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Dyspepsia in Pregnancy

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104. CUA guideline on adult overactive bladder

, hepatic Dry mouth, headache, accommodation disorder, visual impairment, constipation, abdominal pain, dyspepsia, and fatigue Beta-3 adrenoceptor agonist Mirabegron Myrbetriq ® A 25 or 50 mg OD Renal, hepatic Nausea, headache, hypertension, UTI, nasopharyngitis Severe uncontrolled hypertension, pregnancy BID: twice a day; CNS AE: central nervous system adverse effects; ER: extended release; GI: gastrointestinal; GU: genitourinary; IR: immediate release; OD: once a day; QID: four times a day; TID: three (...) management of overactive bladder Category Drug Brand name Grade Recommended doses Considerations in medically complex elderly Dose adjustment Adverse events Contraindications Antimuscarinics Oxybutynin Ditropan Ditropan XL A IR: 5 mg BID, TID, or QID ER: 5 or 10 mg OD Data show efficacy of 2.5mg bid. 235,272 Doses of 20 mg daily consistently associated with cognitive impairment, unreported by patients 252 Elderly Dry mouth, constipation, CNS AE Pregnancy or breast- feeding; drug hypersensitivity

2017 CPG Infobase

106. Gastroesophageal Reflux Disease (GERD) - Guidelines for Prescribing H2RAs and PPIs

affect children and infants as well as adults Classic symptoms are heartburn and regurgitation Caused by a number of mechanisms, the most important being a transient relaxation of the lower esophageal sphincter. Increased lower abdominal pressure, reduced lower esophageal sphincter tone, delayed gastric emptying, and impaired esophageal clearance may also be involved Risk factors: Being overweight or obese Diet Pregnancy Smoking Other conditions: crohn’s disease, celiac disease, hypothyroidism (...) , shoulder, or down the arm. Often associated with breathlessness/sweating Peptic ulcer disease, malignancy - see alarm symptoms below in "When to Refer" Medication-induced reflux - see list above of medications which increase the risk of GERD Medication-induced esophagitis - use of bisphosphonates, clindamycin, ethanol, iron, NSAIDs (including ASA and celecoxib), quinidine, potassium chloride, tetracyclines Functional dyspepsia - symptoms such as abdominal pain and fullness in addition to heartburn

2018 medSask

107. Dysmenorrhea

occurs with ovulatory cycles. Primary dysmenorrhea is most common in young women and less so in women beyond their late 20's. This decrease in incidence and severity may be related to pregnancy because, during late pregnancy, uterine adrenergic nerves virtually disappear and only a portion regenerate after childbirth. Secondary dysmenorrhea is painful menstruation caused by another condition, such as endometriosis, pelvic inflammatory disease, fibroids, or incorrect IUD insertion. Dysmenorrhea (...) bleeding, vaginal discharge, postcoital bleeding) Common causes: endometriosis, fibroids, pelvic inflammatory disease Insertion of intrauterine device within last 6 months Rectal pain or bleeding may indicate recto-vaginal endometriosis. Rule out pregnancy Miscarriage and ectopic pregnancy can present with new onset of pain and bleeding Other Conditions which can Cause Similar Pain Abnormal uterine structure Unilateral or non-midline pain occurring around time of menses. This is usually benign

2018 medSask

109. The Australasian Society for Infectious Diseases and Refugee Health Network of Australia recommendations for health assessment for people from refugee-like backgrounds: an abridged outline Full Text available with Trip Pro

high prevalence countries or have had prior household contact); HIV serology (age ≥ 15 years, unaccompanied minors); hepatitis B surface antigen (HBsAg) testing (pregnant women, unaccompanied minors, onshore protection visas, health care workers); hepatitis C virus (HCV) antibody testing (onshore protection visas, health care workers); and syphilis serology (age ≥ 15 years, humanitarian visas, onshore protection visas). Humanitarian entrants are also offered a voluntary pre-departure health check (...) out details of country-specific recommendations. A brief overview is provided below. For more detailed recommendations regarding management, follow-up and considerations for children and in pregnancy, see the full guidelines. Infectious conditions TB: Offer latent TB infection testing with the intention to offer preventive treatment and follow-up. Offer screening for latent TB infection to all people aged ≤ 35 years. Children aged 2–10 years may have been screened for latent TB infection as part

2017 MJA Clinical Guidelines

110. Paediatric Urology

of erythropoietin during testicular torsion of the rats. World J Urol, 2007. 25: 531. 185. Lian, B.S., et al. Factors Predicting Testicular Atrophy after Testicular Salvage following Torsion. Eur J Pediatr Surg, 2016. 26: 17. 186. Philip, J., et al. Mumps orchitis in the non-immune postpubertal male: a resurgent threat to male fertility? BJU Int, 2006. 97: 138. 187. Gielchinsky, I., et al. Pregnancy Rates after Testicular Torsion. J Urol, 2016. 196: 852. 188. Bergman, J.E., et al. Epidemiology of hypospadias

2018 European Association of Urology

111. Chronic Pelvic Pain

of the story. Hum Reprod Update, 2009. 15: 177. 330. Vercellini, P., et al. Medical treatment for rectovaginal endometriosis: what is the evidence? Hum Reprod, 2009. 24: 2504. 331. Walters, C., et al. Pelvic girdle pain in pregnancy. Aust J Gen Pract, 2018. 47: 439. 332a. Khan, K.S., et al. MRI versus laparoscopy to diagnose the main causes of chronic pelvic pain in women: a test-accuracy study and economic evaluation. Health Technol Assess, 2018. 22: 1. 332b. Kaminski, P., et al. The usefulness

2018 European Association of Urology

112. Nonsurgical Treatments for Urinary Incontinence in Women: A Systematic Review Update

with PROSPERO, and its registration number is CRD42017069903. We included all eligible studies included in the 2012 review. For newer studies, we searched multiple medical literature databases and sources of unpublished (grey) literature for articles from January 1, 2011 through our final search date of December 4, 2017. Table A presents the basic study eligibility criteria; the full report has further details. Table A. Summary of the eligibility criteria PICOTS Inclusion Exclusion Population Non-pregnant (...) community-dwelling adult women with symptoms of UI Subpopulations: • women engaging in athletic activity, • older women • women in the military or veterans • racial and ethnic minorities If >10% of study participants are from ineligible groups (children or adolescents, men, pregnant women, institutionalized or hospitalized participants, or have surgically-treated UI) Interventions Nonpharmacological interventions: Behavioral interventions, neuromodulation, intravesical pressure release devices

2018 Effective Health Care Program (AHRQ)

113. Antiocoagulation - oral

Antiocoagulation - oral Prodigy Toggle navigation Topics Specialities A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Allergies Cancer Cardiovascular Child health Drugs and devices Ear, nose and throat Endocrine and metabolic Eyes Gastroenterology Gastrointestinal Haematology Immunizations Infections and infestations Injuries Kidney disease and urology Men's health Mental health Musculoskeletal Neurological Oral health Palliative care Poisoning Pregnancy Preventative medicine Respiratory (...) and clinically relevant bleeding risk. A prosthetic heart valve. Apixaban is also contraindicated in: People who are taking any other anticoagulants, except when switching to or from warfarin treatment. People who are taking strong inhibitors of cytochrome P3A4 enzyme and P-glycoprotein, such as ketoconazole, or HIV protease inhibitors such as ritonavir. For more information, see . Women who are pregnant or breastfeeding. The safety of apixaban has not been established in pregnant or breastfeeding women

2017 Prodigy

118. Blood and Clots Series: Which antithrombotic therapy should I start for my patient with acute VTE? Full Text available with Trip Pro

factors help determine whether your patient is a good candidate for a DOAC 2 : Is there a contraindication to a DOAC? Individuals who are breastfeeding or pregnant should not be using DOACs as there is insufficient safety data and they were excluded from clinical trials. Patients with mechanical heart valves should be on Warfarin, not a DOAC 3 . Are there any significant drug-drug interactions? Drugs that induce/inhibit p-glycoprotei n may interact with Dabigatran, and drugs that induce/inhibit both p (...) , it is important that all doses are taken. Many patients prefer once-daily dosing (Rivaroxaban) over BID drugs (Dabigatran, Apixaban). Patients with potential cognitive impairment – Dabigatran cannot be blister-packed so other drugs should be considered in patients who require this aid to ensure appropriate medication utilization. History of GI bleeding, peptic ulcer disease, or dyspepsia – Consider anticoagulants besides Dabigatran or Rivaroxaban in these patients. Dabigatran has been associated

2018 CandiEM

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