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Ectopic Pregnancy

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181. Is the type of gonadotropin-releasing hormone suppression protocol for ovarian hyperstimulation associated with ectopic pregnancy in fresh autologous cycles for in vitro fertilization? Full Text available with Trip Pro

Is the type of gonadotropin-releasing hormone suppression protocol for ovarian hyperstimulation associated with ectopic pregnancy in fresh autologous cycles for in vitro fertilization? To evaluate the association between different ovarian hyperstimulation protocols and ectopic pregnancy (EP) in in vitro fertilization (IVF) cycles in fresh autologous embryo transfer cycles in the United States between 2008 and 2011 as reported to the Society of Assisted Reproductive Technology (SART).Historical (...) cohort study.Not applicable.None.None.All autologous cycles that resulted in a clinical pregnancy after a fresh, intrauterine embryo transfer and described characteristics of cycles according to protocol were included: luteal GnRH agonist, GnRH agonist flare, or GnRH antagonist. Multivariate logistic regression was conducted to investigate the association between type of protocol and EP.Among 136,605 clinical pregnancies, 2,645 (1.94%) were EP. Ectopic pregnancy was more frequent with GnRH antagonist

2016 Fertility and Sterility

182. GnRH and GnRH receptor are expressed at tubal ectopic pregnancy implantation sites. Full Text available with Trip Pro

GnRH and GnRH receptor are expressed at tubal ectopic pregnancy implantation sites. To investigate whether gonadotropin-releasing hormone (GnRH) and GnRH receptor (GnRHR) are expressed at tubal ectopic pregnancy sites, and to study the potential role of GnRH signaling in regulating immortalized human trophoblast cell viability.Immunohistochemical and experimental studies.Academic research laboratory.Fallopian tube implantation sites (n = 25) were collected from women with ectopic pregnancy (...) are expressed in trophoblast cell populations and fallopian tube epithelium at tubal ectopic pregnancy sites. GnRH increases BeWo cell viability, an effect mediated by the GnRHR. Further work is required to investigate the potential role of GnRH signaling in ectopic pregnancy.Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

2016 Fertility and Sterility

183. Risk factors for ectopic pregnancy in assisted reproductive technology: a 6-year, single-center study. Full Text available with Trip Pro

Risk factors for ectopic pregnancy in assisted reproductive technology: a 6-year, single-center study. To explore factors affecting the incidence of ectopic pregnancy (EP) in assisted reproductive technology (ART).A retrospective cohort study on the incidence of EPs in IVF/intracytoplasmic sperm injection (ICSI) and IUI cycles from June 2009 to August 2015. Age of patients, tubal factor infertility, type of cycle (fresh or thawed), embryo being transferred (cleavage embryo or blastocyst (...) ), and number of embryos transferred were analyzed to explore their relationship with the incidence of EP.Teaching hospital.A total of 18,432 pregnancies resulting from ART treatment were retrospectively analyzed.None.Ectopic pregnancy rate.For IVF/ICSI cycles, the incidence of EP was different between cycles transferred with cleavage embryo and blastocyst (3.45% vs. 2.47%). In multivariate logistic regression analysis, tubal infertility was associated with EP (adjusted odds ratio 1.716, 95% confidence

2016 Fertility and Sterility

184. Primary Ovarian Ectopic Pregnancy: Still a Medical Challenge. (Abstract)

Primary Ovarian Ectopic Pregnancy: Still a Medical Challenge. To investigate the clinical presentation of women with primary ovarian pregnancy diagnosed in recent years and to compare it to tubal pregnancy.Seven women treated for primary ovarian pregnancy from 2002-2013 were retrospectively identified and compared to 42 women with tubal pregnancies (involving either tubal rupture or tubal abortion) operated on during the same period. In the ovarian pregnancy group the pathology examination (...) , p<0.001). Moreover, a statistically significant difference was found when we compared postoperative hospitalization days (2 ± 0.6 vs. 1.3 ± 0.7, respectively; p=0.01) in the ovarian pregnancy group as compared with the tubal pregnancy group.Primary ovarian ectopic pregnancy is still a major challenge for early diagnosis and treatment; it is associated with rupture and massive intraabdominal bleeding.

2016 Journal of Reproductive Medicine

185. Spontaneous Bilateral Ectopic Pregnancy: A Case-Report. (Abstract)

Spontaneous Bilateral Ectopic Pregnancy: A Case-Report. Bilateral tubal pregnancies in the absence of preceding induction of ovulation are rare. They are usually diagnosed at the time of surgery.We report a case of spontaneous bilateral tubal pregnancies diagnosed intraoperatively. A 28-year-old primigravida presented with light vaginal bleeding and abdominal pain 6 weeks after her last menstrual period. Her β-hCG level was 8,240 mIU/mL. Ultrasonography showed evidence of right tubal ectopic (...) pregnancy. Laparoscopy revealed the presence of a simultaneous left tubal ectopic pregnancy. A bilateral laparoscopic salpingectomy was performed without complications, and the pathology report confirmed the diagnosis.The diagnosis of bilateral tubal pregnancy is usually made intraoperatively, thus highlighting the importance of closely examining both tubes at the time of surgery, even in the presence of significant adhesive disease.

2016 Journal of Reproductive Medicine

186. Primary Hepatic Ectopic Pregnancy: A Case Report. (Abstract)

Primary Hepatic Ectopic Pregnancy: A Case Report. Hepatic pregnancy is a very rare form of ectopic pregnancy, potentially life-threatening for the mother.A 33-year-old woman presented with intermittent pain in the upper abdomen of 5 days' duration. An abdominopelvic ultrasound scan was performed, which demonstrated hepatic pregnancy. Later, abdominal computed tomography (CT) and magnetic resonance imaging (MRI) in coronal and axial confirmed the findings and delineated exactly the regional (...) anatomy before surgery. Laparotomy was successfully performed according to the preoperative diagnosis.The application of imaging techniques (ultrasound, CT, and MRI scan) is very useful in hepatic pregnancy for defining the regional anatomy in greater detail and is critical in minimizing surgical injury.

2016 Journal of Reproductive Medicine

187. Ectopic Pregnancy After Plan B Emergency Contraceptive Use. (Abstract)

Ectopic Pregnancy After Plan B Emergency Contraceptive Use. Pregnancy outcomes after emergency contraceptive use has been debated over time, but review of the literature includes mechanisms by which these medications may increase the chance of an ectopic pregnancy. Such cases are infrequently reported, and many emergency providers may not readily consider this possibility when treating patients.This is a case presentation of ectopic pregnancy in a patient who had recently used Plan B (...) of levonorgestrel use and the incidence of ectopic pregnancies. The mechanism of action of this emergency contraceptive is addressed, and though no definite causal relationship is known between levonorgestrel and ectopic pregnancies, there is a pharmacologic explanation for how this event may occur after use of this medication. Ultimately, the emergency provider will be reminded of the importance of educating the patient on the possible outcomes after its use, including failure of an emergency contraceptive

2016 Journal of Emergency Medicine

188. [Chinese Herbs Combined Three-stage Sequential Therapy for Conservative Treatment of Ectopic Pregnancy]. (Abstract)

[Chinese Herbs Combined Three-stage Sequential Therapy for Conservative Treatment of Ectopic Pregnancy]. Objective To observe the clinical efficacy and safety of three-stage sequential thera- py [(methotrexate + mifepristone + Gongwaiyun Recipe (GR)] for conservative treatment of ectopic pregnancy. Methods Recruited were 250 ectopic pregnancy patients, who received conservative treat- ment at Affiliated Ganzhou Hospital of Nanchang University and Ruijin Maternal & Child Health Care Hos- pital (...) effective treatment for ectopic pregnancy patients who had requirement for pregnancy.

2016 Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

189. Surgical treatment of Cesarean scar ectopic pregnancy: Efficacy and safety of ultrasound-guided suction curettage. Full Text available with Trip Pro

Surgical treatment of Cesarean scar ectopic pregnancy: Efficacy and safety of ultrasound-guided suction curettage. To assess the efficacy of ultrasound-guided suction curettage for management of pregnancies implanted into the lower uterine segment Cesarean section scar.This was a retrospective study including women diagnosed with Cesarean section scar pregnancy at two large tertiary referral early pregnancy units between 1997 and 2014. Surgical evacuation was offered to selected women (...) presenting in the first trimester ≤ 14 weeks' gestation. All procedures were performed transcervically under ultrasound guidance using suction curettage. A modified Shirodkar cervical suture was used in women who required additional measures to secure hemostasis.A total of 232 women with Cesarean section scar pregnancy were seen at the referral units; 191/232 (82.3%) women were treated surgically. The median intraoperative blood loss was 100 mL (range, 10-3000 mL); 9/191 (4.7% (95% CI, 1.7-7.7%)) women

2016 Ultrasound in Obstetrics and Gynecology

190. Primary Ovarian Monochorionic Twin Ectopic Pregnancy. A Case Report. (Abstract)

Primary Ovarian Monochorionic Twin Ectopic Pregnancy. A Case Report. Primary ovarian pregnancy is a rare form of ectopic gestation and one that is often diagnosed only at the time of surgery.A 17-year-old primi- gravid woman presented to our clinic with lower abdom- inal pain, vaginal bleeding, and missed period. Trans- vaginal sonography revealed an empty uterus, normal- looking right fallopian tubes, and the presence of a gestational sac containing 2 yolk sacs and 2 embryos with cardiac (...) activity on the right ovary. Methotrexate therapy failed and the patient was successfully treated with laparoscopic enucleation of the ectopic pregnancy mass.Surgery is the primary treatment modality of choice in twin ovarian pregnancy. Therefore, the differential diagnosis of ovarian pregnancy is of great importance in order to plan immediate surgery and save the patient from unnecessary medical treatment, and thus preserving future fertility.

2016 Journal of Reproductive Medicine

191. Acute pelvic pain in female with ruptured ectopic pregnancy: Magnetic Resonance Imaging as problem solving tool Full Text available with Trip Pro

Acute pelvic pain in female with ruptured ectopic pregnancy: Magnetic Resonance Imaging as problem solving tool 27896332 2018 11 13 2452-2473 16 2 2016 Jun Turkish journal of emergency medicine Turk J Emerg Med Acute pelvic pain in female with ruptured ectopic pregnancy: Magnetic Resonance Imaging as problem solving tool. 89-90 Indiran Venkatraman V Department of Radiodiagnosis, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India. eng Journal Article 2016 05 08 Turkey Turk J

2016 Turkish journal of emergency medicine

192. Trends in ectopic pregnancy, hydatidiform mole and miscarriage in the largest obstetrics and gynaecology hospital in China from 2003 to 2013 Full Text available with Trip Pro

Trends in ectopic pregnancy, hydatidiform mole and miscarriage in the largest obstetrics and gynaecology hospital in China from 2003 to 2013 Ectopic pregnancies, miscarriages and hydatidiform moles are the major types of pathological pregnancies in the early gestations of pregnancy and constitute an important public health problem. The trends and incidences of these pathological pregnancies may vary by ethnicity and geographical regions. This has not been fully investigated in the Chinese (...) population. In this study we retrospectively report the trends of pathological pregnancies in Chinese population.Data on 22,511 women with ectopic pregnancy, hydatidiform mole and miscarriage were collected from the largest obstetrics and gynaecology hospital in China from 2003 to 2013. Data included age at diagnosis and the annual number of women with diagnosed ectopic pregnancy, hydatidiform mole and miscarriage.The total number of ectopic pregnancy, hydatidiform mole and miscarriage was increased

2016 Reproductive health

193. Association between knowledge about levonorgestrel emergency contraception and the risk of ectopic pregnancy following levonorgestrel emergency contraception failure: a comparative survey Full Text available with Trip Pro

Association between knowledge about levonorgestrel emergency contraception and the risk of ectopic pregnancy following levonorgestrel emergency contraception failure: a comparative survey To study the association between knowledge about levonorgestrel emergency contraception (LNG-EC) and the risk of ectopic pregnancy (EP) following LNG-EC failure.This study included 600 women who had visited the hospital with LNG-EC failure. Of these, 300 with EP and 300 with intrauterine pregnancy (IUP) were

2016 Pharmacoepidemiology and drug safety

194. Ectopic pregnancy in simultaneous pancreas-kidney transplantation: A case report Full Text available with Trip Pro

Ectopic pregnancy in simultaneous pancreas-kidney transplantation: A case report We present a case report of ectopic pregnancy (EP) after simultaneous pancreas-kidney transplantation (SKPTx).A 33-year-old female status post SKPTx suddenly got abdominal pain in the lower level. She had high human chorionic Gonadotropin test. Ultrasonography revealed that there was no fetus in the uterus but a dilated right fallopian tube, which strongly suggested ectopic pregnancy. An emergency operation (...) was performed and a dilated right side uterine tube was found with adhesions to her transplant. Salpingectomy was performed and no visible injury to the pancreas was found by the procedure. Pathological evaluation showed ectopic pregnant fetus, and no pancreas dysfunction was observed after the operation.This is the first case and operation report of EP after SKPTx. We should consider various causes of acute abdomen as well as several pathological condition in the transplanted pancreas such as pancreatitis

2016 International journal of surgery case reports

195. Not All Acute Abdomen Cases in Early Pregnancy Are Ectopic; Expect the Unexpected: Renal Angiomyolipoma Causing Massive Retroperitoneal Haemorrhage Full Text available with Trip Pro

, flank, abdominal, or back pain, or haemodynamic instability of unclear cause. Our patient presented with features of acute abdomen and, being pregnant, was thought of having a ruptured ectopic pregnancy. (...) Not All Acute Abdomen Cases in Early Pregnancy Are Ectopic; Expect the Unexpected: Renal Angiomyolipoma Causing Massive Retroperitoneal Haemorrhage Retroperitoneal haemorrhage (or retroperitoneal haematoma) refers to an accumulation of blood found in the retroperitoneal space. It is a rare clinical entity with variable aetiology including anticoagulation, ruptured aortic aneurysm, acute pancreatitis, malignancy, and bleeding from renal aneurysm. Diagnosis of retroperitoneal bleed is sometimes

2016 Case reports in critical care

196. The Role of Serum Beta hCG in Early Diagnosis and Management Strategy of Ectopic Pregnancy Full Text available with Trip Pro

The Role of Serum Beta hCG in Early Diagnosis and Management Strategy of Ectopic Pregnancy The presentation of Ectopic Pregnancy (EP) can be highly variable and serum Beta hCG estimation plays an important role in early diagnosis.Aim of the study was to determine the trends of hCG levels in EP and to explore the role of hCG in decisions related to management and follow-up of EPs.A retrospective study of women who had EPs from January 2006 to December 2012 at an advanced tertiary care centre (...) % of these women, there was a rise >53% similar to intrauterine pregnancy. The average pre-treatment Beta hCG was 429.8, 3866.2 and 12961.5 mIU/ml for those who received expectant, medical and direct surgical treatment respectively. 43 women with relative contraindications received medical management and 39 were lost to follow-up after medical and expectant management. Excluding them, the success rate of these two modalities was 76.6% and 85.0% respectively.No single level of Beta hCG is diagnostic of EP

2016 Journal of clinical and diagnostic research : JCDR

197. Clinical Analysis of Ectopic Pregnancies in a Tertiary Care Centre in Southern India: A Six-Year Retrospective Study Full Text available with Trip Pro

Clinical Analysis of Ectopic Pregnancies in a Tertiary Care Centre in Southern India: A Six-Year Retrospective Study Ectopic Pregnancy (EP) is a life-threatening emergency commonly encountered by medical practitioners where diagnosis can often be missed. Any woman in the reproductive age group, presenting with lower abdominal pain or vaginal bleeding must raise the suspicion of an ectopic pregnancy to prevent mortality and morbidity.To review all cases of EP and determine the incidence of EP (...) %) and pelvic surgery (37.50%). Fifteen cases (20.8%) were diagnosed in women who had tubectomy. The classic triad of lower abdominal pain, amenorrhoea and vaginal bleeding was seen in 29(40.3%) cases. Ultrasonography was required to arrive at a diagnosis in 28(38.9%) cases. Urine pregnancy test was positive in 100% of cases. Majority (94.4%) were tubal ectopic pregnancies. Medical management with methotrexate alone benefitted 10(13.89%) of patients while another four required surgery for failed medical

2016 Journal of clinical and diagnostic research : JCDR

198. Serum concentration of vascular endothelial growth factor and depth of trophoblastic invasion in ampullary ectopic pregnancy Full Text available with Trip Pro

Serum concentration of vascular endothelial growth factor and depth of trophoblastic invasion in ampullary ectopic pregnancy To evaluate the association between the depth of trophoblastic infiltration and serum vascular endothelial growth factorconcentration in patients with an ampullary pregnancy.This prospective cross-sectionalstudy involved 34 patients with an ampullary ectopic pregnancy who underwent salpingectomy between 2012 and 2013. Maternal serum vascular endothelial growth factor (...) factor concentration of 25.9 pg/mL best differentiated stage I from stages II and III with asensitivity of 75.0%, specificity of 76.9%, and area under the curve of 0.798.The depth of trophoblastic penetration into the tubal wall isassociated with serum vascular endothelial growth factor concentration in ampullary pregnancies.

2016 Clinics

199. Case Report of Ectopic Ovarian Pregnancy Following Fresh Embryo Transfer Full Text available with Trip Pro

Case Report of Ectopic Ovarian Pregnancy Following Fresh Embryo Transfer Ovarian pregnancy is a rare and challenging clinical phenomenon. Recent studies have identified assisted reproductive treatments and infertility as risk factors. However, neither a definite mechanism nor clear risk factors were identified and therefore prevention strategies are yet unavailable.In this article, we present a case of ovarian pregnancy occurring following in vitro fertilization treatment and a fresh embryo (...) transfer. The couple was diagnosed with unexplained infertility and no identifiable risk factors for extrauterine pregnancy. The diagnosis of ovarian pregnancy was made during explorative laparoscopy performed due to suspected extrauterine pregnancy. The patient had normal intra- and postoperative course.Ovarian pregnancy is an infrequent and a challenging diagnosis. Yet, late diagnosis and lack of appropriate intervention may have long-term implications. Several mechanisms and risk factors

2016 Clinical medicine insights. Reproductive health

200. Laparoscopic tube-preserving surgical procedures for ectopic tubal pregnancy Full Text available with Trip Pro

Laparoscopic tube-preserving surgical procedures for ectopic tubal pregnancy To present our experience with laparoscopic tube-preserving surgery for ectopic tubal pregnancy and evaluate its feasibility and efficacy.This was a prospective study of 57 consecutive patients with ectopic tubal pregnancies undergoing laparoscopic tube-preserving procedures including salpingotomy, salpingostomy, segmental resection and reanastomosis, and fimbrial milking. The outcome measures were treatment success (...) gonadotropin resolution time of 18.3±5.9 days, no persistent trophoblast or postoperative complications occurred. A tubal patency test using hysterosalpingography was performed in 15 cases at 3 months postoperatively. Among these, the homolateral tubal patency rate was 75% (11 of 15) and the contralateral patency rate was 80% (12 of 15).Tube-preserving surgery is a feasible and safe treatment option for ectopic tubal pregnancy. However, considering that the optimal goal of tube-preserving surgical

2016 Obstetrics & gynecology science

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