How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

702 results for

Dysuria in Children

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

601. Chlamydia trachomatis Full Text available with Trip Pro

factors for genitourinary infections include unprotected sex with multiple partners, lack of condom use, and living in an urban area. Pulmonary infections can occur in infants born to women with active chlamydia infections, although the rate of infection is less than 10%. Ocular infections take the form of conjunctivitis or trachoma, both in adults and children. Trachoma is the primary source of infectious blindness in some parts of rural Africa and Asia and is a that has been targeted by the World (...) (genitals), pulmonary (lungs), and ocular (eyes). Genitourinary cases can include genital discharge, vaginal bleeding, itchiness (pruritus), painful urination (dysuria), among other symptoms. Often, symptoms are similar to those of a . Prevalence [ ] Three times as many women as men are diagnosed with genitourinary C. trachomatis infections. Women aged 15–19 have the highest prevalence, followed by women aged 20–24, although the rate of increase of diagnosis is greater for men than for women. Risk

2012 Wikipedia

602. Safety, Pharmacokinetics and Clinical Activity of Oral Rigosertib in Solid Tumors

prior dose. If two or more patients in any cohort experience DLT, then the maximum tolerated dose (MTD) will have been exceeded and no further dose escalation will occur. The MTD will be established as the immediate prior dosing level Identical rules will be applied to all cohorts of patients recruited to the study. A total of up to 24 patients may be treated at the MTD dose level in order to obtain data on the onset and severity of dysuria symptoms in approximately 12 patients including about 6 (...) in at least 1 dimension with longest diameter equal to or greater than 20 mm using conventional techniques (computed tomography [CT] scan or magnetic resonance imaging [MRI]) or equal to or greater than 10 mm with spiral CT scan. If female, has a negative screening for pregnancy. Women of child-bearing potential and men must agree to use adequate contraception prior to study entry (hormonal or barrier method of birth control; abstinence) and for the duration of study participation. Should a woman become

2010 Clinical Trials

603. Management of Urinary Tract Infections in Primary Care Facilities.

Ages Eligible for Study: 16 Years to 55 Years (Child, Adult) Sexes Eligible for Study: Female Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Females 16-55 years Dysuria Increased frequency of urination Exclusion Criteria: Pregnant Breastfeeding child < 1 month of age Diabetes Kidney disease Fever Poor general condition Backpain Abdominal pain Increased amount of vaginal secretions Vaginal itching or pain Urinary tract infection in the last four weeks Use of urinary catheter in the last

2010 Clinical Trials

604. Risk factors of HIV vertical transmission in a cohort of women under a PMTCT program at three peri-urban clinics in a resource-poor setting Full Text available with Trip Pro

Risk factors of HIV vertical transmission in a cohort of women under a PMTCT program at three peri-urban clinics in a resource-poor setting To identify the risk factors of HIV vertical transmission in pregnant women.Observational cohort study. Between 2002 and 2003, 479 HIV-infected pregnant women in a PMTCT (prevention of the mother-to-child transmission) program were followed up with their infants at delivery, until 15 months with infant HIV testing.Of these 281 infants had a definitive HIV (...) result by 15 months of age, and 31.7% of the infants become HIV infected. In univariate analysis the risk factor identified were presence of vaginal discharge, genital itchiness, genital ulcers, dysuria, abnormal breast and vaginal infections (Trichomonas, Bacteria vaginosis and Candida) in the mother at enrolment. In multivariate analysis vaginal infections risk ratio (RR) 1.72(1.03-2.88) and abnormal breast RR 4.36(2.89-6.58) were predictors of HIV vertical transmission.There is need to screen

2010 Journal of Perinatology

605. Mutations in HPSE2 cause urofacial syndrome. Full Text available with Trip Pro

Mutations in HPSE2 cause urofacial syndrome. Urinary voiding dysfunction in childhood, manifesting as incontinence, dysuria, and urinary frequency, is a common condition. Urofacial syndrome (UFS) is a rare autosomal recessive disease characterized by facial grimacing when attempting to smile and failure of the urinary bladder to void completely despite a lack of anatomical bladder outflow obstruction or overt neurological damage. UFS individuals often have reflux of infected urine from

2010 American Journal of Human Genetics

606. Nonoperative management of symptomatic urachal anomalies. (Abstract)

anomalies was performed from January 2002 to March 2008. Children with a draining umbilicus and no radiographic or surgical confirmation of a urachal anomaly were excluded.Fifteen patients with symptomatic urachal anomalies were identified. The average age was 3.5 years (4 weeks to 14 years). Symptoms included umbilical drainage (n = 10), abdominal pain (n = 6), omphalitis (n = 4), intraabdominal mass (n = 3), dysuria (n = 1), recurrent urinary tract infections (n = 1), and fever (n = 4). The diagnosis

2010 Journal of Pediatric Surgery

607. Dose Exploring and Setting Study for Tolvaptan to Treat Hepatic Cirrhosis With Ascites

: Hepatic encephalopathy (Coma scale Note 1) grade 2 or higher); Malignant ascites; Uncontrolled spontaneous bacterial peritonitis; Patients are likely to experience alimentary tract hemorrhage during the trial; Heart failure (NYHA cardiac function scale Note 2) stages 3 and 4); Anuria (daily urine volume below 100mL); Dysuria resulting from urethral stricture, calculus and tumors. Patients with the following medical history: Alimentary tract hemorrhage within 10 days prior to screening; Cerebrovascular (...) accident within 1 month prior to screening; Gout attack within 1 month prior to screening; Past allergy or hypersensitive reactions to benzodiazepines (e.g. benazepril hydrochloride) Systolic pressure below 90mmHg at screening; Patients with the following abnormalities in laboratory examinations at screening: Serum creatinine exceeds 2.5X upper limits of normal, serum Na+>145mmol/L (or exceeds upper limits of normal), serum K+>5.5mmol/L, uric acid>8.0mg/dL (476μmol/L), Child-pugh scale greater than 12

2010 Clinical Trials

608. Multiple-dose Pharmacokinetics Study of Tolvaptan Tablets in Chinese Patients With Hepatocirrhosis

actions and safety of Tolvaptan tablets administered orally (15 mg daily) for consecutively 7 days in Chinese adult patients with confirmed Child-Pugh Class B(score 7-9) hepatocirrhosis (accompanied by ascites). Trial Design: Open, single-center, multi-dose pharmacokinetics study Study population: Chinese adult patients with confirmed Child-Pugh Class B (score 7-9) hepatocirrhosis (accompanied by ascites) Dosage and mode of administration of investigational product: Oral administration of 1 tablet (...) ); Malignant ascites; Spontaneous bacterial peritonitis; Likely to have gastrointestinal bleeding during the study period; Heart failure (NYHA Note 2 Class Ⅲ andⅣ); Anuria (daily urine output below 100mL); Dysuria induced by urinary tract stenosis, calculus, or tumor. Patients with any of the following history: With gastrointestinal bleeding within 10 days prior to screening; With cerebrovascular accident within 1 month prior to screening; With gout attack within 1 month prior to screening; With allergy

2010 Clinical Trials

609. Efficacy of Combination Therapies for Gonorrhea Treatment

). Clinical Profile of Treatment Failures. [ Time Frame: 10-17 days ] For treatment failures (i.e., participants with positive culture at cervix/urethra 10-17 days after treatment), number participants with clinical symptoms (vaginal/urethral discharge, dysuria, dyspareunia) at 10-17 days. Resolution of Symptoms and Signs (Clinical Cure) [ Time Frame: 10-17 days after treatment. ] Number of participants whose gonorrhea-related symptoms (e.g. vaginal/urethral discharge, dysuria, dyspareunia) present (...) or not associated with study product. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 15 Years to 60 Years (Child

2009 Clinical Trials

610. Anxiety and Recurrent Abdominal Pain in Children

and tolerability. Condition or disease Intervention/treatment Phase Abdominal Pain Anxiety Drug: Citalopram Phase 2 Phase 3 Detailed Description: This study aims to determine the relative efficacy, tolerability, and safety of the citalopram in the treatment of pediatric functional recurrent abdominal pain (FAP) in children and adolescents ages 7 to 18 years, inclusive. The goal is to recruit and randomize 100 subjects to citalopram or placebo. Secondary aims include to determine if citalopram is superior (...) on the Children's Global Assessment Scale Residing with a primary caretaker (i.e., parent, legal guardian, relative functioning as a parent, or foster parent) who has known the child well for at least 6 months prior to study entry and has legal authority to consent to participation. Exclusion Criteria: Physical disease sufficient to explain the subjective distress and functional impairment suffered by the subject. FAP with atypical features: Abnormal abdominal or rectal examination GI bleeding (i.e., hematest

2009 Clinical Trials

611. New Tissue Bulking Agent (Polyacrylate Polyalcohol) for Treating Vesicoureteral Reflux: Preliminary Results in Children. (Abstract)

New Tissue Bulking Agent (Polyacrylate Polyalcohol) for Treating Vesicoureteral Reflux: Preliminary Results in Children. We report the preliminary results of endoscopic treatment of vesicoureteral reflux in children using polyacrylate polyalcohol copolymer.We performed a prospective multicenter review of pediatric patients treated with subureteral injection of a new nonabsorbable substance. Only patients with 1 year of followup were included.A total of 83 patients underwent injection (...) 16 to 24). Complications after injection included dysuria in 6 patients (9.8%), fever in 3 (4.9%) and lumbar pain in 4 (6.6%). Reflux was eliminated in 78 renal units (88.6%), decreased to grade I in 6 (6.8%) and persisted in 4 (4.5%). Ureteral obstruction developed in 1 patient and was treated operatively. Overall success rate was 83.6%.Polyacrylate polyalcohol copolymer can be used to treat vesicoureteral reflux with comparable efficacy to other substances currently used, with a low rate

2009 Journal of Urology

612. Recurrent Abdominal Pain in Childhood Urolithiasis. (Abstract)

Recurrent Abdominal Pain in Childhood Urolithiasis. Our goal was to establish the clinical presentation and features of pain attacks in children with recurrent abdominal pain (RAP) and urolithiasis.We compared the rate of previous appendectomy among 100 consecutive patients with that of 270 control subjects. We also compared the frequency of pain attacks with that reported by children with functional or organic gastrointestinal RAP.Fifty-three patients had no history of dysuria or gross (...) should be considered in children with RAP who have a family history of urolithiasis and/or infrequent pain attacks, even when dysuria and hematuria are lacking, and in younger children even when pain is not lateral.

2009 Pediatrics

613. Reports of Repetitive Penile-Genital Penetration Often Have No Definitive Evidence of Penetration. Full Text available with Trip Pro

Reports of Repetitive Penile-Genital Penetration Often Have No Definitive Evidence of Penetration. The goals were to evaluate the association of definitive hymenal findings with the number of reported episodes of penile-genital penetration, pain, bleeding, dysuria, and time since assault for girls presenting for nonacute, sexual assault examinations.Charts of all girls 5 to 17 of age who provided a history of nonacute, penile-genital, penetrative abuse were reviewed. Interviews and examinations (...) occurred over a 4-year period at a children's advocacy center. Characteristics of the histories provided by the subjects were examined for associations with definitive findings of penetrative trauma.Five hundred six patients were included in the study. Of the 56 children with definitive examination results, 52 had no history of consensual penile-vaginal intercourse and all were > or =10 years of age. Analysis was unable to detect an association between the number of reported penile-genital penetrative

2009 Pediatrics

614. Pediatric Urolithiasis: Clinical Predictors in the Emergency Department. (Abstract)

Pediatric Urolithiasis: Clinical Predictors in the Emergency Department. The objective of this study was to identify factors that predict the presence of urolithiasis detected with unenhanced computed tomography (UCT) in children.A retrospective study of all subjects <21 years of age who presented to the emergency department at Akron Children's Hospital and underwent UCT of the abdomen between January 2002 and December 2005 was performed. Demographic, clinical, diagnostic, treatment (...) %) were renal, and 4 (3.6%) were in the bladder. Among children who did not have a stone identified through UCT, 23 cases (10%) of potentially significant, alternative diagnoses were identified. A history of urolithiasis, a history of nausea and vomiting, the presence of flank pain on examination, and >2 red blood cells per high-power field in urine microscopy were positively associated with urolithiasis. A history of fever or dysuria and costovertebral angle tenderness on physical examination were

2009 Pediatrics

615. Long-Term Outcomes of the Neobladder in Pediatric Continent Urinary Reconstruction. (Abstract)

Long-Term Outcomes of the Neobladder in Pediatric Continent Urinary Reconstruction. In rare instances when native bladder tissue is either unsuitable or unavailable a continent neobladder may be an option for pediatric lower urinary tract reconstruction. We report our long-term outcomes and experience in this challenging patient population.A retrospective cohort study was performed of all patients who underwent creation of a neobladder at 2 pediatric institutions. Patient demographics, surgical (...) obstruction (4), bladder perforation (4) and pelvic lymphocele (1). Five patients had difficulty with catheterization due to stomal stenosis. Gross hematuria with clots developed in 1 patient with anuria who had a gastroileal neobladder and was awaiting renal transplantation. No other patient with a gastric component had the hematuria-dysuria syndrome. Five patients had end stage renal disease and subsequently underwent successful renal transplantation. No upper urinary tract deterioration was observed

2009 Journal of Urology

616. Conservative Management of Pediatric Nephrolithiasis Caused by Melamine-Contaminated Milk Powder. (Abstract)

Conservative Management of Pediatric Nephrolithiasis Caused by Melamine-Contaminated Milk Powder. In this article we report our experience with the diagnostic screening and management of children with melamine-induced nephrolithiasis.A total of 1091 children younger than 4 years who had been exposed to melamine-contaminated formula from September 17 to October 12, 2008, were screened for nephrolithiasis at the department of pediatrics at Shenzhen Nanshan Hospital in China. During the clinical (...) infusion of fluids, urinary alkalinization, increased water consumption, and diuresis.Of the 1091 children screened, 12 (1.1%) were diagnosed with kidney stones. They had been exposed to the contaminated milk from 1 to 24 months. Eleven (91.7%) of these 12 patients had consumed milk with a high level of melamine content (955-2563 ppm); 1 patient (8.3%) had consumed milk with a low-level melamine content (6.2-17.0 ppm). Six patients exhibited dysuria; the remaining 6 patients were asymptomatic. All 12

2009 Pediatrics

617. Urinary tract infection in under 16s: diagnosis and management

there will be a small number of false negative results; therefore clinicians should use clinical criteria for their decisions in cases where urine testing does not support the findings. [2007] [2007] 1.1.5.2 Refer all infants under 3 months with a suspected UTI (see table 1) to paediatric specialist care, and send a urine sample for urgent microscopy and culture manage in line with the NICE guideline on fever in under 5s. [2017] [2017] 1.1.5.3 Use dipstick testing for infants and children 3 months or older (...) treatment should be started if clinically UTI The infant or child should be regarded as not having UTI Urinary tract infection in under 16s: diagnosis and management (CG54) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 8 of 231.1.6 1.1.6 Indication for culture Indication for culture 1.1.6.1 Urine samples should be sent for culture: in infants and children who are suspected to have acute pyelonephritis/upper urinary

2007 National Institute for Health and Clinical Excellence - Clinical Guidelines

618. urinary schistosomiasis

weeks after infection is the first sign of established disease in severe cases, the whole urine sample can be dark coloured. maybe confused with menses in girls dysuria increased frequency of micturition late manifestations proteinuria (often nephrotic syndrome) bladder calcification ureteric obstruction secondary bacterial infection in the urinary tract renal colic hydronephrosis renal failure (1,2,3) In children, structural abnormalities of the urinary tract may be seen in some instances (1 (...) , and increased risk of abortion advances forms of the genital tract lesionscan increase transmission of HIV (3) In men can present with haematospermia, orchitis, prostatitis, dyspareunia, and oligospermia. resolve more readily after antischistosomal treatment than do those of female genital schistosomiasis (3) Note: dysuria and haematuria occur in early and late disease Reference: (1) (2) (3) Links: General Practice Notebook General Practice Notebook The information provided herein should not be used

2010 GP Notebook

619. haematobium schistosomiasis

weeks after infection is the first sign of established disease in severe cases, the whole urine sample can be dark coloured. maybe confused with menses in girls dysuria increased frequency of micturition late manifestations proteinuria (often nephrotic syndrome) bladder calcification ureteric obstruction secondary bacterial infection in the urinary tract renal colic hydronephrosis renal failure (1,2,3) In children, structural abnormalities of the urinary tract may be seen in some instances (1 (...) , and increased risk of abortion advances forms of the genital tract lesionscan increase transmission of HIV (3) In men can present with haematospermia, orchitis, prostatitis, dyspareunia, and oligospermia. resolve more readily after antischistosomal treatment than do those of female genital schistosomiasis (3) Note: dysuria and haematuria occur in early and late disease Reference: (1) (2) (3) Links: General Practice Notebook General Practice Notebook The information provided herein should not be used

2010 GP Notebook

620. Bridion (sugammadex)

/59 One-hundred twenty subjects were enrolled, six per dose group and per age group. The dose groups were 0.5, 1.0, 2.0, or 4.0 mg/kg Bridion or placebo. The age groups were: Infants (28 days - 23 month), children (2-11 years), adolescents (12 – 17 years) and adults (18 -65 years). A total of 91 subjects (8 infants, 24 children, 31 adolescents, and 28 adults) received a single, bolus, intravenous dose of Bridion (0.5, 1, 2, or 4 mg/kg) or placebo. A total of 90 subjects completed the trial (...) Mean (SD) 29.5 (8.4) 3.8 (1.1) 1.6 (0.3) 1.3 (0.3) 1.4 (0.4) Median 28.5 4.2 1.7 1.2 1.4 Min. – max. 19.6 – 44.0 2.3 – 4.8 1.2 – 2.0 0.9 – 1.6 1.0 – 2.0 It was concluded that for children, adolescents and adults a clear dose-response relationship was found. On the contrary, in infants, the mean time to recovery of the T4/T1 ratio to 0.9 markedly decreased with increasing dose of sugammadex. However no plateau, i.e. no limit of recovery was reached and no dose-response effect could be demonstrated

2008 European Medicines Agency - EPARs

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>