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Electronic Prescription

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4101. Lifestyle Education for Activity and Nutrition for a Leaner You

of Electronic Feedback on Diet and Physical Activity to Enhance Weight Management Study Start Date : February 2008 Actual Primary Completion Date : December 2009 Actual Study Completion Date : December 2009 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Experimental: A - GWL Group Weight Loss Program (GWL) - Participants in this group attended a 14-session group weight loss program administered by trained facilitators plus (...) with herbal, over-the-counter, or prescription weight loss drugs Current treatment with ant-metabolite medications or other medications that affect weight Current pregnancy or breastfeeding, or plans pregnancy in next 18 months gastrointestinal disorders including ulcerative colitis, Crohn's disease, malabsorption syndromes) Chronic renal insufficiency Chronic liver disease History of anorexia nervosa, bulimia, laxative abuse Current alcohol or substance abuse Chronic heart failure, New York Heart

2009 Clinical Trials

4102. Twice Daily Versus Once Daily Administration of the Tacrolimus in Lung Transplantation

and often leads to re-transplantation or death. Preventative procedures for improving the compliance are simplification of the dose of the immunosuppressants (a once daily dose instead of a twice daily dose), the prescription of an immunosuppressants with less side-effects and to raise the patient´s awareness for having the greatest responsibility for the efficacy of his therapy. Prospective studies and metaanalysis revealed that the probability for a good compliance can be more than doubled at once (...) variability and medication abstraction from the electronic devices) Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 25 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Prevention Official Title: Prospective Randomized Trial to Compare a Twice Daily to a Once Daily Administration of the Tacrolimus in Lung Transplanted Patients Study Start Date : July 2009 Actual

2009 Clinical Trials

4103. Prometra's Utilization in Mitigating Pain II

agrees to obtain pain medication prescriptions only from the investigator. Patient has provided written informed consent to participate in the study. Patient is considered by the investigator to be a medically and psychologically appropriate candidate for pump implantation. Investigator and/or study coordinator considers the patient to be able and willing to fulfill all study requirements. Exclusion Criteria: Patient has existing damage to the spinal column observed via MRI of spine (...) . Patient has a major coexisting medical condition (such as gastrointestinal problems, respiratory reserve / lung function problems, or heart conditions that cannot tolerate further lowering of blood pressure) that, in the opinion of the investigator, contraindicates an implantable pump. Patient will require MRI evaluation post-implantation. Patient has other implanted cardiac electronic devices. Patient has an occupation where he/she would be exposed to high current industrial equipment, powerful

2009 Clinical Trials

4104. Dementia Early Recognition and Response in Primary Care

randomly allocated will be given a summary of the NICE/SCIE dementia guidelines (2006) and offered workshop training and software at the end of the study. Experimental: Training Practices randomly allocated to the intervention arm will be asked to participate in tailored learning activities on dementia, over a three-month period and will be given an electronic training manual (based on Microsoft packages) which they can run in the background during and after consultations with people with known (...) or suspected dementia syndrome and face-to- face individualised workshop sessions. Other: Educational Dementia training Tailored learning activities on dementia, over a three-month period and will be given an electronic training manual (based on Microsoft packages) which they can run in the background during and after consultations with people with known or suspected dementia syndrome and face-to- face individualised workshop sessions. Tailoring of the education programme is carried out in a three step

2009 Clinical Trials

4105. Patient Portal to Support Treatment Adherence

of this study is to conduct a randomized control trial of a behavioral intervention delivered by nurses via an electronic medical record (EMR) patient web portal to determine if this is an efficacious method for supporting medication adherence. Condition or disease Intervention/treatment Phase Antiretroviral Medication Adherence Other: attention control Behavioral: adherence intervention Not Applicable Detailed Description: 300 adult HIV+ patients will be randomized to one of two arms. 150 will be assigned (...) to receive secure messages focused on antiretroviral adherence from a nurse through the health plan EMR patient website. 150 will be assigned to an attention control comparison arm, and will receive electronic messages from a study staff member that provide information about the various features of the health plan patient website. Patients will be invited by mail to be telephone screened for enrollment in the study. Patients will be provided the opportunity to opt out of being contacted by the study

2009 Clinical Trials

4106. Reducing gastric secretions--a role for histamine 2 antagonists or proton pump inhibitors in malignant bowel obstruction? (PubMed)

Reducing gastric secretions--a role for histamine 2 antagonists or proton pump inhibitors in malignant bowel obstruction? Inoperable bowel obstructions are not uncommon in advanced cancer and are associated with a very poor prognosis. Symptom control includes reducing the frequency of vomiting by prescription of antisecretory medications. The most commonly used agents for this are either hyoscine butylbromide or octreotide. Either histamine 2 antagonists or proton pump inhibitors are sometimes (...) recommended as adjuvants to reduce gastric secretions. The aim of this study was to examine the effects of histamine 2 antagonists and proton pump inhibitors and to objectively compare the effects of one agent over another.Previously, electronic databases were searched for trials that compared ranitidine versus proton pump inhibitors in their effect on volume of gastric aspirates.Seven trials were included in a meta-analysis. Pooled outcomes suggest that both proton pump inhibitors and ranitidine reduce

2009 Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

4107. The causes of and factors associated with prescribing errors in hospital inpatients: a systematic review. (PubMed)

and non-specialist hospitals, collate it, analyse it qualitatively and synthesize conclusions from it. Seven electronic databases were searched for articles published between 1985-July 2008. The reference lists of all informative studies were searched for additional citations. To be included, a study had to be of handwritten prescriptions for adult or child inpatients that reported empirically collected data on the causes of or factors associated with errors. Publications in languages other than

2009 Drug safety : an international journal of medical toxicology and drug experience

4108. General medications utilization and cost patterns in hospitalized children (PubMed)

pediatric admission units in a tertiary care university hospital.The total number of admitted children was 1,521 and 1,467 for the A and B admission units, respectively. The electronic data from 252 and 253 hospitalized children in the A and B admission unit were prospectively screened for general medication prescriptions, children on antimicrobials were excluded from the analysis. Their electronic charts were viewed once weekly from October 15, 2007 up to April 7, 2008 using the prescription-point (...) General medications utilization and cost patterns in hospitalized children Drug utilization in the in-patient setting can provide mechanisms to assess drug prescribing trends, efficiency and cost-effectiveness of hospital formularies and examine sub-populations such as children for which prescribing habits are different from adults.The aim of this descriptive study was to analyze general medication utilization patterns and costs excluding antimicrobials prescriptions and to compare two

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2009 Pharmacy Practice

4109. Can de facto Dosing Practices Bridge the Knowledge Gap in Pediatric Medication Recommendations? (PubMed)

Can de facto Dosing Practices Bridge the Knowledge Gap in Pediatric Medication Recommendations? A knowledge gap exists in pediatric medication dosing recommendations due in part to the complexity of researching medication efficacy and safety in children. One possible resource resides in the electronic prescribing practices of pediatric clinicians. In this study, de facto pediatric weight-based levothyroxine dosing practices were studied as a potential source for pediatric medication clinical (...) decision support. This was accomplished by extracting physical exam and prescription details from a well-used clinical data warehouse to calculate weight-based dosing practices, and comparing the results with established medication recommendations. Of the 854 prescriptions, 85.2% were under the recommended range, 9.37% were within the range and 5.39% were over the range. Thus, real world prescribing practices may differ from recommendations. Such information may be a valuable resource in pediatric

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2009 AMIA Annual Symposium Proceedings

4110. Assessment of ePrescription quality: an observational study at three mail-order pharmacies. (PubMed)

Assessment of ePrescription quality: an observational study at three mail-order pharmacies. The introduction of electronic transfer of prescriptions (ETP) or ePrescriptions in ambulatory health care has been suggested to have a positive impact on the prescribing and dispensing processes. Thereby, implying that ePrescribing can improve safety, quality, efficiency, and cost-effectiveness. In December 2007, 68% of all new prescriptions were transferred electronically in Sweden. The aim (...) of the present study was to assess the quality of ePrescriptions by comparing the proportions of ePrescriptions and non-electronic prescriptions necessitating a clarification contact (correction, completion or change) with the prescriber at the time of dispensing.A direct observational study was performed at three Swedish mail-order pharmacies which were known to dispense a large proportion of ePrescriptions (38-75%). Data were gathered on all ePrescriptions dispensed at these pharmacies over a three week

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2009 Medical Informatics and Decision Making

4111. Prevention of thromboembolic events in surgical patients through the creation and implementation of a computerized risk assessment program. (PubMed)

and implement a computerized DVT risk assessment program in the electronic medical record and determine its effect on compliance with DVT prophylaxis guidelines.A standardized DVT risk assessment program was developed and incorporated into the Computerized Patient Record System for all surgical patients at the Jesse Brown Veterans Affairs Medical Center. Four hundred consecutive surgical patients before and after implementation were evaluated for DVT risk, the prescription of pharmacological and mechanical (...) %) (P < .001). The assessment also improved use of prophylaxis postoperatively, increasing SCD use by 27% (P < .001). With respect to DVT occurrence, there was an 80% decrease in the incidence of postoperative DVT at 30 days and a 36% decrease at 90 days; however, this did not reach statistical significance due to the low event rate.The creation and implementation of a standardized DVT risk assessment program in the electronic medical record significantly increased use of pharmacological

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2009 Journal of Vascular Surgery

4112. Referral and treatment patterns for complex regional pain syndrome in the Netherlands. (PubMed)

Referral and treatment patterns for complex regional pain syndrome in the Netherlands. Patients with complex regional pain syndrome (CRPS) are seen and treated by a variety of physicians. The present study aims to describe referral and treatment patterns for CRPS patients in the Netherlands.Patients, who were selected (1996-2005) from an electronic general practice (GP) database (Integrated Primary Care Information Project), were invited for study participation, involving diagnosis verification (...) scavenger prescription (plus physiotherapy) as the initial treatment step for CRPS. Until 2005 only half of the patients received a scavenger within 3 months after disease onset, and the majority presents first at the GP, in particular GPs may be encouraged to initiate treatment with scavengers, while waiting for the results of further specialist consultation.

2009 Acta Anaesthesiologica Scandinavica

4113. Overrides of medication alerts in ambulatory care. (PubMed)

, 2006, through September 30, 2006. We used multivariate techniques to examine factors associated with alert acceptance.A total of 6.6% of electronic prescription attempts generated alerts. Clinicians accepted 9.2% of drug interaction alerts and 23.0% of allergy alerts. High-severity interactions accounted for most alerts (61.6%); clinicians accepted high-severity alerts slightly more often than moderate- or low-severity interaction alerts (10.4%, 7.3%, and 7.1%, respectively; P < .001). Clinicians (...) Overrides of medication alerts in ambulatory care. Electronic prescribing systems with decision support may improve patient safety in ambulatory care by offering drug allergy and drug interaction alerts. However, preliminary studies show that clinicians override most of these alerts.We performed a retrospective analysis of 233 537 medication safety alerts generated by 2872 clinicians in Massachusetts, New Jersey, and Pennsylvania who used a common electronic prescribing system from January 1

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2009 Archives of Internal Medicine

4114. Factors associated with first-fill adherence rates for diabetic medications: a cohort study. (PubMed)

Factors associated with first-fill adherence rates for diabetic medications: a cohort study. Little is known about first-fill adherence rates for diabetic medications and factors associated with non-fill.To assess the proportion of patients who fill their initial prescription for a diabetes medication, understand characteristics associated with prescription first-fill rates, and examine the effect of first-fill rates on subsequent A1c levels.Retrospective, cohort study linking electronic health (...) records and pharmacy claims.One thousand one hundred thirty-two patients over the age of 18 who sought care from the Geisinger Clinic, had Geisinger Health Plan pharmacy benefits, and were prescribed a diabetes medication for the first time between 2002 and 2006.The primary outcome of interest was naïve prescription filled by the patient within 30 days of the prescription order date.The overall first-fill adherence rate for antidiabetic drugs was 85%. Copays < $10 (OR 2.22, 95% CI 1.57-3.14

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2009 Journal of General Internal Medicine

4115. Comparing the effectiveness of aripiprazole and quetiapine in schizophrenia and related psychoses: a naturalistic, retrospective chart review study. (PubMed)

and compare those who had a good clinical response.We conducted an electronic chart review of a sample of all people attending secondary mental health care in the county of Lanarkshire, Scotland, who were treated with aripiprazole or quetiapine for schizophrenia and related psychoses (ICD-10 criteria) between 2002 and 2007. To measure effectiveness, we retrospectively assigned Clinical Global Impressions (CGI) scores and examined medication discontinuation rates.Eighty-nine patients were started (...) on treatment with aripiprazole and 132 patients with quetiapine over the 5-year period. Those treated with quetiapine had a higher initial illness severity (CGI-Severity of Illness scale) (p = .0003), were more likely to be starting rather than switching antipsychotics (p = .0003), were more likely to have a mood disorder (p = .03), were less likely to be treatment resistant (p = .005), and had lower rates of prescription of additional antipsychotics (p = .009). After adjusting for these variables

2009 Journal of Clinical Psychiatry

4116. Implementation of patient safety strategies in European hospitals. (PubMed)

test.Structures and plans for safety (including responsibilities regarding patient safety management) are well developed in most of the hospitals that participated in this study. The study found greater variation regarding the implementation of mechanisms or activities to promote patient safety, such as electronic drug prescription systems, guidelines for prevention of wrong patient, wrong site and wrong surgical procedure, and adverse events reporting systems. In the sample of hospitals that underwent audit

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2009 Quality and Safety in Health Care

4117. The association between ACE inhibitors and the complex regional pain syndrome: Suggestions for a neuro-inflammatory pathogenesis of CRPS. (PubMed)

Primary Care Information (IPCI) database in the Netherlands. Cases were identified from electronic records (1996-2005) and included if they were confirmed during an expert visit (using IASP criteria), or if they had been diagnosed by a medical specialist. Up to four controls per cases were selected, matched on gender, age, calendar time, and injury. Exposure to angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor antagonists, beta-blockers, calcium channel blockers, and diuretics (...) was assessed from the automated prescription records. Data were analyzed using multivariate conditional logistic regression. A total of 186 cases were matched to 697 controls (102 confirmed during an expert visit plus 84 with a specialist diagnosis). Current use of ACE inhibitors was associated with an increased risk of CRPS (OR(adjusted): 2.7, 95% CI: 1.1-6.8). The association was stronger if ACE inhibitors were used for a longer time period (OR(adjusted): 3.0, 95% CI: 1.1-8.1) and in higher dosages

2009 Pain

4118. Comparison of methods to assess medication adherence and classify nonadherence. (PubMed)

of different cut-points for defining nonadherence.Data were analyzed from 2 similarly designed randomized controlled trials that assessed a pharmacist's intervention to improve medication adherence among patients with hypertension or heart failure. For each participant, adherence was measured by patient self-report, prescription refill records, and electronic lids on medication containers. Agreement among measures was assessed using Spearman's correlation coefficient rho. Correlation coefficients were (...) compared by patient characteristics using Fisher's Z transformation. The sensitivity and specificity of different cut-points for defining nonadherence were calculated.Median adherence was 84% for self-report, 86% for electronic, and 91% for prescription refill adherence measurement. Refill and electronic adherence demonstrated the best agreement among measures (rho = 0.48). Age, depression, and other comorbid conditions influenced agreement among measures. Measures were generally in agreement

2009 The Annals of pharmacotherapy Controlled trial quality: uncertain

4119. Senna

Senna Senna: MedlinePlus Supplements The navigation menu has been collapsed. Menu Show Search Search MedlinePlus GO You Are Here: → → → Senna URL of this page: https://medlineplus.gov/druginfo/natural/652.html Senna To use the sharing features on this page, please enable JavaScript. What is it? Senna is an herb. The leaves and the fruit of the plant are used to make medicine. Senna is an FDA-approved over-the-counter (OTC) laxative. A prescription is not required to purchase senna. It is used (...) . A., Dominguez Alvarez, L. M., Landeiro, Aller E., Tesouro, Rodriguez, I, Gonzalez Simon, M. C., Mendez Veloso, M. C., and Pena, Perez L. [Comparative study of the efficacy and tolerance of 2 types of colon cleansing]. Rev.Esp.Enferm.Dig. 1995;87:785-791. . de Witte, P. Metabolism and pharmacokinetics of anthranoids. Pharmacology 1993;47 Suppl 1:86-97. . Mengs, U. and Rudolph, R. L. Light and electron-microscopic changes in the colon of the guinea pig after treatment with anthranoid and non-anthranoid

2009 National Centre for Complementary and Alternative Medicine

4120. Magnets

. Made from metal or alloys, magnets vary considerably in their strength. Magnets marketed for pain are usually encased in a wrap or sold in a product that is placed against the skin near where pain is felt. Different types of magnets have been studied for pain. Static or permanent magnets : Static magnets have magnetic fields that do not change. The activity of electrons in the metal causes it to be magnetic. These magnets usually aren’t very strong and are often put in products such as shoe insoles (...) devices, there isn’t much good information on the possible side effects of magnets, but few problems have been reported. Children may swallow or accidentally inhale small magnets, which can be deadly. Do not use static magnets or electromagnets that you can buy without a prescription to postpone seeing a health care provider about pain or any other medical problem. For Consumers General Information ( ( ( (MedlinePlus) Ongoing Medical Studies (ClinicalTrials.gov) For Health Professionals NCCIH Clinical

2009 National Centre for Complementary and Alternative Medicine

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