in collaboration with committee members Geri D. Hewitt, MD and Karen R. Gerancher, MD. This information is designed as an educational (...) accepted any commercial involvement in the development of the content of this published product. Dysmenorrhea and Endometriosis in the Adolescent ABSTRACT: Dysmenorrhea, or menstrual pain, is the most common menstrual symptom among adolescent girls and young women. Most adolescents experiencing dysmenorrhea have primary dysmenorrhea , defined as painful menstruation in the absence of pelvic pathology. When the patient’s history suggests primary dysmenorrhea, empiric treatment should be initiated. When

2019 American College of Obstetricians and Gynecologists

9. Endometriosis factsheet

Endometriosis factsheet Endometriosis factsheet Endorsed by2 What is endometriosis? Do you see female patients? Do they have painful periods? Pain pre or post their periods? Painful sex? Do they suffer chronic pain, which may be intermittent or constant? Do they have pain when passing urine or with bowel movements? Is it painful to place a speculum for a smear test? Have you considered endometriosis? One in 10 women have endometriosis and it takes an average of seven years for most women to get (...) diagnosed. Endometriosis can often be confused with or misdiagnosed as IBS (irritable bowel syndrome). It is important that women receive a early diagnosis, or working diagnosis, of endometriosis even if hormonal treatments appear to be working, as women need to understand that they have a long term, chronic condition and the impact this might have on their future and their fertility. What is endometriosis? Endometriosis is defined as the presence of endometrial-like tissue outside the uterus, which

2018 Royal College of Nursing

10. Progesterone receptor modulators for endometriosis. (PubMed)

Progesterone receptor modulators for endometriosis. Endometriosis is defined as the presence of endometrial tissue (glands and stroma) outside the uterine cavity. This condition is oestrogen-dependent and thus is seen primarily during the reproductive years. Owing to their antiproliferative effects in the endometrium, progesterone receptor modulators (PRMs) have been advocated for treatment of endometriosis.To assess the effectiveness and safety of PRMs primarily in terms of pain relief (...) or bleeding (OR 22.92, 95% CI 2.64 to 198.66; one RCT, n = 49; low-quality evidence).Evidence was insufficient to show differences in effectiveness or safety between different doses of gestrinone, if present. Asoprisnil versus placebo One study (n = 130) made this comparison but did not report data suitable for analysis. Ulipristal versus leuprolide acetate One study (n = 38) made this comparison but did not report data suitable for analysis.Among women with endometriosis, moderate-quality evidence shows

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2017 Cochrane

11. Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis. (PubMed)

Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis. Endometriosis is a common gynaecological condition that affects women and can lead to painful symptoms and infertility. It greatly affects women's quality of life, impacting their careers, everyday activities, sexual and nonsexual relationships and fertility. Nonsteroidal anti-inflammatory drugs (NSAIDs) are most commonly used as first-line treatment for women with pain associated with endometriosis.To assess effects (...) of NSAIDs used for management of pain in women with endometriosis compared with placebo, other NSAIDs, other pain management drugs or no treatment.We searched the Cochrane Gynaecology and Fertility Group Specialised Register of Controlled Trials (October 2016), published in the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, as well as MEDLINE (January 2008 to October 2016), Embase (date limited from 1 January 2016 to 19 October 2016, as all earlier references

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2017 Cochrane

12. [Effect of GnRHa therapy following conservative laparoscopic surgery for endometriosis on clinical pregnant rate in patients with endometriosis-associated infertility]. (PubMed)

[Effect of GnRHa therapy following conservative laparoscopic surgery for endometriosis on clinical pregnant rate in patients with endometriosis-associated infertility]. To investigate the impact of conservative laparoscopic surgery for endometriosis with postoperative gonadotropin-releasing hormone agonist (GnRHa) therapy on the pregnancy outcomes in patients with endometriosis-associated infertility.The clinical data were collected from the patients with endometriosis-associated infertility (...) undergoing conservative laparoscopic surgery in our department between January, 2011 and December, 2016. The patients were divided into laparoscopic surgery only group (without any other treatments) and postoperative GnRha therapy group, and the pregnancy outcomes were compared between the two groups at different time points during the follow-up.In cases with moderate or severe endometriosis, laparoscopic surgery with postoperative GnRha therapy was associated with a significantly higher clinical

2019 Nan fang yi ke da xue xue bao = Journal of Southern Medical University

13. The Endometriosis Impact Questionnaire (EIQ): a tool to measure the long-term impact of endometriosis on different aspects of women's lives. (PubMed)

The Endometriosis Impact Questionnaire (EIQ): a tool to measure the long-term impact of endometriosis on different aspects of women's lives. Endometriosis is a chronic disease impacting on many aspects of a woman's life. Because of the chronic and recurring nature, many of the impacts of endometriosis could be missed using existing questionnaires which focus on recent events. Therefore, a questionnaire with a long-term perspective is necessary. This study aimed to develop and evaluate (...) a questionnaire to measure the long-term impact of endometriosis on different aspects of women's lives.Through a methodological design, phase 1 was qualitative and phase 2 was a cross-sectional study. The original 100 EIQ items were developed based on results from an earlier qualitative study and literature review. Through a process of assessing face and content validity this was reduced to 66 items. The psychometric properties of the final 63 item EIQ were evaluated through a web-based survey with data from

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2019 BMC Women's Health

14. Fertility performance and the predictive value of the endometriosis fertility index staging system in women with recurrent endometriosis: A retrospective study. (PubMed)

Fertility performance and the predictive value of the endometriosis fertility index staging system in women with recurrent endometriosis: A retrospective study. This study presents the postoperative pregnancy rate of women with recurrent endometriosis and evaluates the predictive value of the endometriosis fertility index (EFI) for the pregnancy.A total of 107 women who wished to conceive after surgery for recurrent endometriosis from January 2007 to December 2016 were included. The EFI score (...) % and 66.38%, respectively, and increased to 71.98% within the first 5 years postoperatively in patients with EFI scores ≥5. However, the CPR was 26.00% during the first 2 years after surgery in individuals with EFI scores <5, and there was no increase in the CRP thereafter.Women suffering from recurrent endometriosis still experienced a probability of natural pregnancy, especially patients with EFI scores ≥5. The EFI score had good predictive power for postoperative pregnancy in these patients.

2019 Medicine

15. Deep endometriosis transvaginal ultrasound in the workup of patients with signs and symptoms of endometriosis: a cost analysis. (PubMed)

Deep endometriosis transvaginal ultrasound in the workup of patients with signs and symptoms of endometriosis: a cost analysis. Deep endometriosis transvaginal ultrasound (DE TVS) is accurate in the detection of ovarian endometriosis and DE; however, realisation of its full potential and utilisation remains variable. As such, patients may require a two-step surgical approach (diagnostic followed by therapeutic laparoscopy) or experience incomplete surgical treatment. Besides the clinical (...) implications, the economic impact of a two-step approach to diagnosis and treatment on the healthcare system is likely to be significant. We aim to compare the economic costs of two diagnostic models of care for patients with potential endometriosis.Cost analysis using Markov model with 12-month time horizon comparing the economic costs of two diagnostic models.The study used a hypothetical population of 1000 women visiting a public tertiary gynaecology clinic.Women with potential endometriosis. Estimates

2019 BJOG

16. Elagolix for Treating Endometriosis

Elagolix for Treating Endometriosis ©Institute for Clinical and Economic Review, 2018 Elagolix for Treating Endometriosis Evidence Report June 15, 2018 Prepared for ©Institute for Clinical and Economic Review, 2018 Page i Evidence Report– Elagolix for Treating Endometriosis ICER Staff/Consultants University of Colorado Skaggs School of Pharmacy Modeling Group* Steven J. Atlas, MD, MPH Director, Primary Care Research and Quality Improvement Network Massachusetts General Hospital Geri Cramer, BSN (...) , 2018 Page ii Evidence Report– Elagolix for Treating Endometriosis About ICER The Institute for Clinical and Economic Review (ICER) is an independent non-profit research organization that evaluates medical evidence and convenes public deliberative bodies to help stakeholders interpret and apply evidence to improve patient outcomes and control costs. Through all its work, ICER seeks to help create a future in which collaborative efforts to move evidence into action provide the foundation for a more

2018 California Technology Assessment Forum

17. Elagolix for Treating Endometriosis

Elagolix for Treating Endometriosis ©Institute for Clinical and Economic Review, 2018 Elagolix for Treating Endometriosis Final Evidence Report August 03, 2018 Prepared for ©Institute for Clinical and Economic Review, 2018 Page i Final Evidence Report– Elagolix for Treating Endometriosis ICER Staff/Consultants University of Colorado Skaggs School of Pharmacy Modeling Group* Steven J. Atlas, MD, MPH Director, Primary Care Research and Quality Improvement Network Massachusetts General Hospital (...) and Economic Review, 2018 Page ii Final Evidence Report– Elagolix for Treating Endometriosis About ICER The Institute for Clinical and Economic Review (ICER) is an independent non-profit research organization that evaluates medical evidence and convenes public deliberative bodies to help stakeholders interpret and apply evidence to improve patient outcomes and control costs. Through all its work, ICER seeks to help create a future in which collaborative efforts to move evidence into action provide

2018 California Technology Assessment Forum

18. Management of endometriosis

Management of endometriosis Haute Autorité de Santé - Management of endometriosis Fermer Choose language Accessibility Change contrast : Standards Reinforced icone Chercher icone plus Chercher My account My account Please fill in your email address to retrieve your email alerts subscriptions. Please fill in your email address to retrieve your newsletter subscriptions. You do not have a saved search Sélection No element in selection Services Services Déclarer un événement indésirable grave (...) Comment déclarer les EIGS Etre accrédité par la HAS Médecins exerçant une spécialité «à risques» Déposer une demande d'évaluation d'actes Modalités et procédures Organiser les soins, les parcours Coordination des soins, coopération entre professionnels Rechercher une recommandation, un guide, un médicament Rechercher une recommandation, un médicament, un guide Date : 13 December 2017 Mise à jour : 06/12/2018 Management of endometriosis Practice guidelines - Posted on Jan 17 2018 This clinical practice

2018 HAS Guidelines

19. Combination of the non-invasive tests for the diagnosis of endometriosis. (PubMed)

Combination of the non-invasive tests for the diagnosis of endometriosis. About 10% of women of reproductive age suffer from endometriosis, a costly chronic disease causing pelvic pain and subfertility. Laparoscopy is the gold standard diagnostic test for endometriosis, but is expensive and carries surgical risks. Currently, there are no non-invasive tests available in clinical practice to accurately diagnose endometriosis. This review assessed the diagnostic accuracy of combinations (...) of different non-invasive testing modalities for endometriosis and provided a summary of all the reviews in the non-invasive tests for endometriosis series.To estimate the diagnostic accuracy of any combination of non-invasive tests for the diagnosis of pelvic endometriosis (peritoneal and/or ovarian or deep infiltrating) compared to surgical diagnosis as a reference standard. The combined tests were evaluated as replacement tests for diagnostic surgery and triage tests to assist decision-making

2016 Cochrane

20. Endometrial biomarkers for the non-invasive diagnosis of endometriosis. (PubMed)

Endometrial biomarkers for the non-invasive diagnosis of endometriosis. About 10% of reproductive-aged women suffer from endometriosis, which is a costly, chronic disease that causes pelvic pain and subfertility. Laparoscopy is the gold standard diagnostic test for endometriosis, but it is expensive and carries surgical risks. Currently, there are no non-invasive tests available in clinical practice that accurately diagnose endometriosis. This is the first diagnostic test accuracy review (...) of endometrial biomarkers for endometriosis that utilises Cochrane methodologies, providing an update on the rapidly expanding literature in this field.To determine the diagnostic accuracy of the endometrial biomarkers for pelvic endometriosis, using a surgical diagnosis as the reference standard. We evaluated the tests as replacement tests for diagnostic surgery and as triage tests to inform decisions to undertake surgery for endometriosis.We did not restrict the searches to particular study designs

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2016 Cochrane

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