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81. Evaluation of absorbent materials for use as ad hoc dry decontaminants during mass casualty incidents as part of the UK's Initial Operational Response (IOR). Full Text available with Trip Pro

cleansing of the skin with dry absorbent materials has previously been identified as a potential means of facilitating emergency decontamination. The purpose of this study was to evaluate the in vitro oil and water absorbency of a range of materials commonly found in the domestic and clinical environments and to determine the effectiveness of a small, but representative selection of such materials in skin decontamination, using an established ex vivo model. Five contaminants were used in the study (...) : methyl salicylate, parathion, diethyl malonate, phorate and potassium cyanide. In vitro measurements of water and oil absorbency did not correlate with ex vivo measurements of skin decontamination. When measured ex vivo, dry decontamination was consistently more effective than a standard wet decontamination method ("rinse-wipe-rinse") for removing liquid contaminants. However, dry decontamination was ineffective against particulate contamination. Collectively, these data confirm that absorbent

2017 PLoS ONE

82. Volunteer trials of a novel improvised dry decontamination protocol for use during mass casualty incidents as part of the UK'S Initial Operational Response (IOR). Full Text available with Trip Pro

Volunteer trials of a novel improvised dry decontamination protocol for use during mass casualty incidents as part of the UK'S Initial Operational Response (IOR). Previous studies have demonstrated that rapid evacuation, disrobing and emergency decontamination can enhance the ability of emergency services and acute hospitals to effectively manage chemically-contaminated casualties. The purpose of this human volunteer study was to further optimise such an "Initial Operational Response" by (1 (...) ) identifying an appropriate method for performing improvised skin decontamination and (2) providing guidance for use by first responders and casualties. The study was performed using two readily available, absorbent materials (paper towels and incontinence pads). The decontamination effectiveness of the test materials was measured by quantifying the amount of a chemical warfare agent simulant (methyl salicylate) removed from each volunteer's forearm skin. Results from the first study demonstrated

2017 PLoS ONE

83. The adverse skin reactions of health care workers using personal protective equipment for COVID-19. Full Text available with Trip Pro

total of 61 valid questionnaires were collected. The most common adverse skin reactions among HCWs wearing N95 masks were nasal bridge scarring (68.9%) and facial itching (27.9%). The most common adverse skin reactions among HCWs wearing latex gloves were dry skin (55.7%), itching (31.2%), and rash (23.0%). The most common adverse skin reactions among HCWs wearing protective clothing were dry skin (36.1%) and itching (34.4%).When most HCWs wear PPE for a long period of time, they will experience (...) The adverse skin reactions of health care workers using personal protective equipment for COVID-19. In December 2019, a new coronavirus was found in Wuhan, Hubei Province, China, and spread rapidly throughout the country, attracting global attention. On February 11, the World Health Organization (WHO) officially named the disease caused by 2019-nCoV coronavirus disease 2019 (COVID-19). With the increasing number of cases, health care workers (HCWs) from all over China volunteered to work

2020 Medicine

84. Aqueous olanexidine versus aqueous povidone-iodine for surgical skin antisepsis on the incidence of surgical site infections after clean-contaminated surgery: a multicentre, prospective, blinded-endpoint, randomised controlled trial. (Abstract)

Aqueous olanexidine versus aqueous povidone-iodine for surgical skin antisepsis on the incidence of surgical site infections after clean-contaminated surgery: a multicentre, prospective, blinded-endpoint, randomised controlled trial. Surgical site infection (SSI) is the most common problem after surgery. Although several guidelines have indicated the efficacy of antiseptics, such as chlorhexidine-alcohol and povidone-iodine, in reducing SSI rate, the optimal recommendation is still (...) not established. Olanexidine might have higher bactericidal activity than other antiseptic agents. However, no randomised study has evaluated the efficacy and safety of olanexidine over conventional antiseptics. We compared the effect of aqueous olanexidine and aqueous povidone-iodine on the incidence of SSI following clean-contaminated surgery.This was a multicentre, prospective, randomised, blinded-endpoint superiority trial for surgical skin antisepsis in clean-contaminated gastrointestinal

2020 Lancet infectious diseases

85. Skin barrier function after repeated short-term application of alcohol-based hand rub following intervention with water immersion or occlusion. (Abstract)

Skin barrier function after repeated short-term application of alcohol-based hand rub following intervention with water immersion or occlusion. Alcohol-based hand rub (ABHR) is recommended for hand hygiene, and application on dry skin is generally well tolerated. However, hydration of the skin may lead to increased susceptibility to ABHR.To evaluate if increased skin hydration changes skin barrier response to ABHR, as compared to application on dry skin.Twenty healthy volunteers participated (...) in a 3-day experimental setup. Intervention areas on the forearms were exposed to either water immersion or occlusion followed by repeated exposures to ABHR. Skin barrier function was assessed by measurement of transepidermal water loss (TEWL), electrical conductance, pH, and erythema at baseline and day 3.The area exposed to water immersion preceding ABHR showed a significant increase in TEWL from baseline to day 3 (P = .04), and for the occluded area the same trend was found (P = .11

2020 Contact Dermatitis

86. Topographical diversity of common skin microflora and its association with skin environment type: An observational study in Chinese women Full Text available with Trip Pro

), association with biomarkers (antimicrobial peptides: LL-37, β-defensins [HBD-2, HBD-3]), and claudin-1) and skin biophysical parameters (transepidermal water loss, pH, skin scaliness and roughness, sebum and hydration levels) were also determined. Skin sites (glabella [GL], hand-back [HB], interdigital web-space [IS], antecubital fossa [AF], volar forearm [VF], back [BA]) were classified as normal, oily or dry based on two-step cluster analysis and exposed or unexposed (uncovered or covered by clothes (...) , respectively) based on seasonal apparel. Pseudomonadaceae and Staphylococcus aureus had the highest and lowest detection rate respectively at all sites. Cluster analysis identified skin sites as 'normal' (HB, BA, AF, VF), 'dry' (IS) and 'oily' (GL). Bacterial alpha diversity was higher in exposed (HB, IS, and GL) compared with unexposed sites (BA, AF and VF). Co-occurrence of Staphylococcus aureus with any of the other five microorganisms was lower in dry and oily skin versus normal skin. Skin exposure

2017 Scientific reports

87. Associations between skin barrier characteristics, skin conditions and health of aged nursing home residents: a multi-center prevalence and correlational study. Full Text available with Trip Pro

parameters were not associated with overall care dependency, but with age and skin dryness. In general, skin dryness and measured skin barrier parameters were associated between arms and legs indicating similar overall skin characteristics of the residents.Prevalence of xerosis cutis, pressure ulcers and skin tears were high, indicating the load of these adverse skin conditions in this population. Only few associations of demographic characteristics, skin barrier impairments and the occurrence of dry (...) Associations between skin barrier characteristics, skin conditions and health of aged nursing home residents: a multi-center prevalence and correlational study. Geriatric patients are affected by a range of skin conditions and dermatological diseases, functional limitations and chronic diseases. Skin problems are highly prevalent in elderly populations. Aim of this study was to investigate possible associations between health, functional and cutaneous variables in aged long-term care

2017 BMC Geriatrics

88. The effectiveness of standardized skin care regimens on skin dryness in nursing home residents: A randomized controlled parallel-group pragmatic trial. (Abstract)

The effectiveness of standardized skin care regimens on skin dryness in nursing home residents: A randomized controlled parallel-group pragmatic trial. Aged residents of institutional long-term care facilities are at high risk for developing skin and tissue diseases. Besides various common skin problems, dry skin (xerosis cutis) is one of the most frequent skin conditions in this setting.To investigate the effectiveness of two structured skin care regimens in comparison to routine skin care (...) on xerosis cutis in nursing home residents.A multi-center, pragmatic, randomized, controlled, investigator blinded study with three parallel groups.The study was conducted in a random sample of ten out of 291 institutional long-term care facilities of the federal state of Berlin, Germany.Long-term care residents being 65+ years affected by dry skin were included.The residents were allocated into one of three study groups. Two interventional groups used standardized skin care regimens, consisting

2017 International journal of nursing studies Controlled trial quality: uncertain

89. Genetics of Skin Cancer (PDQ®): Health Professional Version

Genetics of Skin Cancer (PDQ®): Health Professional Version Genetics of Skin Cancer (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf Warning: The NCBI web site requires JavaScript to function. Search database Search term Search NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): ; 2002 (...) -. Search term Genetics of Skin Cancer (PDQ®) Health Professional Version PDQ Cancer Genetics Editorial Board . Published online: January 3, 2020. Created: July 29, 2009 . This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the genetics of skin cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care

2018 PDQ - NCI's Comprehensive Cancer Database

90. Neurophysiological Effects of Dry Needling in Patients With Neck Pain

clinical criteria are found. Exclusion Criteria: Unsurpassed fear of needles. Coagulation disorders. Specific alterations of the cervical region in the clinical history. Infiltration of corticosteroids or local anesthetics during a year before the study. Surgical intervention of the cervical region or previous shoulder. Skin lesions in the area, as well as infection or inflammation. Taking analgesic, anti-inflammatory or anticoagulant medication the week before the study. Treatment of MTP or Deep Dry (...) Neurophysiological Effects of Dry Needling in Patients With Neck Pain Neurophysiological Effects of Dry Needling in Patients With Neck Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Neurophysiological

2017 Clinical Trials

91. Dry Needling for Patients With Neck Pain: Protocol of a Randomized Clinical Trial Full Text available with Trip Pro

Dry Needling for Patients With Neck Pain: Protocol of a Randomized Clinical Trial Neck pain is a costly and common problem. Current treatments are not adequately effective for a large proportion of patients who continue to experience recurrent pain. Therefore, new treatment strategies should be investigated in an attempt to reduce the disability and high costs associated with neck pain. Dry needling is a technique in which a fine needle is used to penetrate the skin, subcutaneous tissues (...) , and muscle with the intent to mechanically disrupt tissue without the use of an anesthetic. Dry needling is emerging as a treatment modality that is widely used clinically to address a variety of musculoskeletal conditions. Recent studies of dry needling in mechanical neck pain suggest potential benefits, but do not utilize methods typical to clinical practice and lack long-term follow-up. Therefore, a clinical trial with realistic treatment time frames and methods consistent with clinical practice

2017 JMIR Research Protocols Controlled trial quality: predicted high

92. Dry Needling and Low-level Laser Therapy to Treat Myofascial Pain

Dry Needling and Low-level Laser Therapy to Treat Myofascial Pain Dry Needling and Low-level Laser Therapy to Treat Myofascial Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Dry Needling and Low-level (...) the trigger points. Dry Needling and Low-Level Laser Therapy (LLLT) has been described as good resources to treat myofascial pain. The hypothesis is that the association of the purposed interventions will have greater effects than only the dry needling intervention. The objective is to evaluate the effects of the dry needling and the laser in the treatment of upper trapezius trigger point on women. This study is composed of an evaluation and an intervention proposal with dry needling and LLLT to treat

2017 Clinical Trials

93. Tissue resident memory T cells in the human conjunctiva and immune signatures in human dry eye disease Full Text available with Trip Pro

Tissue resident memory T cells in the human conjunctiva and immune signatures in human dry eye disease Non-recirculating resident memory (TRM) and recirculating T cells mount vigorous immune responses to both self and foreign antigens in barrier tissues like the skin, lung and gastrointestinal tract. Using impression cytology followed by flow cytometry we identified two TRM subsets and four recirculating T-subsets in the healthy human ocular surface. In dry eye disease, principal component (...) -based characterization of dry eye disease and T-subset specific immunotherapies to suppress T-subsets involved in disease. They may also help with patient stratification during clinical trials of immunomodulators.

2017 Scientific reports

94. An Overt Chemical Protective Garment Reduces Thermal Strain Compared with a Covert Garment in Warm-Wet but Not Hot-Dry Environments Full Text available with Trip Pro

An Overt Chemical Protective Garment Reduces Thermal Strain Compared with a Covert Garment in Warm-Wet but Not Hot-Dry Environments Objectives: A commercial chemical, biological, radiological and nuclear (CBRN) protective covert garment has recently been developed with the aim of reducing thermal strain. A covert CBRN protective layer can be worn under other clothing, with equipment added for full chemical protection when needed. However, it is unknown whether the covert garment offers any (...) in mean body temperature and mean skin temperature was greater in COVERT (0.025[0.004] and 0.045[0.010]°C·min-1, respectively) compared with OVERT (0.014[0.004] and 0.027[0.007]°C·min-1, respectively) in WarmWet (P < 0.001 and P = 0.028, respectively). However, the rate of change in mean body temperature and mean skin temperature was greater in OVERT (0.068[0.010] and 0.170[0.026]°C·min-1, respectively) compared with COVERT (0.059[0.004] and 0.120[0.017]°C·min-1, respectively) in HotDry (P = 0.002

2017 Frontiers in physiology

95. COMPARISON OF DRY NEEDLING VS. SHAM ON THE PERFORMANCE OF VERTICAL JUMP Full Text available with Trip Pro

to participate in this study (mean age 22.7+/- 2.4 years). The subjects were randomly divided into two groups- dry needling (n=18) vs sham (n=17). The dry needling group received needling to four sites on bilateral gastrocnemius muscles; two at the medial head and two at the lateral head. The sham group had the four areas of the gastrocnemius muscle pressed with the tube housing the needle, but the needle was never inserted into the skin. Two-legged vertical jump was measured with chalk marks on the wall (...) COMPARISON OF DRY NEEDLING VS. SHAM ON THE PERFORMANCE OF VERTICAL JUMP Dry needling has been reported to decrease pain in subjects having myofascial trigger points, as well as pain in muscle and connective tissue.The purpose of the study was to compare the effects on the ability to perform a two-legged vertical jump between a group who received one bout of dry needling and a group who received one bout of a sham treatment.Thirty-five healthy students (19 males, 16 females) were recruited

2017 International journal of sports physical therapy Controlled trial quality: uncertain

96. Intense pulsed light for evaporative dry eye disease Full Text available with Trip Pro

Intense pulsed light for evaporative dry eye disease There is a clear association between dry eye disease (DED) and skin inflammatory diseases occurring in close proximity to the eyelids, such as facial skin rosacea. Intense pulsed light (IPL) is widely accepted as a treatment for skin rosacea. A number of recent studies demonstrated that, in patients suffering from meibomian gland dysfunction (MGD), IPL therapy also reduces signs and symptoms of DED. Despite these encouraging results

2017 Clinical ophthalmology (Auckland, N.Z.)

97. Effectiveness of Intense Pulsed Light for Improving Dry Eye Syndrome

. Since during treatment both eyes of the subject will be fully occluded, no subject will be able to see if the treatment is actual or sham. There is no way to completely mask the subjects, since the IPL generally causes slight redness of the skin, and in some patients is may also cause some discomfort Primary Purpose: Treatment Official Title: Effectiveness of Intense Pulsed Light for Improving Signs and Symptoms of Dry Eye Disease Due to Meibomian Gland Dysfunction Actual Study Start Date : January (...) Effectiveness of Intense Pulsed Light for Improving Dry Eye Syndrome Effectiveness of Intense Pulsed Light for Improving Dry Eye Syndrome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effectiveness

2017 Clinical Trials

98. IPL and MGX Versus MGX Alone in the Treatment of Dry Eye Disease Secondary to MGD

IPL and MGX Versus MGX Alone in the Treatment of Dry Eye Disease Secondary to MGD IPL and MGX Versus MGX Alone in the Treatment of Dry Eye Disease Secondary to MGD - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding (...) more. IPL and MGX Versus MGX Alone in the Treatment of Dry Eye Disease Secondary to MGD The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03265652 Recruitment Status : Not yet recruiting First Posted : August 29, 2017 Last

2017 Clinical Trials

99. Changes in Surface EMG Activity After Dry Needling Compared to Sham Needling

/treatment Experimental: Dry needling A single dry needling session will be performed with the subject lying on the non painful side. After palpation of a taut band, and detection of a MTrP in the upper trapezius muscle, a trained physiotherapist will penetrate the needle into skin surface, fascia, into the muscle tissue at the MTrP location, and will move the needle up and down in multiple directions. In case local twitch responses are elicited, this will be repeated until the local twitch responses (...) Changes in Surface EMG Activity After Dry Needling Compared to Sham Needling Changes in Surface EMG Activity After Dry Needling Compared to Sham Needling - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2017 Clinical Trials

100. Dry Needling on the Treatment of Chronic Somatosensory Tinnitus: An Open Pilot Study

Dry Needling on the Treatment of Chronic Somatosensory Tinnitus: An Open Pilot Study Dry Needling on the Treatment of Chronic Somatosensory Tinnitus: An Open Pilot Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Dry Needling on the Treatment of Chronic Somatosensory Tinnitus: An Open Pilot Study The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03295890 Recruitment Status : Recruiting First Posted : September 28, 2017

2017 Clinical Trials

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