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Endocrine Manifestations of HIV

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1. Endocrine Manifestations of HIV

Endocrine Manifestations of HIV Endocrine Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Endocrine (...) Manifestations of HIV Endocrine Manifestations of HIV Aka: Endocrine Manifestations of HIV , HIV related endocrine complications II. Manifestations or Most common endocrine disease in HIV patients Characterized by low (and dyslipidemia) See Obtain lipid profile and at HIV diagnosis and then at intervals after More common with highly active s Also associated with low s III. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term

2018 FP Notebook

2. Head and neck manifestations of HIV

Head and neck manifestations of HIV Head and neck manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Head and neck (...) manifestations of HIV Head and neck manifestations of HIV Aka: Head and neck manifestations of HIV , HIV related head and neck complications II. Associated Conditions ( ) May progress to esophageal s May occur with normal s May occur in early HIV with normal s Consider Differential Diagnosis Oral and Primary HSV gingivostomatitis Most common oral Lesions on Similar lesions in B-Cell Same l pathogens as in non-HIV patients Pseudomonas aeruginosa amy be seen in advanced HIV See Viral Presents with gradual, non

2018 FP Notebook

3. Dermatologic Manifestations of HIV

Dermatologic Manifestations of HIV Dermatologic Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Dermatologic (...) Manifestations of HIV Dermatologic Manifestations of HIV Aka: Dermatologic Manifestations of HIV , HIV Related Rash , HIV Related Dermatologic Complications , Pruritus in HIV II. Symptoms: Pruritus May be presentation without associated rash or Other causes of Pruritus in HIV failure with cholestasis III. Signs Early, Acute HIV (prior to Seroconversion) Transient, r, r rash on trunk Late HIV (40 to 80% of HIV patients) (40 to 80% of HIV patients) and infectious ( ) IV. Reference Images: Related links

2018 FP Notebook

4. Cardiovascular Manifestations of HIV

Cardiovascular Manifestations of HIV Cardiovascular Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Cardiovascular Manifestations of HIV Cardiovascular Manifestations of HIV Aka: Cardiovascular Manifestations of HIV , HIV related Cardiovascular Complications , HIV Cardiomyopathy II. Causes: Infection Cryptococcus neoformans (CMV) (EBV) III. Causes: Medication adverse effects Direct cardiotoxicity ( ) ( ) Dyslipidemia or s (especially boosted s) Elvitegravir/cobicistat IV. Findings Common Longstanding HIV carries a coronary disease equivalent risk similar to <500 is associated with an increased risk

2018 FP Notebook

5. Renal Manifestations of HIV

Renal Manifestations of HIV Renal Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Renal Manifestations of HIV (...) Renal Manifestations of HIV Aka: Renal Manifestations of HIV , HIV related renal complications II. Associated Conditions: Renal dysfunction ( ) Fluid and electrolyte abnormalities and common due to occult infection Drug induced Renal toxicity See Amphotericin B Foscarnet s fumarate (TDF) Causes proximal tubule dysfunction (e.g. ) and decreased Avoid if GFR <60 ml/min and discontinue if GFR falls more than 25% or <60 ml/min May safely use as alternative (less nephrotoxic) III. References Images

2018 FP Notebook

6. Neurologic Manifestations of HIV

Neurologic Manifestations of HIV Neurologic Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Neurologic (...) Manifestations of HIV Neurologic Manifestations of HIV Aka: Neurologic Manifestations of HIV , HIV Related Neurologic Complications , HIV Infection with Neurologic Disease II. Epidemiology HIV patients with neurologic complications: 39-70% III. Symptoms: Common presentations s Focal neurological deficits See at time of seroconversion See CSF shows lymphocytic and high protein IV. Associated Conditions: Neurologic Primary Central Nervous System Presents with , blurred vision, s, personality or cognitive

2018 FP Notebook

7. Pulmonary manifestations of HIV

Pulmonary manifestations of HIV Pulmonary manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Pulmonary (...) manifestations of HIV Pulmonary manifestations of HIV Aka: Pulmonary manifestations of HIV , HIV related pulmonary complications II. Epidemiology HIV and abuse both play major roles in the increased risk of and Lung patients III. Causes: General causes lung infection in HIV Typical occurs in HIV patients e occurs in advanced HIV with CD4 < 500 Pneumocystis occurs in advanced HIV with CD4 < 200 IV. Causes: Cavitary Lesions Pneumococcus Cryptococcus neoformans Rhodococcus equi (especially Pseudomonas) V

2018 FP Notebook

8. Gynecologic Manifestations of HIV

Gynecologic Manifestations of HIV Gynecologic Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Gynecologic (...) Manifestations of HIV Gynecologic Manifestations of HIV Aka: Gynecologic Manifestations of HIV , HIV related Gynecologic Complications II. Associated Conditions: Invasive Cervical Cancer (AIDS defining disease) Progressive enhances HPV replication HPV infection is very common in HIV HPV Implicated in and anal carcinoma Monitor high risk patient with every 6 months Women with <200 III. Associated Conditions: Infectious Vaginitis Occurs in 20-30% HIV infected women if >500 Recurrent in young women suggests HIV

2018 FP Notebook

9. Gastrointestinal Manifestations of HIV

Gastrointestinal Manifestations of HIV Gastrointestinal Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Gastrointestinal Manifestations of HIV Gastrointestinal Manifestations of HIV Aka: Gastrointestinal Manifestations of HIV , HIV-related Gastrointestinal Conditions II. Differential Diagnosis Infectious esophagitis, and colitis (or ) (or ) Infiltrative hepatobiliary infections Infiltrative pancreatic infections Rectal lesions s (especially anorectal warts) Anorectal lesions (consider ) Medication adverse effects: therapy , and Common adverse effects (esp. s) Inquire about side effects at each visit to prevent

2018 FP Notebook

10. Endocrine Manifestations of HIV

Endocrine Manifestations of HIV Endocrine Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Endocrine (...) Manifestations of HIV Endocrine Manifestations of HIV Aka: Endocrine Manifestations of HIV , HIV related endocrine complications II. Manifestations or Most common endocrine disease in HIV patients Characterized by low (and dyslipidemia) See Obtain lipid profile and at HIV diagnosis and then at intervals after More common with highly active s Also associated with low s III. References Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term

2015 FP Notebook

11. Evaluation of Endocrine Therapy Effects of Host Immunity in Early Stage Breast Cancer

1 year. ] Blood will be assessed at each time point to understand the impact of endocrine therapy in T cell exhaustion. Changes in myeloid-derived suppressor cells in premenopausal vs postmenopausal women treated with aromatase inhibitors. [ Time Frame: Through study completion, approximately 1 year. ] Blood will be assess at each time point to understand the impact of endocrine therapy on myeloid-derived suppressor cells. Changes in physical manifestations with the Patient-Reported Outcomes (...) Evaluation of Endocrine Therapy Effects of Host Immunity in Early Stage Breast Cancer Evaluation of Endocrine Therapy Effects of Host Immunity in Early Stage Breast Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2018 Clinical Trials

12. Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current Insomnia

Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current Insomnia Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current Insomnia - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save (...) this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current Insomnia The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details

2016 Clinical Trials

13. HIV, viral hepatitis and STIs - a guide for primary care

, there will be a brief discussion about bacterial vaginosis because it is very common. Bacterial vaginosis may not be a true STI as it can occur in celibate women on rare occasions and treating the sexual partners of women with bacterial vaginosis has no effect on recurrence rates in index patients.HIV, VIRAL HEPATITIS AND STIs – A GUIDE FOR PRIMARY HEALTH CARE 11 Biology (virology and microbiology) HIV The manifestations of HIV were first apparent in the early 1980s when an epidemic of unexplained cases (...) HIV, viral hepatitis and STIs - a guide for primary care HIV , VIRAL HEPATITIS & STIs SUPPOR TING THE HIV, VIR AL HEPATITIS AND SEXUAL HEALTH WORKFOR CE A GUIDE FOR PRIMARY CARE PROVIDERS HIV, VIRAL HEPATITIS & STIsHIV, VIRAL HEPATITIS AND STIs – A GUIDE FOR PRIMARY HEALTH CARE i HIV , VIRAL HEPATITIS & STIs SUPPOR TING THE HIV, VIRAL HEPATITIS AND SEXUAL HEALTH W ORKFOR CE A GUIDE FOR PRIMARY CAREii HIV, VIRAL HEPATITIS AND STIs – A GUIDE FOR PRIMARY HEALTH CAREHIV, VIRAL HEPATITIS AND STIs

2014 Clinical Practice Guidelines Portal

14. Gastrointestinal Manifestations of HIV

Gastrointestinal Manifestations of HIV Gastrointestinal Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Gastrointestinal Manifestations of HIV Gastrointestinal Manifestations of HIV Aka: Gastrointestinal Manifestations of HIV , HIV-related Gastrointestinal Conditions II. Differential Diagnosis Infectious esophagitis, and colitis (or ) (or ) Infiltrative hepatobiliary infections Infiltrative pancreatic infections Rectal lesions s (especially anorectal warts) Anorectal lesions (consider ) Medication adverse effects: therapy , and Common adverse effects (esp. s) Inquire about side effects at each visit to prevent

2015 FP Notebook

15. Head and neck manifestations of HIV

Head and neck manifestations of HIV Head and neck manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Head and neck (...) manifestations of HIV Head and neck manifestations of HIV Aka: Head and neck manifestations of HIV , HIV related head and neck complications II. Associated Conditions ( ) May progress to esophageal s May occur with normal s May occur in early HIV with normal s Consider Differential Diagnosis Oral and Primary HSV gingivostomatitis Most common oral Lesions on Similar lesions in B-Cell Same l pathogens as in non-HIV patients Pseudomonas aeruginosa amy be seen in advanced HIV See Viral Presents with gradual, non

2015 FP Notebook

16. Dermatologic Manifestations of HIV

Dermatologic Manifestations of HIV Dermatologic Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Dermatologic (...) Manifestations of HIV Dermatologic Manifestations of HIV Aka: Dermatologic Manifestations of HIV , HIV Related Rash , HIV Related Dermatologic Complications , Pruritus in HIV II. Symptoms: Pruritus May be presentation without associated rash or Other causes of Pruritus in HIV failure with cholestasis III. Signs Early, Acute HIV (prior to Seroconversion) Transient, r, r rash on trunk Late HIV (40 to 80% of HIV patients) (40 to 80% of HIV patients) and infectious ( ) IV. Reference Images: Related links

2015 FP Notebook

17. Cardiovascular Manifestations of HIV

Cardiovascular Manifestations of HIV Cardiovascular Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 (...) Cardiovascular Manifestations of HIV Cardiovascular Manifestations of HIV Aka: Cardiovascular Manifestations of HIV , HIV related Cardiovascular Complications , HIV Cardiomyopathy II. Causes: Infection Cryptococcus neoformans (CMV) (EBV) III. Causes: Medication adverse effects Direct cardiotoxicity ( ) ( ) Dyslipidemia or s (especially boosted s) Elvitegravir/cobicistat IV. Findings Common Longstanding HIV carries a coronary disease equivalent risk similar to <500 is associated with an increased risk

2015 FP Notebook

18. Pulmonary manifestations of HIV

Pulmonary manifestations of HIV Pulmonary manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Pulmonary (...) manifestations of HIV Pulmonary manifestations of HIV Aka: Pulmonary manifestations of HIV , HIV related pulmonary complications II. Epidemiology HIV and abuse both play major roles in the increased risk of and Lung patients III. Causes: General causes lung infection in HIV Typical occurs in HIV patients e occurs in advanced HIV with CD4 < 500 Pneumocystis occurs in advanced HIV with CD4 < 200 IV. Causes: Cavitary Lesions Pneumococcus Cryptococcus neoformans Rhodococcus equi (especially Pseudomonas) V

2015 FP Notebook

19. Gynecologic Manifestations of HIV

Gynecologic Manifestations of HIV Gynecologic Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Gynecologic (...) Manifestations of HIV Gynecologic Manifestations of HIV Aka: Gynecologic Manifestations of HIV , HIV related Gynecologic Complications II. Associated Conditions: Invasive Cervical Cancer (AIDS defining disease) Progressive enhances HPV replication HPV infection is very common in HIV HPV Implicated in and anal carcinoma Monitor high risk patient with every 6 months Women with <200 III. Associated Conditions: Infectious Vaginitis Occurs in 20-30% HIV infected women if >500 Recurrent in young women suggests HIV

2015 FP Notebook

20. Neurologic Manifestations of HIV

Neurologic Manifestations of HIV Neurologic Manifestations of HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Neurologic (...) Manifestations of HIV Neurologic Manifestations of HIV Aka: Neurologic Manifestations of HIV , HIV Related Neurologic Complications , HIV Infection with Neurologic Disease II. Epidemiology HIV patients with neurologic complications: 39-70% III. Symptoms: Common presentations s Focal neurological deficits See at time of seroconversion See CSF shows lymphocytic and high protein IV. Associated Conditions: Neurologic Primary Central Nervous System Presents with , blurred vision, s, personality or cognitive

2015 FP Notebook

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