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41. Occupational Therapy for people Undergoing total hip replacement

and successful interventions in the whole of medical practice. The success of hip replacement is entirely dependent upon a multidisciplinary team approach, with occupational therapy being a core part of its success. The updated guidance reflects changes in practice and in particular the requirement for reduction in length of stay. The trend for patients undergoing hip arthroplasty at younger ages continues, as does the increasing numbers of total hip replacements being performed year on year. National (...) then be developed and a treatment plan jointly agreed.The occupational therapy role 12 Occupational therapy for adults undergoing total hip replacement The home situation is discussed from the perspective that the service user is expert in this domain and their specific needs and choices. The service user can inform the occupational therapist about specific heights of their furniture (chair, bed and toilet) so that equipment may be prescribed to compensate for lack of function, or to enable activities

2018 Publication 1554

42. Integrating collaborative TB and HIV services within a comprehensive package of care for people who inject drugs

). • Guidelines for the programmatic management of drug-resistant tuberculosis – emergency update 2008 (7). • Guidelines for the psychosocially assisted pharmacological treatment of opioid dependence (8). • WHO policy on TB infection control in health-care facilities, congregate settings and households (9). • Guidelines for intensified tuberculosis case-finding and isoniazid preventive therapy for people living with HIV in resource-constrained settings (10). • mhGAP intervention guide for mental, neurological (...) services within a comprehensive package of care for people who inject drugs | Consolidated Guidelines I. Acronyms AIDS acquired immunodeficiency syndrome APRI aminotransferase/platelet ratio index ART antiretroviral therapy ASSIST Alcohol, Smoking and Substance Involvement Screening T est CHB chronic hepatitis B CI confidence interval CPT co-trimoxazole preventive therapy DAA direct-acting antiviral (drug) DIH drug-induced hepatotoxicity DNA deoxyribonucleic acid FIB-4 Fibrosis-4 score GRC Guideline

2016 World Health Organisation HIV Guidelines

43. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection

with men NASA national AIDS spending assessment NAT nucleic acid amplification testing NCD noncommunicable disease NNRTI non-nucleoside reverse-transcriptase inhibitor NRTI nucleoside reverse-transcriptase inhibitor NVP nevirapine OI opportunistic infection OST opioid substitution therapy PCP Pneumocystis jirovecii pneumonia PCR polymerase chain reaction PDR pre-treatment HIV drug resistance PEN Package of Essential NCD interventions PI protease inhibitor PITC provider-initiated testing and counselling (...) not so identified.xiii Definition of key terms Serodiscordant couples are couples in which one partner is living with HIV and the other is HIV-negative. A couple refers to two people in an ongoing sexual relationship; each of these people is referred to as a partner in the relationship. How individuals define their relationships will vary according to their cultural and social context. Antiretroviral therapy ARV (antiretroviral) drugs refer to the medicines used to treat HIV. ART (antiretroviral

2016 World Health Organisation HIV Guidelines

44. Biologic therapy for psoriasis

drugs in pregnancy and breastfeeding 21 British Association of Dermatologists guidelines for biologic therapy for psoriasis 2017 5 · The BTS guideline for managing TB in patients due to start anti-TNF-alpha treatment 22 · The BHIVA guidelines for routine investigation and monitoring of adult HIV-1-positive individuals 2016 23 · The 2016 EULAR updated guideline for the treatment of systemic sclerosis 24 3 Methods This guideline has been developed using the BAD recommended methodology 25 (...) non-biologic therapy approaches (for example inpatient topical therapy, phototherapy or standard systemic therapy) á When to consider dose escalation R22 Consider escalating the dose of biologic therapy in adults, where this is feasible and funded (see table) when an inadequate primary response may be due to insufficient drug dosing (for example, in people who are obese or whose psoriasis relapses during the treatment cycle). Take into account that this may be associated with an increased risk

2017 British Association of Dermatologists

45. Induction of labour: misoprostol vaginal delivery system

) for the induction of labour in women with an unfavourable cervix, from 36 weeks' gestation, in whom induction is clinically indicated. The manufacturer has advised that the UK launch is expected in quarter 4, 2014 (Ferring Pharmaceuticals: personal communication, January 2014). Currently, only short-acting oral preparations of misoprostol are available and none is licensed for the induction of labour in the UK. In practice, oral misoprostol tablets are sometimes administered vaginally to induce labour (...) that the UK launch is expected in quarter 4, 2014 (Ferring Pharmaceuticals: personal communication, January 2014). Currently, only short-acting oral preparations of misoprostol are available and none of these is licensed for the induction of labour in the UK. In practice, oral misoprostol tablets are sometimes Induction of labour: misoprostol vaginal delivery system (ESNM38) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page

2014 National Institute for Health and Clinical Excellence - Advice

46. March 2014 supplement to the 2013 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection

therapy 3. Pharmaceutical equivalence and clinical interchangeability between lamivudine and emtricitabine 4. Use of efavirenz during pregnancy as part of first-line antiretroviral therapy: a public health perspective 5. Optimizing antiretroviral drugs for children: medium- and long-term priorities 6. Changing role of CD4 cell counts in HIV care and treatment 7. Scaling up viral load testing in resource-limited settings Supplementary sections to Chapter 9 – Guidance on operations and service delivery (...) diagnosis coverage remains low, and this acts as one major bottleneck to improve the ART coverage among children. Within this context, and in accordance with the 2013 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection (1), The Global Plan towards the elimination of new HIV infections among children by 2015 and keeping their mothers alive (2) and the Treatment 2.0 Initiative (3), WHO convened an expert review meeting in September 2013 to evaluate emerging

2014 World Health Organisation HIV Guidelines

47. Preparing Emerging Leaders for Alternative Futures in Health Systems Across Canada

and linguistic minority populations); • occupation or labour-market experiences more generally (e.g., those in “precarious work” arrangements); • gender; • religion; • educational level (e.g., health literacy); • socio-economic status (e.g., economically disadvantaged populations); and • social capital/social exclusion. • The evidence brief strives to address all leaders, emerging leaders and potential future leaders, but (where possible) it also gives particular attention to people who have been (...) . This list is also not exhaustive and should act as a jumping-off point for deliberations about the ways in which the health system may change. The six expected futures are: 1) emerging leaders increasingly operate within a rapid-learning health-system orientation at all levels (self- management, clinical encounter, program, organization, sub-region, region and provincial/federal government); 2) emerging leaders are increasingly based in the home-and-community-care and primary-care sectors and more

2019 McMaster Health Forum

48. Daxas - roflumilast (medical review)

Daxas - roflumilast (medical review) CENTER FOR DRUG EVALUATION AND RESEARCH APPLICATION NUMBER: 022522Orig1s000 MEDICAL REVIEW(S) Summary Basis for Regulatory Action Date May 17, 2010 From Curtis J Rosebraugh, MD, MPH Director, Office of Drug Evaluation II Subject Summary Review NDA/BLA # Supp # 22-522 Applicant Name Nycomed/Forest Laboratories Proprietary / Established (USAN) Names Daxas roflumilast Dosage Forms / Strength Tablet 500 mcg Proposed Indication(s) Maintenance treatment of chronic (...) ) are main stays of therapy currently available for the treatment of COPD. Bronchodilators are used to treat the reversible bronchoconstriction associated with COPD. Many types of bronchodilators are available in the US for COPD, either as a single agent or in combination with ICS or a second bronchodilator of different mechanism. Examples of bronchodilators available include the short and the long-acting beta agonists such as albuterol, salmeterol, formoterol and the anti-muscarinic agents

2010 FDA - Drug Approval Package

49. Improving Cardiac Arrest Diagnostic Accuracy of Emergency Medical Dispatchers

: Cohort Time Perspective: Prospective Official Title: Improving the Cardiac Arrest Diagnostic Accuracy of 9-1-1 Emergency Medical Dispatchers Study Start Date : June 2013 Actual Primary Completion Date : September 2014 Actual Study Completion Date : December 2014 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Group/Cohort Intervention/treatment Training site All emergency medical dispatchers at a central ambulance communication centre in Ontario (...) % in Ontario. It has been shown that since the ambulance dispatch centres in Ontario implemented dispatch-assisted CPR instructions (given to callers while emergency vehicles were on the way), there was a significant increase in use. Emergency medical dispatchers can identify about 70% of OOHCA cases over the phone. Agonal breathing (laboured breathing preceding death) may be misinterpreted as a sign of life, and is responsible for as much as 50% of missed diagnoses. There is no specific training

2013 Clinical Trials

50. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection

approaches to HIV prevention to achieve maximum impact on reducing HIV transmission and acquisition. ART (ANTIRETROVIRAL THERAPY) ARV (antiretroviral) drugs refer to the medicines themselves and not to their use. ART refers to the use of a combination of three or more Ar V drugs to achieve viral suppression. This generally refers to lifelong treatment. Synonyms are combination Ar T and highly active Ar T. ART for prevention is used to describe the HIV prevention benefits of A r T. Eligible for ART refers (...) Library Cataloguing-in-Publication Data Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: r ecommendations for a public health approach June 2013. 1.HIV infections – drug therapy. 2.HIV infections – prevention and control. 3.Anti-r etroviral agents – therapeutic use. 4.Guideline. I.World Health Organization. ISBN 978 92 4 150572 7 (NLM classification: WC 503.2) © World Health Organization 2013 All rights reserved. Publications of the World Health

2013 World Health Organisation HIV Guidelines

51. 2012 Update to The Society of Thoracic Surgeons Guideline on Use of Antiplatelet Drugs in Patients Having Cardiac and Noncardiac Operations

options of patients exposed to anti- platelet drugs who need urgent operation. A. Search Methods The search methods used to survey the published liter- ature changed in the current guideline version compared with the previously published guideline [1]. In the inter- est of transparency, literature searches were conducted using standardized Medical Subject Heading (MeSH) terms from the National Library of Medicine PUBMED database list of search terms. The following terms com- prised the standard (...) doses of clopidogrel, it may be helpful to switch to another P2Y12 inhibitor (eg, prasugrel or ticagrelor). Class IIb (Level C) Treatment options for patients on antiplatelet drugs who require urgent operations For patients who require urgent operation while on dual antiplatelet therapy, delay of even a day or two before operation is reasonable to decrease bleeding risk and minimize thrombotic risk in patients with acute coronary syndromes. Class IIa (Level B) For patients on dual antiplatelet

2012 Society of Thoracic Surgeons

52. Guideline for Admission to Midwife-led Units in Northern Ireland & Northern Ireland Normal Labour & Birth Care Pathway

and agree. The guideline was also peer reviewed and informed by two Professors of Midwifery with expertise in the normalisation of labour and birth within MLU settings, an obstetrician and a midwife lecturer. Updating the Guideline In keeping with GAIN requirements these guidelines will be reviewed in 2018 or sooner in light of any emerging evidence. Funding The GDG was commissioned by GAIN to develop this guideline. 9 PLANNING PLACE OF BIRTH This guideline predominantly relates to women (...) with a straightforward singleton pregnancy (1) at the point of labour (2) . It is important to note that at each point of maternity care, all women should be assessed to ensure that they are receiving care from the most appropriate professional; that is, continue with midwife-led care (MLC), transfer to consultant-led care or transfer back to MLC (3) ; in particular, women who have been referred for investigation(s) or treatment which has been resolved. If there is any uncertainty, multidisciplinary discussion

2016 Regulation and Quality Improvement Authority

53. Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association Full Text available with Trip Pro

Induced pluripotent stem cells (iPSCs) offer an unprece-dented opportunity to study human physiology and disease at the cellular level. They also have the potential to be leveraged in the practice of precision medicine, for example, personalized drug testing. This statement comprehensively describes the provenance of iPSC lines, their use for cardiovascular disease modeling, their use for precision medicine, and strategies through which to promote their wider use for biomedical applications. Human (...) to (1) summarize the state of the science with respect to the use of iPSCs for modeling of cardiovascular traits and disorders and for therapeutic screening; (2) identify opportunities and challenges in the use of iPSCs for disease modeling and precision medicine; and (3) outline strategies that will facilitate the use of iPSCs for biomedical applications. This statement is not intended to address the use of stem cells as regenerative therapy, such as transplantation into the body to treat ischemic

2018 American Heart Association

54. Prevalence Survey of Antimalarial Drug Resistance Markers

of drug resistant malaria was a major factor contributing to the failure of the first global malaria eradication campaign in the mid-20th century (1). The widespread implementation of highly effective artemisinin-based combination therapy (ACT) for malaria has contributed to significant gains in global control and elimination efforts and has brought malaria eradication back on the agenda, 40 years after the first global malaria eradication campaign was abandoned (2). However the gains seen in the past (...) : Mahidol University Worldwide Antimalarial Resistance Network Mahidol Oxford Tropical Medicine Research Unit Myanmar Oxford Clinical Research Unit Shoklo Malaria Research Unit Lao-Oxford-Mahosot Hospital Wellcome Trust Research Unit Oxford University Clinical Research Unit, Vietnam Cambodia Oxford Medical Research Unit Information provided by (Responsible Party): University of Oxford Study Details Study Description Go to Brief Summary: Study is cross-sectional and observational with one-time dried

2017 Clinical Trials

55. Guideline on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV

to the medicines used to treat HIV. ART (antiretroviral therapy) refers to the use of a combination of three or more ARV drugs for treating HIV infection. ART involves lifelong treatment. Use of ARV drugs for HIV prevention refers to the HIV prevention benefits of ARV drugs and includes ARV drugs given to the mother or infant for preventing the mother-to-child transmission of HIV (PMTCT), ARV drugs to reduce the transmission of HIV among serodiscordant couples and ARV drugs to prevent people from acquiring HIV (...) 2015WHO Library Cataloguing-in-Publication Data Guideline on when to start antiretroviral therapy and on pre-exposure prophylaxis for HIV. 1.HIV Infections – drug therapy. 2.Anti-Retroviral Agents – administration and dosage. 3.Anti-Retroviral agents – therapeutic use. 4.Time-to-Treatment. 5.Guideline. I.World Health Organization. ISBN 978 92 4 150956 5 (NLM classification: WC 503.2) © World Health Organization 2015 All rights reserved. Publications of the World Health Organization are available

2015 World Health Organisation HIV Guidelines

56. Core Competencies for Management of Labour

, obstetrical, medical, surgical, psycho- social, religious, spiritual and cultural factors • Risk factors for maternal/ fetal complications • Social determinants of health and their impact on access to care and perinatal outcomes • Process and stages of normal labour and birth • Process of initiation of breastfeeding • Assessment for urgent and emergent conditions • Protecting and supporting the normal labour and birth process • Providing evidenced based care • Identifying psychosocial support needs (...) • Monitoring woman’s response to pain relief options • Administering appropriate medications/ treatment • Collecting specimens, and interpreting laboratory data • Initiating intravenous access • Facilitating breastfeeding initiation and maternal- newborn interaction • Performing neonatal resuscitation • Advocating for spontaneous labour • Ensuring freedom of movement as a means of promoting normal labour • Recognizing indications for and the effects of non-pharmacological or pharmacological pain relief

2014 British Columbia Perinatal Health Program

57. Antimicrobial stewardship: systems and processes for effective antimicrobial medicine use

(including antibiotics) in children, young people and adults. It aims to change prescribing practice to help slow the emergence of antimicrobial resistance and ensure that antimicrobials remain an effective treatment for infection. Who is it for? Health and social care practitioners Organisations commissioning, providing or supporting the provision of care People who are taking antimicrobials and their families and carers. Antimicrobial stewardship: systems and processes for effective antimicrobial (...) ). Page 6 of 25P Person-centred care erson-centred care This guideline offers best practice advice on the effective use of antimicrobial medicines. Patients and health professionals have rights and responsibilities as set out in the NHS Constitution for England – all NICE guidance is written to reflect these. Treatment and care should take into account individual needs and preferences. Patients should have the opportunity to make informed decisions about their care and treatment, in partnership

2015 National Institute for Health and Clinical Excellence - Clinical Guidelines

58. Cash?based approaches in humanitarian emergencies: a systematic review Full Text available with Trip Pro

Cash?based approaches in humanitarian emergencies: a systematic review Cash‐based approaches in humanitarian emergencies: a systematic review - Doocy - 2017 - Campbell Systematic Reviews - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term SYSTEMATIC REVIEW Open Access Cash‐based approaches in humanitarian emergencies: a systematic review Corresponding Author Corresponding author Shannon Doocy Johns (...) and Conditions of Use. Shareable Link Use the link below to share a full-text version of this article with your friends and colleagues. Copy URL Share a link Share on ). In addition, violent conflict affects the lives of roughly 1.5 billion people across the globe every year (World Bank, 2011). Although some crises can be directly attributed to a single, distinct event that occurs with little or no warning, most emergencies are complex, protracted and chronic, evolving from a series of related or unrelated

2017 Campbell Collaboration

59. Immediate Postpartum Long-Acting Reversible Contraception

Immediate Postpartum Long-Acting Reversible Contraception Immediate Postpartum Long-Acting Reversible Contraception - ACOG Menu ▼ Immediate Postpartum Long-Acting Reversible Contraception Page Navigation ▼ Number 670, August 2016 (Reaffirmed 2018) Committee on Obstetric Practice The American College of Nurse–Midwives and the Society for Maternal–Fetal Medicine endorse this document. The American Academy of Family Physicians and the Association of Women’s Health, Obstetric and Neonatal Nurses (...) support this document. This Committee Opinion was developed by the American College of Obstetricians and Gynecologists’ Committee on Obstetric Practice in collaboration with committee members Ann E. Borders, MD, MSc, MPH and Alison M. Stuebe, MD, MSc, and reviewed by the Long-Acting Reversible Contraception Work Group. This document reflects emerging clinical and scientific advances as of the date issued and is subject to change. The information should not be construed as dictating an exclusive course

2016 American College of Obstetricians and Gynecologists

60. Regional Models of Care for Systemic Treatment: Standards for the Organization and Delivery of Systemic Treatment

care at all times, including during vacation, illness, etc.* ? Cancer care includes the management of symptoms and complications of therapy and oncological emergencies.* ? Follow regulatory guidelines and standards for the safe handling and disposal of hazardous drugs including personal protective equipment and training for staff who are handling systemic treatment or waste.* For additional information, please see Appendix 1 #25. ? Centres have policies and educational programs available for all (...) Technicians, Institute for Safe Medication Practices Canada, CCO (Systemic Treatment Program & PDRP), and Canadian Council on Continuing Education in Pharmacy Ontario Public Drug Programs: Patients for Patient Safety Canada, Ontario Hospital Association, College of Physicians and Surgeons of Ontario, Innovative Medicines Canada and Health Quality Ontario References from identified documents were also searched. Given the breadth of the information identified by this approach, the selection of documents

2019 Cancer Care Ontario

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