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Dysuria in Children

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161. Clinical Applications of Contrast-Enhanced Ultrasonography in Pediatric Population

years. No adverse events were reported at 1 hour after exam. Follow-up phone interviews revealed no adverse events in the majority (973 of 1,010). The remaining 37 children experienced mild symptoms including dysuria (n=26) and urinary retention (n=2) which may have been related to catheterization rather than the contrast agent. A recent European survey at 29 centers evaluating the use of ultrasound contrast agent in 4,131 children for pediatric reflux diagnosis reported no adverse events (Riccabona (...) Last Update Posted : January 25, 2018 Sponsor: Johns Hopkins University Information provided by (Responsible Party): Johns Hopkins University Study Details Study Description Go to Brief Summary: In children, specifically the intravesicle administration to study vesicoureteral reflux in children already catheterized and scheduled for voiding cystourethrogram (VCUG). Contrast-enhanced ultrasonography is a tremendous advancement from conventional B-mode and color Doppler ultrasonography, as it permits

2016 Clinical Trials

162. Surgical Complications Following Early Genitourinary Reconstructive Surgery for Congenital Adrenal Hyperplasia- Interim Analysis at 6 Years. (PubMed)

patients from April 2003 to April 2015 who underwent genitourinary reconstructive surgeries. Demographic data and surgical postoperative complications (per Unplanned Postoperative Morbidity in Children [UPMC] and Clavien-Dindo classification) were evaluated.The average age at the time primary surgery was done at our institute was 17 ± 20 (5-87) months; the average length of follow-up was 72.56 ± 36.95 (4.5-142) months. The average length of the common urogenital sinus was 4.5 ± 1.9 (2.5-6.4) cm, and 15 (...) out of 22 (68%) patients had high confluence. A total of 7 complications were observed in 7 (27%) patients, 3 patients had Clavien grade I and UPMC 0 (dysuria, stitch dehiscence, wound separation), and 2 had Clavien grade II and UPMC 1 (urinary tract infection). Two (7.6%) patients required revision surgery, and both of them had Clavien grade IIIB. One patient had UPMC score 5 (suprapubic tube insertion for urinary retention secondary to cicatrization of the surgical site).Genitourinary

2016 Urology

163. How to create a modern superhero

How to create a modern superhero How to create a modern superhero How to create a modern superhero | | September 23, 2016 168 Shares You start out by working in a busy emergency department. You see patients with all sorts of complaints: abdominal pain, headaches, and chest pain. Vomiting, diarrhea, and dysuria. Ankle sprains, bug bites, and allergic reactions. Domestic violence, rape, and child abuse. You don’t ever let the stress of the job take away your humanity. You treat your patients (...) editor, and then publish it. You dedicate it to the courageous men, women, and children who have survived sexual, psychological, or physical assault and who are soldering on. Alberto Hazan is an emergency physician and author of and series. Image credit: … … 168 Shares Tagged as: Subscribe to KevinMD and never miss a story! Get free updates delivered free to your inbox. Subscribe Hire KevinMD to keynote your next event "Kevin's keynote presentation was perfect. Extremely rich in content

2016 KevinMD blog

164. What is the outcome of paediatric gastrocystoplasty when the patients reach adulthood? (PubMed)

What is the outcome of paediatric gastrocystoplasty when the patients reach adulthood? To document the long-term outcomes of paediatric augmentation gastrocystoplasty (AGC) in terms of preservation of renal function and maintenance of dryness, and to analyse the rate of complications.The medical records of children who had undergone AGC between 1992 and 2000 (minimum time interval of 15 years) were reviewed retrospectively. The following data were collected: age at surgery, the cause of bladder (...) -19.5) years. Renal function was preserved or improved in seven of the 11 patients and nine patients were dry after AGC. Seven of the 11 patients reported symptoms linked to haematuria-dysuria syndrome, which was resistant to treatment in one case and requiring excision of the gastric patch. Three of the 11 patients developed a tumour on the gastric graft after a median (range) delay of 20 (11-22) years after the initial procedure. All had gastric adenocarcinoma of which two were metastatic

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2016 BJU international

165. GreenLight XPS for treating benign prostatic hyperplasia

Prostate Symptom Score [IPSS] and International Prostate Symptom Score Quality of Life [IPSS- QOL], change in prostate volume, maximum flow rate [Qmax], post-void residual volume [PVR]) duration of catheterisation rate of dysuria (pain) quality of life length of hospital stay frequency of completion as a day-case rate of re-admission procedural blood loss and blood transfusion need rate of transurethral resection of the prostate (TURP) syndrome rate of capsular perforation device-related adverse events (...) and Healthcare Products Regulatory Agency Professor Janelle Y Professor Janelle Y ork orke e Lecturer and Researcher in Nursing, University of Manchester Dr Amber Y Dr Amber Y oung oung Consultant Paediatric Anaesthetist, Bristol Royal Hospital for Children GreenLight XPS for treating benign prostatic hyperplasia (MTG29) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 26 of 30NICE lead team Each medical technology assessment

2016 National Institute for Health and Clinical Excellence - Medical technologies

166. Articles of the month Special Edition: Pediatric UTI

, and the post is primarily based on what I have seen as common practice in North America. The vast majority of children treated for potential urinary tract infections in North America do not have specific urinary symptoms. They are worked up just because they have a fever. That is why the guidelines talk about renal disease and not managing discomfort – the antibiotics can’t be for the dysuria, because there is none. If a child has specific urinary symptoms, I absolutely think they should be treated (...) of work to read dense papers full of opaque statistical tests when there were guidelines that would summarize all that evidence for me. So as a resident, I just religiously followed the guidelines. That meant sending hundreds of children to the ED for cath urines, ordering VCUGs, and prescribing a lot of antibiotics. Unfortunately, once I was exposed to the evidence, this management plan seemed like madness. In fact, I think the practice I learned in residency was probably hurting children. So let’s

2016 First10EM

167. Articles of the month (February 2016)

, and make sure you catch it in specimen bottle. Does it work? Of the 80 patients they tried this on (no comparison group), they were successful in 69 (86%). Median time to sample collection was 45 seconds. My only concern is if I miss the urine and I have to start all over again (maybe after antibiotics). This is interesting, but I so rarely get newborn urines, I will probably stick with a Foley for now. Bottom line: You can make children pee using this technique. Not sure where to fit (...) dysuria, based on their definition of ‘non-inferiority’, although the actual numbers for pain look pretty similar. Also there were 5 patients in the ibuprofen group who developed pyelonephritis as compared to only one in the fosfomycin group, although the difference was not statistically significant (p=0.12). I think antibiotics help, but this study reminds us that if you are on the fence, there is no reason to rush the antibiotics. Nearly 7/10 women will clear their UTI without your help. Also

2016 First10EM

168. Child maltreatment: when to suspect maltreatment in under 16s

30 2.5 Recurrent abdominal pain 30 More information 30 Update information 31 Child maltreatment: when to suspect maltreatment in under 18s (CG89) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 3 of 32Ov Overview erview This guideline covers the signs of possible child maltreatment in children and young people aged under 18 years. It aims to raise awareness and help health professionals who are not child (...) features) that may be observed when a child presents to healthcare professionals. Its purpose is to raise awareness and help healthcare professionals who are not specialists in child protection to identify children who may be being maltreated. It does not give healthcare professionals recommendations on how to diagnose, confirm or disprove child maltreatment. Children may present with both physical and psychological symptoms and signs that constitute alerting features of one or more types

2009 National Institute for Health and Clinical Excellence - Clinical Guidelines

169. Avibactam sodium / ceftazidime (Avycaz)

in children 3 months to less than 18 years with a suspected or confirmed bacterial infection and receiving other systemic antibacterial therapy was recently completed. Pending determination of appropriate doses for each age group, a multiple-dose, active-controlled trial will be recommended to evaluate safety, tolerability and efficacy of CAZ-AVI in children with cUTI and cIAI from 3 months to less than 18 years of age. An additional PK and safety study to include neonates from birth to 3 months

2015 FDA - Drug Approval Package

170. Zerbaxa - ceftolozane / tazobactam

in children and adolescents below 18 years of age have not yet been established. No data are available. Method of administration Zerbaxa is for intravenous infusion. The infusion time is 1 hour for 1 g / 0.5 g of Zerbaxa. Precautions to be taken before handling or administering the product See section 6.2 for incompatibilities. See section 6.6 for instructions on reconstitution and dilution of the medicinal product before administration. 2.2. Quality aspects 2.2.1. Introduction The finished product

2015 European Medicines Agency - EPARs

171. Edistride - dapagliflozin

/EC. 2.4.2. Conclusions on the clinical efficacy The CHMP considers that the clinical data are acceptable to support the marketing authorisation. Assessment report EMA/679678/2015 Page 6/27 2.5. Clinical safety The applicant makes reference to module 5 of the marketing authorisation application of Edistride The most common side effects are hypoglycaemia (when used with a sulphonylurea or insulin), urinary tract infection, genital tract infection, dyslipidaemia, dysuria and polyuria. Specific (...) this medicine. Pediatric population Product labeling: Posology and method of administration: Paediatric population The safety and efficacy of dapagliflozin in children aged 0 to < 18 years have not yet been established. No data are available. Patient information Children and adolescents Forxiga is not recommended for children and adolescents under 18 years of age, because it has not been studied in these patients. Not applicable Pregnancy / Nursing mothers Product labeling: Fertility, pregnancy

2015 European Medicines Agency - EPARs

172. Ebymect - dapagliflozin / metformin

makes reference to module 5 of the marketing authorisation application of Xigduo. The most common side effects are hypoglycaemia, nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, vulvovaginitis, balanitis and related genital infections, urinary tract infection, dysuria and polyuria. Specific safety issues regarding a tumour imbalance in dapagliflozin treated patients, the limited data available in patients > 75 years old, the use in patients at risk of volume depletion, hypotension (...) : Warnings and precautions If you are 75 years old or older, you should not start taking this medicine. This is because you may be more prone to some side effects. If you are taking another medicine for diabetes that contains “pioglitazone”, you should not start taking this medicine. Not applicable Pediatric population Product labeling: Posology and method of administration: Paediatric population The safety and efficacy of Xigduo in children aged 0 to < 18 years have not yet been established. No data

2015 European Medicines Agency - EPARs

174. Pharmacological interventions for preventing complications in idiopathic hypercalciuria. (PubMed)

Pharmacological interventions for preventing complications in idiopathic hypercalciuria. Idiopathic hypercalciuria is an inherited metabolic abnormality characterised by excessive amounts of calcium excreted into the urine in patients with normal serum levels of calcium. The morbidity of hypercalciuria is related to kidney stone disease and bone demineralization. In children, hypercalciuria can cause recurrent haematuria, frequency-dysuria syndrome, urinary tract infection and abdominal

2009 Cochrane

175. CPG on the Diagnosis, Treatment and Prevention of Tuberculosis

Latent Infection in Children 138 6.3.6. Treating Latent Infection in Pregnant Women 140 6.3.7. Treating Contacts of Patients with Multi-Drug Resistant Tuberculosis 141 6.3.8. Duration of Protection 141 6.3.9. The Impact of Treatment on Resistance to Isoniazid 142 6.3.10. Compliance with Treatment for Latent Infection 142 6.3.11. Liver Toxicity of Isoniazid 144 6.3.12. Other Drugs Used to Treat Latent Infection 145 6.4. Treating Probable Infection (Primary Chemoprevention) 147 6.5. Vaccination 150 (...) is the diagnostic performance of interferon-gamma release assays in diag- nosing latent tuberculosis infection? 3. What are the clinical and radiological characteristics of pulmonary tuberculosis in adults? 4. What are the clinical and radiological characteristics of pulmonary tuberculosis in children? 5. What is the diagnostic performance of the various sampling methods available in diagnosing pulmonary tuberculosis in adults and children? 6. What is the diagnostic performance of microscopic sputum examination

2010 GuiaSalud

176. UroLift for treating lower urinary tract symptoms of benign prostatic hyperplasia

noted no cases of urinary incontinence or sexual dysfunction. Minor complications included transient dysuria (70%) and urgency (40%), and slight haematuria (30%). Two patients (10%) needed post-operative catheterisation. The authors stated that longer follow-up times and larger patient numbers were needed before conclusions could be made on the safety and efficacy of the technology. An average of 3.8 UroLift implants was used per patient. 3.11 Chin et al. (2012) and Woo et al. (2012) both reported (...) reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 11 of 35some patients continued to show a 34% symptomatic improvement. Similar improvements were shown in BPHII and quality of life. Results were statistically significant for all of these outcomes at all time intervals. No decrease in sexual function was observed, and the MSHQ-EjD showed significant improvements at some intervals. Adverse events were minor, such as dysuria and haematuria

2015 National Institute for Health and Clinical Excellence - Medical technologies

177. Kidney Stones 01: Presentation

likely to be seen upon presentation in adolescents than school-aged children ( ). Ureteral stones are more painful, as the spasm is intense, and older children and adolescents have them two thirds of the time. Hematuria Gross hematuria is less frequent than the microscopic version in one-third to one-half of patients. Note that some voids may be bloody, others not for the individual patient. noted that the absence of gross hematuria had a 100% NPV – but it was only 24 patients. Dysuria Only one (...) Kidney Stones 01: Presentation Kidney Stones 01: Presentation – PEMBlog Search for: Search for: Kidney Stones 01: Presentation This is part of the four part PEMBlog series on kidney stones. Throughout you’ll learn about diagnosis and management of an increasingly recognized problem in the Pediatric Emergency Department. History Family history is suggestive in about 1/7 children with stones. Metabolic disorders (intestinal malabsorption) are risk factors. In children with metabolic disorders

2015 PEM Blog

178. Composite Paraganglioma and Neuroblastoma of the Urinary Bladder: A Rare Histopathological Entity (PubMed)

Composite Paraganglioma and Neuroblastoma of the Urinary Bladder: A Rare Histopathological Entity Paraganglioma of the urinary bladder is an uncommon clinical entity. Neuroblastoma of the urinary bladder is another rare tumor with only 7 reported cases, all in children. This report presents the case of a composite paraganglioma and neuroblastoma in a 45 year-old male who presented with dysuria and flank pain. On the computerized tomography scan, the bladder wall overlying the tumor was smooth

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2015 Current urology

179. Labial adhesion and bacteriuria (PubMed)

Labial adhesion and bacteriuria The purpose of this study is to evaluate the clinical presentation, laboratory findings, and response to treatment in girls with labial adhesion younger than 23 months.A retrospective chart review of all girls younger than 23 months with the diagnosis of labial adhesion was referred to Dr Sheikh children's clinic in Mashhad in northeast Iran between 1998 and 2013.Sixty-three patients were diagnosed with labial adhesion during the review period. Most patients were (...) diagnosed by physicians during the physical examination or during the evaluation for their voiding problems. The most prevalent symptom among patients was dysuria and restlessness while voiding. Twenty-one (33.3%) patients had a history of urinary tract infection. 17 (26.9%) patients had sterile pyuria and 69.8% showed presence of bacteria in their urine samples.Physicians may frequently encounter pre-pubertal girls whose urinalysis may show sterile pyuria or presence of bacteria with colony counts <105

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2015 Journal of the Turkish German Gynecological Association

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