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21. Vitamin E Toxicity (Treatment)

Vitamin E Toxicity (Treatment) Vitamin Toxicity Treatment & Management: Approach Considerations, Inpatient Care Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. processing > Vitamin Toxicity (...) Syst Rev . 2012 Mar 14. 3:CD007176. . Office of Dietary Supplements. Dietary Supplement Fact Sheet: Vitamin E. National Institutes of Health. Available at . Accessed: October 13, 2014. Institute of Medicine. Food and Nutrition Board. Dietary Reference Intakes (DRIs): Recommended Dietary Allowances and Adequate Intakes, Vitamins. Available at . Accessed: October 13, 2014. Tan KP, Kosuge K, Yang M, Ito S. NRF2 as a determinant of cellular resistance in retinoic acid cytotoxicity. Free Radic Biol Med


22. Venous thromboembolic diseases: diagnosis, management and thrombophilia testing

rationale and impact. Full details of the evidence and the committee's discussion are in evidence review E: outpatient treatment of low-risk pulmonary embolism. 1.3 1.3 Anticoagulation treatment for suspected or Anticoagulation treatment for suspected or confirmed DVT or PE confirmed DVT or PE NICE has also produced a visual summary of the recommendations on anticoagulation treatment for DVT or PE. 1.3.1 When offering anticoagulation treatment follow the recommendations on shared decision making (...) -of-rights). Page 2 of 47Contents Contents Overview 5 Who is it for? 5 Recommendations 6 1.1 Diagnosis and initial management 6 1.2 Outpatient treatment for low-risk PE 12 1.3 Anticoagulation treatment for suspected or confirmed DVT or PE 13 1.4 Long-term anticoagulation for secondary prevention 18 1.5 Information and support for people having anticoagulation treatment 20 1.6 Thrombolytic therapy 21 1.7 Mechanical interventions 22 1.8 Investigations for cancer 23 1.9 Thrombophilia testing 24 T erms used

2020 National Institute for Health and Clinical Excellence - Clinical Guidelines

23. Therapeutic guidelines for antiretroviral (ARV) treatment of adult HIV infection

individuals. AIDS 2014; 28:257-65. 2. Cheung C, Ding E, Sereda P, Yip B, Lourenco L, Barrios R, Montaner JSG, Hogg RS, Lima V, Moore D. Reductions in all-cause and cause-specific mortality among HIV-infected individuals receiving antiretroviral therapy in British Columbia, Canada: 2001-2012. HIV Medicine 2016 Oct; 17(9):694-701. 3. Hoenigl M, Chaillon A, Moore DJ, Morris SR, Mehta SR, Gianella S, Amico KR, Little SJ. Rapid HIV viral load suppression in those initiating antiretroviral therapy at first (...) visit after HIV diagnosis. Scientific reports. 2016 Sep 6; 6:32947. 4. Ford N, Migone C, Calmy A, Kerschberger B, Kanters S, Nsanzimana S, Mills EJ, Meintjes G, Vitoria M, Doherty M, Shubber Z. Benefits and risks of rapid initiation of antiretroviral therapy. AIDS (London, England). 2018 Jan 2; 32(1):17. 5. World Health Organization. Guidelines for managing advanced HIV disease and rapid initiation of antiretroviral therapy, July 2017. 6. Pilcher CD, Ospina-Norvell C, Dasgupta A, Jones D

2020 CPG Infobase

24. Canadian guidelines on opioid use disorder among older adults

Psychia- try Rep. 2016;18(9):87. Epub 2016/08/05. 45. Loreck D, Brandt NJ, DiPaula B. Managing opioid abuse in older adults: clinical considerations and challenges. J Gerontol Nurs. 2016;42(4):10–15. Epub 2016/03/31. 46. Maree RD, Marcum ZA, Saghafi E, et al. A systematic review of opioid and benzodiazepine misuse in older adults. Am J Geriatr Psychiatry. 2016;24(11):949–63. Epub 2016/10/19. 47. Burgos-Chapman I, Trevisan L, Sevarino K. Abuse of opioids and prescription medications. In: Sullivan M (...) -Agonist-Therapy 67. Nosyk B, Sun H, Evans E, et al. Defining dosing pattern charac - teristics of successful tapers following methadone maintenance treatment: results from a population-based retrospective cohort study. Addiction. 2012;107(9):1621–29. Epub 2012/03/06. 68. W alley A Y , Doe-Simkins M, Quinn E, et al. Opioid overdose pre- vention with intranasal naloxone among people who take metha- done. J Subst Abuse Treat. 2013;44(2):241–47. Epub 2012/09/18. 69. Walley AY , Xuan Z, Hackman HH, et al

2020 CPG Infobase

25. Genome-Wide Sequencing for Unexplained Developmental Disabilities or Multiple Congenital Anomalies

11 Early identification of genetic diagnoses could also help clinical decisions target potential intervention, monitoring, and optimal patient management and could establish realistic expectations for the child’s development. 10 Health Technology Under Review The genetic makeup of our bodies (deoxyribonucleic acid, or DNA) contains the information used as building blocks for all cells in the body. An error in the genetic code can lead to a person having impaired development or function (...) condition. For example, a condition could be due to alteration of proteins observable only with biochemical examinations to identify an anomaly with no known genetic link in an ultra-rare disease. 16 When an established target gene or multi-gene panel that covers all known genes associated with a suspected disorder is available, it is still recommended over genome-wide sequencing due to these challenges (email from various committee experts, November 2018 through June 2019). Physical harm associated

2020 Health Quality Ontario

26. Continual Long-Term Physiotherapy After Stroke

therapy. 5 March 2020 Ontario Health Technology Assessment Series; Vol. 20: No. 7, pp. 1–70, March 2020 8 Health Service Under Review Physiotherapy After Stroke Physiotherapy (also sometimes known as physical rehabilitation) is delivered by physiotherapists (also sometimes known as physical therapists) in many different practice settings, including acute care and rehabilitation hospitals, outpatient clinics, long-term care homes, and primary care facilities. The goal of therapy after stroke (...) to address upper and lower extremity weakness, as well as hemiplegic shoulder pain. 6 Ontario Context In Ontario, physiotherapy is commonly delivered in acute care, inpatient, and outpatient settings, as well as in home and community care settings. After a stroke, physiotherapy typically begins in acute care with a focus on comprehensive assessment, and early mobilization to optimize safe and independent capacity for bed mobility, transfers, and walking. Patients transferred to inpatient rehabilitation

2020 Health Quality Ontario

27. Gene Expression Profiling Tests for Early-Stage Invasive Breast Cancer

status), molecular subtype, or specific gene expression. The most common staging system for breast cancer is the TNM system from the American Joint Committee on Cancer (AJCC), which factors the size of the tumour and its extension (T), the lymph node involvement (N), and the metastasis (M). 2 The TNM system recognizes five stages of breast cancer 2 : • Stage 0 (noninvasive): abnormal cells are present but have not spread to nearby tissue; also known as carcinoma in situ • Stage 1 (invasive): cancer (...) is compared with each of the four molecular subtypes to determine the degree of similarity. The results are combined with a proliferation score and tumour size to establish the Risk of Recurrence (ROR) score. 23 The ROR score is correlated with the 10-year probability of distant recurrence, with risk groups categorized as low ( 20%) ROR. 24 Regulatory Information Gene expression profiling tests are considered laboratory-developed tests and therefore do not require Health Canada approval unless

2020 Health Quality Ontario

28. Implantable Devices for Single-Sided Deafness and Conductive or Mixed Hearing Loss

e,m High f,l Low High Abbreviation: ROBIS, Risk of Bias in Systematic Reviews. a Possible risk of bias levels: low, high, unclear. b Single reviewer for data extraction and study quality assessment, with data from 10% of the studies being extracted by two reviewers. c Single reviewer for study selection with another assessing those studies over which there was doubt. d Single reviewer for data extraction and checked by a second reviewer. e Unclear on the number of reviewers for study selection (...) Risk of Bias in the Review University of Alberta, 2011 47 Low Low High b Low Low Appachi et al, 2017 44 Low Low Low Low Low Australia Medical Services Advisory Committee, 2010 34 Low High c High d Low High Bezdjian et al, 2017 48 Low Low Low Low Low Colquitt et al, 2011 49 Low Low Low Low Low Danhauer et al, 2010 50 Low High e High f Low High Ernst et al, 2016 51 Low High g Low Low Low Kim et al, 2017 45 Low Low High h Low Low Kiringoda and Lustig, 2013 56 Low High e High f Low High Kitterick et al

2020 Health Quality Ontario

29. Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy Full Text available with Trip Pro

for the majority, but not for everyone. Strong All or nearly all informed people would likely want this option. Benefits outweigh harms for almost everyone. Visit the MAGICapp multiple comparison tool to compare and choose options Evidence summaries Screening options should be chosen in shared decision making, based on a person’s individual risk of cancer For a person with a 2% risk of colorectal cancer within 15 years Colorectal cancer mortality No screening FIT every year Sigmoidoscopy FIT every two years (...) and preferences FIT Sigmoidoscopy Done at home every year or every two years for 15 years Done once in 15 years at an outpatient clinic/hospital Stool from one bowel movement is collected with a stick and mailed for analysis Preparation with bowel enema on the day of the procedure. Sometimes combined with oral laxatives Preparation with oral laxatives starting the day before procedure Individuals with a positive test are offered colonoscopy Usually performed with no sedation, so no recovery time necessary

2019 BMJ Rapid Recommendations

30. Recommendations for good practice in Ultrasound: Oocyte retrieval Full Text available with Trip Pro

search navigation Article Navigation 2019 Article Contents Article Navigation Recommendations for good practice in ultrasound: oocyte pick up The ESHRE Working Group on Ultrasound in ART Search for other works by this author on: , Arianna D’Angelo Wales Fertility Institute , University Hospital of Wales, Cardiff University, Cardiff, UK Correspondence address. Wales Fertility Institute, University Hospital of Wales, Heath Park, Cardiff CF14 4XW, UK. E-mail: , Search for other works by this author (...) and volume of follicles. Caution should be taken in correlating these new parameters with oocyte maturity in comparison with conventional mean follicular diameter. The transvaginal transducer, or probe, should have a frequency range of 5–8 MHz and an abdominal transducer with a frequency range of 2–6 MHz, or their contemporaneous equivalents at the time of purchase. An appropriate protocol for transducer disinfection should be established, in accordance with manufacturer’s instructions. OPU operators

2020 European Society of Human Reproduction and Embryology

31. Effectiveness of mental health electronic medical records

) Automation through e-prescribing has, on the other hand, resulted in improved care quality and safety, especially in clinical contexts where effective socio-technical systems have been established. (11) However, the mismatch between what “off-the-shelf” EMRs offer and what clinicians need is well recognised. (12) The impacts of EMRs have seldom been systematically studied, measured and reported in the peer-reviewed literature related to mental health service delivery. To maximise the benefits of EMRs (...) EMRs – Columbia Suicide Severity Rating Scale 300 evaluations performed by 36 psychiatry residents Quantitative: chart review Not specified Xiao & Acosta (2016) USA Adult outpatient psychiatric clinic e-charting custom developed for use in the clinic, included intake notes, evaluation/assessment, progress notes and e- medication monitoring 105 charts review pre- implementation and 141 charts reviewed post- implementation Quantitative: chart review Not specified Literature reviews relevant to EMRs

2020 Sax Institute Evidence Check

32. Suicide aftercare services

Suggested Citation: Shand F, Woodward A, McGill K, Larsen M, Torok M et al. Suicide aftercare services: an Evidence Check rapid review brokered by the Sax Institute ( for the NSW Ministry of Health, 2019. Disclaimer: This Evidence Check Review was produced using the Evidence Check methodology in response to specific questions from the commissioning agency. It is not necessarily a comprehensive review of all literature relating to the topic area. It was current at the time (...) , rather than relying on the person to make contact with the service. It may also require using a range of methods to maintain contact, such as home and other off-site visits, telephone calls and texts. Note SUICIDE AFTERCARE SERVICES | SAX INSTITUTE 7 that not all of aftercare services would be defined as ‘assertive’. Brief interventions typically provide a limited number of sessions (usually fewer than six) and/or the sessions were of limited duration (10-20 minutes). The duration of the effect

2020 Sax Institute Evidence Check

33. Raising the bar on strength and balance: The importance of community-based provision

trained to support instructors during class as well as accompanying instructors on home visits to encourage community-based class attendance. This has been particularly effective in trying to engage older men in SBEP. Wigan: Reaching out to men Work across stakeholder groups Falls need to be everybody’s business, which is why establishing a falls collaborative group that includes representatives from all stakeholder and key influencers, works as an important factor in developing a co-ordinated (...) , accessible homes and connected communities. By focusing on those approaching later life and at risk of missing out, we will create lasting change in society. We are bold and innovative in our approach to improving later lives. We work in partnership with a diverse range of organisations. As a part of the What Works network, we are grounded in evidence. To find out more visit: The Healthy Ageing Research Group at the University of Manchester The Healthy Ageing Research Group

2020 The Centre for Ageing Better

34. Guidance for maternal medicine in the evolving coronavirus (COVID-19) pandemic

for adaptation of maternal medicine services to safely reduce face-to-face contact during the evolving coronavirus pandemic, for example by offering virtual consultations where appropriate, ensuring women are seen in one-stop clinics that cover all medical and obstetric needs in the same visit, avoiding unnecessary hospital admissions and offering new innovations, such as home monitoring of blood pressure, where it is safe to do so. • Specific advice for healthcare professionals caring for pregnant women (...) . A minority of maternal medicine clinic appointments will need to be face-to-face, primarily when the woman is having a physical interaction such as an obstetric scan, an echocardiogram, or an exchange transfusion. Face-to- face interactions should be limited by reviewing the purpose of the appointment in advance (ideally one week earlier) and ensuring that the relevant tests/treatments can all be done in a single visit. For many non-pregnant patients this is already happening as medical specialties adapt

2020 Royal College of Obstetricians and Gynaecologists

35. Covid-19: Infrared Temperature Screening to Identify Potentially Infected Staff or Visitors Presenting to Healthcare Facilities during Infectious Disease Outbreaks

Covid-19: Infrared Temperature Screening to Identify Potentially Infected Staff or Visitors Presenting to Healthcare Facilities during Infectious Disease Outbreaks CLINICAL EVIDENCE ASSESSMENT Share Your Feedback on how this report answered your question by visiting © March 2020 ECRI Infrared Temperature Screening to Identify Potentially Infected Staff or Visitors Presenting to Healthcare Facilities during Infectious Disease Outbreaks Temperature monitoring during infectious (...) and healthcare provider (includes outpatient, nursing homes/long-term care facilities, inpatient, telehealth) - Implement changes to visitor policies to further limit exposures to HCP, residents, and patients. Changes could include temperature/ symptom checks for visitors, limiting visitor movement in the facility, etc. - Interim U.S. Guidance for Risk Assessment and Public Health Management of Healthcare Personnel with Potential Exposure in a Healthcare Setting to Patients with Coronavirus Disease (COVID-19

2020 Covid-19 Ad hoc papers

36. Rational use of personal protective equipment for coronavirus disease (COVID-19)

possible, to establish differentiated care pathways that minimize mixing of known or suspected COVID-19 patients with other patients (e.g. through separate health facilities, wards, waiting, and triage areas). • Environmental and engineering controls aim at reducing the spread of pathogens and the contamination of surfaces and inanimate objects. They include providing adequate space to allow social distance of at least 1 m to be maintained between patients and health care workers and ensuring (...) -19 virus, such as glass or plastic windows. This approach can be implemented in areas of the health care setting where patients will first present, such as triage and screening areas, the registration desk at the emergency department, or at the pharmacy window where medication is collected. • Postpone elective, non-urgent procedure, and hospitalizations, reduce frequency of visits for chronic patients, apply telemedicine and telephone solutions where possible so that health care workers, wards

2020 WHO Coronavirus disease (COVID-19) Pandemic

37. The Geriatricians’ Perspective on Medical Services to Residential Aged Care Facilities (RCFs) in Australia.

, Ikegami N, Ljunggren G, Carrilo E, Fries B. Rug-III and resource allocation: comparing the relationship of direct care time with patient characteristics in five countries. Age and Ageing 1997 26- S2:61-65. 9. Hawes C, Morris J, Phillips C, Fries B, Murphy K, Mor V. Development of the nursing home Resident Assessment Instrument in the USA. Age and Ageing 1997 26-S2: 19-25 10. Fries B, Scholl M, Hawes C, Gilgen, Jonsson P, Park P. Approaching cross- national comparisons of nursing home residents. Age (...) and Guidelines for the Enhanced Primary-Care Medicare Benefits Schedule Items. Royal Australian College of General Practitioners. 2001. Commonwealth of Australia 46. van Haastregt JCM, Diederiks JPM, van Possum E, et al. Effects of preventative home visits to elderly people living in the community: systematic review. British Medical Journal. 2000: 320: 754-758. 47. Stuck AE, Siu AL, Wieland GD, et al. Comprehensive geriatric assessment: a meta-analysis of controlled trials. Lancet 1993, 342: 1032-1036. 48

2020 Australian and New Zealand Society for Geriatric Medicine

38. ESC Guidance for the Diagnosis and Management of CV Disease during the COVID-19 Pandemic Full Text available with Trip Pro

coronavirus disease 2019 ( ) has reached pandemic levels; Patients with cardiovascular ( ) risk factors and established cardiovascular disease ( ) represent a vulnerable population when suffering from ; Patients with cardiac injury in the context of have an increased risk of morbidity and mortality. The causing has reached pandemic levels since March 2020. In the absence of vaccines or curative medical treatment, exerts an unprecedented global impact on public health and health care delivery. Owing (...) previously. not only causes viral pneumonia but has major implications for the system. Patients with risk factors including male sex, advanced age, diabetes, hypertension and obesity as well as patients with established and cerebrovascular disease have been identified as particularly vulnerable populations with increased morbidity and mortality when suffering from . Moreover, a considerable proportion of patients may develop cardiac injury in the context of which portends an increased risk of in-hospital

2020 European Society of Cardiology

39. Assisted Vaginal Birth

Assisted Vaginal Birth Assisted Vaginal Birth - Murphy - - BJOG: An International Journal of Obstetrics & Gynaecology - Wiley Online Library COVID-19 campus closures: see options for to subscribed content. By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term Search term RCOG Green‐top Guidelines Free Access Assisted Vaginal Birth Green‐top Guideline No. 26 on behalf of Corresponding Author E-mail address (...) : Correspondence: Royal College of Obstetricians and Gynaecologists, 10–18 Union Street, London SE1 1SZ. Email: on behalf of Corresponding Author E-mail address: Correspondence: Royal College of Obstetricians and Gynaecologists, 10–18 Union Street, London SE1 1SZ. Email: First published: 28 April 2020 This is the fourth edition of this guideline, first published in October 2000 under the title Instrumental vaginal delivery , and revised in January 2011 and October 2005 under the title Operative Vaginal

2020 Royal College of Obstetricians and Gynaecologists

40. Safe Reintroduction of Cardiovascular Services during the COVID-19 Pandemic: Guidance from North American Societies Full Text available with Trip Pro

Journal of Cardiology. 2020; ( March 24th ) , Shah PB, Welt FGP, Mahmud E, et al. Triage Considerations for Patients Referred for Structural Heart Disease Intervention During the Coronavirus Disease 2019 (COVID-19) Pandemic: An ACC /SCAI Consensus Statement. JACC Cardiovasc Interv. 2020. , Kirkpatrick J.N. Mitchell C. Taub C. Kort S. Hung J. Swaminathan M. ASE Statement on Protection of Patients and Echocardiography Service Providers During the 2019 Novel Coronavirus Outbreak. J Am Coll Cardiol. 2020 (...) . References Zhu N. Zhang D. Wang W. et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med. 2020; 382 : 727-733 Holshue M.L. DeBolt C. Lindquist S. et al. First Case of 2019 Novel Coronavirus in the United States. N Engl J Med. 2020; 382 : 929-936 Bhatraju PK, Ghassemieh BJ, Nichols M, et al. Covid-19 in Critically Ill Patients in the Seattle Region - Case Series. N Engl J Med. 2020. Driggin E. Madhavan M.V. Bikdeli B. et al. Cardiovascular Considerations for Patients, Health

2020 Covid-19 Ad hoc guidelines

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