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101. What helps to support people affected by Adverse Childhood Experiences? A Review of Evidence

of this report. Contributions The opinions expressed in this publication are not necessarily those of the EPPI-Centre or the funders. Responsibility for the views expressed remains solely with the authors. This report should be cited as: Lester S, Lorenc T, Sutcliffe K, Khatwa M, Stansfield C, Sowden A, Thomas J (2019) What helps to support people affected by Adverse Childhood Experiences? A Review of Evidence. London: EPPI-Centre, Social Science Research Unit, UCL Institute of Education, University College (...) synthesis 90 Studies not obtained in time (n=7) 90 Studies excluded on title and abstract (n=166) 90 Studies excluded on full text (n=34) 100 Studies excluded following quality and relevance appraisal (n=10) 102 Appendix E: Evidence tables for studies included in the views synthesis (n=21) 103 Appendix F: Results of Quality Appraisal (overview) 119 Appendix G: Evidence Tables (overview) 126 Appendix H: Lists of Excluded Studies (overview) 180 Studies excluded from the best-evidence synthesis on account

2019 EPPI Centre

102. Recovery schools for improving behavioral and academic outcomes among students in recovery from substance use disorders: a systematic review Full Text available with Trip Pro

Open Access Recovery schools for improving behavioral and academic outcomes among students in recovery from substance use disorders: a systematic review Corresponding Author E-mail address: Corresponding author Emily A. Hennessy Institute for Collaboration on Health Intervention & Policy University of Connecticut 2006 Hillside Road Storrs, CT, 06269 USA E‐mail: Corresponding Author E-mail address: Corresponding author Emily A. Hennessy Institute for Collaboration on Health Intervention & Policy (...) University of Connecticut 2006 Hillside Road Storrs, CT, 06269 USA E‐mail: First published: 04 October 2018 Linked article: . Give access Share full text access Please review our and check box below to share full-text version of article. I have read and accept the Wiley Online Library Terms and Conditions of Use. Shareable Link Use the link below to share a full-text version of this article with your friends and colleagues. Copy URL Share a link Share on ). Although not every youth who experiments

2018 Campbell Collaboration

103. Effectiveness of interventions to reduce homelessness: a systematic review and meta?analysis Full Text available with Trip Pro

and meta‐analysis Corresponding Author E-mail address: Corresponding author: Heather Menzies Munthe‐Kaas, Norwegian Institute of Public Health, Division for health services, PO Box 4404, Nydalen, N‐0403 Oslo, Norway, E‐mail: Corresponding Author E-mail address: Corresponding author: Heather Menzies Munthe‐Kaas, Norwegian Institute of Public Health, Division for health services, PO Box 4404, Nydalen, N‐0403 Oslo, Norway, E‐mail: First published: 28 February 2018 Give access Share full text access Please (...) combinations. Evaluations are typically based on comparison of one type of combination with another, or with “usual care” (often drop in centres, after care services, outpatient clinics, brokered case management, etc.). This means that housing programs are often not implemented and evaluated in similar forms. Any effort to analyse and synthesize evaluations of housings programs, case management and other included services, must therefore consider this complexity and lack of clarity. In addition

2018 Campbell Collaboration

104. Corticosteroids for treatment of sore throat Full Text available with Trip Pro

. Some patients with sore throat also experience headache, fever, muscle stiffness, cough, and general malaise. Acute sore throat is common, but only a minority of patients will visit their general practitioner. A survey reported that the main reasons are to establish the cause of the symptoms, obtain pain relief, and to gain information on the course of the disease. Data from Dutch and Flemish primary care databases show that, for every 1000 consecutive patients consulting a general practitioner, 50 (...) Guidelines Network. Management of sore throat and indications for tonsillectomy (SIGN 117). 2010. . Little P, Stuart B, Hobbs FD, et al. DESCARTE investigators. Predictors of suppurative complications for acute sore throat in primary care: prospective clinical cohort study. . Atula T. Corticosteroids for sore throat. Evidence-Based Medicine Guidelines . 2014. . Ebell MH, Smith MA, Barry HC, Ives K, Carey M. The rational clinical examination. Does this patient have strep throat? . Chiappini E, Regoli M

2017 BMJ Rapid Recommendations

105. Guidance on the clinical management of anxiety disorders, specifically focusing on diagnosis and treatment strategies

time, alternative causes of anxiety such as mood or substance use disorders, physical illness or its treatment should be considered (Lampe, 2015; McEvoy et al., 2011). Anxiety disorders are associated with high levels of dis- tress, disability and service use (Slade et al., 2009b), yet only a minority of people with anxiety disorders get ade- quate treatment (Harris et al., 2015). Fewer than half seek treatment by visiting a health professional. Those who do, commonly attend primary care and only (...) management of anxiety disorders also involves consideration of issues for people in various age groups, sociocultural diversity, issues for indigenous cultures, and important comorbidities. First published in the Australian and New Zealand Journal of Psychiatry 2018, Vol. 52(12) 1109-1172.1118 ANZJP Articles Structured clinical interviews. There are four well-established diagnostic interviews that generate a reliable and valid diagnosis: • • Structured Clinical Interview for Axis 1 DSM-IV Disorders

2018 Royal Australian and New Zealand College of Psychiatrists

106. Recurrent uncomplicated urinary tract infections in women: AUA/CUA/SUFU

seeking prevention of urinary tract infections (UTIs) in the operative or procedural setting. In this document, the term UTI will refer to acute bacterial cystitis unless otherwise specified. This document seeks to establish guidance for the evaluation and management of patients with rUTIs to prevent inappropriate use of antibiotics, decrease the risk of antibiotic resistance, reduce adverse effects of antibiotic use, provide guidance on antibiotic and non-antibiotic strategies for prevention (...) Typically, for a diagnosis of cystitis, acute-onset symptoms should occur in conjunction with the laboratory detection of a uropathogen from the urine, typically E. coli (75-95%), but occasionally other pathogens such as other Enterobacteriaceae, P. mirabilis, K. pneumoniae, and S. saprophyticus . Other species are rarely isolated in uncomplicated UTI. 20,21 Urine culture remains the mainstay of diagnosis of an episode of acute cystitis; urinalysis provides little increase in diagnostic accuracy. 22

2019 Canadian Urological Association

107. Bariatric surgery: an HTA report on the efficacy, safety and cost-effectiveness

underwent RYGB at one centre in the US between 2001 and 2007. 86 Of these, 58 (78%) were included in the long-term analysis. At baseline, the mean BMI was 58.5 (±10.5) kg/m². In the first 12 months after gastric bypass, BMI decreased by mean 22.8 (±5.5) kg/m². At mean follow- up of 8.0 years (range 5.4-12.5), the mean BMI was 41.7 (±12.0) kg/m². At the long-term follow-up visit 21 (37%) participants had a BMI 35 kg/m²) individuals. 87 The primary focus in the present paragraph is on the impact (...) Commons Licence http://kce.fgov.be/content/about-copyrights-for-kce-publications. How to refer to this document? Louwagie P, Neyt M, Dossche D, Camberlin C, ten Geuzendam B, Van den Heede K, Van Brabandt H. Bariatric surgery: an HTA report on the efficacy, safety and cost-effectiveness. Health Technology Assessment (HTA) Brussels: Belgian Health Care Knowledge Centre (KCE). 2019. KCE Reports 316. D/2019/10.273/44. This document is available on the website of the Belgian Health Care Knowledge Centre

2019 Belgian Health Care Knowledge Centre

108. Age-friendly and inclusive volunteering: Review of community contributions in later life

Future proofing community contributions 49 Framework for age-friendly, inclusive volunteering 67 Towards lifelong contribution for all 89 Conclusion 90 References Contents5 © Centre for Ageing Better 2018 People in later life make essential contributions to their communities – from volunteering in schools, hospitals and charities, to popping round to visit a neighbour who is ill or alone. They bring a diverse range of skills, talents and life experience to help their communities thrive. We know (...) contributions’? Neighbourliness Informal / Semi-formal Formal Civic As an individual With others more or less spontaneously As part of an established scheme or organisation With others in a more regular or organised way In a formal role as part of a public body e.g. giving a lift, going round for a cup of tea, helping with shopping e.g. taking donations to people in need, helping with local food response, clean-ups after riots e.g. peer support for long-term conditions, organising village fete or street

2018 The Centre for Ageing Better

109. Hydroxychloroquine and Chloroquine Retinopathy Screening

) scans of the macula. Patients should be referred for annual screening after five years of therapy and be reviewed annually thereafter whilst on therapy. At each screening visit patients should undergo 10-2 Humphrey visual field testing, followed by pupillary dilation and imaging with both SD-OCT and widefield fundus autofluorescence imaging (FAF). If widefield FAF is not available, FAF can be acquired in several photographic fields to encompass the macula and extra-macular areas. Patients (...) . Introduction Hydroxychloroquine is used increasingly in the treatment of autoimmune disease with established roles in rheumatology and dermatology (through inhibition and modulation of immune responses) and emerging roles in oncology (through inhibition of autophagy). 1 Chloroquine has a similar mechanism of action although is used far less frequently as it is more toxic to the retina. 2 The increasing use of hydroxychloroquine is for two main reasons: 1. Systemic safety: Hydroxychloroquine has

2018 Royal College of Ophthalmologists

110. Policy on Medically-Necessary Care

. Lee LJ, Bouwens TJ, Savage MF, Vann WF Jr. Examining the cost-effectiveness of early dental visits. Pediatr Dent 2006;28(2):102-5, discussion 192-8. 44. Ladewig NM, Camargo LB, Tedesco TK, et al. Management of dental caries among children: A look at cost-effectiveness. Expert Rev Pharmacoecon Outcomes Res 2018;18(2):127-34. Available at: “https://www.researchgate.net/publication/ 321651003/download”. Accessed August 10, 2019. 45. Foster T, Perinpanayagam H, Pfaffenbach A, Certo M. Recurrence (...) of early childhood caries after comprehensive treatment with general anesthesia and follow-up. J Dent Child 2006;73(1):25-30. 46. Eidelman E, Faibis S, Peretz B. A comparison of restorations for children with early childhood caries treated under general anesthesia or conscious sedation. Pediatr Dent 2000;22(1):33-7. 47. Almeida AG, Roseman MM, Sheff M, Huntington N, Hughes CV. Future caries susceptibility in children with early childhood caries following treatment under general anesthesia. Pediatr Dent

2019 American Academy of Pediatric Dentistry

111. Management of Cardiovascular Diseases during Pregnancy Full Text available with Trip Pro

mobile search navigation Article navigation 07 September 2018 Article Contents Article Navigation 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy Vera Regitz-Zagrosek Chairperson Corresponding authors. Vera Regitz-Zagrosek, Charité Universitaetsmedizin Berlin, Institute for Gender in Medicine, CCR, DZHK, partner site Berlin, Hessische Str 3-4, 10115 Berlin, Germany, Tel: +49 30 450 525 288, Fax: +49 30 450 7 525 288, E-mail: . Search for other works by this author (...) on: Jolien W Roos-Hesselink Co-Chairperson Jolien W. Roos-Hesselink, Department of Cardiology, Erasmus Medical Center Rotterdam, Dr Molewaterplein 40, 3015CGD, Rotterdam, Netherlands, Tel: +31 10 7032432, E-mail: Search for other works by this author on: Johann Bauersachs Search for other works by this author on: Carina Blomström-Lundqvist Search for other works by this author on: Renata Cífková Search for other works by this author on: Michele De Bonis Search for other works by this author on: Bernard

2018 European Society of Cardiology

112. Placenta Praevia and Placenta Accreta: Diagnosis and Management Full Text available with Trip Pro

of Corresponding Author E-mail address: Correspondence : Royal College of Obstetricians and Gynaecologists, 27 Sussex Place, Regent’s Park, London NW1 4RG. Email: on behalf of Corresponding Author E-mail address: Correspondence : Royal College of Obstetricians and Gynaecologists, 27 Sussex Place, Regent’s Park, London NW1 4RG. Email: First published: 27 September 2018 Cited by: This is the fourth edition of this guideline. The first, published in 2001, was entitled Placenta Praevia: Diagnosis and Management (...) edge is less than 20 mm from the internal os on TAS or TVS. [ New 2018 ] Grade of recommendation: D If the placenta is thought to be low lying (less than 20 mm from the internal os) or praevia (covering the os) at the routine fetal anomaly scan, a follow‐up ultrasound examination including a TVS is recommended at 32 weeks of gestation to diagnose persistent low‐lying placenta and/or placenta praevia. Grade of recommendation: D Placenta praevia is a well‐established complication of pregnancy

2018 Royal College of Obstetricians and Gynaecologists

113. Children

, Associated Health Risks, and Treatment Approaches A Scientific Statement From the American Heart (...) Originally published October 7, 2013 Aaron S. Kelly Sarah E. Barlow Goutham Rao Thomas H. Inge Laura L. Hayman Julia Steinberger Elaine M. Urbina Linda J. Ewing Stephen R. Daniels Jump to Abstract Severe obesity afflicts between 4% and 6% of all youth in the United States, and the prevalence is increasing. Despite the serious immediate and long-term cardiovascular, metabolic, and other health (...) and Adolescents Joseph T. Flynn , David C. Kaelber , Carissa M. Baker-Smith , Douglas Blowey , Aaron E. Carroll , Stephen R. Daniels , Sarah D. de 2017 11. International multicentre randomised controlled trial of improvisational music therapy for children with autism spectrum disorder: TIME-A study International multicentre randomised controlled trial of improvisational music therapy for children with autism spectrum disorder: TIME-A study Journals Library An error occurred retrieving content to display

2018 Trip Latest and Greatest

114. Lisinopril

evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory 2018 3. Lisinopril or Coreg CR in reducing cardiotoxicity in women with breast cancer receiving trastuzumab: A rationale and design of a randomized clinical trial. BACKGROUND: Trastuzumab (TZB) is an established therapy for HER2-positive breast cancer. The use of TZB is commonly associated with cardiotoxicity manifesting as asymptomatic decrease in left ventricular (...) in order to explain what the investigators previously observed suggesting that lisinopril , a drug normally used to treat patients with high blood pressure and heart 2011 8. Effect of Chlorthalidone, Amlodipine, and Lisinopril on Visit-to-Visit Variability of Blood Pressure: Results From the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. 24739073 2014 05 15 2015 01 06 2016 12 03 1751-7176 16 5 2014 May Journal of clinical hypertension (Greenwich, Conn.) J Clin Hypertens

2018 Trip Latest and Greatest

115. Zolpidem

and safety of zolpidem extended-release 12.5 mg, administered 3 to 7 nights per week for 24 weeks, in patients with chronic primary insomnia: a 6 (...) -month, randomized, double-blind, placebo-controlled, parallel-group, multicenter study. 79-90 To evaluate long-term efficacy and safety of zolpidem extended-release 3 to 7 nights/week for chronic primary insomnia. Multicenter, 25-week, phase IIIb, randomized, double-blind, placebo-controlled, parallel-group. Outpatient; visits every 4 weeks. Aged 18 (...) sizes for zopiclone and zolpidem on measures of verbal memory. An additional medium effect size 2014 2. Benzodiazepines and zolpidem for chronic insomnia: a meta-analysis of treatment efficacy Benzodiazepines and zolpidem for chronic insomnia: a meta-analysis of treatment efficacy Benzodiazepines and zolpidem for chronic insomnia: a meta-analysis of treatment efficacy Nowell P D, Mazumdar S, Buysse D J, Dew M A, Reynolds C F, Kupfer D J Authors' objectives To assess the efficacy of benzodiazepines

2018 Trip Latest and Greatest

116. ESC/ESH Management of Arterial Hypertension Full Text available with Trip Pro

–creatinine ratio (30–300 mg/g; 3.4–34 mg/mmol) (preferentially on morning spot urine) Moderate CKD with eGFR >30–59 mL/min/1.73 m 2 (BSA) or severe CKD eGFR <30 mL/min/1.73 m 2 b Ankle−brachial index <0.9 Advanced retinopathy: haemorrhages or exudates, papilloedema Established CV or renal disease Cerebrovascular disease: ischaemic stroke, cerebral haemorrhage, TIA CAD: myocardial infarction, angina, myocardial revascularization Presence of atheromatous plaque on imaging Heart failure, including HFpEF (...) (30–300 mg/g; 3.4–34 mg/mmol) (preferentially on morning spot urine) Moderate CKD with eGFR >30–59 mL/min/1.73 m 2 (BSA) or severe CKD eGFR <30 mL/min/1.73 m 2 b Ankle−brachial index <0.9 Advanced retinopathy: haemorrhages or exudates, papilloedema Established CV or renal disease Cerebrovascular disease: ischaemic stroke, cerebral haemorrhage, TIA CAD: myocardial infarction, angina, myocardial revascularization Presence of atheromatous plaque on imaging Heart failure, including HFpEF Peripheral

2018 European Society of Cardiology

117. Neratinib (Nerlynx) - Breast cancer, breast neoplasms

. Neratinib was tolerated in rats for up to 6 months with a NOAEL of 10 mg/kg/day. In dogs, neratinib was tolerated for up to 9 months, and although findings related to faecal disturbance were found the NOAEL for dogs is suggested as 6 mg/kg/day. During examination of covalent binding to human serum albumin, neratinib was shown to bind through a, ß unsaturated amide binding to the e amino group of Lysine190 via a protein-enhanced Michael addition. This binding was species dependent and occurred in human (...) , no effects were detected in oestrous cycling or on mating and embryo survival. The NOAEL was determined to be 12 mg/kg/day. Based on exposure established in the rat 26 week general toxicity study, where a NOAEL of 10 mg/kg/day gave a safety margin of 29-fold based on exposure, the fertility NOAEL provides for a sufficient margin for expected human doses (>29-fold). A statement has been proposed to section 4.6 of the SmPC to reflect that no significant changes in fertility parameters in male and female

2018 European Medicines Agency - EPARs

118. Women and women with children residential rehabilitation best practice

• Longitudinal research to determine the long-term effect of the different models of care • Models of care that have been established in the US need to be evaluated in the Australian setting. Programs such as the Oxford House design (with women living in a share house to support each other) warrants further investigation • Treatment outcomes for diverse cultural groups need to the evaluated. Specific attention should be given to Indigenous communities, where respect is a cultural requirement to ensure client (...) 4 observed the ratio of men and women in rehabilitation is less than the gender prevalence of substance use in the community. Also, women with substance abuse disorders tend to experience more severe medical and social consequences when compared to men. She noted that the odds of completing treatment were three times higher among adult clients in non-hospital residential rehabilitation facilities when compared to those in outpatient methadone programs. These findings suggest that more needs

2018 Sax Institute Evidence Check

119. Inpatient care for children and adolescents with mental disorders

: Randomised Controlled Trials (RCT) (N=5) Boege (2015) 16 GER RCT (8M FU) 1 unit, home care vs inpatient, cost 100 C&A 5-17 M Gowers (2007) 17 UK RCT (2Y FU) 35 units, inpatient vs specialist outpatient vs general CAMHS, anorexia 167 ADOL 12-18 H Harrington (2000) 18 UK RCT (1Y FU) 2 districts, parents of children with behavioural disorders; parent education groups 141 PAR 3-10 M Herpertz-Dahlmann (2014) 19 GER RCT (1Y FU) 6 units, day patient/inpatient vs continued inpatient, anorexia 172 ADOL 11-18 H (...) of the family in the young person’s care. This could involve improving family support (such as making family visits to inpatient care easy), improving family functioning (such as improved parent/child relationships) and providing family therapy as part of the treatment model of care. Another strong predictor of improved treatment outcomes was the provision of accessible post-discharge support and aftercare services. Discharge planning should be undertaken early in the inpatient treatment episode to ensure

2018 Sax Institute Evidence Check

120. Creating a Rapid-learning Health System in Ontario

, based on the best available research evidence and systematically elicited citizen values and stakeholder insights. We aim to strengthen health systems – locally, nationally, and internationally – and get the right programs, services and drugs to the people who need them. Authors John N. Lavis, MD PhD, Director, McMaster Health Forum; Professor, McMaster University; and Adjunct Visiting Professor, University of Johannesburg François-Pierre Gauvin, PhD, Senior Scientific Lead, Citizen Engagement (...) that arise in a rapid-learning health system and it grouped the 67 distinct ethical issues within four phases of the rapid-learning health system: (10) o designing activities: the risk of negative outcomes (e.g., reducing the quality and usability of results) from designing learning activities less rigorously so they are not classified as research, and the risk of inadequate engagement of stakeholders (which can affect the success of the learning activity due to a lack of established trust and support

2018 McMaster Health Forum

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