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4161. Breathing Exercises in Asthma Targeting Dysfunctional Breathing

the number of days during the last seven days the participant took his/her asthma medication as prescribed. The participant is interviewed at the inhalationcheck, and will answer 0 to 7 referring to the number of days. Assessed again at 6 months follow up by questionnaire. Adherence to physiotherapy-sessions [ Time Frame: At 12 months follow-up. ] Adherence to the physiotherapist-sessions during the 12 weeks intervention will be investigated though data extracted in the electronically medical records (...) months before baseline until 12 months follow-up. ] Comorbidity (types and numbers) and number of consultations at nurse and/or pulmonologist. Register of Medical Product Statistics [ Time Frame: 12 months before baseline until 12 months follow-up. ] For precise measure extraction of prescriptions on anti-asthmatic medication and comorbid medication on ATC-codes. Foster Score [ Time Frame: Change from inhalationcheck (before baseline) to 6 months follow up. ] Foster Score is used to investigate

2017 Clinical Trials

4162. Metastatic Breast Cancer Treatment Planning

Masking: None (Open Label) Primary Purpose: Supportive Care Official Title: Impact of Electronic Treatment Plans on Shared Decision Making for Metastatic Breast Cancer: An Educational/Research Initiative Estimated Study Start Date : July 1, 2017 Actual Primary Completion Date : January 31, 2018 Actual Study Completion Date : January 31, 2018 Resource links provided by the National Library of Medicine related topics: related topics: Arms and Interventions Go to Intervention Details: Other: Carevive CPS (...) This intervention will focus on the use of the Carevive CPS at the point of treatment decision making, enabling providers to deliver evidence-based and personalized treatment care plans to their metastatic breast cancer patients on active treatment. The Carevive CPS collects electronic patient reported outcomes (ePROs) and clinical data, reported and generated by clinical staff and/or peer-reviewed evidence, and includes patient education, resources, and referrals developed by cancer clinicians and researchers

2017 Clinical Trials

4163. Real World Data on Management of Male LUTS

Time Perspective: Retrospective Official Title: Real World Data Exploring the Practices of Primary Care Providers in the Managment of Male Lower Urinary Tract Symptoms Study Start Date : May 2016 Actual Primary Completion Date : December 2016 Actual Study Completion Date : December 2016 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Outcome Measures Go to Primary Outcome Measures : The percentage of men given a drug prescription (...) to the date of the phone interview. Able to read, speak and understand English. Willing to provide informed consent for study participation, authorize the release of their previous 12-month medical records from their PCP for review and de-identified data entry by Mapi into an electronic study database. Exclusion criteria: Reported during screening that they had had their first-ever discussion of urinary symptoms with PCP within the 14 days prior to the date of the phone interview. Participation

2017 Clinical Trials

4164. Femoroacetabular Impingement (FAI): The Effectiveness of Physical Therapy

in the avoidance of surgical intervention. The investigators plan to evaluate this using an electronic outcomes data collection system. The hypothesis is that the majority of patients will not see a significant enough improvement with physical therapy to avoid surgery, especially in a subset of patients such as those with sub spine impingement. The investigators plan to prospectively collect data for three years and monitor the outcome of each hip patient, especially those treated with physical therapy (...) Completion Date : February 2019 Resource links provided by the National Library of Medicine related topics: Groups and Cohorts Go to Group/Cohort Femoracetabular impingent (FAI) Subjects will be given a prescription for physical therapy specifically for Femoracetabular impingent (FAI). They will then be followed clinically per the investigator's normal routine and the gold standard. Outcome Measures Go to Primary Outcome Measures : Change in sub spine impingement associated with physical therapy [ Time

2017 Clinical Trials

4165. Transplant Regimen Adherence for Kidney Recipients by Engaging Information Technologies: The TAKE IT Trial

includes: Programming the electronic health record (EHR) to organize/simplify daily regimen schedules and generate electronic, tangible, print, low literacy medication education materials at every clinical encounter. SMS text-messaging to remind patients when to take all their medicine. A web-based patient portal that requests patients to periodically report upon their medication use, providing a continuous link between the transplant center and patient beyond routine in-person visits. EHR (...) notifications directed to the transplant center nurse coordinator if an adherence-related problem is identified by the web-based portal assessment, who then can activate appropriate staff to respond. Outcome Measures Go to Primary Outcome Measures : Rx in-person pill count [ Time Frame: 2 years ] An in-person pill count using established guidelines will be conducted. Adherence will be assessed within drugs. The proportion of pills taken/pills prescribed will be calculated per medication. Patients

2017 Clinical Trials

4166. Patient-reported Monitoring of Symptoms and Spirometry Via the patientMpower Platform in Idiopathic Pulmonary Fibrosis

Posted : April 7, 2017 Results First Posted : January 23, 2019 Last Update Posted : January 23, 2019 Sponsor: patientMpower Ltd. Collaborator: Health Service Executive, Ireland Information provided by (Responsible Party): patientMpower Ltd. Study Details Study Description Go to Brief Summary: Pilot-scale, open-label, fixed-order, two-period crossover study in idiopathic pulmonary fibrosis (IPF) over 16 weeks. Patients will use an electronic health journal (patientMpower platform) to record treatment (...) ; Period 2: usual care alone for 8 weeks Other: patientMpower platform electronic health journal for patient to record compliance, spirometry, impact on daily life and symptoms Other: usual care usual care Outcome Measures Go to Primary Outcome Measures : Acceptability of patientMpower Platform From Patient & Healthcare Professional Perspective [ Time Frame: single measurement at 8 weeks ] Questionnaire-based assessment of response to questions: [pMp = patientMpower platform] instructions for using pMp

2017 Clinical Trials

4167. Pharmacist-led Intervention on Adherence in Patients Undergoing Treatment With an Oral Oncology Medication

consultation, patients will be administered the PAM 13 survey. Patients with a treatment gap >37 days will be referred to the consulting pharmacist for follow up. The consulting pharmacist will attempt to contact the patient via telephone for an assessment of adherence and adverse drug-related events. If patients experience a treatment gap >45, then the patient will be contacted and scheduled for a pharmacist consultation, additionally, the prescribing provider will be notified. All consultations (...) and interventions will be documented in the hospital's electronic medical record system, EPIC®. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 72 participants Allocation: Non-Randomized Intervention Model: Parallel Assignment Intervention Model Description: Pharmacist-led intervention group vs historical-control group Masking: None (Open Label) Primary Purpose: Health Services Research Official Title: Evaluating Adherence and Persistence

2017 Clinical Trials

4168. A Clinical Trial of Water Therapy for Autosomal Dominant Polycystic Kidney Disease

intake based on the principal investigator's prescription. The actual amount of extra water prescribed will depend on the results of the participant's 24 hour urine test. Outcome Measures Go to Primary Outcome Measures : Change in total kidney volume, as measured from magnetic resonance imaging [ Time Frame: 18 months ] Total kidney volumes will be measured before and after the period of high water intake. Kidney volume growth with high water intake will be compared to baseline kidney volume growth (...) of Medicine related topics: related topics: Arms and Interventions Go to Arm Intervention/treatment No Intervention: Usual Water Intake For the first 6 months of the study, the participants will continue their usual water intake. Experimental: High Water Intake After a 6 month period of usual water intake, a high water intake daily amount will be prescribed for 1 year. Other: High Water Intake After 6 months of usual, unchanged diet and fluid intake, participants will be asked to increase the daily fluid

2017 Clinical Trials

4169. Pepped on Pre-exposure Prophylaxis (PrEP): A Counseling and Problem-Solving PrEP Adherence Intervention for Stimulant Using Men Who Have Sex With Men (MSM).

prescribed PrEP through the Miriam Hospital, the study participants will be randomly assigned to one of two treatment conditions. In the intervention condition, participants will receive a two-stepped intervention which could include up to 10 free BA and risk reduction (RR) counseling sessions. Participants assigned to the comparison condition will receive the standard of care for PrEP treatment at the Miriam Hospital, which includes information about PrEP and how to obtain it, assistance from medical (...) as associated factors, including depression, as barriers to optimal PrEP adherence. No Intervention: Standard of Care PrEP adherence counseling from the Miriam Hospital PrEP Clinic. Outcome Measures Go to Primary Outcome Measures : PrEP Uptake [ Time Frame: Baseline Stage 2 ] >80% of participants who complete Stage 1 baseline and report PrEP initiation (verified by prescription) will progress to Stage 2 Baseline. Improve rate of PrEP adherence [ Time Frame: Daily beginning at Stage 2 Baseline up to the four

2017 Clinical Trials

4170. Medication Usage and Patient Reported Outcomes Evaluation Via myBETAapp in Patients With Multiple Sclerosis Treated With Betaferon: a Pilot Study

Betaferon box contains a "Mixject" number, which is a product specific number unrelated to the study. Only patients prescribed Betaferon for their MS will be able to use the myBETAapp and participate in the study). Patients must be using the myBETAapp. Electronic informed consent must be obtained. Exclusion Criteria: -There are no exclusion criteria for participation in this study. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your

2017 Clinical Trials

4171. The Life STORRIED Study

): University of Pennsylvania Study Details Study Description Go to Brief Summary: To compare the effectiveness of 3 strategies to inform patients of their risks associated with misuse of opioid prescriptions after treatment in the ED from renal colic or musculoskeletal back pain. Randomization will be to 3 arms for the Randomized Practical Control Trial across 3 sites (A) standardized general risk information sheet only (B) standardized general risk information sheet plus a visual probabilistic risk tool (...) (C) standardized sheet plus narrative enhanced probabilistic risk tool. Condition or disease Intervention/treatment Phase Opioid Dependence Communication Risk Behavior Narrative Medicine Other: Probabilistic Risk Communication Tool (PRT) Other: Narrative Enhanced Risk Tool (NERT) Not Applicable Detailed Description: Amid a devastating public health crisis, in which 19,000 overdose deaths per year in the United States are due to prescription opioids, the investigators ask the following questions

2017 Clinical Trials

4172. Provider Training in Increasing Patient Tobacco Cessation Counseling and Referrals for Patients With Cancer Undergoing Radiation Therapy

/community tobacco cessation resources for patients ready to quit within six weeks, and have access to pharmacy residents for ad-hoc prescribing questions. PATIENT COACHING: Patients attend 4 phone or in-person motivational interviewing coaching sessions over 30-45 minutes for 6-8 weeks or longer as needed. Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 400 participants Intervention Model: Single Group Assignment Masking: None (...) interviewing techniques. Providers also undergo training to use public/community tobacco cessation resources for patients ready to quit within six weeks, and have access to pharmacy residents for ad-hoc prescribing questions. PATIENT COACHING: Patients attend 4 phone or in-person motivational interviewing coaching sessions over 30-45 minutes for 6-8 weeks or longer as needed. Other: Communication Skills Training Undergo motivational interviewing training Other: Medical Chart Review Undergo medical chart

2017 Clinical Trials

4173. Occlusal Reduction and Postoperative Pain

to be administrated in case of severe pain and ibuprofen 400mg was prescribed in case of persistent pain. Condition or disease Intervention/treatment Phase Postoperative Pain Other: occlusal reduction Not Applicable Detailed Description: Recruitment of the study participants was done from the outpatient clinic of the Endodontic Department of the Faculty of Oral and Dental Medicine, Cairo University. Randomization was done to assign participants to the study groups by chance and not choice. 44 numbers were (...) steel hand K-files size #10 and #15. Working length was determined using an electronic apex locator and confirmed radiographically to be 1 mm shorter than radiographic apex. Mechanical preparation was done by crown-down technique using rotary Revo-S instruments and Ethylene Diamine Tetra Aceticacid gel as a lubricant. The canals were thoroughly irrigated using 3ml of 2.5% sodium hypochlorite following each instrument. After dryness of the canals using paper points, a cotton pellet was placed

2017 Clinical Trials

4174. Implementing a Paced Deep Breathing Module to Decrease Preoperative Anxiety in Gynecological Surgery Patients

to reduce anxiety also result in improved post-operative behavioral and clinical recovery. Currently, the most common method to treat preoperative anxiety is the administration of a prescription benzodiazepine. However, there is limited clinical evidence that supports the use of sedative premedication, such as with a benzodiazepine, before surgery. Complementary integrative medical therapies including music, massage, guided imagery, and deep breathing have been proposed to minimize stress and pain (...) Experimental: meditation module The patients in this arm will be offered the meditation/deep breathing module in the pre-operative area. Device: iPad a 10 minute electronic guided deep breathing module offered via an iPad Outcome Measures Go to Primary Outcome Measures : change in anxiety [ Time Frame: recorded immediately pre-intervention and immediately post-intervention (once meditation module is complete) ] rated 0-10 on a numeric rating scale Secondary Outcome Measures : patient satisfaction [ Time

2017 Clinical Trials

4175. Nurse-led Medicines' Monitoring in Care Homes: a Process Evaluation

electronic devices can enhance nurse-led monitoring. Condition or disease Intervention/treatment Dementia Behavioral: West Wales Adverse Drug Reaction (WWADR) Profile Behavioral: usual care Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 30 participants Observational Model: Case-Only Time Perspective: Prospective Official Title: Nurse-led Medicines' Monitoring in Care Homes: a Process Evaluation of the Impact and Sustainability of the West Wales (...) to correct the problem, for example by prescription changes Clinical gain (anticipated and actual) Change needed to address problems identified Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general

2017 Clinical Trials

4176. Improving the Recovery and Outcome Every Day After the ICU

expectancy Current chemotherapy or radiation therapy (confirmed by electronic medical record) History of dementing illnesses and other neurodegenerative disease such as Alzheimer's disease, Parkinson disease, or vascular dementia (confirmed by EMR), or current prescription of anti-dementia medication, or ruled out by Functional Activities Questionnaire (FAQ) score defining dementia History of bipolar disorder or schizophrenia (confirmed by EMR) Current alcohol consumption > 5 drinks per day (self

2017 Clinical Trials

4177. Sub-optimal Response to Anti-Tumor Necrosis Factor's in Inflammatory Bowel Disease in Emerging Markets

in this retrospective study. The study will look to identify the local barriers in prescribing anti-TNF therapy, treatment patterns and indicators of sub-optimal response to anti-TNF therapy in UC and CD participants in real-world clinical practice in the EM countries, along with the associated incidence of sub-optimal response and impact on health care resource utilization (HCRU). The will enroll approximately 2000 participants. The study consists of two periods, eligibility period followed by a data abstraction (...) . This multi-center trial will be conducted in Argentina, China, Colombia, Mexico, Russia, Saudi Arabia, Singapore, South Korea, Taiwan and Turkey. The overall time to abstract data during the data extraction period from the web-based electronic data capture (EDC) system will be approximately 1 year from March 2017 to February 2018. Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 1731 participants Observational Model: Cohort Time Perspective

2017 Clinical Trials

4178. PREemptive Pharmacogenomic Testing for Preventing Adverse Drug REactions

or with standard of care in the first block. In the pharmacogenomics guided prescribing arm, results of the pharmacogenomic test will be incorporated in the (electronic) medical record and may be used by physicians and pharmacists to guide drug and dose selection for 42 routinely prescribed drugs, as per the Dutch Pharmacogenomics Working Group guidelines. In the standard of care arm, patients will not receive pharmacogenomic testing. After this 18-month block, the countries switch to implementing the opposite (...) : 18 Years and older (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Subject must be ≥ 18 years old Subject must receive a first prescription (meaning no known prescription for this drug in the preceding 12 months) for one or more of 42 drugs, for which a Dutch Pharmacogenomic Working Group guideline is available, which is prescribed to them in routine care Subject is able and willing to take part and be followed-up for at least 12

2017 Clinical Trials

4179. Impact of a Pharmaceutical Care Model in the Management of Chronic Myeloid Leukemia Patients

of the study period) from electronic prescription refill database system, which was further verified by patient self-reported of having a score of greater than or equal to 6 on Malaysian Medication Adherence Scale Secondary Outcome Measures : Changes in percentage of patients who achieve major/deep molecular response to TKI [ Time Frame: Evaluated at 2 time frame, (a) 0-3 months pre-intervention until 6 months after starting intervention; (b) 0-3 months pre-intervention until 6 months after the end (...) -long treatment remains the current standard of care. It has been estimated that 3% to 56% of CML patients are not adherent to their prescribed TKI therapy. Poor adherence to TKIs could compromise the control of CML, and contributes to poorer survival. CML patients on long-term TKI therapy are prone to developing certain medication-related issues such as adverse reactions and drug interactions.Occurrence of adverse reactions even at low grades, has been shown to impact CML patient's health-related

2017 Clinical Trials

4180. Insulin Degludec Titration Using Mobile Insulin Dosing System

dosing system(MIDS), using the STEP WISE degludec titration algorithm. The eligible subjects will be started on insulin degludec (Tresiba® U-200 FlexTouch®). Subjects will use MIDS for insulin degludec titration management. The clinician will configure MIDS Prescription Instruction Form(PIF) using pre-configured Novo Nordisk, Tresiba Protocol Dosing Treatment Plan which is based on the Novo Tresiba degludec Stepwise Program. The Clinician can alter this as appropriate based on medical judgment (...) a Glooko compatible smart device, a loaner smart device can be provided for the study period. Subject is currently performing self-monitoring of blood glucose(SMBG) Exclusion Criteria: Subject has had a severe hypoglycemia episode in the last 90 days Subject has type 1 diabetes Subject does not have access to a Glooko compatible smart device (smartphone or tablet) Subject must not be using Glooko or any other electronic application for insulin titration Subject is unable to read and understand English

2017 Clinical Trials

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