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2981. Management of patients with asthma in the emergency department and in hospital

with the use of succinylcholine. Discharge treatment plan and follow-up care Spirometry and clinical assessment are used to establish risk of relapse. Important risk factors include admission to hospital or a visit to the emergency department in the previous 12 months, recent use of glucocorticosteroids, use of multiple categories of asthma medication, a previous severe or life-threatening asthma attack and the presence of psychosocial problems.[ – ] The most compelling evidence for using oral (...) 1995 ; 155 : 496 -500. 116. Browne GJ, Penna AS, Phung X, Soo M. Randomised trial of intravenous salbutamol in early management of acute severe asthma in children. Lancet 1997 ; 349 : 301 -5. 117. Kelly HW, Murphy S. Should we stop using theophylline for the treatment of the hospitalized patient with status asthmaticus? DICP 1989 ; 23 : 995 -8. 118. Huang D, O'Brien RG, Harman E, Aull L, Reents S, Visser J, et al. Does aminophylline benefit adults admitted to the hospital for an acute exacerbation

1999 CPG Infobase

2982. Guidelines for the Management of Colorectal Cancer

MR Thompson Mr WJ Cunliffe Dr I Geh Dr M Hill Dr A Hartley Mr A Radcliffe Dr E Levine Dr A Higginson Prof GT Williams Prof P Quirke Prof M G Dunlop Association of Coloproctology of Great Britain and Ireland Prof MG Dunlop Mr I MacLennan Prof D Morton Prof JMA Northover Prof NS Williams Royal College of Physicians Prof R Logan Prof J Rhodes Royal College of General Practitioners Dr P Sutton Royal College of Radiologists Dr S Taylor Professor T Maughan (Oncology) Royal College of Surgeons (...) -disciplinary team 26 iii) Surgical specialisation 27 Process 28 i) Preparation for surgery 28 a) Informed consent 29 b) Preparation for stoma formation 30 c) Cross-matching 30 d) Bowel preparation 30 e) Thrombo-embolism prophylaxis 31 f) Antibiotic prophylaxis 31 g) Enhanced recovery 32 ii) Rates of curative resection 32 iii) Definition of Rectal Tumour 32 iv) Surgical technique 33 a) Resection 33 b) Anastomosis 34 v) Rates of permanent stoma formation 35 vi) Local excision 35 vii) Laparoscopic surgery 36

2007 Association of Coloproctology of Great Britain and Ireland

2983. Management of Thyroid Cancer

of Sheffield Pat Kendall-Taylor (Chair) MD, DCH, FRCP, Professor of Endocrinology, Newcastle-upon-Tyne Geoffrey J Beckett BSc, PhD, FRCPath, Reader in Clinical Biochemistry, Edinburgh Penny M Clark PhD, FRCPath, Consultant Clinical Scientist, Birmingham Susan EM Clarke MSc, FRCP, Consultant Physician/Senior Lecturer, Guys and St Thomas’ Hospital, London Richard Collins FRCS(Eng), FRCS(Ed), Consultant Surgeon, Canterbury Sharon Dobbins Chief Librarian, Sunderland Royal Hospital Trust John Farndon BSc, MD

2007 British Association of Endocrine and Thyroid Surgeons

2984. Resources for Coloproctology

Association of Coloproctology website, www.acpgbi.org.uk). In some instances data was updated from the analysis undertaken for the 2001 reports whereas in others the data remained valid. 1 Association of Coloproctology (ACP) Audit 2000 of surgeons’ programmes including outpatients operations 2 Radiology – a national survey of the services required 3 Endoanal ultrasound (EAUS) and anorectal physiology (ARP) – survey of established units (revised 2005) 4 Endoscopy – British Society of Gastroenterology (BSG (...) visit to Outpatients. Flexible sigmoidoscopy has been shown to be effective for the diagnosis of significant serious diseases such as cancer, colitis and diverticular disease, but rigid sigmoidoscopy with or without a barium enema is still the most common mode of investigation in Outpatients in the UK. The recent introduction of the Government’s ‘Two Week Standard’ has increased pressure on Outpatients, but has also focused attention on current serious deficiencies in the system and service. d de em

2006 Association of Coloproctology of Great Britain and Ireland

2985. Management of febrile children in the age of the conjugate pneumococcal vaccine: a cost-effectiveness analysis

analysis. Pediatrics 2001; 108(4): 835-844 PubMedID Other publications of related interest Baraff L, Lee S, Schriger D L. Outcomes of bacterial meningitis in children: a meta-analysis. Pediatric Infectious Disease Journal 1993;12:389-394. Carroll W, Farrell M, Singer J, Jackson M, Lobel J, Lewis E. Treatment of occult bacteremia: a prospective randomised clinical trial. Pediatrics 1983;72:608-612. Lieu T, Schwartz S, Jaffe D, Fleisher G. Strategies for diagnosis and treatment of children at risk (...) Management of febrile children in the age of the conjugate pneumococcal vaccine: a cost-effectiveness analysis Management of febrile children in the age of the conjugate pneumococcal vaccine: a cost-effectiveness analysis Management of febrile children in the age of the conjugate pneumococcal vaccine: a cost-effectiveness analysis Lee G M, Fleisher G R, Harper M B Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract

2001 NHS Economic Evaluation Database.

2986. Cost-effectiveness analysis of interferon as adjuvant therapy in high-risk melanoma patients in Spain

Cost-effectiveness analysis of interferon as adjuvant therapy in high-risk melanoma patients in Spain Cost-effectiveness analysis of interferon as adjuvant therapy in high-risk melanoma patients in Spain Cost-effectiveness analysis of interferon as adjuvant therapy in high-risk melanoma patients in Spain Gonzalez-Larriba J L, Serrano S, Alvarez-Mon M, Camacho F, Casado M A, Diaz-Perez J L, Diaz-Rubio E, Fosbrook L, Guillem V, Lopez-Lopez J J, Moreno-Nogueira J A, Toribio J Record Status (...) therapy in countries where other adjuvant therapies with similar costs are used to treat other types of cancer. Source of funding None stated. Bibliographic details Gonzalez-Larriba J L, Serrano S, Alvarez-Mon M, Camacho F, Casado M A, Diaz-Perez J L, Diaz-Rubio E, Fosbrook L, Guillem V, Lopez-Lopez J J, Moreno-Nogueira J A, Toribio J. Cost-effectiveness analysis of interferon as adjuvant therapy in high-risk melanoma patients in Spain. European Journal of Cancer 2000; 36(18): 2344-2352 PubMedID Other

2000 NHS Economic Evaluation Database.

2987. The economic impact of a multifactorial intervention to improve postoperative rehabilitation of hip fracture patients

care and non-medical (community-based) care. The direct medical costs comprised the cost of office-based and outpatient clinic physician care, emergency room care, acute hospital care, post-hospital discharge rehabilitation care in a long-term facility, nursing home care, radiological and laboratory tests that were not part of the hospital stay, physical and/or occupational therapy, visiting nurse care and prescription drugs. The direct non-medical costs included homemaker assistance (...) The economic impact of a multifactorial intervention to improve postoperative rehabilitation of hip fracture patients The economic impact of a multifactorial intervention to improve postoperative rehabilitation of hip fracture patients The economic impact of a multifactorial intervention to improve postoperative rehabilitation of hip fracture patients Ruchlin H S, Elkin E B, Allegrante J P Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion

2001 NHS Economic Evaluation Database.

2988. Cost-effectiveness of systematic depression treatment for high utilizers of general medical care

of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study population comprised patients aged between 23 and 63 years of age, who were members in participating clinics and high-users of medical services, that is to say those whose number of outpatient medical visits exceeded the 85th percentile for each of the last two years (either 7 or 8 visits per year). Patients were excluded if they had received active depression treatment during the last 90 days (...) adopted reflected the perspective of the study. The cost items included in the analysis were screening and treatment co-ordinator (only for DMP group) and outpatient and inpatient intervention programme costs, such as specialty outpatient visits, antidepressant prescriptions, and other prescriptions or services. The estimation of resources used was derived from actual data obtained from health plan administrative data systems and estimation of costs was based on actual data, derived from Medicare's

2001 NHS Economic Evaluation Database.

2989. Adjunctive lamotrigine therapy in patients with refractory seizures: a lifetime cost-utility analysis

hospital treatment (excluding treatment of drug reaction, surgical workup and operation), outpatient physicians visits, EEG services, CT scan and MRI, serum-level test (excluding drug reactions), drug-reaction costs, drug treatment costs, surgical workup, operation, and 500mg lamotrigine cost. The cost calculation was conducted from a societal perspective. The cost data (except for the lamotrigine cost) were extracted from an article published in 1994. The lamotrigine cost was obtained from the Red (...) to be treated with some caution. The issue of generalisability to other settings or countries was not addressed. Source of funding None stated. Bibliographic details Messori A, Trippoli S, Becagli P, Cincotta M, Labbate M G, Zaccara G. Adjunctive lamotrigine therapy in patients with refractory seizures: a lifetime cost-utility analysis. European Journal of Clinical Pharmacology 1998; 53(6): 421-427 PubMedID Other publications of related interest Matsuo F, Bergen D, Faught E et al. Placebo-controlled study

1998 NHS Economic Evaluation Database.

2990. Implementation of local guidelines for cost-effective management of hypertension: a trial of the firm system

Implementation of local guidelines for cost-effective management of hypertension: a trial of the firm system Implementation of local guidelines for cost-effective management of hypertension: a trial of the firm system Implementation of local guidelines for cost-effective management of hypertension: a trial of the firm system Aucott J N, Pelecanos E, Dombrowski R, Fuehrer S M, Laich J, Aron D C Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) of prescriptions). The items measured were operational costs (including drugs used and follow up costs and costs of complications such as clinic visits, emergency room visits, hospitalisations and outpatient laboratory services). The cost boundary adopted was the hospital. The estimation of quantities was based on actual data. The prices used were those prevailing in 1992. The source of quantities and cost data was the Decentralized Hospital Computer Program (DHCP). The quantity of resources was measured from

1996 NHS Economic Evaluation Database.

2991. Clinical practice guidelines for the management of advanced breast cancer

it as a reference to be used in cooperation with their doctor and other health care professionals with whom they are involved.5 Clinical practice guidelines for the management of advanced breast cancer S U M M A RY O F G U I D E L I N E S The following table provides a summary of the guidelines presented in this document. Each of the recommendations should be considered in the care and management of women with advanced breast cancer. To understand the context of this evidence, readers should turn (...) , and previous type of therapy (for example, hormone or chemotherapy). 2821 Clinical practice guidelines for the management of advanced breast cancer C H A P T E R 2 T H E I M PAC T O F A DVA N C E D B R E A S T C A N C E R 2 .1 QUA LI T Y OF LI FE A ND PS YC H OS OCI A L I SS UE S Quality of life is a multidimensional construct that is generally accepted to include several important areas or domains of a person’s life: physical functioning, psychological functioning, social functioning, sexual functioning

2000 Cancer Australia

2992. Clinical practice guidelines for the management of early breast cancer

on the woman 17 1.6 The effect on the family 18 2. General principles of care 21 2.1 Aims of treatment 21 2.2 Establishing good communication practices 22 2.3 Counselling and support 29 2.4 Choosing a specialist 32 2.5 Second opinion 34 2.6 Disclosure of risk 34 2.7 Clinical trials 35 2.8 Pregnancy 37 2.9 Complementary and alternative therapies 38 3. Before definitive treatment 41 3.1 History 42 3.2 Clinical examination 42 3.3 Investigations 43 3.4 Pathology 47iv Clinical practice guidelines (...) Clinical practice guidelines for the management of early breast cancer Appendices A. Development of the first edition (1995) 111 B. Revision of the first edition (1995) and production of the second edition (2001) 121 C. TNM clinical classification 139 D. RACOG Bulletin Vol 10, No 1, May 1996 (working party on tamoxifen and the endometrium) 141 E. Questions you may be asked 145 F. iSource National Breast Cancer Centre Publications List 149 G. Types of clinical trials 153 H. Breast cancer support

2001 Cancer Australia

2993. Clinical practice guidelines for the psychosocial care of adults with cancer

B. Persons involved in the development of the Psychosocial clinical practice guidelines: providing information and support for women with breast cancer 127 C. Guideline development process 128 D. Incidence of cancers in Australia in 1998 137 E. Resources and contacts for patients and the treatment team 138 F . Financial assistance for travel and accommodation 149 G. Recommendations for strategies to overcome barriers to effective psychosocial referral 149 H. Services for people from culturally (...) Recommended steps for preparing patients for transition to palliative care 67 3.3A Recommended steps involved in ensuring that all people with cancer have adequate emotional and social support 70 3.3B Support sources that can improve the emotional well-being of people with cancer 73 3.5 Recommended steps for establishing continuity of care 79 3.6 Recommended steps involved in providing end of life support 84 3.7A Effective strategies/techniques that can be utilised by treatment team members to improve

2002 Cancer Australia

2994. [Assessment of an electronic referral and teleconsultation system between secondary and primary health care]

E, Paavola T, Carlson C, Viikinkoski P, Bockerman M, Kaariainen P, Ohinmaa A Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Harno K, Arajarvi E, Paavola T, Carlson C, Viikinkoski P, Bockerman M, Kaariainen P, Ohinmaa A. Etapoliklinikan arviointi - Peijaksen etapoliklinikkaprojektin loppuraportti. [Assessment of an electronic referral (...) and teleconsultation system between secondary and primary health care] Helsinki: Finnish Office for Health Care Technology Assessment (FinOHTA). FinOHTA Report No. 10. 1999 Authors' objectives The aim of this study was firstly to examine the ability of telemedicine supported outpatient clinics in Peijas Hospital to improve and replace present health care chains and, secondly, to compare the computer supported outpatient clinical model with outpatient clinics in Hyvinkaa hospital lacking these facilities and also

1999 Health Technology Assessment (HTA) Database.

2996. Predicting the future: Can this patient with acute congestive heart failure be safely discharged from the emergency department?

failure be safely discharged from the emergency department? x Margaret Hsieh , MD , x Thomas E. Auble , PhD , x Donald M. Yealy , MD Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, PA. DOI: | Figure. List of major inhospital complications in the 1996 study by Chin et al. x 10 Chin, M and Goldman, L. Correlates of major complications or death in patients admitted to the hospital with congestive heart failure. Arch Intern Med . 1996 ; 156 : 1814–1820 | | Hide Pane Expand all (...) complications or death in patients admitted to the hospital with congestive heart failure. Arch Intern Med . 1996 ; 156 : 1814–1820 | | , x 11 Chin, M and Goldman, L. Correlates of early hospital readmission or death in patients with congestive heart failure. Am J Cardiol . 1997 ; 79 : 1640–1644 | | | | | and 1 study of both inpatients and outpatients x 12 Cowie, MR, Wood, DA, Coats, AJS et al. Survival of patients with a new diagnosis of heart failure: a population based study. Heart. 2000 ; 83 : 505–510

2002 Evidence-Based Emergency Medicine

2997. How good is a negative cranial computed tomographic scan result in excluding subarachnoid hemorrhage?

is recommended by most physicians in the situation of a patient with an acute, severe headache, normal neurologic examination, and normal CT findings. x 3 Edlow, J and Caplan, L. Pitfalls in the diagnosis of subarachnoid hemorrhage. N Engl J Med . 2000 ; 342 : 29–36 | | | , x 4 Mayberg, MR, Batjer, HH, Dacey, R et al. Guidelines for the management of aneurysmal subarachnoid hemorrhage. Stroke . 1994 ; 25 : 2315–2328 | | | , x 5 Vermeulen, M. Subarachnoid haemorrhage: diagnosis and treatment. J Neurol . 1996 (...) ; 243 : 496–501 | | | , x 6 Vermeulen, M and van Gijn, J. The diagnosis of subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry . 1990 ; 53 : 365–372 | | | The CSF is examined for blood and xanthochromia. Ideally, you would like to see a study that performs LP in all patients being evaluated for SAH—those with both negative and positive CT scan findings. However, in reality, because of the practice convention alluded to above, you think it unlikely that you will find a study in which LP has been

2000 Evidence-Based Emergency Medicine

2998. Risk Assessment and Prevention of Pressure Ulcers

implementation! Doris Grinspun, RN, MSN, PhD(cand), OOnt Executive Director Registered Nurses’ Association of Ontario1 Nursing Best Practice Guideline Program Team: Tazim Virani, RN, MScN, PhD(candidate) Program Director Heather McConnell, RN, BScN, MA(Ed) Program Manager Stephanie Lappan-Gracon, RN, MN Program Coordinator – Best Practice Champions Network Josephine Santos, RN, MN Program Coordinator Jane M. Schouten, RN, BScN, MBA Program Coordinator Bonnie Russell, BJ Program Assistant Carrie Scott (...) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 Appendix C: Braden Scale for Predicting Pressure Sore Risk . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60 Appendix D: Risk and Related Interventions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 Appendix E: Staging of Pressure Ulcers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 Appendix F: Pressure Reduction and Pressure

2002 Registered Nurses' Association of Ontario

2999. Inhalatives Insulin (Exubera)

during phase 2 and phase 3 clinical studies of inhaled insulin (Exubera) in patients with type 1 or type 2 diabetes: P46. Diabetologia 2002; 45(Suppl 2): A17. 4. Cefalu WT, Sercarevic-Pehar, M. for the Exubera Phase 3 Study Group. Long-term use of Exubera in Type 2 Diabetes: observations on glycemic control, pulmonary function and antibody formation: P356OR. Diabetes 2005; 54(Suppl 1): A88. 5. Teeter JG, the E, Pfizer-Global-Research-and-Development-GCU. One-year pulmonary safety and efficacy (...) of diabetes -Presence of late complications at the start of the study -If a meta-analysis established that there was substantial heterogeneity between the studies, the characteristics responsible for this heterogeneity, in so far as these could be identified. Page 17 of 70 Assignm ent No. A05-22: Inhaled Insulin (Exubera®) - Rapid Report Page 18 of 70 4. Results The results of the information acquisition will be presented first. This is followed by the presentation of the relevant studies

2006 Institute for Quality and Efficiency in Healthcare (IQWiG)

3000. Clopidogrel versus acetylsalicylic acid for the secondary prevention of vascular diseases

of vascular diseases 10 Appendix D.2: Response from M. Hamel for J. Drazen (Chan 2005) 155 Appendix D.3: Response from F. Chan (Chan 2005) 156 Appendix D.4: Response from D. Zarin (WATCH trial) 158 Appendix D.5: Response from B. Massie (WATCH trial) 159 APPENDIX E: MATCH TRIAL 161 APPENDIX F: PROTOCOL OF THE SCIENTIFIC HEARING 162 APPENDIX G: STATEMENTS IN WRITING 162 LIST OF TABLES Table 1: Study pool 37 Table 2: Overview of studies 41 Table 3: Inclusion and exclusion criteria 43 Table 4: Baseline (...) : - In patients with MI (a few days up to 35 days previously), an ischaemic stroke (7 days up to 6 months previously), or with proven PAD; - In combination with ASA: in patients with non-ST-elevation ACS (unstable angina pectoris or non-Q-wave MI). Antiplatelet therapy is an established treatment to prevent vascular events in patients with atherosclerosis. In patients with previous MI, stroke or TIA who were treated for 2 years, antiplatelet therapy reduced the rate of vascular events (non-fatal MI, non-fatal

2006 Institute for Quality and Efficiency in Healthcare (IQWiG)

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