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81. A cost-utility analysis of biosimilar infliximab compared to reference infliximab in adult switch patients with Crohn’s disease: A Canadian analysis

Policy, Management and Evaluation, University of Toronto, Toronto, Canada John Marshall, MD, MSc Professor and Director of the Division of Gastroenterology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada Myla E. Moretti, MSc, PhD Senior Research Associate, Ontario Child Health Support Unit and the Clinical Trials Unit, The Hospital for Sick Children, Toronto, Ontario, Canada Assistant Professor, Institute for Health Policy, Management and Evaluation, University of Toronto (...) 17 - Administration Costs 77 Table 18 – Immunosuppressive & Steroid Treatment Cost 78 Table 19 - ICD-10 Codes for Crohn's Disease Costs (OCCI 2015/16) 78 Table 20 - Average Surgical Cost Resection & Length of Stay 79 10 Table 21 - Average Surgical Length of Stay 79 Table 22 - Surgical Procedure Fee 79 Table 23 - Surgical Consultations 80 Table 24 - Post Surgical General Surgery Fees 80 Table 25- Ontario Schedule of Benefits: Surgical and Physician Visit Costs 80 Table 26 - Physician Visits 81

2019 SickKids Reports

82. Asymptomatic Bacteriuria

: 2019 Update by the Infectious Diseases Society of America a Lindsay E. Nicolle, 1 Kalpana Gupta, 2 Suzanne F. Bradley, 3 Richard Colgan, 4 Gregory P . DeMuri, 5 Dimitri Drekonja, 6 Linda O. Eckert, 7 Suzanne E. Geerlings, 8 Béla Köves, 9 Thomas M. Hooton, 10 Manisha Juthani-Mehta, 11 Shandra L. Knight, 12 Sanjay Saint, 13 Anthony J. Schaeffer, 14 Barbara Trautner, 15 Bjorn Wullt, 16 and Reed Siemieniuk 17 1 Department of Internal Medicine, School of Medicine, Rady Faculty of Health Sciences (...) transplant recipients followed for 1 year after transplant, with urine routinely screened with culture every 3 days for the first 2 weeks, weekly to 1 month, and at each outpatient follow-up visit, reported that 53% of subjects had at least 1 positive urine culture; 53% of the bacteriuric epi- sodes were considered asymptomatic, and 40% of patients had at least 1 episode of ASB [112]. More than one-half of positive cultures were identified in the first month after transplantation, when screening was most

2019 Infectious Diseases Society of America

83. Urological Infections

, 2002. 287: 2701. 105. Bradbury, S.M. Collection of urine specimens in general practice: to clean or not to clean? J R Coll Gen Pract, 1988. 38: 363. 106. Lifshitz, E., et al. Outpatient urine culture: does collection technique matter? Arch Intern Med, 2000. 160: 2537. 107. Fihn, S.D. Clinical practice. Acute uncomplicated urinary tract infection in women. N Engl J Med, 2003. 349: 259. 108. Foxman, B., et al. Epidemiology of urinary tract infections: transmission and risk factors, incidence (...) , Center for Drug Evaluation and Research (CDER). Complicated Urinary Tract Infections: Developing Drugs for Treatment Guidance for Industry 2018. 11. Johansen, T.E., et al. Critical review of current definitions of urinary tract infections and proposal of an EAU/ESIU classification system. Int J Antimicrob Agents, 2011. 38 Suppl: 64. 12. Singer, M., et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA, 2016. 315: 801. 13. Bell, B.G., et al. A systematic

2019 European Association of Urology

84. BSG consensus guidelines on the management of inflammatory bowel disease in adults

://orcid.org/0000-0002-7442-6093 Matthew J. Brookes: https://orcid.org/0000-0002-8782-0292 Richard Hansen: https://orcid.org/0000-0002-3944-6646 A. Barney Hawthorne: https://orcid.org/0000-0002-8768-4550 Contributors (IBD guidelines eDelphi consensus group) Ian Arnott, Kevin J. Barrett, R. Mark Beattie, Stuart Bloom, Keith Bodger, Richard R. Brady, Matthew J. Brookes, Steven R. Brown, Jeffrey R. Butterworth, Christopher R. Calvert, Rachel Campbell, Tom Creed, Nicholas M. Croft, Fraser Cummings, R. Justin (...) Davies, David Devadason, Anjan Dhar, Chris Dipper, Julie Duncan, Malcolm Dunlop, Dharmaraj Durai, Martyn D. Evans, Omar Faiz, Nicola S. Fearnhead, Alexander C. Ford, Aileen Fraser, Vikki Garrick, Daniel R. Gaya, James Goodhand, Nigel Hall, Richard Hansen, Marcus Harbord, A. Barney Hawthorne, Bu'Hussain Hayee, Sarah Hearnshaw, Paul Henderson, Philip Hendy, Tariq Iqbal, Paul D. Johnston, Nicholas A. Kennedy, Christopher A. Lamb, Jimmy K. Limdi, James O. Lindsay, Alan J. Lobo, Miranda Lomer, Richard E

2019 British Society of Gastroenterology

85. Health technology assessment of a PrEP programme for populations at substantial risk of sexual acquisition of HIV

authority established to promote safety and quality in the provision of health and social care services for the benefit of the health and welfare of the public. HIQA’s mandate to date extends across a wide range of public, private and voluntary sector services. Reporting to the Minister for Health and engaging with the Minister for Children and Youth Affairs, HIQA has responsibility for the following: ? Setting standards for health and social care services — Developing person-centred standards (...) to identify potentially eligible studies. Full text articles were obtained for all citations identified as potentially relevant for inclusion. Both reviewers independently inspected these to establish the relevance of the articles according to the pre-specified criteria. Studies were reviewed for relevance based on study design, types of participants, interventions and outcome measures (see Table 4.1). 4.2.4 Data extraction and management Data were independently extracted using an agreed data extraction

2019 Health Information and Quality Authority

86. Paediatric Urology

tract infections, and the consequences. Pediatrics, 2000. 105: 860. 26. Hiraoka, M., et al. Meatus tightly covered by the prepuce is associated with urinary infection. Pediatr Int, 2002. 44: 658. 27. To, T., et al. Cohort study on circumcision of newborn boys and subsequent risk of urinary-tract infection. Lancet, 1998. 352: 1813. 28. Herndon, C.D., et al. A multicenter outcomes analysis of patients with neonatal reflux presenting with prenatal hydronephrosis. J Urol, 1999. 162: 1203. 29. Ladenhauf (...) : 44. 45. Kaefer, M., et al. The incidence of intersexuality in children with cryptorchidism and hypospadias: stratification based on gonadal palpability and meatal position. J Urol, 1999. 162: 1003. 46. Kollin, C., et al. Cryptorchidism: a clinical perspective. Pediatr Endocrinol Rev, 2014. 11 Suppl 2: 240. 47. Caesar, R.E., et al. The incidence of the cremasteric reflex in normal boys. J Urol, 1994. 152: 779. 48. Barthold, J.S., et al. The epidemiology of congenital cryptorchidism, testicular

2019 European Association of Urology

87. Male Sexual Dysfunction

) for erectile dysfunction: a systematic review and meta-analysis of harms. Urology, 2009. 74: 831. 166. Goldstein, I., et al. Oral sildenafil in the treatment of erectile dysfunction. 1998. J Urol, 2002. 167: 1197. 167. Goldstein, I., et al. Efficacy and Safety of Sildenafil by Age in Men With Erectile Dysfunction. J Sex Med, 2016. 13: 852. 168. Curran, M., et al. Tadalafil. Drugs, 2003. 63: 2203. 169. Ventimiglia, E., et al. The safety of phosphodiesterase type 5 inhibitors for erectile dysfunction. Expert (...) . Urol Clin North Am, 2001. 28: 355. 263. Bettocchi, C., et al. Patient and partner satisfaction after AMS inflatable penile prosthesis implant. J Sex Med, 2010. 7: 304. 264. Chung, E., et al. Penile prosthesis implantation for the treatment for male erectile dysfunction: clinical outcomes and lessons learnt after 955 procedures. World J Urol, 2013. 31: 591. 265. Falcone, M., et al. Prospective analysis of the surgical outcomes and patients’ satisfaction rate after the AMS Spectra penile prosthesis

2019 European Association of Urology

88. Management of Non-neurogenic Male LUTS

with monotherapy and placebo in patients with overactive bladder (SYNERGY study). BJU Int, 2017. 120: 562. 235. Chapple, C.R., et al. Persistence and Adherence with Mirabegron versus Antimuscarinic Agents in Patients with Overactive Bladder: A Retrospective Observational Study in UK Clinical Practice. Eur Urol, 2017. 72: 389. 236. Van Gelderen, M., et al. Absence of clinically relevant cardiovascular interaction upon add-on of mirabegron or tamsulosin to an established tamsulosin or mirabegron treatment (...) Management of Non-neurogenic Male LUTS Management of Non-neurogenic Male LUTS | Uroweb › Management of Non-neurogenic Male LUTS Management of Non-neurogenic Male LUTS To access the pdfs & translations of individual guidelines, please as EAU member. Non-EAU members can view the web versions. To become an EAU member, click . S. Gravas (Chair), J.N. Cornu, M. Gacci, C. Gratzke, T.R.W. Herrmann, C. Mamoulakis, M. Rieken, M.J. Speakman, K.A.O. Tikkinen Guidelines Associates: M. Karavitakis, I

2019 European Association of Urology

89. Chronic Pelvic Pain

. 93: 568. 131. Bartoletti, R., et al. Prevalence, incidence estimation, risk factors and characterization of chronic prostatitis/chronic pelvic pain syndrome in urological hospital outpatients in Italy: results of a multicenter case-control observational study. J Urol, 2007. 178: 2411. 132. Gonen, M., et al. Prevalence of premature ejaculation in Turkish men with chronic pelvic pain syndrome. J Androl, 2005. 26: 601. 133. Mehik, A., et al. Fears, sexual disturbances and personality features in men (...) : 253. 315. Tamaki, M., et al. Possible mechanisms inducing glomerulations in interstitial cystitis: relationship between endoscopic findings and expression of angiogenic growth factors. J Urol, 2004. 172: 945. 316. Aihara, K., et al. Hydrodistension under local anesthesia for patients with suspected painful bladder syndrome/interstitial cystitis: safety, diagnostic potential and therapeutic efficacy. Int J Urol, 2009. 16: 947. 317. Messing, E., et al. Associations among cystoscopic findings

2019 European Association of Urology

90. European Academy of Neurology guideline on trigeminal neuralgia

neuralgia Corresponding Author E-mail address: Department of Neurology, Faculty of Health and Medical Sciences, Danish Headache Center, Rigshospitalet‐Glostrup, University of Copenhagen, Glostrup, Denmark Correspondence: L. Bendtsen, Danish Headache Center, Department of Neurology, Rigshospitalet‐Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, 2600 Glostrup, Denmark (tel.: +45 38633065; fax: +45 38633839; e‐mail: ). Pain Management Centre, National Hospital for Neurology (...) Schildautal, Seesen, Germany Department of Neurology and Danish Pain Research Center, Aarhus University Hospital, University of Aarhus, Aarhus C, Denmark Department of Human Neuroscience, Sapienza University, Rome, Italy Corresponding Author E-mail address: Department of Neurology, Faculty of Health and Medical Sciences, Danish Headache Center, Rigshospitalet‐Glostrup, University of Copenhagen, Glostrup, Denmark Correspondence: L. Bendtsen, Danish Headache Center, Department of Neurology, Rigshospitalet

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2019 European Academy of Neurology

91. Principles of Pediatric Patient Safety: Reducing Harm Due to Medical Care

. Cottrell EK , O’Brien K , Curry M , et al . Understanding safety in prehospital emergency medical services for children. O’Neill KA , Shinn D , Starr KT , Kelley J . Patient misidentification in a pediatric emergency department: patient safety and legal perspectives. Heilman JA , Flanigan M , Nelson A , Johnson T , Yarris LM . Adapting the I-PASS handoff program for emergency department inter-shift handoffs. Shahian DM , McEachern K , Rossi L , Chisari RG , Mort E . Large-scale implementation of the I (...) errors occurred per 1000 patients. Pediatric errors in the ambulatory setting have more limited published studies despite the fact that children have far more outpatient than hospital care interactions. , , The Learning From Errors in Ambulatory Pediatrics study revealed 147 medical errors reported in 14 practices over 4 months (no denominator was reported). The largest group of errors was attributed to medical treatment (37%). Other errors included patient identification (22%); preventive care

2019 American Academy of Pediatrics

92. Prostate Cancer

Prostate Cancer Prostate Cancer | Uroweb › Prostate Cancer Prostate Cancer To access the pdfs & translations of individual guidelines, please as EAU member. Non-EAU members can view the web versions. To become an EAU member, click . N. Mottet (Chair), R.C.N. van den Bergh, E. Briers (Patient Representative), P. Cornford (Vice-chair), M. De Santis, S. Fanti, S. Gillessen, J. Grummet, A.M. Henry, T.B. Lam, M.D. Mason, T.H. van der Kwast, H.G. van der Poel, O. Rouvière, D. Tilki, T. Wiegel (...) Guidelines Associates: T. Van den Broeck, M. Cumberbatch, N. Fossati, T. Gross, M. Lardas, M. Liew, L. Moris, I.G. Schoots, P-P.M. Willemse TABLE OF CONTENTS REFERENCES 1. Drost, F.J.H., et al. Prostate MRI, with or without MRI-targeted biopsy, and systematic biopsy for detecting prostate cancer. Cochrane Database of Systematic Reviews, 2019. In press. 2. Van den Broeck, T., et al. Prognostic Value of Biochemical Recurrence Following Treatment with Curative Intent for Prostate Cancer: A Systematic Review

2019 European Association of Urology

93. Male Infertility

to recommendations. BMJ, 2008. 336: 1049. 7. Bruins M., et al. What is the effectiveness and harm of medical and/or nutritional therapy on the pregnancy rate in couples with idiopathic male infertility? PROSPERO: International prospective register of systematic reviews, 2016. ;ID=CRD42016032976 8. WHO, WHO Manual for the Standardized Investigation and Diagnosis of the Infertile Couple. 2000, Cambridge University Press: Cambridge. 9. Greenhall, E., et al. The prevalence of subfertility: a review of the current (...) , 2013. 15: 795. 25. Ben-Yosef, D., et al. Testicular sperm retrieval and cryopreservation prior to initiating ovarian stimulation as the first line approach in patients with non-obstructive azoospermia. Hum Reprod, 1999. 14: 1794. 26. Borges, E., Jr., et al. Testicular sperm results in elevated miscarriage rates compared to epididymal sperm in azoospermic patients. Sao Paulo Med J, 2002. 120: 122. 27. Ghanem, M., et al. Comparison of the outcome of intracytoplasmic sperm injection in obstructive

2019 European Association of Urology

94. Enhancing Health Promotion and Disease Prevention in Networked Primary Care

, M.Sc., Lead, Evidence Synthesis, McMaster Health Forum Ahmed A. Belal, M.Sc., Research Assistant, Evidence Synthesis, McMaster Health Forum Eilish M. Scallan, M.Sc., Research Assistant, Evidence Synthesis, McMaster Health Forum Michael G. Wilson, PhD, Assistant Director, McMaster Health Forum, and Associate Professor, McMaster University Timeline Rapid syntheses can be requested in a three-, 10-, 30-, 60- or 90-business-day timeframe. This synthesis was prepared over a 30-businessday timeframe (...) primary care or have outlined plans to implement networked primary care in the health system. In Saskatchewan, the Ministry of Health in the most recent annual report has outlined actions to establish primary-care networks in Regina and Saskatoon.(4) Similarly, the Nova Scotia Health Authority’s guiding document for primary-care delivery outlines a Health Home model, which will use a population-health approach to primary care, and include wellness and chronic-disease management across a geographic

2018 McMaster Health Forum

95. Improving social and emotional wellbeing for Aboriginal and Torres Strait Islander people

, discrimination, violence, victimisation, offending and social disadvantage. 6, 7 There also needs to be a focus on reducing these stressors (risks) and improving the capacity of community members and service staff to cope with these. Thus, the concept provides a holistic perspective on what are commonly understood as mental health concerns, and acknowledges the impact of the social and cultural determinants of health. Indigenous SEWB is ?rmly established as a national strategic priority. 8 Beyond Blue (...) to risk (i.e. understanding risk and mental health promotion, and developing tailored early intervention and prevention strategies); and 4) establishing improved engagement, screening, management and referral pathways. The latter is critically important: 80% of adolescents (10–24 years) from 114 primary healthcare services were not screened for social and emotional wellbeing concerns. Of those screened, no further action was taken for 14% of all clients for whom concerns were identified

2018 Sax Institute Evidence Check

96. Bioresorbable Stents in cardiovascular indications (coronary artery disease)

hospitalisation or outpatient visits [7]. Therefore, revascularisation should ideally prolong life expectancy, reduce symptoms and future revascularisations, and increase health-related quality of life. Safety: Adverse events (AEs) • vascular access site complication • procedure-related contrast-induced nephropathy Bioresorbable stents for cardiovascular indications Version 1.4, 28 January 2019 EUnetHTA Joint Action 3 WP4 19 SAEs • late/very late (after =1 year) ScT and/or stent thrombosis and its (...) (studies) Quality Comments Risk with DES or other revascularisation strategies Risk with DESolve ® Scaffold System Effectiveness All-cause mortality — — — — — Outcome not reported Cardiac mortality — — — — — Outcome not reported MI — — — — — Outcome not reported Safety Periprocedural mortality — — — 345 ??? ? very low 5 No events of periprocedural mortality occurred in three single-arm observational studies of the DESolve ® Scaffold System Periprocedural MI — — — 345 ??? ? very low e One periprocedural

2019 EUnetHTA

97. The Collaborative Assessment, OTCA12, on “C-reactive protein point-of-care testing (CRP POCT) to guide antibiotic prescribing in primary care settings for acute respiratory tract infections (RTIs)

consumption correlates with in- creased antibiotic resistance, with countries that have moderate to high consumption of antibiotics also having high levels of AMR. However, a causal link between antibiotic consumption and re- sistance is difficult to establish. (A0002) At the patient level, there is a clear link between antibiotic dose and duration and the emergence of antibiotic resistance. There is also evidence that patients who have been treated frequently with antibiotics are at greater risk (...) not generally recommend the use of antibiotics in acute sinusitis, it is unclear what the aim of CRP testing, on its own or as part of a clinical prediction rule, would be even if a suitable threshold could be established. In pharyngitis/tonsillitis, treatment with antibiotics is generally only recommended in those with group A streptococcal (GAS) infection (5% to 30% of those presenting with sore throat). A cut-point of 35 mg/L CRP may be useful in discriminating bacterial from non-bacterial pharyngitis

2019 EUnetHTA

98. Society of Interventional Radiology Multisociety Consensus Position Statement on Prostatic Artery Embolization for Treatment of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia

, x 41 Maclean, D., Harris, M., Drake, T. et al. Factors predicting a good symptomatic outcome after prostate artery embolisation (PAE). Cardiovasc Intervent Radiol . 2018 ; 41 : 1152–1159 , x 42 Rampoldi, A., Barbosa, F., Secco, S. et al. Prostatic artery embolization as an alternative to indwelling bladder catheterization to manage benign prostatic hyperplasia in poor surgical candidates. Cardiovasc Intervent Radiol . 2017 ; 40 : 530–536 , x 43 Salem, R., Hairston, J., Hohlastos, E. et al (...) techniques. Cardiovasc Intervent Radiol . 2017 ; 40 : 366–374 , x 40 Kurbatov, D., Russo, G.I., Lepetukhin, A. et al. Prostatic artery embolization for prostate volume greater than 80 cm3: results from a single-center prospective study. Urology . 2014 ; 84 : 400–404 , x 41 Maclean, D., Harris, M., Drake, T. et al. Factors predicting a good symptomatic outcome after prostate artery embolisation (PAE). Cardiovasc Intervent Radiol . 2018 ; 41 : 1152–1159 , x 43 Salem, R., Hairston, J., Hohlastos, E. et al

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2019 Society of Interventional Radiology

99. WHO Guidelines for the pharmacological and radiotherapeutic management of cancer pain in adults and adolescents

the University of Wisconsin-Madison Pain and Policies Studies Group was an observer at the first scoping meeting. He was then appointed to the GDG as a member. 2 Eric Krakauer first joined the guideline development process as a member of the WHO Steering Com - mittee, and following his departure from WHO joined the GDG as a member.7 ACKNOWLEDGEMENTS Systematic Review team members: Ethan M Balk (Lead), Gaelen P Adam, Mengyang Di, Hannah J Kimmel, Matthew Olean, Jessica K Roydhouse, Bryant Smith, Andrew R (...) This recommendation applies to people who already have painful bone metastases; it does not apply to people whose bone metastases are not painful. The GDG acknowledged that other established practices exist for treatment of cancer pain, but evidence of efficacy is limited. Regarding such practices, the clinician may consider an individual trial of therapy and cease the medicine if no improvement in pain occurs. Ideally, eligible patients should be enrolled in a clinical trial wherever pos- sible to expand

2019 World Health Organisation Guidelines

100. Day-case surgery

if their child becomes unwell before the day of surgery. This can prevent late cancellations, avoiding the wasteoftheatreresourcesandunnecessarytripstohospital with a child who is not ?t for the procedure and may be an infectionrisk. Pre-anaesthetic assessment is also an opportunity to establish who has parental responsibility and to ensure that appropriate consent procedures are followed. Written consent for the procedure may already have been obtained in the outpatient setting, but a discussion regarding (...) members of a working party established by the Association of Anaesthetists of Great Britain and Ireland and the British Association of Day Surgery (BADS). It has been seen and approvedbytheAssociationofAnaesthetist’sBoardofDirectorsandtheCouncilofBADS.Ithasbeenendorsedbythe Association of Paediatric Anaesthetists of Great Britain and Ireland (APAGBI) and the Royal College of Anaesthetists (RCoA). Twitter:@drcrbailey Re-use of this article is permitted in accordance with the Creative Commons Deed

2019 Association of Anaesthetists of GB and Ireland

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