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Ectopic Pregnancy

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61. Demographic, lifestyle, and reproductive risk factors for ectopic pregnancy. Full Text available with Trip Pro

Demographic, lifestyle, and reproductive risk factors for ectopic pregnancy. To evaluate the relationship between demographic, lifestyle, and reproductive factors and the risk of ectopic pregnancy (EP).Prospective cohort.United States.Nurses' Health Study II cohort comprising 41,440 pregnancies from 22,356 women.Demographic, lifestyle, and reproductive factors self-reported in 1989 then updated every 2 years. Multivariable log-binomial regression models with generalized estimating equations (...) were used to estimate adjusted risk ratios (aRR).Ectopic pregnancy.Incident EP was reported in 411 (1.0%) pregnancies. Former and current smokers had 1.22 (95% confidence interval [CI], 0.97-1.55) and 1.73 (95% CI, 1.28-2.32) times, respectively, the risk of EP compared with never smokers. The risk of EP 10 years after quitting was similar to never smokers (aRR 0.90; 95% CI, 0.60-1.33). Women consuming ≥10 g/day of alcohol had 1.50 (95% CI, 1.08-2.09) times the risk of EP compared with never

2018 Fertility and Sterility

62. Ectopic pregnancy incidence in the Republic of Korea in 2009–2015: A population-based cross-sectional study Full Text available with Trip Pro

Ectopic pregnancy incidence in the Republic of Korea in 2009–2015: A population-based cross-sectional study We estimated the incidence of ectopic pregnancy (EP) and the success rate of expectant management of EP in South Korea. We analyzed data from 2009 to 2015 using the Health Insurance Review and Assessment Service National Inpatient Sample (HIRA-NIS) database. EP was identified by diagnostic codes, and strict EP was identified by both diagnostic codes and treatment codes. From 2009 (...) to 2015, 369,701 cases of EP, abortion, or delivery were extracted from a total of 4,476,495 women. Of the total pregnancies, 8,556 cases were EPs. The incidence of EP was 34.1 ± 0.7 per 1,000 pregnancies and the incidence of strict EP was 17.3 ± 0.3 per 1,000 pregnancies. Among women aged 25-44 years, age was associated with a higher incidence of EP (odds ratio [OR]: 1.13; 95% confidence interval [CI]: 1.06, 1.19; P < 0.01). The incidence rates of EP (OR: 0.99; 95% CI: 0.97, 1.01; P = 0.51) did

2018 Scientific reports

63. Comparison of Four Methods of Treating Ectopic Pregnancy: A Retrospective Cohort Study Full Text available with Trip Pro

Comparison of Four Methods of Treating Ectopic Pregnancy: A Retrospective Cohort Study To compare the results of expectant management, single and multidose methotrexate (MTX) and surgical management of ectopic pregnancy (EP).In this retrospective cohort study, the original files of 233 patients who were treated for EP between May 2009 and December 2016 were analyzed. The patients were assigned to the following groups based on the applied treatment methods: Group 1, expectant management (n = 24 (...) ), Group 2, single-dose MTX (n = 144), Group 3, multiple-dose MTX (n = 25), and Group 4, surgical intervention (n = 40). The following parameters were recorded and assessed: sociodemographic characteristics, pelvic ultrasonography findings (gestational sac, ectopic mass appearance, positive fetal cardiac activity), serum beta-human chorionic gonadotropin (β-hCG) levels on Day 0, Day 4, and Day 7, and surgical procedures in women that underwent surgical interventions.The sociodemographic characteristics

2018 Geburtshilfe Und Frauenheilkunde

64. Acute intestinal obstruction due to extrinsic compression by previa myoma and ectopic pregnancy: a case report Full Text available with Trip Pro

Acute intestinal obstruction due to extrinsic compression by previa myoma and ectopic pregnancy: a case report Acute intestinal obstruction during pregnancy is a rare digestive surgical emergency with significant maternal and fetal mortality. Diagnosis is difficult, often delaying the management. Here, we report an exceptional association of mechanical acute intestinal obstruction due to compression by previa uterine leiomyoma, and a ruptured ectopic pregnancy.This is the case report of a 43 (...) an empty rectum, and the mass was perceptible in Douglas's pouch. At the vaginal examination, we found the same mass and a finger holster was clean. The diagnosis of intestinal occlusion by a tumor was retained. The laparotomy revealed a distended intestine, a ruptured right tubal ectopic pregnancy and a polymyomatous uterus. The most massive previa leiomyoma was adhering and compressing the rectal and sigmoidal hinge. A total hysterectomy was performed and histopathological examination of specimens

2018 Journal of medical case reports

65. Vinorelbine Potently Induces Placental Cell Death, Does Not Harm Fertility and is a Potential Treatment for Ectopic Pregnancy Full Text available with Trip Pro

Vinorelbine Potently Induces Placental Cell Death, Does Not Harm Fertility and is a Potential Treatment for Ectopic Pregnancy Ectopic pregnancies complicate 1-2 pregnancies and are a leading cause of maternal death. An effective oral drug therapy that replaces surgery might make its treatment safer, cheaper, simpler and therefore more widely accessible. The only current medical treatment offered to women is intramuscular methotrexate, but this only reliably resolves smaller ectopic pregnancies (...) . As such, many ectopic pregnancies require surgical excision. We show that vinorelbine, an orally available chemotherapeutic agent, potently induced placental cell death but did not harm fertility in mice. Vinorelbine was 100-1000 times more potent than methotrexate in inducing placental cell death in vitro, and more potent than combination methotrexate and gefitinib (another proposed treatment for ectopic pregnancy being evaluated in phase III trials). Mechanistically, it caused microtubule condensation

2018 EBioMedicine

66. An audit of the management of ectopic pregnancies in a district hospital, Gauteng, South Africa Full Text available with Trip Pro

An audit of the management of ectopic pregnancies in a district hospital, Gauteng, South Africa  Ectopic pregnancy (EP) is a life-threatening condition; at Odi Hospital, approximately 7-10 EPs are managed weekly. Our study is the first to assess the management of this life-threatening condition at Odi Hospital. This study aimed to determine the incidence of EP and to assess the profile of women who presented with EP at Odi District Hospital from 01 January 2010 to 31 December 2014. The study

2018 African journal of primary health care & family medicine

67. A multi-centre, double-blind, placebo-controlled, randomised trial of combination methotrexate and gefitinib versus methotrexate alone to treat tubal ectopic pregnancies (GEM3): trial protocol Full Text available with Trip Pro

A multi-centre, double-blind, placebo-controlled, randomised trial of combination methotrexate and gefitinib versus methotrexate alone to treat tubal ectopic pregnancies (GEM3): trial protocol Tubal ectopic pregnancy (tEP) is the most common life-threatening condition in gynaecology. Treatment options include surgery and medical management. Stable women with tEPs with pre-treatment serum human chorionic gonadotrophin (hCG) levels < 1000 IU/L respond well to outpatient medical treatment

2018 Trials Controlled trial quality: predicted high

68. Gefitinib and Methotrexate to Treat Ectopic Pregnancies with a Pre-Treatment Serum hCG 1000–10,000 IU/L: Phase II Open Label, Single Arm Multi-Centre Trial Full Text available with Trip Pro

Gefitinib and Methotrexate to Treat Ectopic Pregnancies with a Pre-Treatment Serum hCG 1000–10,000 IU/L: Phase II Open Label, Single Arm Multi-Centre Trial Ectopic pregnancies are a leading cause of maternal mortality. Most are treated surgically. We evaluated the efficacy and safety of combining oral gefitinib (epidermal growth factor receptor inhibitor) with methotrexate to treat larger ectopic pregnancies.We performed a phase II, single arm, open label study across four hospitals (...) in Edinburgh and Melbourne. We recruited women with a stable tubal ectopic pregnancy and a pre-treatment serum hCG between 1000 and 10,000 IU/L. We administered intramuscular methotrexate (50 mg/m2) once, and oral gefitinib (250 mg) for seven days. The primary outcome was the percentage successfully treated without needing surgery. To show the treatment is at least 70% effective, 28 participants were required, and 24 or more successfully treated without surgery. Secondary outcomes were safety, tolerability

2018 EBioMedicine

69. Myomectomy scar ectopic pregnancy following a cryopreserved embryo transfer Full Text available with Trip Pro

Myomectomy scar ectopic pregnancy following a cryopreserved embryo transfer A 40 year old woman with a history of a myomectomy visited the Department of Obstetrics and Gynecology, Niigata University Medical and Dental Hospital, Niigata, Japan, following 2 years of infertility. Magnetic resonance imaging detected an abnormal endometrial-like pseudo-cavity. A hysterosalpingography also revealed an abnormal accumulation of contrast medium at the myometrial scar site. A transvaginal ultrasound (...) transvaginal ultrasonography.A subserosal uterine pregnancy is a rare form of intramural pregnancy, which is a rare subtype of an ectopic pregnancy, which could occur at the myomectomy site, especially after an embryo transfer. It is believed that this rare ectopic pregnancy resulted from embryo implantation under the serosa through a micro-sinus tract that was a site of suture failure of the myomectomy scar and was partially affected by the embryo transfer. Clinicians should consider the possibility

2018 Reproductive Medicine and Biology

70. The effectiveness of different treatments for cesarean ectopic pregnancy. Full Text available with Trip Pro

The effectiveness of different treatments for cesarean ectopic pregnancy. 29878597 2019 02 08 2019 02 15 1471-0528 125 13 2018 12 BJOG : an international journal of obstetrics and gynaecology BJOG The effectiveness of different treatments for caesarean ectopic pregnancy. 1671 10.1111/1471-0528.15314 Agostini A A Department of Gynaecology and Obstetrics, La Conception Hospital, Marseille, France. Crochet P P Department of Gynaecology and Obstetrics, Arnaud de Villeneuve Hospital, Montpellier (...) , France. eng Journal Article Comment 2018 06 28 England BJOG 100935741 1470-0328 AIM IM BJOG. 2018 Dec;125(13):1663-1670 29697890 Cesarean Section Cicatrix Cohort Studies Female Humans Pregnancy Pregnancy, Ectopic United Kingdom 2018 6 8 6 0 2019 2 9 6 0 2018 6 8 6 0 ppublish 29878597 10.1111/1471-0528.15314

2018 BJOG

71. Expectant management of tubal ectopic pregnancy: a systematic review and meta-analysis

Expectant management of tubal ectopic pregnancy: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites

2020 PROSPERO

72. Anesthetic efficacy of propofol combined with butorphanol in laparoscopic surgery for ectopic pregnancy

Anesthetic efficacy of propofol combined with butorphanol in laparoscopic surgery for ectopic pregnancy Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files

2020 PROSPERO

73. Anesthetic effect of propofol combined with butorphanol (PB) in laparoscopic surgery (LS) for ectopic pregnancy (EP): a protocol of systematic review

Anesthetic effect of propofol combined with butorphanol (PB) in laparoscopic surgery (LS) for ectopic pregnancy (EP): a protocol of systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content

2020 PROSPERO

74. Does propofol combined butorphanol (PB) have anesthetic efficacy on pain relief in laparoscopic surgery (LS) for ectopic pregnancy (EP): a protocol of systematic review and meta-analysis?

Does propofol combined butorphanol (PB) have anesthetic efficacy on pain relief in laparoscopic surgery (LS) for ectopic pregnancy (EP): a protocol of systematic review and meta-analysis? Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility

2020 PROSPERO

75. Comparing the different treatments option for ectopic pregnancy: a systematic review and network meta-analysis

Comparing the different treatments option for ectopic pregnancy: a systematic review and network meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files

2020 PROSPERO

76. Compare the incidence and influencing factors of ectopic pregnancy in fresh embryo transfer and frozen-thawed embryo transfer

Compare the incidence and influencing factors of ectopic pregnancy in fresh embryo transfer and frozen-thawed embryo transfer Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any

2020 PROSPERO

77. Is There a Role for Hyperglycosylated hCG in the Diagnosis of Ectopic Pregnancy in Women with a Pregnancy of Unknown Location? (Abstract)

Is There a Role for Hyperglycosylated hCG in the Diagnosis of Ectopic Pregnancy in Women with a Pregnancy of Unknown Location? OBJECTIVE: To examine the potential use of hyperglycosylated human gonadotropin (hCG-H) in identifying ectopic pregnancies in pregnancies of unknown location (PULs) on ultrasound scan. STUDY DESIGN: This was a prospective observational study. An additional blood sample was taken from women whose initial transvaginal ultrasound scan showed none of the following: intact (...) intrauterine pregnancy, retained placental tissue, or ectopic pregnancy. Parallel sandwich ELISAs were performed using sheep monoclonal antibodies to the 12F6 epitope for detection of total hCG and to the 4D8 epitope for hCG-H detection, and an automated immunoassay technique was used for progesterone and serum β-hCG measurements. Patients were managed accord-ing to our standard clinical protocol. RESULTS: hCG-H was significantly higher in ectopic pregnancies (85.6 ng/mL) than in viable intrauterine

2017 Journal of Reproductive Medicine

78. Clinical characteristics of persistent ectopic pregnancy after salpingostomy and influence on ongoing pregnancy Full Text available with Trip Pro

Clinical characteristics of persistent ectopic pregnancy after salpingostomy and influence on ongoing pregnancy The aim of this study was to assay the clinical characteristics of persistent ectopic pregnancy (PEP) and its influence on ongoing pregnancy.We retrospectively reviewed 2498 patients who received salpingostomies as primary management for ectopic pregnancies from January 2004 to December 2009, using medical records and telephone inquiries. Clinical characteristics of the 52 patients (...) monitored after surgery, which had declined by 28.31% on postoperative day (POD) 4, 40.22% on POD 7, 51.46% on POD 10 and 53.43% on POD 21. Repeat ectopic pregnancy (REP) tended to occur more frequently in PEP patients (PEP: 5 cases, 10.20%; non-PEP: 4 cases, 2.80%; P = 0.034). Multivariate analysis showed that pelvic adhesions and PEP were the strongest independent predictors of REP.Gestational age, mass size and pelvic adhesions were significantly correlated with PEP. PEP was an independent prognostic

2017 The journal of obstetrics and gynaecology research

79. Ruptured ectopic pregnancy with a negative urine pregnancy test Full Text available with Trip Pro

Ruptured ectopic pregnancy with a negative urine pregnancy test Ectopic pregnancy is commonly seen as a differential diagnosis of first-trimester vaginal bleeding. Often the diagnosis is made based on a combination of exam findings, transvaginal ultrasound, and a positive pregnancy test. Our case describes a patient with a history of ectopic pregnancy treated with methotrexate and serial human chorionic gonadotropin measurements that were decreasing appropriately. At the time of evaluation, her (...) urine pregnancy test was negative; however, she was confirmed to have a ruptured tubal ectopic pregnancy. This case highlights the variable presentation of ectopic pregnancies and the importance of combining exam findings with ultrasound and laboratory results.

2017 Proceedings (Baylor University. Medical Center)

80. Randomised controlled trial: Salpingectomy for tubal ectopic pregnancy is appropriate in the presence of healthy-looking contralateral tube

Randomised controlled trial: Salpingectomy for tubal ectopic pregnancy is appropriate in the presence of healthy-looking contralateral tube Salpingectomy for tubal ectopic pregnancy is appropriate in the presence of healthy-looking contralateral tube | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Salpingectomy for tubal ectopic pregnancy is appropriate in the presence of healthy-looking contralateral tube Article Text Therapeutics

2014 Evidence-Based Medicine

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