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Embryology

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101. Evidence-based medicine and its application in clinical preimplantation embryology. (PubMed)

Evidence-based medicine and its application in clinical preimplantation embryology. The randomized clinical trial (RCT) was developed to assess the efficacy of medical interventions by comparing a treatment group with a control group that did not receive treatment or received placebo. It has been evident that this study design is more suited to evaluation of drugs and less to complex interventions such as surgical procedures. The same can be said about assisted reproduction technology, which (...) clearly belongs in the complex category. Yet, there have been no specific guidelines for the design of RCT in clinical embryology. Moreover, the reliability of the published data from arbitrarily designed trials has not been debated. The near absence of allocation concealment and blinding and the difficulties inherent in randomizing oocytes and embryos in addition to patients require further consideration. This work evaluates systematic reviews to assess the efficacy of interventions, including

2013 Reproductive biomedicine online

102. New approaches under development: cardiovascular embryology applied to heart disease (PubMed)

New approaches under development: cardiovascular embryology applied to heart disease Despite many innovative advances in cardiology over the past 50 years, heart disease remains a major killer. The steady progress that continues to be made in diagnostics and therapeutics is offset by the cardiovascular consequences of the growing epidemics of obesity and diabetes. Truly innovative approaches on the horizon have been greatly influenced by new insights in cardiovascular development. In particular

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2013 The Journal of clinical investigation

103. Supernumerary Renal Arteries and Their Embryological and Clinical Correlation: A Cadaveric Study from North India (PubMed)

Supernumerary Renal Arteries and Their Embryological and Clinical Correlation: A Cadaveric Study from North India Background. Classically, each kidney is supplied by a single renal artery originating from abdominal aorta. The present study aimed at its variations and their embryological and clinical correlation. Material and Methods. The formalin-fixed thirty-seven cadavers from north India constituted the material for the study. During routine abdominal dissection conducted for medical

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2013 ISRN anatomy

104. Can the Pathogenesis of Auditory Ossicular Malformations be Explained by the Branchial-Based Theory?-Evaluation by the Consecutive Distribution of Embryologic Foci in 87 Cases. (PubMed)

Can the Pathogenesis of Auditory Ossicular Malformations be Explained by the Branchial-Based Theory?-Evaluation by the Consecutive Distribution of Embryologic Foci in 87 Cases. Development of the auditory ossicles is initiated by induction of the cartilage primordium of each ossicle between the fifth and seventh fetal week. It is well known that primordium of the upper part of the ossicular chain is derived from the first branchial arch and that of the lower part develops from the second (...) branchial arch. Previous studies have suggested that auditory ossicular malformations are caused by deficiencies in the early period of induction of the cartilage primordium. However, auditory ossicular malformations can occur at any developing stage, and their clinical features are very complicated.The precise embryologic foci of auditory ossicular malformations were estimated by evaluating the consecutive distribution of these anomalies, and the pathogenesis of these malformations was discussed using

2013 Otology and Neurotology

105. A rudimentary tragus in the nasopharynx: Case report, literature review, and discussion of embryologic development. (PubMed)

A rudimentary tragus in the nasopharynx: Case report, literature review, and discussion of embryologic development. We describe the rare case of a nine year-old girl with a several month history of mouth breathing and nasal obstruction due to a rudimentary tragus in the nasopharynx. We focus on the accessory tragus and its origins by describing the embryologic development of the external ear. Based on our review of the medical literature, this is the first report of a nasopharyngeal mass

2013 International Journal of Pediatric Otorhinolaryngology

106. Embryologic innervation of the rat laryngeal musculature-a model for investigation of recurrent laryngeal nerve reinnervation. (PubMed)

Embryologic innervation of the rat laryngeal musculature-a model for investigation of recurrent laryngeal nerve reinnervation. Optimal management of vocal fold paralysis would entail recurrent laryngeal nerve (RLN) reinnervation resulting in normal vocal fold motion. Unfortunately, RLN reinnervation currently results in a nonfunctional vocal fold due to synkinetic reinnervation. Therapeutic interventions that guide regenerating axons back to the appropriate muscle would prevent synkinesis (...) and restore vocal fold and glottal function. The initial step toward developing these therapies is the elucidation of the embryologic innervation of the larynx. This study aimed to identify the age of occurrence, timing, and pattern of embryologic innervation of the rat larynx, hypothesizing that differences in these parameters exist between distinct laryngeal muscles.Descriptive anatomic study.The larynx of rats aged embryologic day (E) 15, 16, 17, 19, and 21 were harvested and then sectioned. Two rats

2013 Laryngoscope

107. An Update on Embryology of the Upper Limb. (PubMed)

An Update on Embryology of the Upper Limb. Current concepts in the steps of upper limb development and the way the limb is patterned along its 3 spatial axes are reviewed. Finally, the embryogenesis of various congenital hand anomalies is delineated with an emphasis on the pathogenetic basis for each anomaly. Copyright © 2013 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

2013 Journal of Hand Surgery - American

108. Embryological-Origin-Dependent Differences in Hox Expression in Adult Aorta: Role in Regional Phenotypic Variability and Regulation of NF-κB Activity. (PubMed)

Embryological-Origin-Dependent Differences in Hox Expression in Adult Aorta: Role in Regional Phenotypic Variability and Regulation of NF-κB Activity. Different vascular beds show differing susceptibility to the development of atherosclerosis, but the molecular mechanisms underlying these differences are incompletely understood. This study aims to identify factors that contribute to the phenotypic heterogeneity of distinct regions of the adult vasculature.High-throughput mRNA profiling in adult

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2013 Thrombosis and Vascular Biology

109. Embryology of familial (non-syndromic) brachydactyly of the hand. (PubMed)

Embryology of familial (non-syndromic) brachydactyly of the hand. Isolated familial non-syndromic brachydactyly is interesting from the embryological point of view because the phenotypes of isolated brachydactyly are frequently overlapping, yet they are caused by different gene mutations and the ring finger is frequently relatively preserved. We review the embryology of isolated familial brachydactyly with special attention to these two features. © The Author(s) 2013.

2013 Journal of Hand Surgery - European

110. Divided nevus of the eyelid: Review of embryology, pathology and treatment. (PubMed)

Divided nevus of the eyelid: Review of embryology, pathology and treatment. Divided nevus, which is also known as "kissing nevus," "split ocular nevus" and "panda nevus" is a rare congenital dermatological abnormality that occurs on opposing margins of upper and lower eyelids. There is a paucity of literature on this rare anomaly, with most knowledge from this disease process derived from isolated case reports and series. The purpose of this study is to report a new case of divided nevus (...) of the eyelid and to discuss the unique embryology, pathology, and potential treatment options for this rare entity. A systematic review of literature was performed of the English literature on PubMed and Medline with just under 150 cases reported in the literature. The vast majority of the divided nevi seen in this review were medium sized and of the melanocytic intradermal type. There were no described cases of malignant transformation in any of the documented cases. Numerous methods for reconstruction

2013 American Journal of Otolaryngology

111. Embryology in the era of proteomics. (PubMed)

Embryology in the era of proteomics. Proteomic technologies have begun providing evidence that viable embryos possess unique protein profiles. Some of these potential protein biomarkers have been identified as extracellular and could be used in the development of a noninvasive quantitative method for embryo assessment. The field of assisted reproductive technologies would benefit from defining the human embryonic proteome and secretome, thereby expanding our current knowledge of embryonic

2013 Fertility and Sterility

112. Embryology of the heart and its impact on understanding fetal and neonatal heart disease. (PubMed)

Embryology of the heart and its impact on understanding fetal and neonatal heart disease. Heart development is a complex process during which the heart needs to transform from a single tube towards a fully septated heart with four chambers and a separated outflow tract. Several major events contribute to this process, that largely overlap in time. Abnormal heart development results in congenital heart disease, which has an estimated incidence of 1% of liveborn children. Eighty percent of cases

2013 Seminars in fetal & neonatal medicine

113. Astrocytes reassessment - an evolving concept part one: embryology, biology, morphology and reactivity (PubMed)

Astrocytes reassessment - an evolving concept part one: embryology, biology, morphology and reactivity The goal of this review is to integrate - in its two parts - the considerable amount of information that has accumulated during these recent years over the morphology, biology and functions of astrocytes - first part - and to illustrate the active role of these cells in pathophysiological processes implicated in various psychiatric and neurologic disorders - second part.

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2013 Journal of Molecular Psychiatry

114. Gallbladder agenesis with choledochal cyst—a rare association: a case report and review of possible genetic or embryological links (PubMed)

Gallbladder agenesis with choledochal cyst—a rare association: a case report and review of possible genetic or embryological links Gallbladder agenesis is a rare congenital anomaly. Choledochal cysts are uncommon. The combination of both these entities in a 56-year-old woman is reported. A previously fit and well woman, presented to the emergency department with a 3-day history of abdominal pain. Preoperative imaging and intraoperative findings confirmed gallbladder agenesis and a type I

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2013 BMJ case reports

115. Unilateral Rete Mirabile as a Result of Segmental Agenesis of the Ascending Petrous Segment of the Internal Carotid Artery: Embryology, Differential Diagnosis and Clinical Implications (PubMed)

Unilateral Rete Mirabile as a Result of Segmental Agenesis of the Ascending Petrous Segment of the Internal Carotid Artery: Embryology, Differential Diagnosis and Clinical Implications We describe an extremely rare case of unilateral rete mirabile in a young woman and discuss its significance in embryological development as well as its radiological aspects, differential diagnosis and potential clinical implications.

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2013 Interventional Neuroradiology

116. Giant epignathus with midline mandibular cleft: Insights in embryology and management (PubMed)

Giant epignathus with midline mandibular cleft: Insights in embryology and management A congenital teratoid tumor arising and protruding through the mouth is classified as epignathus or fetus in fetu. On review of literature, we found various reports of midline mandibular and lower lip cleft associated with flexion contracture of neck, midline cervical cord, but there is only one report of association with midline dermoid. We present an unusual case of midline cleft of mandible (...) showed a rounded soft tissue mass arising from the alveolus with multiple calcifications within it along with a large triangular calcification and absence of hyoid bone. The mass was excised by mobilizing the tip of tongue. Staged repair was planned for the defect in the mandible. Unfortunately, the baby succumbed postoperatively to complex congenital heart disease. Histopathology was suggestive of epignathus. We discuss hereby the embryology and current management strategies of the problem.

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2012 Annals of maxillofacial surgery

117. The Radiological Manifestations of the Aberrant Air Surrounding the Pleura: In the Embryological View (PubMed)

The Radiological Manifestations of the Aberrant Air Surrounding the Pleura: In the Embryological View The radiological manifestations of the aberrant air surrounding the pleura are varied because of the air outlining the organs in and out of the visceral space. The continuity of the visceral space from the neck, mediastinum to the retroperitoneum is originated from embryological development, which is compatible with the findings through laboratory experiments, cadaveric anatomy, and thoracic

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2012 Pulmonary medicine

118. Spiral cleavage and early embryology of a loxosomatid entoproct and the usefulness of spiralian apical cross patterns for phylogenetic inferences (PubMed)

Spiral cleavage and early embryology of a loxosomatid entoproct and the usefulness of spiralian apical cross patterns for phylogenetic inferences Among the four major bilaterian clades, Deuterostomia, Acoelomorpha, Ecdysozoa, and Lophotrochozoa, the latter shows an astonishing diversity of bodyplans. While the largest lophotrochozoan assemblage, the Spiralia, which at least comprises Annelida, Mollusca, Entoprocta, Platyhelminthes, and Nemertea, show a spiral cleavage pattern, Ectoprocta

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2012 BMC developmental biology

119. Embryology

Embryology Embryology Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Embryology Embryology Aka: Embryology , Embryo Organ Development (...) are a random sampling from a Bing search on the term "Embryology." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: embryologic (C0013943) Definition (MSH) Used with organs, regions, and animal headings for embryologic and fetal development. It is used also with diseases for embryologic factors contributing to postnatal disorders. Concepts Functional Concept ( T169 ) MSH English EMBRYOL , EM , embryologic , embryology

2015 FP Notebook

120. Should a single blastocyst transfer policy be a clinical decision or should it depend on the embryological evaluation on day 3? (PubMed)

Should a single blastocyst transfer policy be a clinical decision or should it depend on the embryological evaluation on day 3? Single blastocyst transfer has the advantage of maximizing the fresh single pregnancy rate. However, in patients with a low number of good quality embryos on day 3, it remains unclear whether immediate embryo transfer or further embryo culture with blastocyst transfer is the most preferable option.A retrospective cohort study was carried out in which the outcome of 590 (...) fresh in vitro fertilization (IVF) cycles over a 15 months period and their cryo cycles were analyzed. A total of 341 patients cycles had an elective day 5 strategy independent of intermediate embryo evaluation while another 249 patients underwent a day 5 embryo transfer only if at least four embryos were available on day 3. Blastocyst vitrification was performed using a closed high security system.Demographics, stimulation parameters and embryological data were comparable in the two groups

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2011 Reproductive biology and endocrinology : RB&E

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