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Dry Skin

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141. A prospective randomised comparison of 2 skin closure techniques in primary total hip arthroplasty surgery. (Abstract)

A prospective randomised comparison of 2 skin closure techniques in primary total hip arthroplasty surgery. As an essential step of total hip arthroplasty (THA), an effective and secure skin closure technique after primary THA is important. Metallic staples closure and subcuticular suture are the 2 common techniques for skin closure. However, which closure technique is the optimal skin-closure method remains unclear. The purpose of this prospective randomised clinical study was to compare (...) the clinical outcomes and costs between staples and subcuticular suture techniques.In this clinical study, 165 patients who underwent primary unilateral THA through a posterolateral approach from August 2014 to May 2015 were included. According to skin closure technique, the patients were randomised into staples group (interrupted suture with staples, 83 cases) and sutures group (running 4-0 absorbable subcuticular suture, 82 cases). The same operative and perioperative care were provided to all patients

2018 Hip international : the journal of clinical and experimental research on hip pathology and therapy Controlled trial quality: uncertain

142. Effect of Passion Fruit Seed Extract Rich in Piceatannol on the Skin of Women: A Randomized, Placebo-Controlled, Double-Blind Trial. Full Text available with Trip Pro

passion fruit seed extract on the skin of healthy Japanese women (age, 35-54 y). Thirty-two women with dry skin received either passion fruit seed extract (5 mg piceatannol) or a placebo (dextrin) for 8 wk. Skin hydration and other parameters on the face were assessed at 0, 4, and 8 wk by using specialized equipment. Furthermore, questionnaire interviews were conducted regarding the physical condition of subjects at 0, 4, and 8 wk. The results showed that consumption of passion fruit seed extract led (...) " and "fatigue" in the passion fruit seed extract group as compared with the placebo group. These results indicate that oral intake of passion fruit seed extract that is rich in piceatannol could improve the moisture of dry skin and reduce fatigue.

2018 Journal of nutritional science and vitaminology Controlled trial quality: uncertain

143. Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatchâ„¢). Full Text available with Trip Pro

Safety, tolerability, acceptability and immunogenicity of an influenza vaccine delivered to human skin by a novel high-density microprojection array patch (Nanopatchâ„¢). Injection using needle and syringe (N&S) is the most widely used method for vaccination, but requires trained healthcare workers. Fear of needles, risk of needle-stick injury, and the need to reconstitute lyophilised vaccines, are also drawbacks. The Nanopatch (NP) is a microarray skin patch comprised of a high-density array (...) of microprojections dry-coated with vaccine that is being developed to address these shortcomings. Here we report a randomised, partly-blinded, placebo-controlled trial that represents the first use in humans of the NP to deliver a vaccine.Healthy volunteers were vaccinated once with one of the following: (1) NPs coated with split inactivated influenza virus (A/California/07/2009 [H1N1], 15 µg haemagglutinin (HA) per dose), applied to the volar forearm (NP-HA/FA), n = 15; (2) NPs coated with split inactivated

2018 Vaccine Controlled trial quality: predicted high

144. Comparison of skin hydration in combination and single use of common moisturizers (cream, toner, and spray water). (Abstract)

). The hydration rate of C-S differed slightly from T-T, followed by those four mentioned above, with T being the last. For dry skin (hydration value at baseline <35 a.u.), no statistical significance could be detected between C-T zone and C+T, T+C, and C zones ( p > 0.05), the other results were identical. When cream and toner were applied successively, the application order has little effect on skin hydration. The application of cream only was an effective and brief way to achieve favorable moisturization (...) especially for dry skin. As a complement, repeated application of toner rather than spray water is efficacious for skin hydration.

2018 Journal of cosmetic science Controlled trial quality: uncertain

145. Short- and long-term effects of two emollients on itching and skin restoration in xerotic eczema. Full Text available with Trip Pro

Short- and long-term effects of two emollients on itching and skin restoration in xerotic eczema. Pruritus is associated with various skin diseases, dry skin, and with it an impaired skin barrier function. The study objective was to investigate short-term and long-term effects of two emollients on symptoms and skin barrier functions in xerotic eczema. Randomized, double-blind, study enrolling females/males, with bilateral itching. Two emollients, containing lactic acid and refined almond oil (...) with/without polidocanol were administered on left versus right body sides. Itching severity, skin moisture, lipid content, and pH were assessed on Day 1, within 30-120 min after first administration, and on Days 7 and 14, and compared with baseline assessments. Severity of itching decreased 30 min after first administration of both emollients compared with baseline (p < .0001) and reached a maximum reduction of 63% (p < .0001) and 69% (p < .0001) on Day 14. Skin moisture and lipid content increased after

2018 Dermatologic therapy Controlled trial quality: uncertain

146. Optimization of Antioxidant and Skin-Whitening Compounds Extraction Condition from Tenebrio molitor Larvae (Mealworm) Full Text available with Trip Pro

Optimization of Antioxidant and Skin-Whitening Compounds Extraction Condition from Tenebrio molitor Larvae (Mealworm) Skin-whitening ingredients are a very important part of the development of functional cosmetics and a wide variety of raw materials are used. Tyrosinase is a key enzyme in the animal melanogenic pathway that is the rate-limiting step for the production of melanin. Several synthetic and naturally occurring tyrosinase inhibitors have been studied for skin-whitening (...) , and ethanol concentration were optimized using response surface methodology (RSM). The results showed that optimum extraction temperature of 88.1 °C, extraction time of 43.7 min, and ethanol concentration of 72.0 v/v%, provided the predicted maximum levels of total phenolic compounds (TPC) of 5.41 mg GAE/g dry weight (DW) and tyrosinase inhibition activity (TIA) of 82.4%. From the validation experiment, 5.61 ± 0.2 mg GAE/g dry weight (DW), tyrosinase inhibition of 79.6 ± 3.3%, and radical scavenging

2018 Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

147. Spatial and temporal migration of sweat: from skin to clothing Full Text available with Trip Pro

Spatial and temporal migration of sweat: from skin to clothing Moisture accumulation in clothing affects human performance and productivity through its impact on thermal balance and various aspects of discomfort. Building on our laboratory's work on mapping sweat production across the body, this study aimed to obtain detailed spatial and temporal maps showing how this sweat migrates into a single clothing layer (T-shirt) during physical exercise.Eight male participants performed running (...) exercise in a warm environment. Garment sweat absorption was mapped over a total running time of 50 min, in 10 separated running trials of different durations (5 min increments). After running, the garment was dissected into 22 different parts and local sweat absorption (ABSlocal) was quantified by weighing each garment part before and after drying. From ABSlocal, garment total sweat absorption (ABStotal) was estimated.After 50 min, Tcore rose from 37 ± 0.2 to 38.6 ± 0.3 °C, HR increased from 69 ± 15

2018 European journal of applied physiology

148. Assessing the accumulated stickiness magnitude from fabric–skin friction: effect of wetness level of various fabrics Full Text available with Trip Pro

fabric offered throughout the drying period, was developed. Thin cotton fabrics (fabric W01 and W03), having higher saturation level after contacting with wetted skin surface, arouse stronger stickiness feeling and their ASM is remarkably higher. The difference in stickiness estimates is due to the difference in chemical composition and surface geometry. This study suggests us the way to predict perceived stickiness in fabrics with different wetness levels which is useful for applications like (...) Assessing the accumulated stickiness magnitude from fabric–skin friction: effect of wetness level of various fabrics Increasing skin wetness tends to increase fabric-skin adhesion and friction, resulting in wear discomfort or skin injuries. Here, the magnitude estimation approach was used to assess the stickiness sensation perceived in fabrics. Seven fabric types were wetted by putting onto wet 'skin' surface and dried for different durations to achieve different wetness levels, simulating

2018 Royal Society Open Science

149. Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems Full Text available with Trip Pro

Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems Moisturizers are topical products designed to improve and maintain the skin barrier function and to help prevent dry skin.A new moisturizer (Ceramide cream) was formulated containing ingredients which mimic the skin's own natural moisturizing systems. Corneometry was performed at baseline, 2, 4, 6 and 24 hours following a single application of Ceramide cream to healthy skin (...) function which may make it suitable for use on dry skin.

2018 Clinical, cosmetic and investigational dermatology Controlled trial quality: uncertain

150. Highly Adaptable and Biocompatible Octopus‐Like Adhesive Patches with Meniscus‐Controlled Unfoldable 3D Microtips for Underwater Surface and Hairy Skin Full Text available with Trip Pro

Highly Adaptable and Biocompatible Octopus‐Like Adhesive Patches with Meniscus‐Controlled Unfoldable 3D Microtips for Underwater Surface and Hairy Skin Adhesion capabilities of various skin architectures found in nature can generate remarkable physical interactions with their engaged surfaces. Among them, octopus suckers have unique hierarchical structures for reversible adhesion in dry and wet conditions. Here, highly adaptable, biocompatible, and repeatable adhesive patches (...) on a Si wafer in both dry and underwater conditions (max. 11 N cm-2 in pull-off strength) as well as on a moist pigskin (max. 14.6 mJ peeling energy). Moreover, the geometry-controlled microsuckers exhibit high-repeatability (over 100 cycles) in a pull-off direction. The adhesive demonstrates stable attachments on a moist, hairy, and rough skin, without any observable chemical residues.

2018 Advanced Science

151. Prediction of Steam Burns Severity using Raman Spectroscopy on ex vivo Porcine Skin Full Text available with Trip Pro

Prediction of Steam Burns Severity using Raman Spectroscopy on ex vivo Porcine Skin Skin burns due to accidental exposure to hot steam have often been reported to be more severe than the ones occurring from dry heat. While skin burns due to flames or radiant heat have been thoroughly characterized, the mechanisms leading to steam burns are not well understood and a conundrum still exists: can second degree burns occur without destruction of the epidermis, i.e. even before first degree burns (...) are detected? Skin permeability is dependent both on temperature and on the kinetic energy of incoming water molecules. To investigate the mechanism underlying the injuries related to steam exposure, we used porcine skin as an ex vivo model. This model was exposed to either steam or dry heat before measuring the skin hydration via confocal Raman microspectroscopy. The results show that during the first minute of exposure to steam, the water content in both the epidermis and dermis increases. By analyzing

2018 Scientific reports

152. Skin Disorders and Primary Tumor Location as Prognostic Factors in Patients with Metastatic Colorectal Cancer Treated with Cetuximab and Chemotherapy Full Text available with Trip Pro

patient. The OS and PFS in relation to the location of the primary tumors and presence or absence of skin disorder were also compared. Results: Total frequency of each skin disorder as rash acneiform, paronychia, and dry skin in patients with left- and right-sided mCRC was 70%, 70%, and 43% and 27%, 36%, and 27%, respectively. The median OS was 8.9 months for mCRC on the left-sided without skin disorder and 56.3 months for mCRC on the left-sided with skin disorder. In comparison, the median OS (...) Skin Disorders and Primary Tumor Location as Prognostic Factors in Patients with Metastatic Colorectal Cancer Treated with Cetuximab and Chemotherapy Background: Cetuximab-induced skin disorder is common in colorectal cancer (CRC), and is known to affect prolonged overall survival (OS). Patients with left-sided CRC survive longer than those with right-sided CRC, among those treated with combination cetuximab and chemotherapy. However, no study has evaluated patient prognosis in terms of OS

2018 Asian Pacific journal of cancer prevention : APJCP

153. Association of psychological stress with skin symptoms among medical students Full Text available with Trip Pro

students suffered from more oily, waxy patches or flakes on scalp (p≤0.0001), dry/sore rash (p≤0.0001), warts (p≤0.0001), pimples (p≤0.0001), itchy skin (p≤0.0001), hands itchy rash (p≤0.0001), hair loss (p≤0.0001), pull-out own hair (p=0.008), scaly skin (p=0.012), troublesome sweating (p=0.016), nails biting (p=0.028), and other rashes on face (p= 0.028).  Conclusion: Various common skin conditions could appear in context of psychological stress among medical students. (...) Association of psychological stress with skin symptoms among medical students To evaluate the association between psychological stress and skin symptoms among medical students.  Methods: A cross-sectional study was carried out between January and June 2015. Electronic survey consists of Perceived Stress Questionnaire (PSQ) and Self-Reported Skin Complaints Questionnaire were distributed to all 1435 undergraduate students at College of Medicine, King Saud University (KSU), Riyadh, Saudi Arabia

2018 Saudi medical journal

154. Improvement of skin conditions by ingestion of Aspergillus kawachii (Koji) extract containing 14-dehydroergosterol in a randomized, double-blind, controlled trial Full Text available with Trip Pro

was dry ingested either a placebo dietary supplement or Koji extract (200 mg/day) supplement containing 0.1% 14-DHE for 12 weeks. Throughout the treatment period and for 4 weeks afterward, objective indicators - including moisture content of the stratum corneum, trans-epidermal water loss (TEWL), and skin wrinkles - were evaluated; in addition, the subjects answered a questionnaire on their skin conditions with ratings on a visual analog scale. Statistical analysis was conducted on the basis (...) Improvement of skin conditions by ingestion of Aspergillus kawachii (Koji) extract containing 14-dehydroergosterol in a randomized, double-blind, controlled trial The present study examined the effect of ingestion of Koji extract containing 14-dehydroergosterol (14-DHE), prepared from Aspergillus kawachii NBRC4308, on improvement of skin conditions among healthy volunteers.In a randomized, double-blind, placebo-controlled, parallel-group study, 70 healthy adult women who felt that their skin

2018 Clinical, cosmetic and investigational dermatology Controlled trial quality: uncertain

155. Tactile Sliding Behavior of R2R Mass-Produced PLLA Nanosheet towards Biomedical Device in Skin Applications Full Text available with Trip Pro

Tactile Sliding Behavior of R2R Mass-Produced PLLA Nanosheet towards Biomedical Device in Skin Applications In this research, sliding friction was measured between the fingertip and nanosheet on a silicon substrate under two conditions: dry and wet. By using a force transducer, the tactile friction force and applied load were measured. According to the experimental results, the relationship of friction force and applied load exhibits a positive correlation under both dry and wet conditions (...) . In addition, the nanosheets are able to reduce the friction force and coefficient of friction (COF) compared to the reference sample, especially under the wet condition. Under the assumption of a full contact condition, the estimated contact area increases with larger applied loads. Furthermore, based on the wear observation, the skin sliding performance caused slight abrasions to the surface of the nanosheet samples with a mild wear track along the sliding direction. Overall, the sliding behavior between

2018 Nanomaterials

156. Non-Invasive Electromagnetic Skin Patch Sensor to Measure Intracranial Fluid–Volume Shifts Full Text available with Trip Pro

Non-Invasive Electromagnetic Skin Patch Sensor to Measure Intracranial Fluid–Volume Shifts Elevated intracranial fluid volume can drive intracranial pressure increases, which can potentially result in numerous neurological complications or death. This study's focus was to develop a passive skin patch sensor for the head that would non-invasively measure cranial fluid volume shifts. The sensor consists of a single baseline component configured into a rectangular planar spiral with a self (...) -resonant frequency response when impinged upon by external radio frequency sweeps. Fluid volume changes (10 mL increments) were detected through cranial bone using the sensor on a dry human skull model. Preliminary human tests utilized two sensors to determine feasibility of detecting fluid volume shifts in the complex environment of the human body. The correlation between fluid volume changes and shifts in the first resonance frequency using the dry human skull was classified as a second order

2018 Sensors (Basel, Switzerland)

157. Chitosan-carboxymethyl-5-fluorouracil-folate conjugate particles: Microwave modulated uptake by skin and melanoma cells. Full Text available with Trip Pro

-drying technique. The size, zeta potential, morphology, drug content, and drug release, as well as skin permeation and retention, pharmacokinetics, in vitro SKMEL-28 melanoma cell line cytotoxicity, and intracellular trafficking profiles of drug/particles, were examined as a function of skin/melanoma cell treatment by microwaves at 2,450 MHz for 5 + 5 minutes. The level of skin drug/particle retention in vitro and in vivo increased in skin treated by microwaves. This was facilitated by the drug (...) Chitosan-carboxymethyl-5-fluorouracil-folate conjugate particles: Microwave modulated uptake by skin and melanoma cells. 5-Fluorouracil delivery profiles in the form of chitosan-folate submicron particles through skin and melanoma cells in vitro were examined using microwaves as the penetration enhancer. The in vivo pharmacokinetic profile of 5-fluorouracil was also determined. Chitosan-carboxymethyl-5-fluorouracil-folate conjugate was synthesized and processed into submicron particles by spray

2018 Journal of Investigative Dermatology

158. A Study to Determine the Safety and Sensitizing Potential of HAT1 Topical Products Using Skin Sensitivity Patch Tests

to keep their patches dry. Subjects were instructed to return to the test facility for patch removal and disposal by test facility personnel. Skin sites were gently wiped with water and patted dry to remove excess test substance immediately following patch removal. Skin sites were graded approximately 20-40 minutes following patch removal. Subjects were not allowed to replace any patches that fall off. Subjects were provided with instructions and a schedule of the study dates on the first day (...) A Study to Determine the Safety and Sensitizing Potential of HAT1 Topical Products Using Skin Sensitivity Patch Tests A Study to Determine the Safety and Sensitizing Potential of HAT1 Topical Products Using Skin Sensitivity Patch Tests - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2018 Clinical Trials

159. A Community-based Assessment of Skin Care, Allergies, and Eczema

. These emollients include (1) CeraVe Healing Ointment, (2) Vaseline, (3) Cetaphil cream, (4) CeraVe cream, and (5) Vanicream. Other: Participant choice of over-the-counter emollients: Vaseline, Vanicream, CeraVe Healing Ointment, CeraVe cream, Cetaphil cream Lipid-rich emollient serving as skin barrier No Intervention: Natural Skin Parents assigned to the control arm will receive educational materials promoting general infant skin care guidelines only and will be asked to refrain from emollient use unless dry (...) A Community-based Assessment of Skin Care, Allergies, and Eczema A Community-based Assessment of Skin Care, Allergies, and Eczema - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Community-based Assessment

2018 Clinical Trials

160. Clinical Trial to Assess the Effects of Topical Lotions on Changes in the Skin Microbiome and Associations With Itch

) drug monographed ingredient for treatment of eczema. The other group was supplied with a cosmetic test product which is a standard dry skin daily moisturizer. Both groups were also provided with a cosmetic test cleanser to use in place of their normal cleanser. Subjects used the products for 14 days, followed by a 7-day regression period (no product use). Subjects were assessed at Baseline and at Day 1, Day 3, Day 7, and Day 14 of product use. They were assessed again 7 days after stopping product (...) an OTC drug monographed ingredient for treatment of eczema and the other group was supplied with a cosmetic test product which is a standard dry skin daily moisturizer. Both groups were also provided with a cosmetic test cleanser to use in place of their normal cleanser. There was a 7-day regression period following the 14 days of product use. Masking: Triple (Participant, Investigator, Outcomes Assessor) Primary Purpose: Basic Science Official Title: A Multi-Center, Controlled Clinical Trial

2018 Clinical Trials

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