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121. Chronic obstructive pulmonary disease in over 16s: diagnosis and management

Chronic obstructive pulmonary disease in over 16s: diagnosis and management Chronic obstructiv Chronic obstructive pulmonary disease in e pulmonary disease in o ov ver 16s: diagnosis and management er 16s: diagnosis and management NICE guideline Published: 5 December 2018 © NICE 2019. All rights reserved. Subject to Notice of rights ( rights).Y Y our responsibility our responsibility The recommendations (...) is purely arbitrary response to long-term therapy is not predicted by acute reversibility testing. [2004] [2004] 1.1.19 Untreated COPD and asthma are frequently distinguishable on the basis of history (and examination) in people presenting for the first time. Whenever possible, use features from the history and examination (such as those listed in table 3) to differentiate COPD from asthma. For more information on diagnosing asthma, see the NICE guideline on asthma. [2004, amended 2018] [2004, amended

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

122. Chronic heart failure in adults: diagnosis and management

services if needed. [2018] [2018] Care after an acute e Care after an acute ev vent ent For recommendations on the diagnosis and management of acute heart failure see NICE's guideline on acute heart failure. 1.1.5 People with heart failure should generally be discharged from hospital only when their clinical condition is stable and the management plan is optimised. Timing of discharge should take into account the wishes of the person and their family or carer, and the level of care and support that can (...) if appropriate, and all health and social care professionals involved in their care. [2018] [2018] 1.2 Diagnosing heart failure Symptoms, signs and in Symptoms, signs and inv vestigations estigations 1.2.1 T ake a careful and detailed history, and perform a clinical examination and tests to confirm the presence of heart failure. [2010] [2010] 1.2.2 Measure N-terminal pro-B-type natriuretic peptide (NT-proBNP) in people with suspected heart failure. [2018] [2018] Chronic heart failure in adults: diagnosis

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

123. Age-related macular degeneration

techniques with their family members or carers (as appropriate). Monitoring for late AMD (wet activ Monitoring for late AMD (wet active e) ) 1.7.8 Offer people with late AMD (wet active) ongoing monitoring with OCT for both eyes. 1.7.9 Offer fundus examination or colour photography if OCT appearances are stable, but: there is a decline in visual acuity or or the person reports a decline in visual function. 1.7.10 Consider FFA to identify unrecognised neovascularisation if OCT appearances are stable (...) (AREDS 2001) examined the effect of antioxidant supplementation on AMD progression using the AREDS formation, which included beta carotene, vitamin E, vitamin C and zinc. Although the study showed some beneficial effects of the combined antioxidant supplementation in a subgroup of participants, the effects of each of the formula components on AMD progression were unclear. Additionally, 1 of the ingredients (beta carotene) in the AREDS 2001 formulation is associated with a possible risk of lung cancer

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

124. Daratumumab with bortezomib and dexamethasone for previously treated multiple myeloma

Daratumumab with bortezomib and dexamethasone for previously treated multiple myeloma Dar Daratumumab with bortezomib and atumumab with bortezomib and de dexamethasone for pre xamethasone for previously treated viously treated multiple m multiple my yeloma eloma T echnology appraisal guidance Published: 10 April 2019 © NICE 2019. All rights reserved. Subject to Notice of rights ( rights).Y Y our responsibility our (...) received at least one prior therapy' . Dosage in Dosage in the the mark marketing eting authorisation authorisation Daratumumab 16 mg/kg body weight is administered by intravenous infusion every week for weeks 1 to 9, every 3 weeks for weeks 10 to 24 and every 4 weeks from week 25 onwards. Bortezomib is administered by subcutaneous injection at a dose of 1.3 mg/m 2 twice weekly on days 1, 4, 8 and 11 for 8×21-day cycles. Dexamethasone is administered orally at a dose of 80 mg weekly. Price Price

2019 National Institute for Health and Clinical Excellence - Technology Appraisals

125. Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy

the benefits and harms of different screening tests for their individual situation. Faecal testing with a faecal immunochemical test (FIT) every year Faecal testing with a faecal immunochemical test (FIT) every two years Endoscopic examination of only the lower part of the colon Endoscopic examination of the entire colon Favours no screening Favours screening Colonoscopy offered if FIT or sigmoidoscopy positive People with an estimated 15 year risk of colorectal cancer below 3% We suggest screening (...) risk. For the full disclaimer wording see BMJ's terms and conditions: Lise M Helsingen , methods co-chair, medical doctor , Per Olav Vandvik , general internist, methodologist , Henriette C Jodal , medical doctor , Thomas Agoritsas , general internist, methodologist , Lyubov Lytvyn , patient partnership liaison , Joseph C Anderson , gastroenterologist , Reto Auer , general practicioner , Silje Bjerkelund Murphy , registered nurse , Majid Abdulrahman Almadi , gastroenterologist , Douglas A Corley

2019 BMJ Rapid Recommendations

126. Subacromial decompression surgery for adults with shoulder pain

workers . van der Windt DA , Thomas E , Pope DP , et al . Occupational risk factors for shoulder pain: a systematic review . Hermans J , Luime JJ , Meuffels DE , Reijman M , Simel DL , Bierma-Zeinstra SM . Does this patient with shoulder pain have rotator cuff disease?: The Rational Clinical Examination systematic review . Whittle S , Buchbinder R . In the clinic. Rotator cuff disease . Brox JI . Regional musculoskeletal conditions: shoulder pain . Gill TK , Shanahan EM , Allison D , Alcorn D , Hill (...) of practical issues related to the decision to have surgery and met all authorship criteria for the present article. We thank them for their time and contribution. Footnotes This BMJ Rapid Recommendation article is one of a series that provides clinicians with trustworthy recommendations for potentially practice changing evidence. BMJ Rapid Recommendations represent a collaborative effort between the MAGIC group ( ) and The BMJ . A summary is offered here and the full version including decision aids

2019 BMJ Rapid Recommendations

127. The Japanese Hypertension Guidelines

r e c o m m e n d s t o s t a r t antihypertensive drug treatment with adults aged under 80 with mild hypertension (Stage 1) who has damage in the target organ (risk factor for cardiovascular disease). However, in those with mild hypertension who has no risk factor, there is no evidence to prove benefit of antihypertensive drug treatment. The Cochrane review [6] evaluated 4 randomized controlled trials for antihypertensive drug treatment in patients with mild hypertension (systolic BP 140-159 (...) The Japanese Hypertension Guidelines Page 36 · MED CHECK December 2019/ Vol.5 No.15 C N o 15 M ED HECK 2 0 1 9 Problems in Selection of Members for Guidelines Hypertension Guidelines Part 1, Part 2 Diovan Scandal High Risk of Death from Tamiflu and Xofluza Editorial The Japanese Hypertension Guidelines 2019 Problems in Selection of Members Review Critical Assessment of Hypertension Guidelines Part 1 Scientific evidence for the hypertension guidelines 2019 is poor Critical Assessment

2020 Med Check - The Informed Prescriber

128. Recommendations for good practice in Ultrasound: Oocyte retrieval

search navigation Article Navigation 2019 Article Contents Article Navigation Recommendations for good practice in ultrasound: oocyte pick up The ESHRE Working Group on Ultrasound in ART Search for other works by this author on: , Arianna D’Angelo Wales Fertility Institute , University Hospital of Wales, Cardiff University, Cardiff, UK Correspondence address. Wales Fertility Institute, University Hospital of Wales, Heath Park, Cardiff CF14 4XW, UK. E-mail: , Search for other works by this author (...) previous surgery (gynaecological surgery for myomas, endometriomas, adhesions). A basic diagnostic US examination also allows for the detection of recent lesions, such as endometrial abnormalities or ovarian cysts, in a timely manner. In addition, such transvaginal diagnostic US is of value to visualize not only the ovaries, but also the uterus and to check for potential difficulties during OPU. The accessibility of the ovaries and follicles and any potential complications or difficulties of the OPU

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2020 European Society of Human Reproduction and Embryology

129. What methods have been effective in promoting uptake of Pre-exposure prophylaxis (PrEP) among individuals at high risk of HIV, excluding men who have sex with men

attend planned parenthood. Journal of Acquired Immune Deficiency Syndromes 79(1) 46-53. Available: 11. Aaron E, Blum C, Seidman D, Hoyt MJ, Simone J, Sullivan M, et al. 2018. Optimizing delivery of HIV preexposure prophylaxis for women in the United States. AIDS Patient Care and STDs 32(1) 16-23. Available: 12. Farthing H, Rodriguez A, Armstrong M, Iyengar S, Nigh E, Potter J, et al. 2018 (...) 79(9-A(E)) No Pagination Specified. Available: 22. Ojikutu BO, Bogart LM, Mayer KH, Stopka TJ, Sullivan PS, Ransome Y 2019. Spatial Access and Willingness to Use Pre-Exposure Prophylaxis Among Black/African American Individuals in the United States: Cross-Sectional Survey. JMIR Public Health Surveill 5(1) e12405. Available: 23. Ojikutu BO, Bogart LM, Higgins-Biddle M, Dale SK, Allen W

2020 Publication 4890972

130. What research has been done to understand substance misuse within the UK student population, and what interventions have been introduced as a result?

-are-they- taking-them-96383]. 22. Dick S, Whelan E, M. D 2019. A systematic review of the effectiveness of digital interventions for illicit substance misuse harm reduction in third-level students. BMC Public Health []. 23. NUS 2018. NUS Alcohol Impact. []. 24. Holt M, Powell S 2017. Healthy Universities: a guiding framework for universities to examine the distinctive health needs of its own student population. Perspect Public (...) review identified 8 studies (2 from the UK) examining 6 digital interventions aimed at reducing harm from substance misuse in university/college What research has been done to understand substance misuse within the UK student population, and what interventions have been introduced as a result? KLS Evidence Briefing 31 st October 2019 students – most interventions produced at least one positive harm-reduction measure, with no negative effects, but the quality of the included studies was weak (22

2020 Publication 4890972

131. What is the current evidence for the efficacy of drug consumption rooms?

, Montaner JS, Kerr T. Reduction in overdose mortality after the opening of North America's first medically supervised safer injecting facility: A retrospective population-based study. The Lancet. 2011;377(9775):1429-37. 8. Kerr T, Tyndall M, Li K, Montaner J, Wood E. Safer injection facility use and syringe sharing in injection drug users. Lancet (London, England). 2005;366(9482):316-8. 9. Kimber J, Dolan K, Wodak A. Survey of drug consumption rooms: Service delivery and perceived public health (...) and amenity impact. Drug and Alcohol Review. 2005;24(1):21-4. 10. Boyd N. Lessons from INSITE, Vancouver's supervised injection facility: 2003-2012. Drugs: Education, Prevention & Policy. 2013;20(3):234-40. 11. Barry CL, Sherman SG, Stone E, Kennedy-Hendricks A, Niederdeppe J, Linden S, et al. Arguments supporting and opposing legalization of safe consumption sites in the U.S. International Journal of Drug Policy. 2019;63:18-22. 12. Milloy MJS, Kerr T, Tyndall M, Montaner J, Wood E. Estimated drug

2020 Publication 4890972

132. Raising the bar on strength and balance: The importance of community-based provision

assure sessions to support workforce and deliver in line with the evidence base Ensure health and safety, plus risk assessments including emergency plans, are in place Raising the bar | Centre for Ageing Better 7Instructors delivering strength and balance training Understand and respect the scope of practice that your training provides. Ensure that it is informed by evidence Provide clear inclusion criteria to referrers to support appropriate referrals Include conversations about goal setting (...) to attend in the locality but without imparting any information (about health status, medications, contraindications for exercise etc.) to the instructor. Referral A formally agreed system including inclusion and exclusion criteria and aligned with best practice referral processes. Strength and Balance Two components of fitness (there are others) that inform our capacity to be physically active i.e. reduced strength and balance will impact on our ability to perform activities of daily living. Uptake

2020 Publication 4890973

133. Employment support for over 50s: Rapid evidence review

-based actions? There is a very considerable evidence base on which to draw, although not all with relevance to place-based employment support for those unemployed or seeking to return to paid work. As an RER, the focus of this review is drawing on and critically reviewing past recently published evidence (2010 and since) and scoping available data. The inclusion criteria and search strategy to address the objectives were agreed with Ageing Better in September 2018 with a specific focus on evidence (...) Better 2019 2.1 Introduction The review was concerned to draw its findings and conclusions from reliable and potentially transferable sources. In practice, the robustness of identified evidence was variable and the quality of evidence (including data sources) we draw on in Chapters 3 and 4 is examined here for: - Its overall range and scope set against the review’s focus on place-based return to work support for over 50s in the UK 13 - The quality of that evidence – looking at the pedigree

2020 Publication 4890973

134. What approaches to performance management and performance appraisal in the workplace are effective for improving organisation outcomes or staff attitudes to the process?

development • Ensure managers involve employees in the appraisal discussions so that their voice can be heard • Check in with employees following appraisal to see how they are responding Feedback and goal orientation also seem to be gaining prominence within PA practice and research (6). A meta-analysis on the impact of PM on performance in public organisations examined 2,188 effects gathered from 49 studies (7). The study examined the effect of the “average” PM system, whether beneficial PM practices can (...) . Benchmarking appears to be an effective method for learning who is performing well – practitioners should emphasise the use of benchmarking over time to provide a valid comparison and replicate success (7). Four criteria for the effectiveness of PA systems have been suggested (8): • utilisation - why PAs are conducted (the reason for the existence of performance appraisals is rarely considered (9)) • qualitative - user’s justice perceptions and fairness of a PA system • quantitative – the psychometric

2020 Publication 4890972

135. Estimate of the economic costs and literature review of the benefits of dedicated research time for Hospital Consultants in the NHS

FP, Denduluri N, Kim ES. Critical aspects of a sustainable clinical research program in the community-based oncology practice. American Society of Clinical Oncology Educational Book. 39:176-184, 2019. Glover M, Montague E, Pollitt A, Guthrie S, Hanney S, Buxton M, Grant J. Estimating the Returns to United Kingdom Publicly Funded Musculoskeletal Disease Research in Terms of Net Value of Improved Health Outcomes. Health Research Policy and Systems. 16. 10.1186/s12961-017-0276-7. 2018. Grant J (...) , Buxton MJ. Economic returns to medical research funding. BMJ Open 2018;8:e022131 References Hiscock H, Ledgerwood K, Danchin M, Ekinci E, Johnson E, Wilson A. Clinical research potential in Victorian hospitals: the Victorian clinician researcher needs analysis survey. Internal Medicine Journal. 44(5): 477-82, 2014. Jonker L and Fisher SJ. The correlation between National Health Service trusts' clinical trial activity and both mortality rates and care quality commission ratings: a retrospective cross

2020 Academy of Medical Sciences

136. Kidney Pre-biopsy medication: Antiplatelet and anticoagulant agents

Pharmacology. 1995;35(3):209-19. 5. Garcia D, Libby E, Crowther MA. The new oral anticoagulants. Blood. 2010;115(1):15-20. 6. Biondi-Zoccai GG, Lotrionte M, Agostoni P, et al. A systematic review and meta-analysis on the hazards of discontinuing or not adhering to aspirin among 50 279 patients at risk for coronary artery disease. European heart journal. 2006;27(22):2667-74. 7. Burger W, CHEMNITIUS JM, Kneissl G, et al. Low -dose aspirin for secondary cardiovascular prevention –cardiovascular risks after (...) -centre retrospective study of 6,700 renal allograft biopsies performed in 2,362 patients between 2005 and 2014, Baffour et al.(18) examined the association between aspirin use and bleeding events. All biopsies were ultrasound guided and most were protocol biopsies (81.3%). The INR was less than 1.5 and platelet count greater than 50 x 10 9 /L in all patients. Three biopsy cores were obtained from each patient, using a needle size of =18 gauge. Aspirin doses were either 81mg or 325mg. Any bleeding

2020 KHA-CARI Guidelines

137. Routine Human Papilloma Virus (HPV) Testing in Squamous Cell Head and Neck Cancer

. Human papillomavirus in metastatic squamous carcinoma from unknown primaries in the head and neck: A retrospective 7 year study. Exper Molec Pathol. 2009;87(2):94-8. 7. El-Mofty SK, Zhang MQ, Davila RM. Histologic identification of human papillomavirus (HPV)-related squamous cell carcinoma in cervical lymph nodes: a reliable predictor of the site of an occult head and neck primary carcinoma. Head Neck Pathol. 2008;2(3):163-8. 8. Hoffmann M, Gottschlich S, Gorogh T, Lohrey C, Schwarz E, Ambrosch P (...) post-therapy; To define objective tumour response rates to induction chemotherapy and to subsequent radiation-based treatment, per RESIST version 1.1 criteria.; To assess progression- free survival at 2 years; To assess overall survival at 2 years.; To assess locoregional diseas e control at 2 years; To assess distant disease control at 2 years; Assessment of quality-of- life outcomes; To identify additional toxicity of treatment Phase III Trials: The Quarterback Trial: A Randomized Phase III

2020 Cancer Care Ontario

138. Effectiveness of mental health electronic medical records

solo practices to hospitals EMRs and RHR in general – not specified Not specified Also included use of EHR by people with mental illness Literature review – claims to use Cochrane Guidelines. Do not report number of studies identified; inclusion or exclusion criteria etc. Very poor reporting of review methodology Not specified Golberstein et al. (2018) USA Primary care clinics Mental health e-consult with psychiatry ordered by primary care Specific mental health questions asked by primary Primary (...) al. (32) did not provide any specific details, however, they included published papers that assessed any type of EMRs or EHRs including e-ordering of pathology, imaging and pharmacy. (32) They did not report on different aspects separately. Furthermore, although this review cites Cochrane methodology, they did not report the final number of papers identified for inclusion in the review and they did not report specific inclusion or exclusion criteria, nor did they provide a flowchart describing

2020 Sax Institute Evidence Check

139. Suicide postvention services

the same search string in the other databases using subject headings and keywords. The search was undertaken in April 2019, was not limited by language, and comprised the years 2014 to 2019. Two researchers (KA, KKr) independently assessed titles and abstracts for eligibility. We resolved any disagreement through discussion. Potentially relevant studies were examined against the inclusion and exclusion criteria. The references of retrieved papers and existing reviews were hand searched to identify (...) guidelines 71-82 met the inclusion criteria. We assessed the quality of the included studies with two instruments: the National Health and Medical Research Council (NHMRC) Levels of Evidence 56 and the Quality Assessment Tool for Quantitative Studies. 57 The guidelines were analysed based on the criteria provided in the Appraisal of Guidelines for Research and Evaluation II (AGREE) Instrument. 58 Evidence grading Based on NHMRC Level of evidence 56 , there were two level II studies, two level III-3

2020 Sax Institute Evidence Check

140. Suicide aftercare services

are promising but that a large-scale trial in a clinical population is needed before they would recommend wide roll-out. The remaining three systematic reviews provided narrative analysis only. Like Milner et al. 25 , Luxton 26 examined the effects of brief contact interventions (including letters, postcards, phone contact, visits or email) for people who had presented to hospital (ED or psychiatric units) for suicidal behaviour. Eleven publications met inclusion criteria for eight trials. Three of eleven (...) Suggested Citation: Shand F, Woodward A, McGill K, Larsen M, Torok M et al. Suicide aftercare services: an Evidence Check rapid review brokered by the Sax Institute ( for the NSW Ministry of Health, 2019. Disclaimer: This Evidence Check Review was produced using the Evidence Check methodology in response to specific questions from the commissioning agency. It is not necessarily a comprehensive review of all literature relating to the topic area. It was current at the time

2020 Sax Institute Evidence Check

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