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41. Management of Diabetes Mellitus in Primary Care

which Work Group members were recruited. The specialties and clinical areas of interest included endocrinology, internal medicine, nutrition, pharmacy, health education, nursing, medical management, ambulatory care, and family practice. The guideline development process for the 2017 CPG update consisted of the following steps: 1. Formulating and prioritizing KQs 2. Conducting a patient focus group 3. Conducting the SRVA/DoD Clinical Practice Guideline for the Management of Type 2 Diabetes Mellitus

2017 VA/DoD Clinical Practice Guidelines

42. Pioglitazone (brand name: Actos) and bladder cancer: A new type "time-related bias"

. It is defined in the book Modern Epidemiology (K. Rothman, S. Greenland, T. Lash. 3rd Edition, Lippincott Williams & Wilkins, 2008 p. 106-7) [26]. The exposure definition in the methods of Kaiser study: “Ever use” of pioglitazone and other diabetes medications was defined as “having filled 2 prescriptions for the drug within a 6-month period”. Once a patient met the exposure definition, he or she was considered exposed from that point forward. Figure 3 shows 12 typical individuals by the exposure state (...) , 16)Hama R and Kimoto Y. Pioglitazone and related agents (including Actos) should be banned TIP “The Informed Prescriber”2011:26 (6): 86-91. 17) Mascitelli L, Pezzetta F. Thiazolidinediones. N Engl J Med 2005; 352: 206. 18) Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002;418: 41-9. 19) Rzonca SO, Suva LJ, Gaddy D, Montague DC, Lecka-Czernick B. Bone is a target for the antidiabetic compound rosiglitazone. Endocrinology

2016 Med Check - The Informed Prescriber

43. Diagnosis and management of Silver-Russell syndrome: 1st international consensus statement

publications (89 in PubMed), review articles and book contributions. , Justin Davies is a Consultant in Paediatric Endocrinology and Diabetes, University Hospital Southampton, and senior lecturer in child health, University of Southampton, UK. His research interest is in childhood bone disorders and diseases affecting body composition in children. He is service lead for paediatric endocrinology and has initiated a national multidisciplinary specialist service for Silver–Russell syndrome. He has over 50 (...) Diagnosis and management of Silver-Russell syndrome: 1st international consensus statement Diagnosis and management of Silver–Russell syndrome: first international consensus statement | Nature Reviews Endocrinology Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we

2017 Pediatric Endocrine Society

45. Clinical Practice Guidelines on Hypertension

or ABPM (in that order) should be offered to younger patients, and to those whom target organ damage is found without a raised clinic BP. Grade D, Level 4 20 4 The preferred manometer is an automated oscillometric device, with or without memory. Grade C, Level 2 + 21 5 To ensure reliable values, the patient or carer needs training in device use, and a BP log-book (for basic devices without memory). Grade D, Level 4 21 6 ABPM is recommended whenever in doubt about the diagnosis, e.g. to confirm

2017 Ministry of Health, Singapore

46. Safe midwifery staffing for maternity settings

for safe midwifery staffing 50 Safe midwifery staffing for maternity settings (NG4) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 4 of 67Safe midwifery staffing for maternity settings indicator: outcome measures reported by women in maternity services 50 Safe midwifery staffing for maternity settings indicator: booking appointment within 13 weeks of pregnancy (or sooner) 53 Safe midwifery staffing for maternity (...) of maternity care hours by the number of women in the time period to determine the historical average maternity care hours needed per woman. Use data on the number of women who are currently accessing the maternity service and the trend in new bookings to predict the number of women in the service in the next 6 months. Multiply the predicted number of women in the service over the next 6 months by the Safe midwifery staffing for maternity settings (NG4) © NICE 2019. All rights reserved. Subject to Notice

2015 National Institute for Health and Clinical Excellence - Clinical Guidelines

50. Clinical Practice Guidelines on Obesity

per day, best to spread this activity throughout the week). Qualified supervision may be offered to assist with assessment and individual exercise prescription. (pg 97) Grade B, Level 2 + Complications of obesity in pregnancy: B Consider booking an early visit to plan pregnancy care. A pregnancy care plan with increased clinical surveillance is recommended for obese, pregnant women in the antenatal, intrapartum and postnatal periods. Consider a cardiac risk assessment for women with pre-existing (...) , and exercise and behavioural therapists. 1.3 Guideline development The Obesity CPG is developed by a committee appointed by the Health Promotion Board, a statutory board under the Ministry of Health. The committee comprises of specialists from the fields of endocrinology, surgery, paediatrics, family medicine, obstetrics and gynaecology, sports science and physical activity, nutrition and dietetics, behavioural sciences and psychology as well as public health specialists. The guidelines are developed

2016 Ministry of Health, Singapore

52. FreeStyle Libre for glucose monitoring

. If adopted, additional costs would be incurred for the purchase of readers and sensors, but the number of blood glucose testing strips needed may be reduced. Additional clinician time may be needed to read and analyse the ambulatory glucose profile reports, although this may be equivalent to the time taken to read and analyse information from the patient's glucose log book. Costs may be saved if using FreeStyle Libre leads to better monitoring and control of glucose levels, and a subsequent reduction (...) declared. Mrs Debbie Hicks, nurse consultant in diabetes, Enfield Health, Barnet, Enfield and Haringey Mental Health Trust. Mrs Hicks has received honoraria from Abbott for giving presentations at educational events plus attendance on advisory boards. Dr Karen Anthony, consultant in diabetes and endocrinology, The Whittington Hospital NHS Trust: No conflicts of interest declared. Additional reviewer: Mrs Victoria Gibson, formulary support/contracts and commissioning senior pharmacist, Medicines

2017 National Institute for Health and Clinical Excellence - Advice

53. Recombinant growth hormone therapy for cystic fibrosis in children and young adults. (PubMed)

of recombinant human growth hormone therapy in improving lung function, quality of life and clinical status of children and young adults with cystic fibrosis.We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group's Trials Register comprising references identified from comprehensive electronic database searches and handsearches of relevant journals and abstract books of conference proceedings. Date of latest search: 11 February 2015.We conducted a search of relevant endocrine journals (...) and proceedings of the Endocrinology Society meetings using Scopus and Proceedings First. Date of latest search: 04 March 2015.Randomised and quasi-randomised controlled trials of all preparations of recombinant growth hormone compared to either no treatment, or placebo, or each other at any dose (high-dose and low-dose) or route and for any duration, in children or young adults aged up to 25 years diagnosed with cystic fibrosis (by sweat test or genetic testing).Two authors independently screened papers

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2015 Cochrane

56. Hypothyroidism

to conception, at booking when pregnant, and at 6–8 weeks postpartum (or after miscarriage or termination of pregnancy). Is known to be thyroid autoantibody positive — screen at the earliest opportunity, during pregnancy and at 6–8 weeks, and 6 months postpartum (or after miscarriage or termination of pregnancy). Has a history of radiotherapy to the head or neck — screen at the earliest opportunity. Has had a previous miscarriage or preterm delivery — screen at the earliest opportunity. Is morbidly obese (...) to endocrinology The recommendations on who to refer to endocrinology are based on the US clinical guideline Clinical practice guidelines for hypothyroidism in adults [ ] and expert opinion in a review article [ ]. Levothyroxine (LT4) is the standard treatment for hypothyroidism The recommendation on the use of levothyroxine monotherapy as the standard treatment for hypothyroidism is based on the clinical guidelines Clinical practice guidelines for hypothyroidism in adults [ ], The use of L-T4 + L-T3

2018 NICE Clinical Knowledge Summaries

57. Jeffrey Aronson: When I use a word . . . Non-steroidal anti-inflammatory drugs—origin of the term

of Endocrinology in Copenhagen in 1960, in which they wrote “We have studied the effects of a number of glucocorticoids and also of some non-steroid anti-inflammatory agents upon the biogenesis of cartilage in tissue culture.” Buer suggested that that was the first use of the term. Whitehouse and Last used the term again in a in Nature in 1961, after which it started to become more widely used, although uptake did not really become widespread until the mid-1970s (Figure 1). Figure 1. The numbers of papers (...) -inflammatory agent” (Figure 3). Similar adverts appeared on 10 October 1957 and 11 January 1958. There may be earlier examples still, but I haven’t found any. A search in Google Books suggests that there may also be an instance in a of the Journal of the South African Veterinary Medical Association , but I have not been able to locate a copy of that. Figure 3. An advertisement for “a new non-steroidal anti-inflammatory agent” in The BMJ on 21 September 1957; this instance antedates the earliest citation

2018 The BMJ Blog

58. Oncogenetic testing for persons with hereditary endocrine cancer syndromes

the presence of a mutation. Furthermore, the general philosophy of the GRADE system for interventions (see KCE process book, http://processbook.kce.fgov.be/node/51) was also used for this report (more specifically for the grading of the recommendations). The report was validated by three external assessors, listed in the colophon. Subsequently, the recommendations were circulated to the GDG and the stakeholders (associations of physicians and patient organisations) targeted by this guideline. Each (...) (NOVARTIS-SANDOZ); Advisory Board IPSEN-NOVARTIS), Bruno Lapauw (several post-graduate courses including for GP’s; support participation several congresses in the domain of endocrinology), Kris Poppe (Merck symposium 2011) Presidency or accountable function within an institution, association, department or other entity on which the results of this report could have an impact: Bruce Poppe (Universiteit Gent; UZ Gent) Participation in scientific or experimental research as an initiator, principal

2015 Belgian Health Care Knowledge Centre

59. Recombinant growth hormone therapy for cystic fibrosis in children and young adults. (PubMed)

of recombinant human growth hormone therapy in improving lung function, quality of life and clinical status of children and young adults with cystic fibrosis.We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group's Trials Register comprising references identified from comprehensive electronic database searches and handsearches of relevant journals and abstract books of conference proceedings. Date of latest search: 15 May 2013.We conducted a search of relevant endocrine journals and proceedings (...) of the Endocrinology Society meetings using Scopus and Proceedings First. Date of latest search: 15 March 2012.Randomised and quasi-randomised controlled trials of all preparations of recombinant growth hormone compared to either no treatment, or placebo, or each other at any dose (high-dose and low-dose) or route and for any duration, in children or young adults aged up to 25 years diagnosed with cystic fibrosis (by sweat test or genetic testing).Two authors independently screened papers, extracted trial details

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2013 Cochrane

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