How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

60 results for

Emergency Pediatric Dosing 6-7 kilogram


Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

1. Emergency Pediatric Dosing 6-7 kilogram

- Childrens Hospital, Pediatric Emergency Drug Guide Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Emergency Pediatric Dosing 6-7 kilogram." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Pharmacology About is a rapid access, point-of-care medical reference for primary care and emergency clinicians. Started in 1995 (...) Emergency Pediatric Dosing 6-7 kilogram Emergency Pediatric Dosing 6-7 kilogram Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4

2018 FP Notebook

2. Emergency Pediatric Dosing 6-7 kilogram

- Childrens Hospital, Pediatric Emergency Drug Guide Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Emergency Pediatric Dosing 6-7 kilogram." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Pharmacology About is a rapid access, point-of-care medical reference for primary care and emergency clinicians. Started in 1995 (...) Emergency Pediatric Dosing 6-7 kilogram Emergency Pediatric Dosing 6-7 kilogram Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4

2015 FP Notebook

3. A Safety and Tolerability Study of GSK2982772, in Single (in Both Fed and Fasted States) and Repeat Oral Doses in Healthy Male Subjects

), time to maximum observed blood drug concentration (Tmax), and terminal half-life (t1/2) following single (fed and fasted) doses, where data allow Composite of derived blood PK parameters of GSK2982772 measured by AUC (0-t), AUC (0-infinity), AUC (0-tau), Cmax, Tmax and t1/2,following repeat doses [ Time Frame: Pre-dose, Days 1 (20 and 40 minutes, 1, 1.5, 2, 3, 5, 8, 10 and 12 hours) , 2, 3, 4, 5, 6, 7, 14 (20 and 40 minutes, 1, 1.5, 2, 3, 5, 8, 10 and 12 hours), 15 and 16 post-dose ] Derived blood (...) for inclusion into the study at the discretion of the Investigator. Body weight >= 50 kilogram (kg) and body mass index (BMI) within the range 19 - 30 (kilogram/squared meter) kg/m^2 (inclusive). Male subjects with female partners of child bearing potential must comply with the following contraception requirements from the time of first dose of study medication until at least five half-lives of study medication after the last dose of study medication or the follow-up visit, whichever is longer

2014 Clinical Trials

4. First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update

in raw measure of kilograms (kg) and kg·m -2 , which led to higher values used for between-group differences in weight and BMI: mean weight change for lurasidone (doses pooled) versus placebo was 0.45 kg not 2.67 kg, and mean change in BMI was 0.15 kg·m -2 rather than 2.92 kg·m -2 . We updated the following analyses for Key Question 2 about the effect of olanzapine compared with lurasidone on weight gain and BMI: network meta-analysis for body composition outcomes across all conditions; analysis (...) , Feinstein Institute for Medical Research Glen Oaks, NY Jana Davidson, M.D., FRCPC Psychiatrist-in-Chief, B.C. Children’s Hospital, PHSA Clinical Professor, Psychiatry Head, Division of Child & Adolescent Psychiatry at University of British Columbia Vancouver, BC, Canada Gregory Gale, M.D. Medical Director, Behavioral Health LifeSynch-HUMANA Irving, TX Michael Naylor, M.D. Director, Behavioral Health and Welfare Program Director, Comprehensive Assessment and Response Training System vi Director, Clinical

2017 Effective Health Care Program (AHRQ)

5. Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures

and inhalation sedation agents and the duration of their admin- istration shall be documented. Before drug administration, special attention must be paid to the calculation of dosage (i.e., mg/kg); for obese patients, most drug doses should likely be adjusted lower to ideal body weight rather than actual weight. 345 When a programmable pump is used for the in- fusion of sedating medications, the dose/kilogram per minute or hour and the child’s weight in kilograms should be double- checked and confirmed (...) sedation). However, if a deeply sedated child requires intervention for airway obstruc- tion, apnea, or laryngospasm, there is concern that these rescue maneuvers could increase the risk of pulmonary aspiration of gastric contents. For children requiring urgent/emergent sedation who do not meet elective fasting guidelines, the risks of sedation and possible aspiration are as-yet unknown and must be balanced against the benefits of performing the procedure promptly. For example, a prudent practitioner

2016 American Academy of Pediatric Dentistry

6. Preschool Multiple-Breath Washout Testing: A Technical Statement

encountered when using these commercially available devices with preschool children need to be considered by manufacturers, as well as researchers/clinicians. Higher respiratory rates, lower respiratory ?ows, and lower lung volumes in preschool children place additional demands on equipment performance. This may account for the lower accuracy observed against smaller lungmodelvolumesinsomeoftheprevious validation efforts in the literature (6, 7). Success in the infant age range illustrates that these can (...) by smaller working groups, merged in the overall draft document by the chair, and all authors provided comment and suggestions for the ?nal document. The methods checklist is presented in Table 3. Background Publications including pediatric MBW testing initially emerged in the 1960s (21, 22), whereas the inclusion of preschool children in studies did not occur until two decades later (23, 24). Initial data collected in the 1980s suggested poor feasibility in preschool children. Using custom-built

2018 American Thoracic Society

7. Infective Endocarditis in Childhood: 2015 Update Full Text available with Trip Pro

, with specific attention to the disease as it affects infants and children. In particular, the impact of increased survival for children with congenital heart disease (CHD) on the epidemiology of IE is updated, and newer tools useful for diagnosis and treatment in the pediatric population are reviewed. This review emphasizes changing management perspectives and discussion of new agents that have utility for treatment of resistant organisms. In addition, proper use of the diagnostic microbiology laboratory (...) Association (AHA) published “Unique Features of Infective Endocarditis in Childhood,” which reviewed epidemiology, pathogenesis, diagnosis, clinical and laboratory findings, treatment, and prevention of infective endocarditis (IE) with particular attention to children. Since that time, other AHA reports have focused on new recommendations for treatment of IE in adults (in 2005 ) and on major changes regarding prevention of IE (in 2007 ). This document updates these issues and other concerns regarding IE

2015 American Heart Association

8. Janus Kinase Inhibitors and Biosimilars for Rheumatoid Arthritis: Effectiveness and Value

be aware that new evidence may emerge following the publication of this report that could potentially influence the results. ICER may revisit its analyses in a formal update to this report in the future. The economic models used in ICER reports are intended to compare the clinical outcomes, expected costs, and cost effectiveness of different care pathways for broad groups of patients. Model results therefore represent average findings across patients and should not be presumed to represent the clinical (...) are different. A proposed biosimilar must have the same mechanism of action for the intended condition(s) of use as the reference product. The route of administration, dose form, and strength must also be the same. Of note, once a biosimilar has been approved, it may be prescribed for any indication allowed for the reference product, even if the biosimilar has not been studied in that patient population. 29 Biosimilar naming follows a standard approach. Each nonproprietary name for a biological product

2020 California Technology Assessment Forum

9. Programmatic management of latent tuberculosis infection in the European Union

-resistant TB) • Risk of progression to active TB over time in infected persons, with or without LTBI treatment • Cost of LTBI in the EU/EEA • Identification of the most reliable tests for diagnosis of LTBI with the highest yield in different epidemiological settings (e.g. high and low TB burden) and populations (e.g. immunocompromised patients, children, migrants and close contacts of TB patients) • The effect of tests being free of charge • Assessment of strategies for improved screening and case

2019 European Centre for Disease Prevention and Control - Public Health Guidance

10. Management of Stillbirth

of cervical Bishop score , although high-dose oxytocin infusion also is an acceptable choice . A meta-analysis of 14 randomized controlled trials that evaluated methods of induction for second and third trimester stillbirth demonstrated that both vaginal and oral misoprostol regimens were 100% effective in achieving uterine evacuation within 48 hours . Dose regimens and frequency of administration differed in the included trials, which makes direct comparisons of dose strategy challenging. Based (...) on limited evidence, before 28 weeks of gestation, typical dosages for misoprostol are 400–600 micrograms vaginally every 3–6 hours. Doses less than 400 micrograms have decreased efficacy . After 28 weeks of gestation, induction of labor should be managed according to usual obstetric protocols. There is high-quality evidence to support the use of mifepristone plus misoprostol for management of pregnancy loss before 20 weeks when compared to misoprostol alone . Data regarding the use of mifepristone

2020 American College of Obstetricians and Gynecologists

11. Registries for Evaluating Patient Outcomes: A User's Guide

and apply the best evidence for the collaborative healthcare choices of each patient and provider; to drive the process of discovery as a natural outgrowth of patient care; and to ensure innovation, quality, safety, and value in healthcare.’ 5 Within a learning health system, registries can support population health management, clinical decision making, quality improvement, and clinical research. 6, 7 However, registries must be connected to other registries, EHRs, and other data sources in order (...) ) with the purpose of presenting new, emerging themes related to designing and conducting registries. First published in 2007, the User’s Guide, with translations available in Chinese and Korean, serves as a reference for planning, developing, maintaining, and evaluating registries designed to collect data about patient outcomes. The second (2010) and third (2014) editions incorporated updates to existing topics and included new chapters on methodological and technological advances in registry science. The first

2019 Effective Health Care Program (AHRQ)

12. Heart Disease and Stroke Statistics Full Text available with Trip Pro

tax was greatest among households of the lowest socioeconomic status. A similar 1 cent per ounce excise tax on SSBs was implemented in Berkeley, California, in January 2015, and SSB sales declined by 9.6% after 1 year compared with predicted SSB purchases based on pretax trends. The Special Supplemental Nutrition Program for Women, Infants, and Children food package was revised in 2009 to include more fruits, vegetables, whole grains, and lower-fat milk. These food package revisions were (...) after myocardial infarction (MI), lower risk of atrial fibrillation, and greater positive psychological functioning (dispositional optimism). Among children, from 1999 to 2000 to 2015 to 2016, prevalence of nonsmoking, ideal total cholesterol, and ideal BP improved. For example, nonsmoking among children aged 12 to 19 years went from 76% to 94%. However, meeting ideal levels for physical activity, body mass index (BMI), and blood glucose did not improve. For example, prevalence of ideal BMI declined

2019 American Heart Association

13. Clinical Practice Guidelines for the Perioperative Nutrition, Metabolic, and Nonsurgical Support of Patients Undergoing Bariatric Procedures

Examination Survey (NHANES) 2013–2016 dataset, 38.9% of US adults and 18.5% of youth aged 2–19 years had obesity (6, 7). This translates into 93.3 million adults and 13.7 million children and youth, respectively. More women (40.8%) than men (36.5%) were obese, with non-Hispanic black women (55.9%) showing the highest rates of prevalence (6, 7). Although the prevalence of obesity has been steady among adults since 2011–2012, rates of prevalence in certain subpopulations continue to rise, particularly (...) substantially. Studies have demonstrated that bariatric/metabolic surgery achieves superior improvements in glycemic control of patients with type 2 diabetes and obesity, compared with various medical and lifestyle interventions, and leads to substantial cost savings. Improved cardiovascular outcomes and quality of life have also been reported in patients undergoing bariatric surgery. New and emerging surgical and nonsurgical bariatric procedures are described. Criteria for bariatric procedures are better

2019 American Association of Clinical Endocrinologists

14. WHO Guidelines for the pharmacological and radiotherapeutic management of cancer pain in adults and adolescents

, dosage and dosing intervals. Patients should be warned about possible adverse effects of each of the medicines they are being given. 5.7. CANCER PAIN MANAGEMENT SHOULD BE INTEGRATED AS PART OF CANCER CARE Cancer pain management should be integrated into cancer treatment plans throughout the care continuum, including when a patient’s disease is not terminal, as necessary. Treatment should begin by giving the patient an understandable explanation of the causes of the pain. Anti-cancer treatment (...) factors for improper use and signs of substance use disorders that should influence clinical decision-making. The presence of opioids in households presents a risk of misuse or unintentional over- dose by children, adolescents and other household members. Safe, secure storage of opioid analgesics should be optimized at household level and provision made for the safe disposal or return of unused opioid medicines to a pharmacy at the end of life or when no longer needed. 5.4. A PAIN MANAGEMENT PLAN

2019 World Health Organisation Guidelines

15. Management Of Haemophilia

. Nor Hasni Haron Senior Principal Assistant Director Pharmaceutical Care Section Pharmacy Practice & Development Division MoH, Selangor Mr. Peit De Klient Physiotherapist UMC Utrecht Department of Rehabilitation Utrecht, Netherlands Dr. Ri Liesner Consultant in Paediatric Haemostasis and Thrombosis Great Ormond Street Hospital for Children London, United Kingdom Dr. Ridzuan Dato’ Isa Head of Department & Emergency Physician Hospital Ampang, Selangor Dr. Siti Zaleha Suleiman Family Medicine (...) • easy bruising in early childhood • ‘spontaneous’ bleeding particularly into the soft tissues, muscles, joints and gums • excessive bleeding following trauma or surgery A newborn or infant with haemophilia can present with spontaneous intracranial bleed. A child may also present with post-vaccination or vitamin K injection haematoma. A positive family history is present in two-thirds of patients while another one-third may have spontaneous mutation. 2 The most common site of bleeding in haemophilia

2018 Ministry of Health, Malaysia

16. Management of Pregnancy

Gestational Age at Birth Outcomes Preterm 41 6/7 weeks Increased risk of adverse neonatal outcomes compared to full-term infants B. Epidemiology and Impact in the General Population a. Rates of Reproduction In 2014, there were 3,978,497 registered births in the United States (U.S.).[ ] In general, between 1990 and 2014, rates of reproduction in the U.S. have decreased.[ ] Women have also been giving birth at later ages. Mean age at first delivery increased from 24.9 years in 2000 to 26.3 years in 2014 (...) . Changes were most pronounced between 2009 and 2014.[ ] There are many possible drivers for the decrease in rates of reproduction in the past few decades and the increasing number of deliveries later in women’s lives, such as women’s increasing prioritization on education and establishing careers prior to having children and improved access to contraception and reproductive health services. 6 7 8 b. Pregnancy Complications Although there have been advances in medicine and medical technologies over

2018 VA/DoD Clinical Practice Guidelines

17. Psychological and Pharmacological Treatments for Adults With Posttraumatic Stress Disorder: A Systematic Review Update

= 0.3233 G2 vs. G3, p = 0.5396 NR F-218 Author Year Intervention Groups Subgroup Analyzed Comorbid Condition QOL Disability/Function al Impairment Return to Work/Duty Resick et al., 2002 3 Resick et al., 2003 125 Resick et al., 2012 126 G1: CBT, CPT G2: CBT, exposure- based therapy (PE) G3: WL Exposure to Child Trauma BDI Mean (SD) No Childhood Sexual Abuse Pre-tx: 22.4 (9.5) Post-tx: 10.0 (8.3) 9 mth FU: 10.9 (9.1) Childhood Sexual Abuse Pre-tx: 24.9 (9.1) Post-tx: 11.4 (10.4) 9 mth FU: 12.9 (12.7

2018 Effective Health Care Program (AHRQ)

18. Tofacitinib (Xeljanz) - Rheumatoid arthritis

are: Tablet core: microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, and magnesium stearate. Film coat: hypromellose 6cP (E464), titanium dioxide (E171), lactose monohydrate, macrogol 3350, and triacetin (E1518) The product is available in HDPE bottles with silica gel desiccant and child-resistant caps and aluminium foil/PVC backed aluminium foil unit dose blisters as described in section 6.5 of the SmPC. 2.2.2. Active Substance General information The chemical name of tofacitinib (...) bottles with silica gel desiccant and child-resistant caps or aluminium foil/PVC backed aluminium foil unit dose blisters. The material complies with Ph.Eur. and EC requirements. The choice of the container closure system has been validated by stability data and is adequate for the intended use of the product. Manufacture of the product and process controls The manufacturing process consists of 10 main steps. In summary, the excipients are blended, dry granulated and then compressed to form the tablet

2017 European Medicines Agency - EPARs

19. Management of Uterine Fibroids

embolism (UAE) reduce fibroid size, and improve symptoms and quality of life. High intensity focused ultrasound reduces fibroid size, but impact on quality of life was not measured. Myomectomy and hysterectomy also improve quality of life. Direct comparisons of interventions provide little evidence. • For women in their 30s, the chance of needing retreatment for fibroids within the next 2 years was 67 percent after medical treatment or myomectomy and 44 percent after UAE. For older women, the chance (...) Hehenkamp W et al. (2007) 97 79 1.4 10/79 (13.0) 78 6 7/78 (9.0) 74 12 9/74 (12.0) 80 (US) 24 14/80 (18.0) Rashid S et al. (2010) 82 62 (US) 12 7/62 (11.0) Mara M et al. (2008) 21 58 (US) 6 8/58 (13.8) Anti-Mullerian hormone Hehenkamp W et al. (2007) 97 79 1.4 - 0.62 a 78 6 - 0.23 a 74 12 - 0.31 a 80 (US) 24 - 0.42 a Pregnancy Edwards R et al. (2007) 104 95 (MRI) 12 7/95 (7.4) Volkers N et al. (2007) 99 81 (US) 24 1/81 (1.2) Mara M et al. (2008) 21 26 (US/MRI) 24 13/26 (50.0) FSH = follicle stimulating

2017 Effective Health Care Program (AHRQ)

20. Heart Disease and Stroke Statistics 2017 Update: A Report From the American Heart Association Full Text available with Trip Pro

Cardiac Arrest (Chapter 18) • In the 2015 CARES (Cardiac Arrest Registry to Enhance Survival) National Survival Report for emergency medical services–treated nontrau- matic cardiac arrest, the survival rate to hospital discharge was 10.6% for adults >18 years old, 23.5% for children 13 to 18 years old, 16.6% for children >1 to 12 years old, and 6.2% for children 0. • Coronary artery calcium scores >400 versus 0 are associated with an increased risk for can- cer, chronic kidney disease, pneumonia (...) Sandeep R. Das University of Texas Southwestern Medical Center None None None None None None None Rajat Deo University of Pennsylvania NIH† None None None None Boehringer Ingelheim*; Janssen Pharmaceuticals* None Sarah D. de Ferranti Children's Hospital Boston Pediatric Heart Network, NHLBI (coPI on upcoming pediatric prevention trial)* None None None None None None James Floyd University of Washington None None None None None None None Myriam Fornage University of Texas Health Science Center

2017 American Heart Association

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>