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All-cause and cause-specific mortality from restrictive and obstructive spirometric patterns in Chinese adults with and without dyspnea: Guangzhou Biobank Cohort Study. To study whether abnormal spirometric patterns were associated with differential mortality in Chinese adults with and without dyspnea.Guangzhou Biobank Cohort Study (GBCS) participants were classified by spirometric patterns and presence of dyspnea into 6 groups: normal spirometry (NS), restriction on spirometry (ROS (...) associated with increased risks of all-cause (aHRs 1.46 (95% CI 1.28-1.66) and 1.81 (95% CI 1.33-2.47)) and cardiovascular mortality (aHRs 1.89 (95% CI 1.55-2.31) and 1.85 (95% CI 1.12-3.03)), but not of lung cancer mortality (aHRs 1.33 (95% CI 0.91-1.94) and 1.35 (95% CI 0.49-3.70)); AO with and without dyspnea were associated with increased risks of all-cause (aHRs 1.59 (95% CI 1.36-1.86) and 2.36 (95% CI 1.77-3.15)), cardiovascular (aHRs 1.43 (95% CI 1.08-1.90) and 1.61 (95% CI 0.91-2.82)) and lung
Unraveling the Causes of Unexplained Dyspnea: The Value of Exercise Testing. Unexplained dyspnea presents a significant diagnostic challenge. Dyspnea arises when inspiratory neural drive (IND) to the respiratory muscles is increased and the respiratory system fails to meet this increased demand. Cardiopulmonary exercise testing (CPET) is a valuable tool to unravel the causes of exertional dyspnea in the individual. Moreover, analysis of breathing pattern, operating lung volumes and flow-volume
Castleman's disease as an unusual cause for dysphagia and dyspnea in a pediatric patient. Castleman's disease is a very rare entity in pediatric population and its presentation in the neck is scarcely described in the literature. We present the case of a 10-year-old-girl with an expanding neck mass over several months causing dysphagia and dyspnea. Surgical excision of the mass was performed and the analysis revealed unicentric Castleman's Disease. This is the second largest reported case
USERS 2 METHODS 2 Literature Search Strategy 2 Study Selection Criteria and Process 3 Guideline Assessment 3 RESULTS AND DISCUSSION 4 Dyspnea Definition and Background 4 Overview of Search Results 4 Guidelines Focused on Dyspnea or Symptom Management 5 Guidelines Focused on Specific Cancers 6 Treatment-Related Dyspnea 8 Non-Cancer Causes of Dyspnea 8 Dyspnea Assessment and Guideline/Algorithm Implementation 9 SUMMARY AND SUGGESTIONS FOR USE OF THIS REVIEW 9 INTERNAL REVIEW 10 APPROVAL BY SPONSORS 10 (...) breathing, and shortness of breath. In advanced (metastatic) cancer, dyspnea has been reported in 53% of patients, with the highest rates (74%) in patients with lung cancer . Dyspnea is more frequent and severe in patients with pulmonary, pleural, or mediastinal involvement, and tends to increase over time. The first principle arising from the various guidelines is that the underlying cause of dyspnea needs to be identified and treated if possible . There are often comorbidities and it should
Dyspneacaused by a giant retroperitoneal liposarcoma: A case report Liposarcomas are the most common soft tissue tumors with various histological subtypes. They usually appear in the retroperitoneal region of the abdomen, but their symptomatology remains unclear and their diagnosis, as well as treatment challenging. A case of a 55-year-old female patient with dyspnea and light diffuse abdominal pain caused by a giant retroperitoneal liposarcoma is presented. The patient had an unremarkable (...) medical history, while the computed tomography scan revealed a large mass at the right portion of the abdomen, with its upper limits to the lower edge and the gate portion of the liver. The mass was in contact with the right kidney, the inferior vena cava and the right renal vein, causing mild dilation of the right kidney pelvis. Without any evidence of intra-abdominal metastases, the tumor was surgically resected. The histological analysis of the tumor revealed a well-differentiated liposarcoma
Giant liver tumor causingdyspnea upon exertion Asymptomatic elevation of the right hemidiaphragm should always raise suspicion of a silent hepatic tumor. Prompt multimodality imaging plays a critical role in the identification of this entity; high clinical suspicion is the key element for diagnosis of a possible hepatic tumor.
Causes of Dyspnea after Cardiac Surgery Postoperative dyspnea is common after cardiac surgery, even in low-risk patients. Cardiac surgeons and anesthesiologists are familiar with patients suffering from dyspnea in the early postoperative period, but in some cases, conventional treatment strategies may be ineffective, and a consultation with a pulmonologist may be required. The aim of this study is to investigate the causes of dyspnea after cardiac surgery in this particular patient group.The (...) hospital database was searched for non-emergency cardiac surgery for the period January 2014-October 2015. Individuals with an impaired spirometry result and a history of any pulmonic disease were excluded. Only patients for whom a pulmonary consultation was needed because of dyspnea in the postoperative course were enrolled in the study. Causes of dyspnea were analyzed according to consultation reports and computed tomography findings.One hundred and three patients were enrolled in the study. Of those
An uncommon cause of dyspnea in the emergency department. Chest pain and shortness of breath are chief complaints frequently evaluated in the emergency department. ACS, pulmonary embolism, and disorders involving the lung parenchyma are some of the disease processes commonly screened for. Occasionally, patients presenting with histories and clinical exams consistent with these common illnesses may end up having more rare pathology. We present the case of a young patient who presented with chest (...) pain and dyspnea with ECG changes and history concerning for pulmonary embolism who was ultimately diagnosed with idiopathic primary pulmonary hypertension. The importance of a prompt diagnosis of this condition along with emergency department management of complications related to the disease is discussed in this report.Published by Elsevier Inc.
A Rare Cause of Dyspnea: Undifferentiated Pleomorphic Sarcoma in the Left Atrium Primary cardiac tumors are a rare entity. The presence of a mass in the left atrium suggests myxoma as a first differential diagnosis. Here we present a rare case of a woman with exertional dyspnea with a large tumor in the left atrium. The patient was extensively studied with echocardiography, cardiac MRI, coronary angiography and computed tomography. Extracardiac neoplastic involvement was ruled out. The patient
Teratoma as unusual cause of chest pain, hemoptysis and dyspnea in a young patient A 16-year-old girl presented with intermittent left chest pain and breathlessness on exertion for last 4 months with one episode of haemoptysis. There has been loss of appetite and weight loss of 4 kg over a period of 1 month. A chest radiograph revealed a large mass like opacity with pleural effusion in the left lung field. Computerized Tomography scanning (CT scanning) and Positron Emission Tomography
Dyspnea Associated with Henna Stone: A Rare Cause of Pediatric Tracheotomy Tracheotomy is one of the oldest surgical procedures, and it is a life-saving procedure to overcome upper airway obstructions. While congenital causes play an important role in pediatric tracheotomy indications, upper airway edema and obstruction due to anaphylaxis rarely require tracheotomy. Allergy can cause life-threatening acute edema by anaphylactic reactions in the respiratory tract. Henna stone is the material
Relationship between Dyspnea Descriptors and Underlying Causes of the Symptom; a Cross-sectional Study History taking and physical examination help clinicians identify the patient's problem and effectively treat it. This study aimed to evaluate the descriptors of dyspnea in patients presenting to emergency department (ED) with asthma, congestive heart failure (CHF), and chronic obstructive pulmonary disease (COPD).This cross-sectional study was conducted on all patients presenting to ED (...) with chief complaint of dyspnea, during 2 years. The patients were asked to describe their dyspnea by choosing three items from the valid and reliable questionnaire or articulating their sensation. The relationship between dyspnea descriptors and underlying cause of symptom was evaluated using SPSS version 16.312 patients with the mean age of 60.96±17.01 years were evaluated (53.2% male). Most of the patients were > 65 years old (48.7%) and had basic level of education (76.9%). "My breath doesn't go out
Hypersensitivity pneumonitis: an overlooked cause of cough and dyspnea Hypersensitivity pneumonitis (HP) is an immune-mediated pulmonary disorder involving inflammation of the lung interstitium, terminal bronchioles, and alveoli caused by the immune response to the inhalation of an offending environmental airborne agent. It can manifest as exertional dyspnea, fatigue, weight loss, and progressive respiratory failure if left untreated. Because of its protean features, it can be misdiagnosed (...) as other common obstructive lung conditions such as asthma. If triggers are not avoided, it can progress to irreversible pulmonary fibrosis. In this article, we present the case of a 51-year-old male who presented to our hospital with recurrent bouts of dyspnea and cough, initially diagnosed as an asthma exacerbation. He received a final diagnosis of HP after investigation of his workplace revealed airborne spores and surface molds from multiple fungal species, serology revealed eosinophilia
A Rare Cause of Positional Dyspnea: Hypopharyngeal Hamartoma Hypopharyngeal hamartomas are quite rare tumors that may cause nutritional or respiratory problems in neonates and infants. They may be confused with other benign laryngeal lesions. In this study a 7-month-old infant with congenital stridor and positional dyspneacaused by a hypopharyngeal hamartoma was reported with review of the literature. Hypopharyngeal hamartomas should be considered in the differential diagnosis of pathologies (...) that cause respiratory or feeding problems in neonates or infants.
An unusual cause of severe dyspnea: A laryngeal live leech: Case report Foreign bodies in the upper airways are one of the most challenging otolaryngology emergencies, leeches present a very rare cause of airway foreign bodies around the world.A 6-year-old girl was referred to our otolaryngology department at a tertiary university hospital with a severe dyspnea and hemoptysis. Nasofibroscopy revealed a dark living leech in the supraglottic area which extends to the glottis. The patient
Giant Left Atrial Myxoma: Cause for Position-Dependent Nocturnal Dyspnea and Cardiac Murmur Primary tumors of the heart are rare. The majority of them are benign, the left atrial myxoma being the most frequent one. Clinical appearance varies from unapparent to life-threatening complications such as stroke, acute heart failure, or even sudden death. Diagnosis and consecutive surgical treatment strongly depend on the clinical symptoms, but their extent does not correlate with the risk for serious
Endobronchial lipoma causing progressive dyspnea We describe a 63-year-old male who presented with progressive exertional dyspnea, post-obstructive pneumonia and chest CT findings of an endobronchial lesion. Bronchoscopy revealed an endobronchial lipoma, which was resected using snare electrocautery. Complete resolution of the patient's symptoms was noted following bronchoscopic resection.
factors that may provoke various physiologic and behavioral responses. Clinical history and physical examination may provide insight into the cause or causes of dyspnea; however, laboratory and ancillary tests are also often necessary. Chronic dyspnea implies shortness of breath of >1 month duration . The differential diagnosis encompasses a wide variety of pathologies , including cardiovascular, pulmonary, gastrointestinal, neuromuscular, systemic, and psychogenic disorders. A multifactorial (...) -Suspected Cardiac Origin”  and the ACR Appropriateness Criteria ® topic on “Suspected Pulmonary Hypertension”  for further details. Overview of Imaging Modalities Radiography Chest The workup of chronic dyspnea is influenced by its severity, the rate of worsening, and the presence or absence of risk factors and other symptoms. The initial evaluation is aimed at determining whether the cause is related to cardiovascular disease, pulmonary disease, a combination of both, or neither. A chest
lung cancer, or terminal hematological malignancy, along with many non-malignant causes. Among patients with cancer, hemoptysis is most common in lung cancer, with approximately 20% of lung cancer patients experiencing hemoptysis during the course of their illness (8). Recognizing that patients with SVCO, dyspnea and hemoptysis may benefit from a multidisciplinary palliative/supportive care team (including physiotherapy therapy/ occupational therapy/ psychosocial support/ speech-language pathology (...) -YAG laser, and stenting may also be considered for symptom control related to airway obstruction, compression or invasion (12,28,32), with excellent relief of dyspnea demonstrated in retrospective studies of these interventions (33-36). These local modalities should be strongly considered prior to institution of RT if the risk of acute RT-induced edema causing complete obstruction is considered high, and/or in the setting of recurrent or progressive disease post-RT. Antineoplastic modalities