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Dysuria in Children

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142. Dapagliflozin (Forxiga) in type 2 Diabetes Mellitus. Urinating glucose has its problems

or insulin). Frequent (1/100 to <1/10): Vulvovaginitis, balanitis and genital infections, urinary tract infections, back pain, dysuria, polyuria, dyslipidaemia, increase in he- matocrit. Less frequent (1/1.000 to <1/100): Vulvovaginal pruritus, volume depletion, thirst, constipation, hyperhidrosis, nicturia, increase in blood creatinin levels, increase in blood urea. 1,2 The incidence of adverse effects with dapa- gliflozin in monotherapy was 22% compared to 15% under metformin. Severe adverse effects (...) a year. Renal function should be monitored befo- re initiating treatment with drugs that can affect its function and thereafter regularly. If ClCr<60 mL/min or GFR<60 mL/min/1.73 m 2 then treatment should be stopped. 1,2 Li- ver failure: in cases of severe liver failure, the initial recommended dose is 5 mg daily, and if well tolerated it can be increased up to 10 mg. No dose adjustments are required for mild and moderate live impairment. 1,2 Children: there are no data in children under 18 year

2014 Drug and Therapeutics Bulletin of Navarre (Spain)

143. Management of Trichomonas vaginalis infection

] ? 10-50% are asymptomatic. ? The commonest symptoms include vaginal discharge, vulval itching, dysuria, or offensive odour, but these are not specific for TV. ? Occasionally the presenting complaint is of low abdominal discomfort or vulval ulceration. Males [4-6] ? 15 to 50% of men with TV are asymptomatic and usually present as sexual partners of infected women. ? The commonest presentation in symptomatic men is with urethral discharge and/or dysuria. ? Other symptoms include urethral irritation (...) examination. ? 5-15% of women will have no abnormalities on examination. Males [4-6] ? Urethral discharge (20-60% men) - usually small or moderate amounts only, and or dysuria. ? No signs, even in the presence of symptoms suggesting urethritis: one recent prospective study of infected TV contacts found 77.3% were asymptomatic. ? Rarely balanoposthitis. 3 Complications There is increasing evidence that TV infection can have a detrimental outcome on pregnancy and is associated with preterm delivery and low

2014 British Association for Sexual Health and HIV

145. Suprapubic urinary catheter

record ( ). The child’s doctor must be informed if the child: is unable to pass urine ( ) has dysuria ( ) if the entry site leaks on their first micturition The entry site must be observed for haemorrhage and urine leakage ( ). If either occurs, pressure must be applied and the child’s doctor informed ( ). The dressing should be removed after 24 hours ( ). Once the site is healed a dressing will no longer be required. The appropriate children’s community nursing team must be informed on admission (...) Suprapubic urinary catheter Suprapubic urinary catheter | Great Ormond Street Hospital Google Tag Manager Navigation Search Search You are here Suprapubic urinary catheter Suprapubic urinary catheter ). The procedure is carried out using an aseptic technique and in children and young people is usually performed under a general anaesthetic. In life threatening situations or acute retention of urine, a suprapubic catheter may however, be inserted under local anaesthetic. The suprapubic catheter

2014 Publication 1593

146. A Randomized Control Trial Comparing Outcome after Stented and Nonstented Anderson-Hynes Dismembered Pyeloplasty. (PubMed)

A Randomized Control Trial Comparing Outcome after Stented and Nonstented Anderson-Hynes Dismembered Pyeloplasty. The aim of the study was to compare the efficacy and postoperative complications of stented and nonstented open pediatric dismembered pyeloplasty for ureteropelvic junction (UPJ) obstruction.A balanced, parallel group, prospective randomized controlled trial comparing stented and nonstented Anderson-Hynes Dismembered Pyeloplasty.It included 42 children who required Anderson-Hynes (...) dismembered pyeloplasty for UPJ obstruction (UPJO). Patients were randomized into stented (double "J" [DJ] stent) and nonstented pyeloplasty groups. The intraoperative and postoperative course was compared. Both groups were analyzed for problems such as dysuria, frequency, pain, hematuria and urinary tract infection, and postoperative renal status.Mann-Whitney U-test, Fisher's exact test, Student's t-tests, and Chi-squared test were used.Surgical duration was significantly shorter for the nonstented group

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2019 Journal of Indian Association of Pediatric Surgeons Controlled trial quality: uncertain

148. Late Effects of Treatment for Childhood Cancer (PDQ®): Health Professional Version

for Childhood Cancer During the past five decades, dramatic progress has been made in the development of curative therapy for pediatric malignancies. Long-term survival into adulthood is the expectation for more than 80% of children with access to contemporary therapies for pediatric malignancies.[ , ] The therapy responsible for this survival can also produce adverse long-term health-related outcomes, referred to as late effects , which manifest months to years after completion of cancer treatment (...) to Support Survivor Care Risk-based screening The need for long-term follow-up for childhood cancer survivors is supported by the American Society of Pediatric Hematology/Oncology, the International Society of Pediatric Oncology, the American Academy of Pediatrics, the Children’s Oncology Group (COG), and the Institute of Medicine. A risk-based medical follow-up is recommended, which includes a systematic plan for lifelong screening, surveillance, and prevention that incorporates risk estimates based

2016 PDQ - NCI's Comprehensive Cancer Database

149. Candida - female genital

(usually white, 'cheese-like', and non-offensive), superficial dyspareunia, and dysuria. Signs may include vulvovaginal inflammation and erythema, vaginal fissuring, and excoriation of the vulva. Microscopy and fungal culture of vaginal secretions to identify yeasts is only recommended for supporting the diagnosis and in cases of severe or recurrent vulvovaginal candidiasis, or treatment failure. Treatment of uncomplicated infection involves: A short course of an intravaginal antifungal (...) (usually white, 'cheese-like', and non-malodorous). Superficial dyspareunia. Dysuria (pain or discomfort during urination). Enquire whether the infection is: An isolated episode, or A recurrence (defined as four or more documented episodes in 1 year, with at least partial resolution of symptoms between episodes), or Treatment failure (failure of symptoms to resolve within 7–14 days of treatment). Ask about any treatments that have been tried already, including over-the-counter treatments. Enquire about

2017 NICE Clinical Knowledge Summaries

150. Herpes simplex - genital

are usually bilateral and develop 4–7 days after exposure to HSV infection. People may complain of dysuria, vaginal or urethral discharge, and systemic symptoms such as fever and malaise. A primary episode can last up to 20 days, and is often more severe than a recurrent episode. Following primary infection, the virus becomes latent in local sensory ganglia. Recurrent genital herpes refers to a recurrence of clinical symptoms due to reactivation of pre-existent HSV infection after a latent period. People (...) of genital herpes and exclude other causes of genital ulceration. Take a brief sexual history , and ask about: Age — there is an increased risk in those aged under 25 years. Previous sexually transmitted infections (STIs). A new sexual partner. More than one sexual partner in the last year. Current and previous sexual partners. Use of barrier contraception. Ask about the onset and duration of symptoms , including: Presence of painful ulcers. Dysuria, vaginal or urethral discharge. Malaise, or fever

2017 NICE Clinical Knowledge Summaries

151. Warts - anogenital

lesions which may be misdiagnosed as anogenital warts include: Pearly penile papules. Benign molluscum contagiosum, skin tags, and seborrhoeic keratoses. Vulval, penile, or anal intraepithelial neoplasia, and frank malignancy. Anogenital condylomata lata of secondary syphilis. Referral to a sexual health specialist is recommended for all people with anogenital warts, especially: Women who are pregnant. Children (the possibility of sexual abuse should be considered). People who are immunocompromised (...) transmitted infection. Ask about: A new sexual partner. More than one sexual partner in the last year. Current and previous sexual partners. Use of barrier contraception. Ask about symptoms : In men, ask about the presence of urethral discharge and dysuria. In women, ask about vaginal discharge and intermenstrual or post-coital bleeding. Distortion of urine flow or bleeding from the urethra (suggesting an intrameatal wart) and bleeding from the anus. Examine the external genitalia , perianal area

2017 NICE Clinical Knowledge Summaries

152. Incontinence - urinary, in women

if the woman: Is aged 45 years and over with unexplained visible haematuria without urinary tract infection, or visible haematuria that is persistent or recurrent after successful treatment of urinary tract infection, or Is aged 60 and over with unexplained non-visible haematuria and dysuria or a raised white cell count on a blood test. Women with stress incontinence should be referred for a trial of at least 3 months' supervised pelvic floor muscle training. If this fails, referral for assessment (...) ) guidance Urinary incontinence and pelvic organ prolapse in women: management [ ]. This CKS topic covers the primary care management of stress urinary incontinence, urgency urinary incontinence (which may be associated with overactive bladder), and mixed urinary incontinence in women. This CKS topic does not cover the specialist management of urinary incontinence in women or the management of urinary incontinence in men, or children. There are separate CKS topics on , , , and . The target audience

2017 NICE Clinical Knowledge Summaries

153. Constella - linaclotide

to be more common in the elderly, leading to its recommendation that prescribers should afford special attention to older patients and assess the medicine’s benefits and risks carefully before and during treatment in this age group. To further elucidate the safety profile of the medicine in this population, the Agency has requested a post-authorisation safety study that specifically includes elderly patients. Regarding children and adolescents, the absence of data led the Agency to restrict its (...) recommended use of linaclotide to adults, especially since GC-C receptor is overexpressed in young children. Specific studies will need to be conducted before a conclusion on safe and effective use in the paediatric population can be made. Linaclotide is expected to offer a useful treatment option for patients with moderate or severe IBS with constipation, once organic diseases have been ruled out and a diagnosis of IBS-C has been established. The Committee’s conclusion that the medicine’s benefits

2012 European Medicines Agency - EPARs

154. Enuresis Alarm

for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: children ages 5-15 years Diagnosis of Primary Monosymptomatic Nocturnal Enuresis >2 wet nights per week Score of 7 or below on questions 1-6 and 9-13 on Vancouver Dysfunctional Elimination Questionnaire Patients/parents compliance in recording data > 50% of nights Exclusion Criteria: Known comorbid conditions: daytime incontinence, anatomic abnormalities (hydronephrosis, VUR), recurrent urinary tract infection, dysuria (...) in children, and use of bedwetting alarms has shown the best long-term success. However, use of alarms is very time-intensive, often taking months before yielding results. Researchers in the division of pediatric urology are initiating a randomized controlled study comparing a standard bedwetting alarm with a newly developed technology, with the hope that the new alarm will result in better, more rapid, and easier treatment for bedwetting. Children between the ages of 5 to 15 years old who have issues

2018 Clinical Trials

155. Use of a Diurnal Indwelling Urethral Catheter to Improve Quality of Life

of a Diurnal Indwelling Urethral Catheter to Improve Quality of Life The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03573726 Recruitment Status : Completed First Posted : June 29, 2018 Last Update Posted : June 29, 2018 Sponsor: Shriners Hospitals for Children Information provided by (Responsible Party (...) ): Eric A Kurzrock, Shriners Hospitals for Children Study Details Study Description Go to Brief Summary: This is an interventional study examining the effects of closed diurnal indwelling catheterization (CDIC) for neurogenic bladder management. Condition or disease Intervention/treatment Phase Spina Bifida Neurogenic Bladder Other: Closed diurnal indwelling catheter (CDIC) Not Applicable Detailed Description: This is an interventional study examining the effects of indwelling diurnal catheter use

2018 Clinical Trials

156. Hematuria in an Adult with Congenital Heart Disease. (PubMed)

Hematuria in an Adult with Congenital Heart Disease. Adults with congenital heart disease (CHD) in the United States now outnumber children with CHD, due in part to the improvement in surgical and medical management. This growing population may present postoperatively to the emergency department (ED) with nonspecific complaints from unforseen complications secondary to cardiac intervention.We describe a 39-year-old male who presented to the ED with hematuria and dysuria after he underwent (...) , the patient's initial presentation of hematuria and dysuria presented a unique diagnostic challenge. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Patients with underlying CHD require emergency physicians to consider a multidisciplinary approach to properly diagnose and facilitate treatment.Copyright © 2017 Elsevier Inc. All rights reserved.

2018 Journal of Emergency Medicine

157. Atopic dermatitis – Treatment with phototherapy and systemic agents

Department of Dermatology, Seattle Children's Hospital, Seattle, Washington , MD (Co-chair) a , x Dawn M. Davis Affiliations Department of Dermatology, Mayo Clinic, Rochester, Minnesota , MD b , x David E. Cohen Affiliations Department of Dermatology, New York University School of Medicine, New York, New York , MD c , x Kelly M. Cordoro Affiliations Department of Dermatology, University of California, San Francisco, California , MD d , x Timothy G. Berger Affiliations Department of Dermatology (...) , x Wynnis L. Tom Affiliations University of San Diego, San Diego, California Division of Pediatric and Adolescent Dermatology, Rady Children's Hospital, San Diego, California , MD m , n , x Hywel C. Williams Affiliations Center of Evidence-based Dermatology, Nottingham University Hospitals National Health Service Trust, Nottingham, United Kingdom , DSc o , x Craig A. Elmets Affiliations Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama , MD p , x Julie Block

2014 American Academy of Dermatology

158. Diagnosis and Treatment Interstitial Cystitis/Bladder Pain Syndrome

the diagnosis, the mean age is older than is typical for the US. A history of a recent culture-proven UTI can be identified on presentation in 18-36% of women, although subsequent cultures are negative. 17, 18 Initially it is not uncommon for patients to report a single symptom such as dysuria, frequency, or pain, with subsequent progression to multiple symptoms. 19, 20 Symptom flares, during which symptoms suddenly intensify for several hours, days, or weeks, are not uncommon. There is a high rate of prior (...) of Children's Hospitals and Related Institutions, and various private data sets between 1994 and 2000 revealed an increase of 29% from $37 to $66 million among persons with a formal diagnosis of IC/BPS. Similarly, the direct annual costs associated with BPS rose from $481 million to $750 million (amounts standardized to 1996-1998 values). 46 Between 1992 and 2001 the rate of visits to physician's offices increased three-fold and the rate of visits to hospital outpatient visits increased two-fold. 46 Only

2014 American Urological Association

159. Joint Hypermobility - Identification and Management of

Joint Hypermobility - Identification and Management of Evidence-Based Care Guideline for Management of Pediatric Joint Hypermobility Guideline 43 Copyright © 2014 Cincinnati Children's Hospital Medical Center, all rights reserved. Page 1 of 48 James M. Anderson Center for Health Systems Excellence Evidence-Based Care Guideline Identification and Management of Pediatric Joint Hypermobility In children and adolescents aged 4 to 21 years old a Publication Date: October 21, 2014 Target Population (...) Inclusions: Children and adolescents: ? With joint hypermobility ? 4 to 21 years old ? Less than 4 years old with a family history of hypermobility Exclusions: Children and adolescents with: ? Greater than mild hypotonia ? Spasticity ? Progressive neuromuscular conditions Target Users Including but not limited to: ? Dentists/Orthodontists ? Nurses ? Nurse Practitioners ? Occupational Therapists ? Physical Therapists ? Psychologists ? Physicians ? Geneticists ? Orthopedists ? Primary Care Physicians

2014 Cincinnati Children's Hospital Medical Center

160. Guideline for consultations requiring sexual history taking

sexual contact (LSC) and number of partners in the last three months Gender of partner(s), anatomic sites of exposure, condom use and any suspected infection, infection risk or symptoms in partners Previous STIs For women: last menstrual period (LMP), contraceptive and cervical cytology history. Blood borne virus risk assessment and vaccination history for those at risk Agree the method of giving results Establish competency, safeguarding children/vulnerable adults Recommend/consider Recognition (...) , contraceptive and cervical cytology history Pregnancy and gynaecological history Blood borne virus risk assessment and vaccination history for those at risk Past medical and surgical history Medication history and history of drug allergies Agree the method of giving results Establish competency, safeguarding children/vulnerable adults Recommend/consider Recognition of gender-based violence/intimate partner violence 1 Alcohol and recreational drug history 2 1 This is a requirement in Scotland

2013 British Association for Sexual Health and HIV

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