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41. Interstate data sharing of prescription drug monitoring programs and associated opioid prescriptions among patients with non-cancer chronic pain. (PubMed)

Interstate data sharing of prescription drug monitoring programs and associated opioid prescriptions among patients with non-cancer chronic pain. All fifty states have implemented prescription drug monitoring programs (PDMPs) to reduce misuse and diversion of controlled drugs. Interstate PDMP data sharing has been called for by clinical practitioners, but evidence to support the effectiveness of PDMP data sharing is lacking. This study examined whether PDMP interstate data sharing (...) with bordering states was associated with prescriptions of opioids. This was a cross-sectional study that included patients with non-cancer chronic pain from the 2014 National Ambulatory Medical Care Survey (weighted N = 66,198,751; unweighted N = 2846). Multinomial logistic regression was performed to examine the association between PDMP interstate data sharing status and patients' being prescribed opioids for pain treatment, controlling for covariates guided by the Eisenberg's model of physician decision

2018 Preventive Medicine

42. CEO Statement: Electronic cigarettes (e-cigarettes)

CEO Statement: Electronic cigarettes (e-cigarettes) CEO Statement: Electronic cigarettes | NHMRC NHMRC Tagline NHMRC Tagline Publication date Publication date Content type Filtered by: All Publications News Page Search Quick links Toggle navigation Main navigation Funding One researcher has the potential to improve millions of lives. We provide funding for research through our grant system, with a transparent peer-review process to determine how funding is allocated. May 07 2018 May 07 2018 (...) and help them protect intellectual property. Jun 14 2018 Jul 25 2018 About us At NHMRC we are excited by the huge potential benefits of the research we fund and by the opportunities we have to ensure Australians have access to evidence-based, authoritative health advice. We create pathways to a healthier future through our research funding, our health guidelines and the ethical standards we set and uphold. Jul 25 2018 Jul 25 2018 CEO Statement: Electronic cigarettes CEO Statement: Electronic cigarettes

2018 National Health and Medical Research Council

43. Development of a Web-Based Clinical Decision Support System for Drug Prescription: Non-Interventional Naturalistic Description of the Antipsychotic Prescription Patterns in 4345 Outpatients and Future Applications. (PubMed)

Development of a Web-Based Clinical Decision Support System for Drug Prescription: Non-Interventional Naturalistic Description of the Antipsychotic Prescription Patterns in 4345 Outpatients and Future Applications. The emergence of electronic prescribing devices with clinical decision support systems (CDSS) is able to significantly improve management pharmacological treatments. We developed a web application available on smartphones in order to help clinicians monitor prescription and further (...) propose CDSS.A web application (www.MEmind.net) was developed to assess patients and collect data regarding gender, age, diagnosis and treatment. We analyzed antipsychotic prescriptions in 4345 patients attended in five Psychiatric Community Mental Health Centers from June 2014 to October 2014. The web-application reported average daily dose prescribed for antipsychotics, prescribed daily dose (PDD), and the PDD to defined daily dose (DDD) ratio.The MEmind web-application reported that antipsychotics

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2016 PLoS ONE

44. Prescribing and Dispensing Policies to Address Harms Associated With Prescription Drug Abuse

-resistant prescription pads or electronic PDMPs. Some Canadian, US, and New Zealand jurisdictions have payer incentives for pharmacist activities that address suspected misuse and abuse, such as refusing to fill a prescription. Some jurisdictions also restrict patients to a limited number of pharmacies or prescribers for accessing opioids, stimulants, and benzodiazepines. Prescription Drug–Monitoring Programs Most Canadian jurisdictions have some form of PDMP, or have programs in development. 1 (...) Prescribing and Dispensing Policies to Address Harms Associated With Prescription Drug Abuse Prescribing and Dispensing Policies to Address Harms Associated With Prescription Drug Abuse | CADTH.ca Find the information you need Prescribing and Dispensing Policies to Address Harms Associated With Prescription Drug Abuse Prescribing and Dispensing Policies to Address Harms Associated With Prescription Drug Abuse Published on: October 28, 2015 Project Number: ES0291-000 Product Line: Research Type

2015 Canadian Agency for Drugs and Technologies in Health - Environmental Scanning

45. Secure Prescription Pads for Prescribing of Medications Prone to Abuse and Misuse

study only. It may not be copied, posted on a web site, redistributed by email or stored on an electronic system without the prior written permission of CADTH or applicable copyright owner. Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners’ own terms and conditions. TITLE: Secure Prescription Pads for Prescribing (...) Secure Prescription Pads for Prescribing of Medications Prone to Abuse and Misuse Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses should

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

46. Short-Term Prescription Refills for Patients Receiving Chronic Drug Therapy

study only. It may not be copied, posted on a web site, redistributed by email or stored on an electronic system without the prior written permission of CADTH or applicable copyright owner. Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners’ own terms and conditions. TITLE: Short-Term Prescription Refills for Patients (...) Short-Term Prescription Refills for Patients Receiving Chronic Drug Therapy Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses should

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

47. Electronic prescribing: risk of potentially harmful errors

physician order entry, CPOE). Some of these errors are similar to those seen with handwritten prescriptions, while others are specific to electronic prescribing and arise through complex mechanisms. Software bugs, computer failure and unreliable or slow internet connections can lead to errors and data loss. The way information is displayed on the screen, often too dense, is also a source of errors. Inputting text outside a field subject to checks – which is often used to bypass a problem – runs the risk (...) Electronic prescribing: risk of potentially harmful errors Prescrire IN ENGLISH - Spotlight ''Electronic prescribing: risk of potentially harmful errors'', 1 July 2016 {1} {1} {1} | | > > > Electronic prescribing: risk of potentially harmful errors Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Electronic prescribing: risk of potentially harmful

2016 Prescrire

48. Prescription opioid use disorder and heroin use among youth nonmedical prescription opioid users from 2002 to 2014 (PubMed)

Prescription opioid use disorder and heroin use among youth nonmedical prescription opioid users from 2002 to 2014 27614657 2018 04 04 2018 11 13 1873-6327 65 2017 02 Addictive behaviors Addict Behav Prescription opioid use disorder and heroin use among 12-34 year-olds in the United States from 2002 to 2014. 236-241 S0306-4603(16)30314-8 10.1016/j.addbeh.2016.08.033 Martins Silvia S SS Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th St., New York (...) , NY 10032, USA. Electronic address: ssm2183@columbia.edu. Segura Luis E LE Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th St., New York, NY 10032, USA. Electronic address: les2196@cumc.columbia.edu. Santaella-Tenorio Julian J Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th St., New York, NY 10032, USA. Electronic address: js4222@cumc.columbia.edu. Perlmutter Alexander A Department of Epidemiology

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2016 Addictive behaviors

49. Continued Statin Prescriptions After Adverse Reactions and Patient Outcomes: A Cohort Study. (PubMed)

Continued Statin Prescriptions After Adverse Reactions and Patient Outcomes: A Cohort Study. Many patients discontinue statin treatment, often after having a possible adverse reaction. The risks and benefits of continued statin therapy after an adverse reaction are not known.To examine the relationship between continuation of statin therapy (any prescription within 12 months after an adverse reaction) and clinical outcomes.Retrospective cohort study.Primary care practices affiliated with 2 (...) academic medical centers.Patients with a presumed adverse reaction to a statin between 2000 and 2011.Information on adverse reactions to statins was obtained from structured electronic medical record data or natural-language processing of narrative provider notes. The primary composite outcome was time to a cardiovascular event (myocardial infarction or stroke) or death.Most (81%) of the adverse reactions to statins were identified from the text of electronic provider notes. Among 28 266 study patients

2017 Annals of Internal Medicine

50. Zolpidem in comatose patients: Prescriptions on clinical practice and time for a new randomized clinical trial. (PubMed)

Zolpidem in comatose patients: Prescriptions on clinical practice and time for a new randomized clinical trial. 30682515 2019 01 25 1878-8769 2019 Jan 22 World neurosurgery World Neurosurg Zolpidem in comatose patients: Prescriptions on clinical practice and time for a new randomized clinical trial. S1878-8750(19)30146-9 10.1016/j.wneu.2019.01.049 Welling Leonardo C LC Neurological Surgery Department. State University of Ponta Grossa. Brazil. Welling Mariana S MS Neurology Department. State (...) University of Ponta Grossa. Brazil. Figueiredo Eberval G EG Neurological Surgery Department. University of Sao Paulo. Brazil. Electronic address: ebgadelha@yahoo.com. eng Journal Article 2019 01 22 United States World Neurosurg 101528275 1878-8750 2019 1 26 6 0 2019 1 27 6 0 2019 1 27 6 0 aheadofprint 30682515 S1878-8750(19)30146-9 10.1016/j.wneu.2019.01.049

2019 World neurosurgery

51. Identifying Factors That Predict the Prescription of Non-vitamin K Antagonist Oral Anticoagulants in Older Individuals With Atrial Fibrillation. (PubMed)

Identifying Factors That Predict the Prescription of Non-vitamin K Antagonist Oral Anticoagulants in Older Individuals With Atrial Fibrillation. Factors that influence decision of non-vitamin K antagonist oral anticoagulants (NOACs) use among older atrial fibrillation (AF) patients in long-term care (LTC) facilities have not been well studied. The aim of this study was to assess whether increased frailty influenced physicians to prescribe NOACs over warfarin.We retrospectively reviewed (...) the electronic medical record (EMR) and pharmacy data of 25 LTC facilities in Ontario, Canada, in May 2015. The diagnosis of AF was ascertained from EMR and confirmed by complete chart review of a random sample of the cohort. A score of ≥2 on the Changes in Health, End-stage disease, Signs, and Symptoms (CHESS) scale was used as a surrogate marker of frailty.Multivariable logistic regression model was used to assess whether a higher frailty score is associated with the use of NOACs in comparison to warfarin

2019 Journal of the American Medical Directors Association

52. Long-term assessment of NSAID prescriptions and potential nephrotoxicity risk in adult kidney transplant recipients. (PubMed)

retrospectively followed in the VA system from 2001-10 that assessed for risk of AKI with NSAID prescriptions. NSAID prescriptions, patient characteristics and eGFRs were abstracted from the VA comprehensive electronic health record. NSAID exposure was assessed by duration, dosage and type. AKI events were defined by ≥50% decrease in eGFR. Risk was estimated using longitudinal multivariable generalized logistic regression model.5,100 patients were included with a total of 29,980 years of follow up; 671 NSAID (...) Long-term assessment of NSAID prescriptions and potential nephrotoxicity risk in adult kidney transplant recipients. NSAID use is recommended to be avoided in kidney transplantation (KTX), with a paucity of studies assessing their safety within this population. This study aims to use a large cohort of Veterans Affairs (VA) KTX recipients to assess the risk of acute kidney injury (AKI) with NSAID use.This is a ten-year longitudinal cohort study of adult kidney transplant recipients

2019 Transplantation

53. Intervention to reduce benzodiazepine prescriptions in primary care, study protocol of a hybrid type 1 cluster randomised controlled trial: the BENZORED study. (PubMed)

prescription and BZD deprescribing, monthly feedback about their BZD prescribing practices and access to a support web page. Outcome measures for each GP are the defined daily dosage per 1000 inhabitants per day and the proportion of long-term BZD users at 12 months. Data will be collected from the electronic prescription database of the public health system, and will be subjected to intention-to-treat analysis. Implementation will be evaluated by mixed methods following the five domains (...) Intervention to reduce benzodiazepine prescriptions in primary care, study protocol of a hybrid type 1 cluster randomised controlled trial: the BENZORED study. Benzodiazepines (BZDs) are mainly used to treat anxiety and sleep disorders, and are often prescribed for long durations, even though prescription guidelines recommend short-term use due to the risk of dependence, cognitive impairment, and falls and fractures. Education of general practitioners (GPs) regarding the prescription of BZDs

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2019 BMJ open

54. Examining the effect of prescription sequence on developing adverse drug reactions: The case of renal failure in diabetic patients. (PubMed)

emergent sequential pattern mining techniques to electronic health records.Using longitudinal medication and diagnosis records from more than 377,000 diabetic patients, in this study, we assessed the possible effect of prescription sequences in developing acute renal failure as a prevalent ADR among this group of patients. Relying on emergent sequential pattern mining, two statistical case-control approaches were designed and employed for this purpose.The results taken from the two employed approaches (...) Examining the effect of prescription sequence on developing adverse drug reactions: The case of renal failure in diabetic patients. While the effect of medications in development of Adverse Drug Reactions (ADRs) have been widely studied in the past, the literature lacks sufficient coverage in investigating whether the sequence in which [ADR-prone] drugs are prescribed (and administered) can increase the chances of ADR development. The present study investigates this potential effect by applying

2019 International journal of medical informatics

55. Evaluating the implementation of RxNorm in ambulatory electronic prescriptions. (PubMed)

Evaluating the implementation of RxNorm in ambulatory electronic prescriptions. RxNorm is a standardized drug nomenclature maintained by the National Library of Medicine that has been recommended as an alternative to the National Drug Code (NDC) terminology for use in electronic prescribing. The objective of this study was to evaluate the implementation of RxNorm in ambulatory care electronic prescriptions (e-prescriptions).We analyzed a random sample of 49 997 e-prescriptions that were (...) received by 7391 locations of a national retail pharmacy chain during a single day in April 2014. The e-prescriptions in the sample were generated by 37 801 ambulatory care prescribers using 519 different e-prescribing software applications.We found that 97.9% of e-prescriptions in the study sample could be accurately represented by an RxNorm identifier. However, RxNorm identifiers were actually used as drug identifiers in only 16 433 (33.0%) e-prescriptions. Another 431 (2.5%) e-prescriptions

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2015 Journal of the American Medical Informatics Association

56. Electronic Prescription Data to Improve Primary Care Prescribing

Electronic Prescription Data to Improve Primary Care Prescribing Electronic Prescription Data to Improve Primary Care Prescribing - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Electronic Prescription Data (...) Research Official Title: Electronic Prescription Data to Improve Primary Care Prescribing Study Start Date : July 2015 Actual Primary Completion Date : January 2017 Actual Study Completion Date : July 1, 2017 Arms and Interventions Go to Arm Intervention/treatment Experimental: Bronchodilators Prescription Data Feedback to GP Practices - practices will be fed back data for people with presumed asthma who have either been dispensed more than 12 short-acting beta-agonist bronchodilators in the last 12

2015 Clinical Trials

57. The effects of introducing an electronic prescription system with no copayments (PubMed)

The effects of introducing an electronic prescription system with no copayments To examine the impact of introducing an electronic prescription system with no copayments on the number of prescriptions, the size of prescriptions, and the number of visits and phone calls to primary physicians.Fixed regression models using monthly data on per capita prescriptions claims and consultations between 2009 and 2013 at the municipality level, before and after the introduction of the electronic (...) prescription system.The electronic prescription system with no copayment increased the number of prescriptions by between 6.0 and 8.1 %. It decreased the average size of each prescription, but it did not decrease the number of consultations.The reduced direct and indirect costs of obtaining prescriptions after the introduction of the electronic prescription system changed the financial incentives facing the patients and physicians. This led to significant changes in the level and size of prescriptions

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2015 Health economics review

58. Prescription Errors Before and After Introduction of Electronic Medication Alert System in a Pediatric Emergency Department. (PubMed)

Prescription Errors Before and After Introduction of Electronic Medication Alert System in a Pediatric Emergency Department. Prescription errors occur frequently in pediatric emergency departments (PEDs).The effect of computerized physician order entry (CPOE) with electronic medication alert system (EMAS) on these is unknown. The objective was to compare prescription errors rates before and after introduction of CPOE with EMAS in a PED. The hypothesis was that CPOE with EMAS would significantly (...) reduce the rate and severity of prescription errors in the PED.A prospective comparison of a sample of outpatient, medication prescriptions 5 months before and after CPOE with EMAS implementation (7,268 before and 7,292 after) was performed. Error types and rates, alert types and significance, and physician response were noted. Medication errors were deemed significant if there was a potential to cause life-threatening injury, failure of therapy, or an adverse drug effect.There was a significant

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2015 Academic Emergency Medicine

59. Effectiveness and safety of electronically delivered prescribing feedback and decision support on antibiotic use for respiratory illness in primary care: REDUCE cluster randomised trial. (PubMed)

electronically, supported by a local practice champion nominated for the trial.Primary outcome was the rate of antibiotic prescriptions for respiratory tract infections from electronic health records. Serious bacterial complications were evaluated for safety. Analysis was by Poisson regression with general practice as a random effect, adjusting for covariates. Prespecified subgroup analyses by age group were reported.The trial included 41 AMS practices (323 155 patient years) and 38 usual care practices (259 (...) Effectiveness and safety of electronically delivered prescribing feedback and decision support on antibiotic use for respiratory illness in primary care: REDUCE cluster randomised trial. To evaluate the effectiveness and safety at population scale of electronically delivered prescribing feedback and decision support interventions at reducing antibiotic prescribing for self limiting respiratory tract infections.Open label, two arm, cluster randomised controlled trial.UK general practices

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2019 BMJ

60. Merging Electronic Health Record Data and Genomics for Cardiovascular Research

available in the EHR) and in the posttest state (a high-risk genetic test result is already in the EHR). In the future, interoperability of EHRs could allow genetic test results to be available at all relevant points of care, including dispensing pharmacies and outpatient clinics ( ). Figure. Current and future approaches to filling prescriptions. Genetic test results obtained from electronic health records (EHRs) could guide diagnosis and suggest drug dosages. Preemptive testing has the advantage (...) Merging Electronic Health Record Data and Genomics for Cardiovascular Research Merging Electronic Health Record Data and Genomics for Cardiovascular Research | Circulation: Cardiovascular Genetics Search Hello Guest! Login to your account Email Password Keep me logged in Search February 2019 January 2019 This site uses cookies. By continuing to browse this site you are agreeing to our use of cookies. Free Access article Share on Jump to Free Access article Merging Electronic Health Record Data

2016 American Heart Association

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