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Dysuria in Children

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241. Prevalence of Female Circumcision Among Young Women in Beni-Suef, Egypt

this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: 12 Years to 25 Years (Child, Adult) Sexes Eligible for Study: Female Accepts Healthy Volunteers: No Sampling Method: Probability Sample Study Population The urban Metropolitan of Beni-Suef City was classified according to the socioeconomic level of its quarters to low, middle, and high levels. Out of each level (...) Posted: December 22, 2017 Last Verified: December 2017 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: No Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by Nesreen Abdel Fattah Abdullah Shehata, Beni-Suef University: Female circumcision, Young Women, Dysmenorrhea,Dysuria

2017 Clinical Trials

242. Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults

of an indwelling catheter ii. >100 mL of residual urine after voiding iii. Neurogenic bladder iv. Obstructive uropathy due to nephrolithiasis, tumor or fibrosis v. Azotemia due to intrinsic renal disease vi. Urinary retention in men possibly due to benign prostatic hypertrophy vii. Surgically modified or abnormal urinary tract anatomy At least two of the following signs or symptoms: Rigors, chills or fever/hypothermia Flank pain or pelvic pain Nausea or vomiting Dysuria, urinary frequency or urinary urgency (...) , others) Chronic indwelling catheters or stents Ileal loops or vesico-urethral reflux Recent trauma to the pelvis or urinary tract within the prior 30 days History of seizures Patients with a history of blood dyscrasias Patients with a history of uric acid kidney stones Patients with acute gouty attack Patients on chronic methotrexate therapy Females of child-bearing potential who are unable to take adequate contraceptive precautions, have a positive pregnancy test result within 24 hours of study

2017 Clinical Trials

243. Profile of sexual and genitourinary treatment-emergent adverse events associated with atomoxetine treatment: a pooled analysis. (Abstract)

Profile of sexual and genitourinary treatment-emergent adverse events associated with atomoxetine treatment: a pooled analysis. Attention-deficit hyperactivity disorder (ADHD) is a neuropsychiatric disorder that begins in childhood. Atomoxetine is a selective inhibitor of the presynaptic norepinephrine transporter. Several studies have demonstrated the safety and efficacy of atomoxetine in the treatment of ADHD.The objective of this analysis was to provide additional information (...) male patients reported relatively more sexual and GU TEAEs when taking atomoxetine compared with placebo, with libido decreased (4.6 vs. 3.0 %), dysuria (3.7 vs. 1.5 %), urinary hesitation (6.9 vs. 2.4 %), urine flow decreased (2.5 vs. 0.6 %), ejaculation disorder (2.8 vs. 1.1 %) and erectile dysfunction (8.0 vs. 1.9 %) being the most common. The time to onset of the most common TEAEs in adult male patients tended to occur relatively early in dosing: within the first 2 weeks for GU TEAEs

2017 Drug Safety

244. Factors associated with Schistosomiasis outbreak at Omindamba primary school, Omusati region, Namibia: a case-control study, March 2016 (Full text)

Med J 101517926 IM Abdominal Pain etiology parasitology Adolescent Animals Case-Control Studies Child Disease Outbreaks Dysuria etiology parasitology Female Health Education methods Hematuria etiology parasitology Humans Male Namibia epidemiology Risk Factors Schistosoma haematobium isolation & purification Schistosomiasis haematobia diagnosis epidemiology prevention & control Students Young Adult 2016 12 21 2017 08 02 2018 4 4 6 0 2018 4 4 6 0 2018 8 3 6 0 epublish 29610650 10.11604/pamj

2017 The Pan African medical journal PubMed abstract

245. Safety Study of BMX-001 (Radio-protector) in Patients With Newly Diagnosed Anal Cancer

rectal pain per CTCAE 4.0 Impact of study treatment on bowel movements [ Time Frame: Pre-treatment baseline, once every 5 fractions of RT and then 1, 4 and 10 months post RT ] To examine acute grade 3 diarrhea per CTCAE 4.0 Impact of study treatment on acute dysuria [ Time Frame: Pre-treatment baseline, once every 5 fractions of RT and then 1, 4 and 10 months post RT ] To examine acute grade 3 dysuria per CTCAE 4.0 Impact of study treatment on acute hematuria [ Time Frame: Pre-treatment baseline (...) Negative pregnancy test for women of child-bearing potential within 48 hours prior to first dose of BMX-001 Women of childbearing potential and male participants must agree to use a medically effective means of birth control throughout their participation in the treatment phase of the study and until 12 months following the last study treatment PET/CT/ pelvic MRI done within 8 weeks of trial initiation Exclusion Criteria: Breast-feeding Active infection requiring IV antibiotics 7 days before enrollment

2017 Clinical Trials

246. Bladder and Other Urothelial Cancers Screening (PDQ®): Health Professional Version

Information Summari...] Review Childhood Bladder Cancer Treatment (PDQ®): Health Professional Version PDQ Pediatric Treatment Editorial Board. PDQ Cancer Information Summaries. 2002 [PDQ Cancer Information Summari...] Review Neuroblastoma Screening (PDQ®): Health Professional Version PDQ Screening and Prevention Editorial Board. PDQ Cancer Information Summaries. 2002 [PDQ Cancer Information Summari...] Review Thyroid Cancer Screening (PDQ®): Health Professional Version PDQ Screening and Prevention (...) symptoms include dysuria, urinary frequency or urgency, and less commonly, flank pain secondary to obstruction, and pain from pelvic invasion or bone metastases. Diagnosis and staging usually begin with cystoscopy. Full evaluation of the upper and lower urinary tract is required.[ ] Histopathology More than 90% of bladder cancers diagnosed in the United States are pure TCCs or TCCs mixed with other histologies, primarily SCC, adenocarcinoma, or both. An additional 3% to 4% are pure SCCs, which

2016 PDQ - NCI's Comprehensive Cancer Database

247. Postrenal Failure

Postrenal Failure Postrenal Failure Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Postrenal Failure Postrenal Failure Aka: Postrenal (...) that results in dilatation of the renal pelvis and calyces. It is caused by obstruction of urine flow, nephrolithiasis, or vesicoureteral reflux. Signs and symptoms include flank pain, nausea, vomiting, fever, and dysuria. Definition (NCI_NCI-GLOSS) Abnormal enlargement of a kidney, which may be caused by blockage of the ureter (such as by a kidney stone) or chronic kidney disease that prevents urine from draining into the bladder. Definition (CSP) distention of the pelvis and calices of the kidney

2018 FP Notebook

248. Vulvar Lichen Sclerosus

Vulvar Lichen Sclerosus Vulvar Lichen Sclerosus Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Vulvar Lichen Sclerosus Vulvar Lichen (...) subepithelial fibrosis. Clinical manifestations include pruritus, dysuria, and dyspareunia. Definition (MSH) Atrophy and shriveling of the SKIN of the VULVA that is characterized by the whitish LICHEN SCLEROSUS appearance, inflammation, and PRURITUS. Concepts Disease or Syndrome ( T047 ) MSH ICD10 SnomedCT 73057003 , 156019006 , 198379009 , 266666006 , 26348009 , 198380007 English Vulvae, Kraurosis , Leukoplakic vulvitis , VULVAL LEUKOPLAKIA , kraurosis of vulva (diagnosis) , kraurosis of vulva

2018 FP Notebook

249. Icatibant (Firazyr)

times/day, then decrease by = 50% every = 1-3 month (may increase by = 200 mg if attack occurs) *Labeling states safety and efficacy in children 0 to 12 years of age have not been established; **Labeling states safety and effectiveness not established in neonates, infants, or children, with three subjects studied under the age of 18 years in single efficacy trial; IV = intravenous; SC = subcutaneous Of note, severe hypersensitivity reactions, including anaphylaxis, are listed in the Warnings (...) for Adverse Events 132 7.5.2 Time Dependency for Adverse Events 132 7.5.3 Drug-Demographic Interactions 132 7.5.4 Drug-Disease Interactions 134 7.5.5 Drug-Drug Interactions 135 7.6 Additional Safety Evaluations 135 7.6.1 Human Carcinogenicity 135 7.6.2 Human Reproduction and Pregnancy Data 135 7.6.3 Pediatrics and Assessment of Effects on Growth 136 Reference ID: 2978223Clinical Review Brian Oscar Porter, M.D., Ph.D., M.P.H. NDA 22-150 Icatibant 4 7.6.4 Overdose, Drug Abuse Potential, Withdrawal

2011 FDA - Drug Approval Package

250. Methylthioninium chloride Proveblue

literature substituting all non-clinical tests and clinical studies. The applicant applied for the following indication: Treatment of medicinal and chemical products- induced methaemoglobinaemia. Methylthioninium chloride Proveblue is indicated in adults and children above the age of 3 months. Page 4/47 Information on Paediatric requirements Not applicable Scientific Advice: The applicant received Scientific Advice from the CHMP on 25 June 2009. The Scientific Advice pertained to non-clinical (...) and the gastric pH in infants encourages the conversion of nitrates into nitrites. Furthermore, the frequency of poisonings is two to four times higher for children under four years than for adults. The elderly are subject to methaemoglobinaemia when suffering from anaemia or cardiopulmonary disorders, especially since Diaphorase I (NADH) is less responsive. Acute methaemoglobinaemia may be life-threatening and requires an emergency treatment. Treatment of methaemoglobinaemia relies on rapid identification

2011 European Medicines Agency - EPARs

251. Ezogabine (Potiga)

Evaluations 96 7.6.1 Human Carcinogenicity 96 7.6.2 Human Reproduction and Pregnancy Data 96 7.6.3 Pediatrics and Assessment of Effects on Growth 97 7.6.4 Overdose, Drug Abuse Potential, Withdrawal and Rebound 97 7.7 Additional Submissions / Safety Issues 97 8 POSTMARKET EXPERIENCE 97 9 APPENDICES 98 9.1 Literature Review/References 98 9.2 Labeling Recommendations 98 9.3 Advisory Committee Meeting 101 Reference ID: 2957637Clinical Review Steven T. Dinsmore NDA 22345 Potiga / ezogabine 6 Table of Tables (...) events of dysuria. These events occurred in healthy volunteers and are consistent with prior observations in ezogabine treatment but also demonstrate the events of voiding dysfunction are not restricted to the epilepsy population. Psychotic symptoms: Two patients in the open label extension studies had SAEs due to psychotic symptoms, in one patient there was a positive dechallenge. In the clinical pharmacology studies one healthy control subject had an SAE due to psychotic symptoms (covered fully

2011 FDA - Drug Approval Package

252. Postpartum Nursing Care Pathway

Infant Feeding – Breastfeeding 39 Infant Feeding – Formula Feeding 42 Lifestyle Activities/Rest 43 Healthy Eating 45 Smoking and Use of Drugs/Substances 46 Safe Home Environment 48 Glossary of Abbreviations 49 References & Endnotes 49 Revision Committee 53 Perinatal Services BC Obstetrics Guideline 20 Postpartum Nursing Care Pathway March 2011 While every attempt has been made to ensure that the information contained herein is clinically accurate and current, Perinatal Services BC acknowledges (...) In certain circumstances (such as maternal mental health or child maltreatment) nursing judgment and/or reporting requirements may override a woman’s decision Introduction3 Obstetrics Guideline 20: Postpartum Nursing Care Pathway Referring to a Primary Health Care Provider (PHCP) Prior to referring to a Primary Health Care Provider (PHCP) an appropriate postpartum nursing assessment will be performed. This may need to be specific or global (physical, emotional, & psychosocial health, lear ning needs

2011 British Columbia Perinatal Health Program

253. Trobalt - retigabine

No. EMEA/H/C/001245 Assessment Report as adopted by the CHMP with all information of a commercially confidential nature deleted Medicinal product no longer authorised Assessment report EMA/407212/2014 Page 2/96 Table of contents 1. Background information on the procedure 5 1.1. Submission of the dossier 5 Information on Paediatric requirements 5 Information relating to orphan market exclusivity 5 Scientific Advice 5 Licensing status 6 1.2. Steps taken for the assessment of the product 6 2. Scientific (...) ITT Intent-to-treat LEV Levetiracetam LTG Lamotrigine MES Maximal Electroshock MR Modified release MS Mass Spectroscopy MTD Maximum Tolerated Dose n/a not applicable NAMR N-acetyl metabolite NAT N-Acetyl Transferase NDA New Drug Application NOAEL No observed adverse effect level NTEL No-Toxic-Effect Level PB Phenobarbital PCC Potential Clinical Concern PCT Pivotal Controlled Trials PD Pharmacodynamic PDCO Paediatric Committee PEC Predicted Environmental Concentration Medicinal product no longer

2011 European Medicines Agency - EPARs

254. Jevtana - cabazitaxel

related to body surface area and tumour type. Elderly In the population pharmacokinetic analysis in 70 patients of 65 years and older (57 from 65 to 75 and 13 patients above 75), no age effect on the pharmacokinetics of cabazitaxel was observed. CHMP assessment report EMA/CHMP/782336/2010 Page 32/66 Paediatric patients Safety and effectiveness of JEVTANA have not been established in children and adolescents below 18 years of age. Hepatic impairment No formal studies in patients with hepatic impairment (...) based on applicants’ own tests and studies. Information on Paediatric requirements Pursuant to Article 7 of Regulation (EC) No 1901/2006, the application included an EMA Decision P/146/2009 for the following conditions: ? treatment of prostate carcinoma on the granting of a class waiver. Information relating to orphan market exclusivity Similarity Not applicable. Market Exclusivity Not applicable. Scientific Advice: The applicant received Scientific Advice from the CHMP on 19 March 2009

2011 European Medicines Agency - EPARs

255. Myasthenic crisis

Myasthenic crisis Myasthenic crisis - First10EM Search Myasthenic crisis by | Published - Updated | A 50 year old woman presents with a 2 day history of dysuria, for which she was started on ciprofloxacin last night. Since this morning, she has become increasingly weak, and now finds it impossible to get out of bed. She called 911 when she noticed she couldn’t catch her breath. She wonders whether this might be related to her myasthenia gravis… Introduction Myasthenic crisis is a clinical (...) of the Articles of the Month (released well into the new year because of the craziness of […] Share this: Like this: Like Loading... Published Does IV fluid rate or tonicity contribute to the rate of cerebral edema in pediatric DKA? Share this: Like this: Like Loading... Published A brief summary of the initial resuscitation of a patient with isoniazid toxicity Share this: Like this: Like Loading... Leave a Reply One thought on “ Myasthenic crisis ” Post navigation Previous post Next post © 2019 – All rights

2018 First10EM

256. Vaginal Cancer Treatment (PDQ®): Health Professional Version

third of the vagina. In women who had not previously undergone hysterectomy, upper vaginal lesions were found in 17 of 50 women (34%). Clinical Features Although early vaginal cancer may not cause noticeable signs or symptoms, possible signs and symptoms of vaginal cancer include the following: Metrorrhagia. Dyspareunia. Pelvic pain. Vaginal mass. Dysuria. Constipation. Diagnostic Evaluation The following procedures may be used to diagnose vaginal cancer: History and physical exam. Pelvic exam (...) physical examination and assessment of new symptoms. Therefore, outside the investigational setting, imaging procedures may be reserved for patients in whom physical examination or symptoms raise clinical suspicion of a recurrence or progression. Related Summaries Other PDQ summaries containing information related to vaginal cancer include the following: . (childhood ). References Eifel PJ, Klopp AH, Berek JS, et al.: Cancer of the cervix, vagina, and vulva. In: DeVita VT Jr, Lawrence TS, Rosenberg SA

2015 PDQ - NCI's Comprehensive Cancer Database

257. Bladder Cancer Treatment (PDQ®): Health Professional Version

is thought to play a key role in carcinogenesis in these settings. Clinical Features Bladder cancer typically presents with gross or microscopic hematuria. Less commonly, patients may complain of urinary frequency, nocturia, and dysuria, symptoms that are more common in patients with carcinoma in situ . Patients with upper urinary tract urothelial carcinomas may present with pain resulting from obstruction by the tumor. Urothelial carcinomas are often multifocal—the entire urothelium needs

2015 PDQ - NCI's Comprehensive Cancer Database

258. Prevention and treatment of HIV and other sexually transmitted infections among men who have sex with men and transgender people

recommendation, low quality of evidence 20. Offering periodic serological testing for asymptomatic syphilis infection to MSM and transgender people is strongly recommended over not offering such screening. Strong recommendation, moderate quality of evidence 21. MSM and transgender people should be included in catch-up HBV immunization strategies in settings where infant immunization has not reached full coverage. In line with existing WHO guidance16 1. BACKGROUND Epidemiology Since the beginning

2011 World Health Organisation HIV Guidelines

259. UTI: More than you ever wanted to know

on diagnosis of UTI is very difficult to interpret. Because, what is the definition of a UTI? It’s not consistent across studies. There is no clear gold standard. It is often defined based on a culture, although a positive culture has many different definitions as well. Unfortunately, we know that people, especially children and the elderly, can have positive urine cultures without having UTIs. UTIs also occur without a positive culture. So culture both over and under calls UTI and can’t be used as a true (...) . History and Physical Self diagnosis is pretty accurate. If a woman has had a previous UTI and now has similar symptoms, that has a positive LR of 4.0 and is about 90% accurate for UTI. (Lane 2011; Bent 2002) A women telling you that she has a UTI is just as accurate as a positive dipstick (both with positive likelihood ratios of 4). (Aubin 2007) It’s not clear if these two pieces of information are additive, but there is reason to think they wouldn’t be: women without typical symptoms such as dysuria

2017 First10EM

260. Macroscopic Hematuria and a Bladder Mass: Eosinophilic Cystitis in a 7-Year-Old Boy (Full text)

Macroscopic Hematuria and a Bladder Mass: Eosinophilic Cystitis in a 7-Year-Old Boy We report a case of eosinophilic cystitis in a 7-year-old boy with a history of atopic symptoms, with focus on the radiological findings. He presented with hematuria and dysuria and ultrasonography (US) showed irregular bladder wall thickening resembling a bladder mass. CT urography did not characterize the lesion any further and showed no local or distant spread. Biopsies revealed eosinophilic cystitis (...) , a benign inflammatory condition. We found that US characterized the lesion at least as well as CT and should be the first choice of imaging. When staging is considered before biopsy, MRI should be preferred to CT. There are no specific radiological signs of eosinophilic cystitis. On follow-up, US was a safe, cost-effective imaging modality, but findings should be interpreted in a clinical context. In a child with hematuria and a bladder mass, eosinophilic cystitis is a relevant but rare differential

2016 Case Reports in Radiology PubMed abstract

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