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Electrocardiogram Validity

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1. Remote electrocardiogram (ECG) interpretation consultancy services to aid diagnosis and decision making in the primary care setting

Remote electrocardiogram (ECG) interpretation consultancy services to aid diagnosis and decision making in the primary care setting Remote ECG Interpretation (ambulatory testing in the community) - Health Technology Wales > Remote ECG Interpretation (ambulatory testing in the community) Remote ECG Interpretation (ambulatory testing in the community) Topic Status Complete Remote electrocardiogram (ECG) interpretation consultancy services to aid diagnosis and decision making in the primary care (...) setting. Summary Health Technology Wales researchers searched for evidence on the use of remote electrocardiogram (ECG) interpretation consultancy services for the testing of people with suspected cardiovascular disease. HTW’s Assessment Group concluded not to progress this topic further because there is limited evidence on the use of this technology.Health Technology Wales researchers searched for evidence on the use of remote electrocardiogram (ECG) interpretation consultancy services

2019 Health Technology Wales

2. Development and external validation of new nomograms by adding ECG changes (ST depression or tall T wave) and age to conventional scoring systems to improve the predictive capacity in patients with subarachnoid haemorrhage: a retrospective, observational Full Text available with Trip Pro

Development and external validation of new nomograms by adding ECG changes (ST depression or tall T wave) and age to conventional scoring systems to improve the predictive capacity in patients with subarachnoid haemorrhage: a retrospective, observational To develop new nomograms by adding ECG changes (ST depression or tall T wave) and age to three conventional scoring systems, namely, World Federation of Neurosurgical Societies (WFNS) scale, Hunt and Hess (HH) system and Fisher scale, that can (...) predict prognosis in patients with subarachnoid haemorrhage (SAH) using our preliminary research results and to perform external validation of the three new nomograms.Retrospective, observational study SETTING: Emergency departments (ED) of two university-affiliated tertiary hospital between January 2009 and March 2015.Adult patients with SAH were enrolled. Exclusion criteria were age <19 years, no baseline ECG, cardiac arrest on arrival, traumatic SAH, referral from other hospital and referral

2019 BMJ open

3. Prospective validation of current quantitative electrocardiographic criteria for ST-elevation myocardial infarction. (Abstract)

Prospective validation of current quantitative electrocardiographic criteria for ST-elevation myocardial infarction. Rapid and reliable diagnosis of ST-elevation myocardial infarction (STEMI) as a surrogate for acute coronary occlusion is critical for early reperfusion therapy.We aimed to examine the diagnostic performance of current guideline-recommended Electrocardiogram (ECG) STEMI criteria.In a prospective diagnostic multicenter study, we objectively quantified the extent of ST-segment (...) elevation in all ECG leads using an automated software-based analysis of the digital 12-lead-ECG in adult patients presenting to the emergency department (ED) with suspected myocardial infarction (MI). Classification according to current guideline-recommended ECG criteria for STEMI at ED presentation was compared against a final diagnosis adjudicated by two independent cardiologists after reviewing all available medical records including serial ECGs, cardiac imaging and coronary angiograms.Among 2486

2019 International journal of cardiology

4. Assessment of Multi-Ion Channel Block in a Phase I Randomized Study Design: Results of the CiPA Phase I ECG Biomarker Validation Study. Full Text available with Trip Pro

Assessment of Multi-Ion Channel Block in a Phase I Randomized Study Design: Results of the CiPA Phase I ECG Biomarker Validation Study. Balanced multi-ion channel-blocking drugs have low torsade risk because they block inward currents. The Comprehensive In Vitro Proarrhythmia Assay (CiPA) initiative proposes to use an in silico cardiomyocyte model to determine the presence of balanced block, and absence of heart rate corrected J-Tpeak (J-Tpeak c) prolongation would be expected for balanced

2018 Clinical pharmacology and therapeutics Controlled trial quality: uncertain

5. Validation of beat by beat fetal heart signals acquired from four-channel fetal phonocardiogram with fetal electrocardiogram in healthy late pregnancy Full Text available with Trip Pro

Validation of beat by beat fetal heart signals acquired from four-channel fetal phonocardiogram with fetal electrocardiogram in healthy late pregnancy Fetal heart rate monitoring is an essential obstetric procedure, however, false-positive results cause unnecessary obstetric interventions and healthcare cost. In this study, we propose a low cost and non-invasive fetal phonocardiography based signal system to measure the fetal heart sounds and fetal heart rate. Phonocardiogram (PCG) signals (...) contain acoustic information reflecting the contraction and relaxation of the heart. We have developed a four-channel recording device with four separated piezoelectric sensors harnessed by a cloth sheet to record abdominal phonogram signals. A multi-lag covariance matrix based eigenvalue decomposition technique was used to extract fetal and maternal heart sounds as well as maternal breathing movement. In order to validate the fetal heart sounds extracted by PCG signal processing, 10 minutes

2018 Scientific reports

6. Validation and Opportunities of Electrocardiographic Imaging: From Technical Achievements to Clinical Applications Full Text available with Trip Pro

Validation and Opportunities of Electrocardiographic Imaging: From Technical Achievements to Clinical Applications Electrocardiographic imaging (ECGI) reconstructs the electrical activity of the heart from a dense array of body-surface electrocardiograms and a patient-specific heart-torso geometry. Depending on how it is formulated, ECGI allows the reconstruction of the activation and recovery sequence of the heart, the origin of premature beats or tachycardia, the anchors/hotspots of re (...) -entrant arrhythmias and other electrophysiological quantities of interest. Importantly, these quantities are directly and non-invasively reconstructed in a digitized model of the patient's three-dimensional heart, which has led to clinical interest in ECGI's ability to personalize diagnosis and guide therapy. Despite considerable development over the last decades, validation of ECGI is challenging. Firstly, results depend considerably on implementation choices, which are necessary to deal with ECGI's

2018 Frontiers in physiology

7. Electrocardiogram Clinical Validation Study

Electrocardiogram Clinical Validation Study Electrocardiogram Clinical Validation Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Electrocardiogram Clinical Validation Study The safety and scientific (...) Description Go to Brief Summary: The purpose of the study is to confirm the software's ability to create a Lead-1 electrocardiogram (ECG) that is clinically equivalent to a reference device. Also, to confirm a rhythm classification algorithm and its ability to detect and classify heart rhythms into two categories (Sinus Rhythm or Atrial Fibrillation) using a single Lead ECG. Condition or disease Intervention/treatment Phase Atrial Fibrillation Other: 1-Lead ECG Device: 12-Lead ECG Not Applicable Study

2018 Clinical Trials

8. Validation of the Prognostic Utility of the Electrocardiogram for Acute Drug Overdose Full Text available with Trip Pro

Validation of the Prognostic Utility of the Electrocardiogram for Acute Drug Overdose While it is certain that some emergency department patients with acute drug overdose suffer adverse cardiovascular events (ACVE), predicting ACVE is difficult. The prognostic utility of the ECG for heterogeneous drug overdose patients remains to be proven. This study was undertaken to validate previously derived features of the initial ECG associated with ACVE in this population.We performed a prospective (...) validation cohort study to evaluate adult emergency department patients with acute drug overdose at 2 urban university hospitals over 5 years in whom an emergency department admission ECG was performed. Exclusion criteria were alternate diagnoses, anaphylaxis, chronic drug toxicity, and missing outcome data. ACVE was defined as any of the following: circulatory shock, myocardial injury, ventricular dysrhythmia, or cardiac arrest. Blinded cardiologists interpreted ECGs for previously derived predictors

2017 Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

9. Validity of electrocardiographic criteria for increased left ventricular mass in young patients in the general population Full Text available with Trip Pro

Validity of electrocardiographic criteria for increased left ventricular mass in young patients in the general population To investigate validity of electrocardiographic (ECG) criteria for left ventricular hypertrophy (LVH) in young adults.Retrospectively, echocardiograms showing LVH and concomitant electrocardiograms were collected in patients 18 to 39 years old. A control group of patients without LVH was collected. Using echocardiogram as the gold standard, electrocardiograms were analyzed (...) using common voltage criteria.Study included 100 subjects (52% male, mean age = 28 ± 6.8 years, 96% Hispanic or African-American) with 50% LVH prevalence. Sensitivity and specificity for Sokolow-Lyon criteria were 24% (95%CI: 13.5%-38.4%) and 88% (95%CI: 74.9%-95%). For Cornell criteria, sensitivity was 32% (95%CI: 19.9%-46.8%) and specificity 98% (95%CI: 87.9%-99.8%). For R in aVL criteria, sensitivity was 12% (95%CI: 4.9%-25%) and specificity 100% (95%CI: 91.1%-100%).In young adults common ECG

2017 World journal of cardiology

10. CiPA Phase 1 ECG Biomarker Validation Study

CiPA Phase 1 ECG Biomarker Validation Study CiPA Phase 1 ECG Biomarker Validation Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. CiPA Phase 1 ECG Biomarker Validation Study The safety and scientific (...) Purpose: Other Official Title: Comprehensive in Vitro Proarrhythmia Assay (CiPA) Clinical Phase 1 ECG Biomarker Validation Study (CiPA Phase 1 ECG Biomarker Study) Actual Study Start Date : March 14, 2017 Actual Primary Completion Date : June 26, 2017 Actual Study Completion Date : June 26, 2017 Resource links provided by the National Library of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: Ranolazine Ranolazine 1500 mg two times per day for 2.5

2017 Clinical Trials

11. Design and validation of a three-instrument toolkit for the assessment of competence in electrocardiogram rhythm recognition. Full Text available with Trip Pro

. The following three instruments were developed and psychometrically tested: an electrocardiogram knowledge assessment tool (ECG-KAT), an electrocardiogram skills assessment tool (ECG-SAT) and an electrocardiogram self-efficacy assessment tool (ECG-SES). Reliability and validity (content, criterion and construct) of these tools were meticulously examined.A high Cronbach's alpha coefficient demonstrated the excellent reliability of the instruments (ECG-KAT=0.89; ECG-SAT=0.93; ECG-SES=0.98). An excellent (...) Design and validation of a three-instrument toolkit for the assessment of competence in electrocardiogram rhythm recognition. Rapid and accurate interpretation of cardiac arrhythmias by nurses has been linked with safe practice and positive patient outcomes. Although training in electrocardiogram rhythm recognition is part of most undergraduate nursing programmes, research continues to suggest that nurses and nursing students lack competence in recognising cardiac rhythms. In order to promote

2017 European Journal of Cardiovascular Nursing

12. AF Stroke Substudy SL-ECG Versus 12lead ECG

Outcome Measures : Analysis of SL-ECGs and validation of prognostic factors based person-specific data and their medical history. [ Time Frame: 12 Month ] The descriptive analysis is performed comprehensively for the entire cohort and separately for people with known and newly discovered atrial fibrillation. The SL-ECG, person-specific data (e.g. age, BMI) and medical history (e.g. cardiovascular diseases, drug intake) are used to validate known prognostic factors and to find new prognostic factors (...) to Additional Information: Publications: Layout table for additonal information Responsible Party: RWTH Aachen University ClinicalTrials.gov Identifier: Other Study ID Numbers: 18-078 First Posted: October 23, 2018 Last Update Posted: October 23, 2018 Last Verified: October 2018 Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by RWTH Aachen University: ECG measurement AF-Stroke Germany Electrocardiogram

2018 Clinical Trials

13. Electrocardiogram Validity

RAY TUBE DISPLAY. Concepts Diagnostic Procedure ( T060 ) MSH ICD9 89.52 SnomedCT 164960001 , 164844004 , 146485007 , 142135006 , 142007005 , 271334005 , 46825001 , 29303009 LNC LP6244-0, LP100599-2, LP57609-7 English ECG , EKG , electrocardiography , Electrocardiography NOS , Electrocardiography NOS (regime/therapy) , ELECTROCARDIOGR , electrocardiogram (procedure) , electrocardiogram , Electrocardiograph , Electrocardiography (procedure) , Electrocardiography NOS (procedure) , Electrocardiographs (...) , Electrocardiogram , Electrocardiographic procedure (procedure) , Electrocardiographic procedure , Electrocardiographic procedure, NOS , Electrocardiogram, NOS , EKG (Electrophysiology) , ECG NOS , Electrocardiography Italian Elettrocardiogramma , ECG , EKG , Elettrocardiografia French ECG , EKG , ECG (ÉlectroCardioGraphie) , Electrocardiogramme , Électrocardiographie Swedish Elektrokardiografi Spanish electrocardiografía, SAI (régimen/tratamiento) , electrocardiografía, SAI (procedimiento) , Electrocardiography

2018 FP Notebook

14. A Review Of SonoHealth’s EKGraph Portable ECG Monitor: Comparison To Apple Watch ECG And AliveCor’s Kardia ECG

the validity of any review on the company website or Amazon. Let The (Mobile ECG) Buyer Beware The SonoHealth EKGraph is capable of making a reasonable quality single lead ECG. Presumably all the other devices utilizing the same hardware will work as well. However, the utility of these devices for consumers and patients lies in the ability of the software algorithms to provide accurate diagnoses of the cardiac rhythm. Apple Watch 4 and mobile ECG do a very good job of sorting out atrial fibrillation from (...) : Comparison To Apple Watch ECG And AliveCor’s Kardia ECG” says: ACP is analytical and should be carefully read. He makes sense to me. HRS, MD, FACC Loading... Glad to see you are keeping up on information about new portable EKG devices. So far I like my Kardia device. Loading... I bought an Apple 4 Watch when it became available to measure my exercise. Two hours after first putting it on I thought it was broken when it said I might have “atrial fibrillation,” something I never heard of. When it continued

2019 The Skeptical Cardiologist

15. Comparative Analysis of the Equivital EQ02 Lifemonitor with Holter Ambulatory ECG Device for Continuous Measurement of ECG, Heart Rate, and Heart Rate Variability: A Validation Study for Precision and Accuracy Full Text available with Trip Pro

Comparative Analysis of the Equivital EQ02 Lifemonitor with Holter Ambulatory ECG Device for Continuous Measurement of ECG, Heart Rate, and Heart Rate Variability: A Validation Study for Precision and Accuracy Background: The Equivital (EQ02) is a multi-parameter telemetric device offering both real-time and/or retrospective, synchronized monitoring of ECG, HR, and HRV, respiration, activity, and temperature. Unlike the Holter, which is the gold standard for continuous ECG measurement, EQO2 (...) continuously monitors ECG via electrodes interwoven in the textile of a wearable belt. Objective: To compare EQ02 with the Holter for continuous home measurement of ECG, heart rate (HR), and heart rate variability (HRV). Methods: Eighteen healthy participants wore, simultaneously for 24 h, the Holter and EQ02 monitors. Per participant, averaged HR, and HRV per 5 min from the two devices were compared using Pearson correlation, paired T-test, and Bland-Altman analyses. Accuracy and precision metrics

2016 Frontiers in physiology

16. Mouse ECG findings in aging, with conduction system affecting drugs and in cardiac pathologies: Development and validation of ECG analysis algorithm in mice Full Text available with Trip Pro

Mouse ECG findings in aging, with conduction system affecting drugs and in cardiac pathologies: Development and validation of ECG analysis algorithm in mice Mouse models are extremely important in studying cardiac pathologies and related electrophysiology, but very few mouse ECG analysis programs are readily available. Therefore, a mouse ECG analysis algorithm was developed and validated. Surface ECG (lead II) was acquired during transthoracic echocardiography from C57Bl/6J mice under (...) isoflurane anesthesia. The effect of aging was studied in young (2-3 months), middle-aged (14 months) and old (20-24 months) mice. The ECG changes associated with pharmacological interventions and common cardiac pathologies, that is, acute myocardial infarction (AMI) and progressive left ventricular hypertrophy (LVH), were studied. The ECG raw data were analyzed with an in-house ECG analysis program, modified specially for mouse ECG. Aging led to increases in P-wave duration, atrioventricular conduction

2015 Physiological reports

17. Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval--A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity. Full Text available with Trip Pro

Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval--A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity. E-52862 is a Sigma-1 receptor antagonist (S1RA) currently under investigation as a potential analgesic medicine. We successfully applied a concentration-effect model retrospectively to a four-way crossover Phase I single ascending dose study (...) and utilized the QTc shortening effects of a meal to demonstrate assay sensitivity by establishing the time course effects from baseline in all four periods, independently from any potential drug effects.Thirty two healthy male and female subjects were included in four treatment periods to receive single ascending doses of 500 mg, 600 mg or 800 mg of E-52862 or placebo. PK was linear over the dose range investigated and doses up to 600 mg were well tolerated. The baseline electrocardiography (ECG

2015 PloS one Controlled trial quality: uncertain

18. An artificial intelligence-enabled ECG algorithm for the identification of patients with atrial fibrillation during sinus rhythm: a retrospective analysis of outcome prediction. (Abstract)

fibrillation using machine learning.We developed an artificial intelligence (AI)-enabled electrocardiograph (ECG) using a convolutional neural network to detect the electrocardiographic signature of atrial fibrillation present during normal sinus rhythm using standard 10-second, 12-lead ECGs. We included all patients aged 18 years or older with at least one digital, normal sinus rhythm, standard 10-second, 12-lead ECG acquired in the supine position at the Mayo Clinic ECG laboratory between Dec 31, 1993 (...) , and July 21, 2017, with rhythm labels validated by trained personnel under cardiologist supervision. We classified patients with at least one ECG with a rhythm of atrial fibrillation or atrial flutter as positive for atrial fibrillation. We allocated ECGs to the training, internal validation, and testing datasets in a 7:1:2 ratio. We calculated the area under the curve (AUC) of the receiver operatoring characteristic curve for the internal validation dataset to select a probability threshold, which we

2019 Lancet

19. Predicting sudden cardiac death in a general population using an electrocardiographic risk score Full Text available with Trip Pro

Predicting sudden cardiac death in a general population using an electrocardiographic risk score We investigated whether combining several ECG abnormalities would identify general population subjects with a high sudden cardiac death (SCD) risk.In a sample of 6830 participants (mean age 51.2±13.9 years; 45.5% male) in the Mini-Finland Health Survey, a general population cohort representative of the Finnish adults aged ≥30 years conducted in 1978-1980, we examined their ECGs, following subjects (...) for 24.3±10.4 years. We analysed the association between individual ECG abnormalities and 10-year SCD risk and developed a risk score using five ECG abnormalities independently associated with SCD risk: heart rate >80 beats per minute, PR duration >220 ms, QRS duration >110 ms, left ventricular hypertrophy and T-wave inversion. We validated the score using an external general population cohort of 10 617 subjects (mean age 44.0±8.5 years; 52.7% male).No ECG abnormalities were present in 4563 subjects

2019 EvidenceUpdates

20. Association of Implementation of Practice Standards for Electrocardiographic Monitoring With Nurses' Knowledge, Quality of Care, and Patient Outcomes: Findings From the Practical Use of the Latest Standards of Electrocardiography (PULSE) Trial. Full Text available with Trip Pro

Association of Implementation of Practice Standards for Electrocardiographic Monitoring With Nurses' Knowledge, Quality of Care, and Patient Outcomes: Findings From the Practical Use of the Latest Standards of Electrocardiography (PULSE) Trial. Although continuous electrocardiographic (ECG) monitoring is ubiquitous in hospitals, monitoring practices are inconsistent. We evaluated implementation of American Heart Association practice standards for ECG monitoring on nurses' knowledge, quality (...) of care, and patient outcomes.The PULSE (Practical Use of the Latest Standards of Electrocardiography) Trial was a 6-year multisite randomized clinical trial with crossover that took place in 65 cardiac units in 17 hospitals. We measured outcomes at baseline, time 2 after group 1 hospitals received the intervention, and time 3 after group 2 hospitals received the intervention. Measurement periods were 15 months apart. The 2-part intervention consisted of an online ECG monitoring education program

2017 Circulation. Cardiovascular quality and outcomes Controlled trial quality: uncertain

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