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161. Identifying How Area-based Socio-economic Indicators are Measured in Canada

. Zandy M, Li, Zhang R, Kao D, Fahra R, Turcotte K. Area-based socioeconomic disparities in mortality due to unintentional injeury and youth suicide in British Columbia, 2009-2013. Policy and Practice 2019;39(2): 2009-13. 6. Allin S, Pichora E, Perumal N, Jin J, Catley C, Polsky J. Comparing individual and area-based income measures: Impact on analysis of inequality in smoking, obesity, and diabetes rates in Canadian 2003- 2013. Canadian Journal of Public Health 2018;109(3): 410-8. 7. Matheson F, Dunn (...) M, Partridge M. Low-income dynamics in Canadian communities: A place-based approach. Growth and Change 2009;2008(39): 2. 13. Webb S, Janus M, Duku E, Raos R, Brownell M, Forer B. Neighbourhood socioeconomic status indices and early childhood development. Population Health 2017;3: 48-56. 14. Hanley G, Morgan S. On the validity of area-based income measures to proxy household income. BMC Health Services Research 2008;8: 1-7. 15. Schuunerman N, Bell N, Dunn J, Oliver L. Deprivation indices

2019 McMaster Health Forum

162. Learning from the Experience of Accountable Care Organizations in the U.S.

that of accountable care organizations in the U.S., which were formally implemented as part of the changes to the U.S. Patient Protection and Affordable Care Act, with the goals of linking payment for healthcare to quality outcomes, encouraging integrated health systems, reducing the cost of care and administration, and understanding and addressing health disparities. • Given these similarities between OHTs at maturity and ACOs in the U.S., we examined the design, evolution and effects of U.S. ACOs to identify (...) ; and • benchmarking the quality of care according to a set of key indicators.(3) As OHTs develop, they can build on what has gone well with ACOs and improve on what has gone less well. For example, ACOs’ effects on the quadruple aim can give insights into where OHTs may need to pay particular attention in order to achieve desired effectives. Given the learning potential, we sought to examine the design, development, evolution and effects of U.S. accountable care organizations. To do so, we have updated a rapid

2019 McMaster Health Forum

163. Empowering Caregivers to Deliver Home-based Restorative Care

) Two reviews focused on communications training provided to both health professionals and caregivers, finding mixed effects between the two reviews with one reporting improved knowledge and competency while the other found no significant post-training improvement on behavioural challenges, but some reduction in caregiving anxiety and depression.(28; 29) Finally, one study included in a recent medium-quality review examined the impact of calendars and note-taking among caregivers of those with mild (...) meaningful activities, and making environmental adaptations.(31) Another older medium-quality review found that modifications to physical and emotional factors or to lifestyle adaptations can be supported through the use of family-based education that includes the caregiver and care recipient.(32) Apart from the findings related to knowledge, skills, attitudes and behaviours, a significant portion of the evidence found in the systematic reviews examined the effectiveness of different modes

2019 McMaster Health Forum

164. Exploring Models for Health Workforce Planning

or not enough needs? Refocusing health workforce planning from providers and services to populations and needs. Journal of Health Services Research & Policy 2013; 18(2): 107-113. 12. Guttmann A, Cohen E, Moore C. Outcomes-based health human resource planning for maternal, child and youth health care in Canada: A new horizon for the 21st century. Paediatric Child Health 2009; 14(5): 310-4. 13. Van Greuningen M, Batenburg RS, Van der Velden LF. Ten years of health workforce planning in the Netherlands (...) of policy reforms, new models of care, changes in labour markets). • This rapid synthesis examines the health workforce planning models in place across select Canadian provinces and comparator jurisdictions to determine what models, processes and characteristics are important to establishing successful predictive models. What we found • We identified three systematic reviews and nine primary studies that related to the questions and complemented these findings with insights from interviews with 11 key

2019 McMaster Health Forum

165. Extended Stay Centers: Patient characteristics and appropriate procedures

. Journal of Spinal Disorders & Techniques, 26(6), 298-304. doi: 10.1097/BSD.0b013e318246aea2 Voyles, C. R., & Boyd, K. B. (1999). Criteria and benchmarks for laparoscopic cholecystectomy in a free- standing ambulatory center. JSLS, 3(4), 315-318. 26 ¦ Ambulatory Surgery Centers with Extended Stay Centers: Appropriate Procedures and Patient Characteristics Approved 5/16/2019 Watkins, B. M., Ahroni, J. H., Michaelson, R., Montgomery, K. F., Abrams, R. E., Erlitz, M. D., & Scurlock, J. E. (2008 (...) ., Lombardi, A. V., Jr., Berend, M. E., Adams, J. B., & Morris, M. J. (2018). The outpatient total hip arthroplasty: A paradigm change. Bone Joint Journal, 100-b(1 Supple A), 31-35. doi: 10.1302/0301-620x.100b1.bjj-2017-0514.r1 Berend, M. E., Lackey, W. G., & Carter, J. L. (2018). Outpatient-focused joint arthroplasty is the future: The Midwest Center for Joint Replacement experience. Journal of Arthroplasty, 33(6), 1647- 1648. doi: 10.1016/j.arth.2018.02.002 Billing, P., Billing, J., Kaufman, J., Stewart

2019 Oregon Health Evidence Review Commission

166. Pregnancy and Renal Disease

collection: gold standard or historical practice? Am J Obstet Gynecol. 2008; 199:625.e1-6. 4. Methven S, MacGregor MS, Traynor JP et al. Assessing proteinuria in chronic kidney disease: protein- creatinine ratio versus albumin-creatinine ratio. Nephrol Dial Transplant. 2010; 25:2991-2996. 5. Côté A-M, Brown MA, Lam E et al. Diagnostic accuracy of urinary spot protein:creatinine ratio for proteinuria in hypertensive pregnant women: systematic review. BMJ. 2008; 336:1003-1006. Renal Association Clinical (...) the Chair of the Clinical Practice Guidelines Committee. If no agreement had been reached on the appropriate grading of a recommendation, a vote would have been held and the majority opinion was carried. However, this was not necessary for this guideline. The level of agreement with the first draft of recommendations was examined via a modified Delphi process. An electronic survey of the authors’ recommendation was circulated nationally to members of the UK Renal Association and to obstetric medicine

2019 Renal Association

167. Learning Resilience

Learning Resilience Supporting evidence for the Be You Professional Learning Learning Resilience domain This review has been developed to support the Learning Resilience domain of Be You Professional Learning. It provides an overview of the research and evidence underpinning each of the learning modules and allows you to further engage with the key themes and advice. The review provides an overview of the research examining the relationship between social and emotional learning skills (...) who live and work in a particular society, enabling that society to function effectively. Social competence The ability to handle social interactions effectively. Somatic complaints Unexplained symptoms of illness. Value affirmation Involves identifying what is important to the person and then engaging in behaviours in line with those values. Learning Resilience: Supporting evidence 4 Executive summary Background This review examined the latest evidence on the relationship between social

2019 Sax Institute Evidence Check

168. Addressing the social and commercial determinants of healthy weight

and obesity. 7 ADDRESSING THE SOCIAL AND COMMERCIAL DETERMINANTS OF HEALTHY WEIGHT | SAX INSTITUTE In question 2, studies were included if they examined the effectiveness of interventions related the social and commercial determinants of obesity. The evidence was supplemented with a targeted search of the primary literature, plus evidence from authoritative reports relevant to obesity prevention in Australia. Key findings Question 1: Associations Thirty-two review level studies met the inclusion criteria (...) . Studies that met the following general and review question specific criteria were included: General • Published from 2010 to the end of June 2019 • Published in English language • Had a majority of included studies conducted in Australia or comparable countries (e.g. Canada, NZ, the UK, USA). Review question 1 • Examined a social or commercial determinant other than the food environment or food system (these determinants were examined in the Sacks et al. review) • Reported on the relationship

2019 Sax Institute Evidence Check

169. Family Partnerships

. Suggested citation: Clancy E., Benstead M., Little K., Skvarc D., Westrupp E., Yap M., Havighurst, S., & Toumbourou J.W. Family Partnerships to Support Children and Young People's Mental Health: an Evidence Check rapid review brokered by the Sax Institute ( for Be You, 2019. Family Partnerships: Supporting evidence 3 Contents Glossary 4 Executive summary 6 Background 10 Methods 14 Peer-reviewed literature 14 Grey literature 14 Findings 15 Discussion 20 Conclusion 25 References 26 (...) in activities such as playgroups and parent home reading. The present review examined whether family-educator partnership interventions can also reduce mental health problems in children and young people. Summary of methods To identify peer-refereed review papers of interventions with the primary aim of preventing mental health problems or promoting mental health and wellbeing, keyword and subject headings were searched on 29 April 2019. Six literature reviews were identified that met the inclusion criteria

2019 Sax Institute Evidence Check

170. Responding Together

. Psychiatry. 2002;65(3):207-39. 19. Madrid PA, Grant R, Reilly MJ, Redlener N. Short-term impact of a major disaster on children’s mental health: Building resiliency in the aftermath of Hurricane Katrina. Pediatrics. 2006;117(5):S448-S53. 20. Gibbs L, Nursey J, Cook J, Ireton G, Alkemade N, Roberts M, et al. Delayed disaster impacts on academic performance of primary school children. Child Dev. 2019;90(4):1402–12. 21. Berger E, Carroll M, Maybery D, Harrison D. Disaster impacts on students and staff from (...) . Suggested citation: Sartore G-M. Macvean M. Devine B. Shackleton F. Responding Together to Critical Incidents: an Evidence Check rapid review brokered by the Sax Institute ( for Beyond Blue, 2019 Responding Together: Supporting evidence 3 Contents Executive summary 4 Background 6 Aims 9 Methods 9 Findings 9 Discussion 16 Conclusion 18 References 19 Appendices 22 Appendix 1. Methods 22 Appendix 2. Findings 27 Responding Together: Supporting evidence 4 Executive summary Background

2019 Sax Institute Evidence Check

171. Mentally Healthy Communities

been developed. Specifically looks at the key attributes of a mentally healthy learning community, as well as the strategies that have been shown to be effective in contributing to positive mental health and wellbeing in children and young people within early learning and school settings. Educators will best engage with this review if read in conjunction with the Professional Learning modules in the Mentally Healthy Communities domain. Suggested citation: Hoare E. Mentally Healthy Communities (...) mental health support. • Supporting the physical health of children and young people can provide benefits for mental health. Aligning efforts to achieve both physical and mental health goals can be a pragmatic use of resources, and improved health behaviours have been associated with improved mental health outcomes. Mentally Healthy Communities: Supporting evidence 7 Gaps in the evidence There was limited evidence examining the key attributes and effective strategies for mental health and wellbeing

2019 Sax Institute Evidence Check

172. Population-level strategies to support healthy weight

Institute Phone: +61 2 91889500 Suggested Citation: Sacks G, Looi E, Cameron A, Backholer K, Strugnell C et al. Population-level strategies to support healthy weight: an Evidence Check rapid review brokered by the Sax Institute ( for Queensland Health, 2019. Disclaimer: This Evidence Check review was produced using the Evidence Check methodology in response to specific questions from the commissioning agency (...) Check, the research team developed a search strategy to assess the latest evidence to supplement and refine the recommendations from the WHO ECHO report, add in consideration of evidence related to adults (the WHO ECHO report focused on childhood obesity), and tailor the global recommendations to the Australian context. We included studies that were systematic reviews and/or meta- analyses (the highest standard of evidence) published between January 2016 and June 2019 that examined the effectiveness

2019 Sax Institute Evidence Check

173. Early Support

to provide appropriate support is key to preventing more serious mental health outcomes down the track. This review looks at the programs and strategies which have been shown to be effective in improving mental health literacy in educators to assist them in identifying and responding to early signs of mental health issues. Educators will best engage with this review if read in conjunction with the Professional Learning modules in the Early Support domain. Suggested citation: Berger E. Reupert A. Allen K (...) of children and youth • providing predictability and routines for children and young people • providing academic choice and self-directed learning for children and young people. Gaps in the evidence Although there are many PD programs for educators, few of these measure outcomes for children and young people. As a result, only 30 studies (and 25 PD programs) were included in the current review. Most studies examined self-perceived changes in educator knowledge, confidence and skills, as opposed

2019 Sax Institute Evidence Check

174. Acute Kidney Injury (AKI)

manual. Nephron Clin Pract 2011, 118 Suppl 1:c13-25. Renal Association Clinical Practice Guideline Acute Kidney Injury (AKI) - August 2019 6 2. Summary of clinical practice guidelines 1. Definition, Epidemiology and Outcomes Guideline 1.1 - Adults and Paediatrics We recommend that the Kidney Disease: Improving Global Outcomes (KDIGO) system for the diagnosis and staging of AKI should be adopted; serum creatinine-based criteria should be applied according to the current NHS England biochemical (...) . Clinical Assessment History, Examination Guideline 3.1 – Adults and Paediatrics (unless otherwise stated) We recommend that: ? all patients with AKI have an appropriate history and examination performed to help determine the cause of the episode of AKI. (1D) Renal Association Clinical Practice Guideline Acute Kidney Injury (AKI) - August 2019 7 ? adults only: all patients with progressive AKI should be re-assessed, particularly if the course is atypical (1D) ? paediatrics only: all patients

2019 Renal Association

175. Heritable mutations associated with familial hypercholesterolaemia - Clinical Utility Card application

utility card (CUC). 2. MSAC’s advice to the Minister After considering the strength of the available evidence in relation to comparative safety, clinical effectiveness and cost-effectiveness, MSAC supported MBS listing of genetic testing for heritable mutations associated with familial hypercholesterolaemia in affected individuals meeting defined eligibility criteria, and targeted cascade testing in first and second-degree relatives of those affected individuals with a confirmed genetic diagnosis (...) of the requirements for access to PCSK9 inhibitors (evolocumab) on the Pharmaceutical Benefits Scheme (PBS). Evolocumab was listed on the PBS in March 2016 for homozygous FH patients and in March 2018 for heterozygous FH patients. MSAC considered that likely earlier subsidised access to this therapy for family members testing positive to cascade testing was the main source of expected clinical utility, but noted that this was not included in the assessment. MSAC queried whether the PBS criteria would lead

2019 Medical Services Advisory Committee

176. Upadacitinib (Rinvoq) - rheumatoid arthritis

. Reference ID: 4476845Clinical Review Keith M Hull, MD, PhD NDA 211675 RINVOQ (upadacitinib) Major inclusion criteria: ? Male and female subjects =18 years-of-age ? Diagnosis of RA based on the 2010 ACR/EULAR criteria for a duration for =3 months ? =6 swollen joints (based on 66 joint counts) ? =6 tender joints (based on 68 joint counts) ? hsCRP =5 mg/L ? =1 bone erosion on x-ray OR RF (+) and anti-CCP (+) ? Have been naïve to MTX therapy Major exclusion criteria: ? Prior exposure to any JAK inhibitor (...) ? Prior exposure to any bDMARD ? History of an inflammatory joint disease other than RA ? Laboratory values meeting the following criteria o AST or ALT >2 x ULN o eGFR 20% improvement from baseline in both tender joint count and swollen joint count. Updated text to clarify Independent Joint Assessor. Updated text to clarify TB assessment and testing. Added text that all subjects to have ECG performed at screening and every 48 weeks. Reference ID: 4476845Clinical Review Keith M Hull, MD, PhD NDA 211675

2019 FDA - Drug Approval Package

177. Ovarian Stimulation for IVF/ICSI


2019 European Society of Human Reproduction and Embryology

178. Istradefylline (Nourianz) - Parkinson's disease

(kg/m 2 ) Mean (SD) 28.5 (5.2) 25.6 (5.1) 25.6 (5.4) 26.3 (4.6) 25.6 (4.9) 25.8 (5.1) Median 28 25 24.9 25.9 25.5 25.2 Min, Max 18.5, 47.4 15.3, 54.4 13.8, 57.2 15.9, 41.8 14.5, 46.9 13.8, 57.2 This table was created by the reviewer using the ISS dataset ADSL. Pool S1 was similar to Pool 1 except that there was a higher percentage of females in Pool S1 (49%), a higher percentage of Asians (55%) and a higher incidence of studies occurring outside CDER Clinical Review Template Version date (...) N=1893 % (n) Native Hawaiian or other Pacific Islander 0 0.1 (2) 0 0.1 (2) Other 0 0.3 (4) 0.3 (1) 0.3 (5) White 0 73 (1096) 93.1 (309) 74.2 (1405) Region North America 0 58.8 (883) 100 (332) 64.2 (1215) Outside of North America 100 (60) 41.2 (618) 0 35.8 (678) BMI (kg/m 2 ) Mean (SD) 22.3 (3.3) 26.2 (5.2) 26.5 (4.8) 26.1 (5.1) Median 22.4 25.6 26.0 25.6 Min, Max 15.9, 33.4 14.2, 54.4 15.9, 57.2 14.2, 57.2 This table was created by the reviewer using the ISS dataset ADSL. The following table

2019 FDA - Drug Approval Package

179. Sexualized drug use (chemsex and methamphetamine) and men who have sex with men

with men who use methamphetamine: A systematic review. Drug & Alcohol Dependence. 2019;194:410–29. Bryant J, Hopwood M, Dowsett GW, Aggleton P, Holt M, Lea T, et al. The rush to risk when interrogating the relationship between methamphetamine use and sexual practice among gay and bisexual men. International Journal of Drug Policy. 2018;55:242–8. Hopwood M, Cama E, Treloar C. Methamphetamine use among men who have sex with men in Australia: A literature review. 2016. Available from: Accessed April 23 (...) , 2019. Bourne A, Weatherburn P. Substance use among men who have sex with men: Patterns, motivations, impacts and intervention development need. Sexually Transmitted Infections. 2017;93(5):342–6. Edmundson C, Heinsbroek E, Glass R, Hope V, Mohammed H, White M, et al. Sexualised drug use in the United Kingdom (UK): A review of the literature. International Journal of Drug Policy. 2018;55:131–48. Melendez-Torres GJ, Bourne A. Illicit drug use and its association with sexual risk behaviour among MSM

2019 Ontario HIV Treatment Network

180. Digital platforms as effective health promotion tools

, PsycINFO, Scopus and ProQuest databases to identify studies that conducted user testing of digital platforms with parents (Q2) and evaluated the effectiveness of digital platforms targeting parents (Q3). We included studies if they were published in English, published from 2008 (Q2) or from 2013 (Q3) and conducted in Australia or other specified countries of interest. The quality of included studies was evaluated against the NHMRC evidence grade. Thirty studies met the criteria for inclusion (...) enabling personalisation and interactivity that were desired in user testing. However, evaluating the website in its current form to determine its effectiveness would inform whether additional improvements were required. There is a gap in the market for evidence-based apps to support parental lunch-box provision, which is worth examining as a potential opportunity. Conclusion The Evidence Check demonstrated that digital health promotion tools targeting parents can be effective for improving dietary

2019 Sax Institute Evidence Check

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