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41. New approaches to pharmacosurveillance for monitoring prescription frequency, diversity, and co-prescription in a large sentinel network of companion animal veterinary practices in the United Kingdom, 2014–2016 (PubMed)

; this raises important questions regarding the efficacy and safety of PAs prescribed to companion animals. This study explored new approaches for describing PA prescription, diversity and co-prescription in dogs, cats and rabbits utilising electronic health records (EHRs) from a sentinel network of 457 companion animal-treating veterinary sites throughout the UK over a 2-year period (2014-2016). A novel text mining-based identification and classification methodology was utilised to semi-automatically map (...) New approaches to pharmacosurveillance for monitoring prescription frequency, diversity, and co-prescription in a large sentinel network of companion animal veterinary practices in the United Kingdom, 2014–2016 Pharmaceutical agents (PAs) are commonly prescribed in companion animal practice in the United Kingdom. However, little is known about PA prescription on a population-level, particularly with respect to PAs authorised for human use alone prescribed via the veterinary cascade

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2018 Preventive veterinary medicine

42. Interstate data sharing of prescription drug monitoring programs and associated opioid prescriptions among patients with non-cancer chronic pain. (PubMed)

Interstate data sharing of prescription drug monitoring programs and associated opioid prescriptions among patients with non-cancer chronic pain. All fifty states have implemented prescription drug monitoring programs (PDMPs) to reduce misuse and diversion of controlled drugs. Interstate PDMP data sharing has been called for by clinical practitioners, but evidence to support the effectiveness of PDMP data sharing is lacking. This study examined whether PDMP interstate data sharing (...) with bordering states was associated with prescriptions of opioids. This was a cross-sectional study that included patients with non-cancer chronic pain from the 2014 National Ambulatory Medical Care Survey (weighted N = 66,198,751; unweighted N = 2846). Multinomial logistic regression was performed to examine the association between PDMP interstate data sharing status and patients' being prescribed opioids for pain treatment, controlling for covariates guided by the Eisenberg's model of physician decision

2018 Preventive Medicine

43. The use of electronic alerts in primary care computer systems to identify the over-prescription of short acting beta2-agonists in people with asthma: a systematic review

The use of electronic alerts in primary care computer systems to identify the over-prescription of short acting beta2-agonists in people with asthma: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation

2016 PROSPERO

44. Electronically delivered interventions to reduce antibiotic prescribing for respiratory infections in primary care: cluster RCT using electronic health records and cohort study. (PubMed)

Electronically delivered interventions to reduce antibiotic prescribing for respiratory infections in primary care: cluster RCT using electronic health records and cohort study. Unnecessary prescribing of antibiotics in primary care is contributing to the emergence of antimicrobial drug resistance.To develop and evaluate a multicomponent intervention for antimicrobial stewardship in primary care, and to evaluate the safety of reducing antibiotic prescribing for self-limiting respiratory (...) infections (RTIs).A multicomponent intervention, developed as part of this study, including a webinar, monthly reports of general practice-specific data for antibiotic prescribing and decision support tools to inform appropriate antibiotic prescribing.A parallel-group, cluster randomised controlled trial.The trial was conducted in 79 general practices in the UK Clinical Practice Research Datalink (CPRD).All registered patients were included.The primary outcome was the rate of antibiotic prescriptions

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2019 Health technology assessment (Winchester, England) Controlled trial quality: predicted high

45. Prescribing and Dispensing Policies to Address Harms Associated With Prescription Drug Abuse

-resistant prescription pads or electronic PDMPs. Some Canadian, US, and New Zealand jurisdictions have payer incentives for pharmacist activities that address suspected misuse and abuse, such as refusing to fill a prescription. Some jurisdictions also restrict patients to a limited number of pharmacies or prescribers for accessing opioids, stimulants, and benzodiazepines. Prescription Drug–Monitoring Programs Most Canadian jurisdictions have some form of PDMP, or have programs in development. 1 (...) Prescribing and Dispensing Policies to Address Harms Associated With Prescription Drug Abuse Prescribing and Dispensing Policies to Address Harms Associated With Prescription Drug Abuse | CADTH.ca Find the information you need Prescribing and Dispensing Policies to Address Harms Associated With Prescription Drug Abuse Prescribing and Dispensing Policies to Address Harms Associated With Prescription Drug Abuse Published on: October 28, 2015 Project Number: ES0291-000 Product Line: Research Type

2015 Canadian Agency for Drugs and Technologies in Health - Environmental Scanning

46. Short-Term Prescription Refills for Patients Receiving Chronic Drug Therapy

study only. It may not be copied, posted on a web site, redistributed by email or stored on an electronic system without the prior written permission of CADTH or applicable copyright owner. Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners’ own terms and conditions. TITLE: Short-Term Prescription Refills for Patients (...) Short-Term Prescription Refills for Patients Receiving Chronic Drug Therapy Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses should

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

47. Secure Prescription Pads for Prescribing of Medications Prone to Abuse and Misuse

study only. It may not be copied, posted on a web site, redistributed by email or stored on an electronic system without the prior written permission of CADTH or applicable copyright owner. Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners’ own terms and conditions. TITLE: Secure Prescription Pads for Prescribing (...) Secure Prescription Pads for Prescribing of Medications Prone to Abuse and Misuse Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses should

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

48. Risk factors for medication errors in the electronic and manual prescription (PubMed)

Risk factors for medication errors in the electronic and manual prescription to compare electronic and manual prescriptions of a public hospital of Brasilia, identifying risk factors for the occurrence of medication errors.descriptive-exploratory, comparative and retrospective study. Data collection occurred from July 2012 to January 2013, using an instrument for the review of the information contained in medical records related to the medication process. A total of 190 manual and 199 (...) electronic records composed the sample, with 2027 prescriptions each.compared to the manual prescription, a significant reduction was observed in the risk factors after implantation of the electronic prescription, in items such as "lack of the form of dilution" (71.1% to 22.3%) and "prescription with brand name" (99.5% to 31.5%). Conversely, the risk factors "no check" and "lack of CRM of the prescriber" increased. The lack of the allergy registration and the occurrences related to medication were

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2016 Revista latino-americana de enfermagem

49. Electronic Alerts with Automated Consultations Promote Appropriate Antimicrobial Prescriptions (PubMed)

Electronic Alerts with Automated Consultations Promote Appropriate Antimicrobial Prescriptions To promote appropriate antimicrobial use in bloodstream infections (BSIs), we initiated an intervention program consisting of electronic alerts and automated infectious diseases consultations in which the identification and antimicrobial susceptibility test (ID/AST) results were reported.We compared the appropriateness of antimicrobial prescriptions and clinical outcomes in BSIs before and after (...) at 24 hours after reporting, immediately after program initiation. No significant baseline trends or changes in trends were identified. There were no significant differences in time to intravenous to oral switch therapy, length of stay, and 30-day mortality rate.This novel form of stewardship program based on intervention by infectious disease specialists and information technology improved antimicrobial prescriptions in BSIs.

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2016 PloS one

50. Optimized Computerized Order Entry can Reduce Errors in Electronic Prescriptions and Associated Pharmacy Calls to Clarify (CTC) (PubMed)

Optimized Computerized Order Entry can Reduce Errors in Electronic Prescriptions and Associated Pharmacy Calls to Clarify (CTC) After implementation of a system-wide EMR within our university system, e-prescribing is now commonplace.The authors conducted a study to assess whether optimization of computerized provider order entry (CPOE) can reduce errors in these electronically transmitted prescriptions and would require less frequent interventions from pharmacists, in particular the need (...) for them to "call to clarify" (CTC) details of particular prescriptions. Secondary analysis based on cost assumptions was preformed to presume cost differences before and after optimization changes.In order to generate complete, error-free prescriptions, optimization changes were implemented in the form of in line validation messages. These messages were generated if (1) an order did not specify a provider or pharmacy; (2) the DEA requirements were not met; (3) character limits were exceeded in patient

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2016 Applied clinical informatics

51. Modelling and extraction of variability in free-text medication prescriptions from an anonymised primary care electronic medical record research database. (PubMed)

Modelling and extraction of variability in free-text medication prescriptions from an anonymised primary care electronic medical record research database. Free-text medication prescriptions contain detailed instruction information that is key when preparing drug data for analysis. The objective of this study was to develop a novel model and automated text-mining method to extract detailed structured medication information from free-text prescriptions and explore their variability (e.g. optional (...) dosages) in primary care research databases.We introduce a prescription model that provides minimum and maximum values for dose number, frequency and interval, allowing modelling variability and flexibility within a drug prescription. We developed a text mining system that relies on rules to extract such structured information from prescription free-text dosage instructions. The system was applied to medication prescriptions from an anonymised primary care electronic record database (Clinical Practice

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2016 Medical Informatics and Decision Making

52. CREATING AND AUDITING A NEW ELECTRONIC CONTINUOUS INFUSION PRESCRIPTION CHART FOR A PAEDIATRIC CRITICAL CARE UNIT. (PubMed)

CREATING AND AUDITING A NEW ELECTRONIC CONTINUOUS INFUSION PRESCRIPTION CHART FOR A PAEDIATRIC CRITICAL CARE UNIT. Prescription errors, including continuous infusion prescriptions are one major source of concern in the paediatric population. Evidence suggests that use of an electronic or web-based calculator could minimise these errors. In our paediatric critical care unit (PCCU) we have created an electronic continuous infusion prescription chart to target errors in this area and conducted (...) an audit to assess its effect on error reduction.To create an electronic continuous infusion prescription chart and audit its effect on prescription errors.Similar electronic continuous infusion prescription charts were evaluated. A Choice of electronic formats were considered and excel was chosen for its simplicity and flexibility. The choice of medications to be included, dilution method, and dosage range was agreed between PCCU consultant, pharmacy and nursing staff. Formulas for calculating each

2016 Archives of Disease in Childhood

53. IMPLEMENTATION OF AN ELECTRONIC PRESCRIPTION CHART FOR GENTAMICIN FOR NEONATAL UNITS AND POSTNATAL WARDS. (PubMed)

IMPLEMENTATION OF AN ELECTRONIC PRESCRIPTION CHART FOR GENTAMICIN FOR NEONATAL UNITS AND POSTNATAL WARDS. Since the introduction of NICE guidance for Early Onset Neonatal Sepsis (EONS)1 in August 2012, the number of locally reported prescribing and administration errors involving gentamicin has increased. This guideline introduced a new, unfamiliar regimen to staff working on the Neonatal Units and Postnatal wards. Analysis of the errors suggested 36 hourly frequency of gentamicin contributed (...) to the errors due to the complexities of prescribing on the paper drug chart. Our aim was to reduce errors involving gentamicin through the introduction of a Microsoft Excel® based electronic prescription chart.Local medication incident reports for gentamicin were analysed from 1st September 2013 to 3rd October 2014 (prior to the introduction of the new prescription chart). The new prescription chart was introduced from 5 January 2015. Incident reports continued to be monitored until 30th July 2015

2016 Archives of Disease in Childhood

54. AN ELECTRONIC PRESCRIPTION ALERTING SYSTEM-IMPROVING THE DISCHARGE MEDICINES PROCESS. (PubMed)

AN ELECTRONIC PRESCRIPTION ALERTING SYSTEM-IMPROVING THE DISCHARGE MEDICINES PROCESS. Whilst the prescribing of both in-patient and discharge medicines is electronic, there was no automatic notification to clinical pharmacists when a discharge prescription was ready to be screened. The notification required a member of medical or nursing staff to bleep their pharmacist informing them of a prescription's availability. This manual process led to a delay in pharmacist screening which impacted (...) the email body. The email is sent to named individuals within a given distribution list. The function is scalable to support all areas using Trust eDischarge Summaries.The system was introduced in April 2015. Data from before (June 2014-January 2015) and after (June 2015) implementation was compared.Prior to the introduction of an electronic alerting system the average time from a prescriber signing a prescription to clinical pharmacist screening was 93 minutes. Three months after starting the new

2016 Archives of Disease in Childhood

55. Evaluating the implementation of RxNorm in ambulatory electronic prescriptions. (PubMed)

Evaluating the implementation of RxNorm in ambulatory electronic prescriptions. RxNorm is a standardized drug nomenclature maintained by the National Library of Medicine that has been recommended as an alternative to the National Drug Code (NDC) terminology for use in electronic prescribing. The objective of this study was to evaluate the implementation of RxNorm in ambulatory care electronic prescriptions (e-prescriptions).We analyzed a random sample of 49 997 e-prescriptions that were (...) received by 7391 locations of a national retail pharmacy chain during a single day in April 2014. The e-prescriptions in the sample were generated by 37 801 ambulatory care prescribers using 519 different e-prescribing software applications.We found that 97.9% of e-prescriptions in the study sample could be accurately represented by an RxNorm identifier. However, RxNorm identifiers were actually used as drug identifiers in only 16 433 (33.0%) e-prescriptions. Another 431 (2.5%) e-prescriptions

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2015 Journal of the American Medical Informatics Association

56. The effects of introducing an electronic prescription system with no copayments (PubMed)

The effects of introducing an electronic prescription system with no copayments To examine the impact of introducing an electronic prescription system with no copayments on the number of prescriptions, the size of prescriptions, and the number of visits and phone calls to primary physicians.Fixed regression models using monthly data on per capita prescriptions claims and consultations between 2009 and 2013 at the municipality level, before and after the introduction of the electronic (...) prescription system.The electronic prescription system with no copayment increased the number of prescriptions by between 6.0 and 8.1 %. It decreased the average size of each prescription, but it did not decrease the number of consultations.The reduced direct and indirect costs of obtaining prescriptions after the introduction of the electronic prescription system changed the financial incentives facing the patients and physicians. This led to significant changes in the level and size of prescriptions

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2015 Health economics review

57. Electronic Prescription Data to Improve Primary Care Prescribing

Electronic Prescription Data to Improve Primary Care Prescribing Electronic Prescription Data to Improve Primary Care Prescribing - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Electronic Prescription Data (...) Research Official Title: Electronic Prescription Data to Improve Primary Care Prescribing Study Start Date : July 2015 Actual Primary Completion Date : January 2017 Actual Study Completion Date : July 1, 2017 Arms and Interventions Go to Arm Intervention/treatment Experimental: Bronchodilators Prescription Data Feedback to GP Practices - practices will be fed back data for people with presumed asthma who have either been dispensed more than 12 short-acting beta-agonist bronchodilators in the last 12

2015 Clinical Trials

58. Prescription Errors Before and After Introduction of Electronic Medication Alert System in a Pediatric Emergency Department. (PubMed)

Prescription Errors Before and After Introduction of Electronic Medication Alert System in a Pediatric Emergency Department. Prescription errors occur frequently in pediatric emergency departments (PEDs).The effect of computerized physician order entry (CPOE) with electronic medication alert system (EMAS) on these is unknown. The objective was to compare prescription errors rates before and after introduction of CPOE with EMAS in a PED. The hypothesis was that CPOE with EMAS would significantly (...) reduce the rate and severity of prescription errors in the PED.A prospective comparison of a sample of outpatient, medication prescriptions 5 months before and after CPOE with EMAS implementation (7,268 before and 7,292 after) was performed. Error types and rates, alert types and significance, and physician response were noted. Medication errors were deemed significant if there was a potential to cause life-threatening injury, failure of therapy, or an adverse drug effect.There was a significant

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2015 Academic Emergency Medicine

59. Meeting user needs in national healthcare systems: lessons from early adopter community pharmacists using the electronic prescriptions service. (PubMed)

Meeting user needs in national healthcare systems: lessons from early adopter community pharmacists using the electronic prescriptions service. The Electronic Prescription Service release Two (EPS2) is a new national healthcare information and communication technology in England that aims to deliver effective prescription writing, dispensing and reimbursement service to benefit patients. The aim of the study was to explore initial user experiences of Community Pharmacists (CPs) using EPS2.We (...) conducted nonparticipant observations and interviews in eight EPS2 early adopter community pharmacies classified as 'first-of-type' in midlands and northern regions in England. We interviewed eight pharmacists and two dispensers in addition to 56 hours recorded nonparticipant observations as field notes. Line-by-line coding and thematic analysis was conducted on the interview transcripts and field notes.CPs faced two types of challenge. The first was to do with missing electronic prescriptions

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2014 Medical Informatics and Decision Making

60. Evaluation of a mobile electronic assistant to aid in fluindione prescription: The INRPlus cluster randomized trial. (PubMed)

Evaluation of a mobile electronic assistant to aid in fluindione prescription: The INRPlus cluster randomized trial. Regular monitoring of the international normalized ratio (INR) is crucial for dose adjustment of vitamin K antagonists (VKA) to maximize time in therapeutic range (TTR). We compared the use of a mobile electronic assistant INRPlus which proposes patient-specific fluindione doses, to standard fluindione management in a cluster randomized controlled study.Twenty clusters of six (...) % of non-compliant patients and 67.1% of reference patients.In this trial, the use of the INRPlus electronic assistant resulted in a non-significant improvement in TTR that may be due to a higher than expected TTR in the control group.Copyright © 2014 Elsevier Ltd. All rights reserved.

2014 Thrombosis research Controlled trial quality: uncertain

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