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Dry Mouth

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121. Dry Eye Disease Patients with Xerostomia Report Higher Symptom Load and Have Poorer Meibum Expressibility (PubMed)

Dry Eye Disease Patients with Xerostomia Report Higher Symptom Load and Have Poorer Meibum Expressibility The purpose of the study was to investigate if xerostomia (dry mouth) is associated with symptoms and signs of dry eye disease (DED). At the Norwegian Dry Eye Clinic, patients with symptomatic DED with different etiologies were consecutively included in the study. The patients underwent a comprehensive ophthalmological work-up and completed self-questionnaires on symptoms of ocular dryness (...) (Ocular Surface Disease Index [OSDI] and McMonnies Dry Eye Questionnaire) and the Sjögren's syndrome (SS) questionnaire (SSQ). Three hundred and eighteen patients (52% women and 48% men) with DED were included. Patient demographics were: 0 to 19 years (1%), 20 to 39 (25%), 40 to 59 (34%), 60 to 79 (35%) and 80 to 99 (5%). Xerostomia, defined as "daily symptoms of dry mouth the last three months" (as presented in SSQ) was reported by 23% of the patients. Female sex was more common among patients

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2016 PloS one

122. Optical Coherence Tomography of Ocular Structures in Epiphora and Dry Eye Syndrome.

Optical Coherence Tomography of Ocular Structures in Epiphora and Dry Eye Syndrome. Optical Coherence Tomography of Ocular Structures in Epiphora and Dry Eye Syndrome. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Optical Coherence Tomography of Ocular Structures in Epiphora and Dry Eye Syndrome. (OCT) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02849093 Recruitment Status : Unknown Verified July 2016 by Bedford Hospital NHS Trust. Recruitment status was: Active, not recruiting First Posted

2016 Clinical Trials

123. Dry socket – oral contraceptives may increase incidence

osteitis) is not fully understood and a number of factors have been implicated including surgical trauma, surgeons experience, perioperative patient stress factors and focal fibrinolytic activity. A number of additional risk factors including smoking, age, gender and oral contraceptive use, menstrual cycle and the use of antimicrobial drugs and mouth rinses have also been suggested. The aim of this review was to assess the association between oral contraceptive use and the development of dry socket (...) Dry socket – oral contraceptives may increase incidence Dry socket: oral contraceptives may increase incidence Search National Elf Service Search National Elf Service » » » » Dry socket – oral contraceptives may increase incidence Jul 16 2015 Posted by Dry Socket is a complication that can follow tooth extraction occurring in 1%- 5% of routine extractions. It is more common following the extraction of third molars with rates of between 1% – 37% reported. The aetiology of dry socket (alveolar

2015 The Dental Elf

124. A Preference Study of Two Placebo Dry Powder Inhalers in Adults with COPD: ELLIPTA® Dry Powder Inhaler (DPI) versus DISKUS® DPI. (PubMed)

'). Safety assessments included adverse events (AEs). A total of 287 patients were randomized. A significantly (p < 0.001) larger proportion of patients preferred the ELLIPTA DPI over DISKUS DPI for each of the tested attributes and overall, and preferred once-daily over twice-daily dosing. AEs were reported for 36 patients (13%); one (dry mouth) was considered to be related to the placebo-containing DISKUS DPI. Three patients had five non-fatal serious AEs, none were deemed inhaler-related. This study (...) A Preference Study of Two Placebo Dry Powder Inhalers in Adults with COPD: ELLIPTA® Dry Powder Inhaler (DPI) versus DISKUS® DPI. Patients' preference is an important factor in selecting an inhaler treatment for COPD. The DISKUS® dry powder inhaler (DPI), which has been available to deliver several COPD medications for a decade, and the ELLIPTA® DPI, developed for the delivery of newer once-daily medications for patients with COPD, were studied in terms of patient preference and inhaler

2015 COPD

125. Interventions for the management of dry mouth: topical therapies. (PubMed)

Interventions for the management of dry mouth: topical therapies. Xerostomia (the feeling of dry mouth) is a common symptom especially in older adults. Causes of dry mouth include medications, autoimmune disease (Sjögren's Syndrome), radiotherapy or chemotherapy for cancer, hormone disorders and infections.To determine which topical treatments for dry mouth are effective in reducing this symptom.We searched the following electronic databases: the Cochrane Oral Health Group Trials Register (28 (...) their use. Although chewing gum is associated with increased saliva production in the majority of those with residual capacity, there is no evidence that gum is more or less effective than saliva substitutes.There is no strong evidence from this review that any topical therapy is effective for relieving the symptom of dry mouth. OGT spray is more effective than an aqueous electrolyte spray (SMD 0.77, 95% CI 0.38 to 1.15) which is approximately equivalent to a mean difference of 2 points on a 10-point

2011 Cochrane database of systematic reviews (Online)

126. A comparison of salivary substitutes versus a natural sialogogue (citric acid) in patients complaining of dry mouth as an adverse drug reaction: a clinical, randomized controlled study. (PubMed)

A comparison of salivary substitutes versus a natural sialogogue (citric acid) in patients complaining of dry mouth as an adverse drug reaction: a clinical, randomized controlled study. We aimed to compare the efficacy of saliva substitutes and citric acid long-term therapy for oral dryness relief and unstimulated salivary flow in patients reporting drug-induced xerostomia.Fifty-four patients reporting drug-induced xerostomia were randomly subdivided into 3 groups and respectively administered

2011 Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics

127. Summary of: Treating patients with dry mouth: general dental practitioners' knowledge, attitudes and clinical management. (PubMed)

Summary of: Treating patients with dry mouth: general dental practitioners' knowledge, attitudes and clinical management. 22116236 2012 04 27 2011 11 25 1476-5373 211 10 2011 Nov 25 British dental journal Br Dent J Summary of: Treating patients with dry mouth: general dental practitioners' knowledge, attitudes and clinical management. 474-5 10.1038/sj.bdj.2011.986 Thomson W M WM Sir John Walsh Research Institute, The University of Otago, Dunedin, New Zealand. eng Comment Journal Article 2011 11

2011 British Dental Journal

128. Treating patients with dry mouth: general dental practitioners' knowledge, attitudes and clinical management. (PubMed)

Treating patients with dry mouth: general dental practitioners' knowledge, attitudes and clinical management. To assess primary care dental practitioners' knowledge, attitudes and clinical management of patients presenting with dry mouth.A convenience sample of 200 dentists working in primary care in an NHS Health Board in Scotland was obtained. A questionnaire to assess knowledge, attitudes and clinical management of dry mouth patients was sent to all dentists on the NHS primary care service (...) inventory. Ethical approval was obtained.Two hundred questionnaires were sent to the participants and 114 were returned, giving a valid response rate of 58%. Fifty percent were woman and 80% worked in the general dental service. Seventy-nine percent had been taught about xerostomia as undergraduates but only 21% had postgraduate educational experiences of dry mouth. The majority correctly stated that patients with Sjögren's syndrome would have an increased risk of dental caries, oral candidosis

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2011 British Dental Journal

129. Dry mouth and dietary quality in older adults in north Carolina. (PubMed)

Dry mouth and dietary quality in older adults in north Carolina. To quantify prevalence of dry mouth, association between dry mouth and beverage intake and dietary quality, and association between dry mouth and self-reported dietary accommodations to oral health deficits.Cross-sectional study; data from self-reports.Rural North Carolina counties with substantial African-American and American Indian populations.Six hundred twenty-two participants aged 60 and older.Data included the 11-item (...) Xerostomia Inventory (higher scores connote greater effect from dry mouth), a food frequency questionnaire (converted into Health Eating Index-2005 scores), and survey items on foods modified before consumption or avoided because of oral health problems.Dry mouth was associated with being female, lower education, and income below the poverty level. Although overall beverage consumption did not vary with dry mouth, consumption of certain sugar-sweetened beverages was positively associated with dry mouth

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2011 Journal of the American Geriatrics Society

130. Observational Study to Estimate the Dry Mouth in OAB Patients With Solifenacin

Observational Study to Estimate the Dry Mouth in OAB Patients With Solifenacin Observational Study to Estimate the Dry Mouth in OAB Patients With Solifenacin - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Observational Study to Estimate the Dry Mouth in OAB Patients With Solifenacin (OAB) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01437670 Recruitment Status : Completed First Posted : September 21, 2011 Last Update Posted : May 30, 2014 Sponsor: Asan Medical Center Collaborators: Samsung Medical Center

2011 Clinical Trials

131. Managing the Edentulous Dry Mouth: The Two Part Mandibular Denture (PubMed)

Managing the Edentulous Dry Mouth: The Two Part Mandibular Denture Treatment of patients suffering from xerostomia can be a challenge and more so in the completely edentulous. The difficulties encountered can be troublesome and at times may lead to complete failure of the prosthesis. Xerostomia may occur due to a number of reasons. Here is a report of an attempt at the fabrication of complete denture in one such case. The technique involves incorporation of a salivary reservoir in the denture

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2011 The Journal of the Indian Prosthodontic Society

132. Freeze-Drying of Foot-and-Mouth Disease Virus and Storage Stability of the Infectivity of Dried Virus at 4 C (PubMed)

Freeze-Drying of Foot-and-Mouth Disease Virus and Storage Stability of the Infectivity of Dried Virus at 4 C Foot-and-mouth disease virus, type A, strain 119, propagated in cultures of calf kidney cells and in the tongue epithelium of cattle was used. The process of freeze-drying was conducted in two cycles on unit volumes of 4 ml in Pyrex ampoules, averaging 150 ampoules per run, and was studied separately from the problems of storage. Ampoules containing freeze-dried virus were flame-sealed (...) while stored at 4 C for 1 year. Virus in four freeze-dried tissue suspensions had a mean loss of 0.05 log LD(50) per ml held at 4 C for 1 year. None of the specific additives used for conservation of the virus during the freeze-drying process or during storage at 4 C contributed significantly to the stability of the virus preparations over and above that observed with the normal growth medium of the tissue culture or the ordinary diluents used in making suspensions of tissue virus.

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1965 Applied microbiology

133. Dry mouth (Xerostomia)

Dry mouth (Xerostomia) Palliative Care Guidelines Plus Please select the region you work in: England - London England - South East England - South West England - East of England England - East Midlands England - West Midlands England - Yorkshire and the Humber England - North East England - North West Wales Northern Ireland Scotland Outside the UK Please select the country: US Canada New Zealand Ireland Other Enter site I am a doctor/physician I am a healthcare professional I am

2010 Palliative Medicine Handbook

134. Use of Biotene Moisturizing Mouth Spray for Xerostomia Associated With Oral Oxybutynin Use

Intervention/treatment Phase Overactive Bladder Xerostomia Compliance Drug: Biotene oral spray Phase 4 Detailed Description: Overactive bladder (OAB) is a common condition affecting roughly 20% of women. Anticholinergic medications are the main treatment modality for women with OAB; however, treatment is hampered by high rates of dry mouth which limit tolerability. Discontinuation rates for anticholinergic medications for dry mouth have been reported to be as high as 71% at 6 months. Biotène(TM (...) as measured by patient report [ Time Frame: 3 months ] Discontinuation rate of oxybutynin at 3 months as measured by pill count [ Time Frame: 3 months ] Symptoms of dry mouth as measured by global xerostomia question [ Time Frame: 3 months ] Number of daily voids as measured by voiding diary [ Time Frame: 3 months ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members

2015 Clinical Trials

135. Association between Mouth Breathing and Atopic Dermatitis in Japanese Children 2–6 years Old: A Population-Based Cross-Sectional Study (PubMed)

at 13 nurseries in Tokushima City. There were 468 valid responses (45.2%). We defined a subject as a mouth breather in daytime (MBD) if they had 2 or more positive items among the 3 following items: "breathes with mouth ordinarily," "mouth is open ordinarily," and "mouth is open when chewing." We defined subjects as mouth breathers during sleep (MBS) if they had 2 or more positive items among the following 3 items: "snoring," "mouth is open during sleeping," and "mouth is dry when your child gets up (...) Association between Mouth Breathing and Atopic Dermatitis in Japanese Children 2–6 years Old: A Population-Based Cross-Sectional Study As mouth breathing is associated with asthma and otitis media, it may be associated with other diseases. Therefore, this population-based cross-sectional study evaluated the association of mouth breathing with the prevalences of various diseases in children. Preschool children older than 2 years were included. A questionnaire was given to parents/guardians

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2015 PloS one

136. Effect of vaccination against foot-and-mouth disease on growth performance of Korean native goat (Capra hircus coreanae). (PubMed)

Effect of vaccination against foot-and-mouth disease on growth performance of Korean native goat (Capra hircus coreanae). The objectives of this study were 1) to evaluate the effects of vaccination against foot-and-mouth disease (FMD) on growth performance, nutrient digestibility, hematological parameters, and behavior in a ruminant animal and 2) to investigate a possible strategy for reducing its adverse effect. A total of 12 Korean native goats (Capra hircus coreanae; 19.8 ± 2.9 kg) were used (...) with a diet consisting of bermuda grass and commercial concentrate mix (6:4, wt/wt). Dry matter intake, ADG, nutrients digestibility, hematological parameters, and behavioral activities of the goats were measured before and after vaccination. Although DMI was not decreased (P > 0.05), ADG was decreased by the vaccination to the goats (P < 0.01). The total number of leukocytes was increased while that of erythrocytes was decreased by the FMD vaccination (P < 0.01). The vaccination shortened standing time

2014 Journal of animal science

137. Reduction in unstimulated salivary flow rate in burning mouth syndrome. (PubMed)

side effects include dry mouth. This suggests that hyposalivation may play a role in causing dry mouth in BMS, which may respond to treatment with a sialogogue. (...) Reduction in unstimulated salivary flow rate in burning mouth syndrome. Burning mouth syndrome (BMS) is a chronic condition of burning of the tongue and oral mucosa. It is often accompanied with complaints of xerostomia, although it is unknown whether the dryness is a sensory change similar to the burning sensation or due to hyposalivation. To determine whether there is change in salivary flow rate, whole salivary flows were measured in BMS patients.A clinical ambispective study was conducted

2014 British Dental Journal

138. A New Oral salIvary equivAlent Compared to Two moisturizinG Mouth sprAys in Patients With xeRostomiA: NIAGARA Study

(Clinical Trial) Actual Enrollment : 210 participants Allocation: Randomized Intervention Model: Crossover Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Phase 4 Study Evaluating Efficacy, Safety and Acceptability of Treatment With a New Salivary Equivalent Compared to Two Moisturizing Mouth Sprays on the Improvement of Dry Mouth Symptoms and Oral Comfort in Patients With Xerostomia. Study Start Date : January 2012 Actual Primary Completion Date : April 2013 Actual (...) Comparator: Biotene Multidose moisturizing oral spray without any active substance Device: Biotene 14-day treatment with Biotene oral spray Outcome Measures Go to Primary Outcome Measures : Dry mouth discomfort [ Time Frame: 14 days ] Patient evaluation through the completion of a self rated 100 mm long VAS score. Anchor points of the VAS score will be 0 representing the absence of any dry mouth symptoms and 100 representing the worst imaginable picture of dry mouth discomfort Secondary Outcome Measures

2014 Clinical Trials

139. A split-mouth randomized clinical trial to evaluate the performance of piezosurgery compared with traditional technique in lower wisdom tooth removal. (PubMed)

difference after 4 days (P = .043). The clinical value of orofacial swelling at day 7, normalized to baseline, was lower in the piezosurgery group (P < .005). The average surgical duration was significantly shorter in the bur group than in the piezosurgery group (P < .05). Three patients having bur removal developed short-term complications (2 dry sockets and 1 temporary paraesthesia), which totally resolved by 4 weeks.To date, this prospective investigation is the largest reported split-mouth study (...) A split-mouth randomized clinical trial to evaluate the performance of piezosurgery compared with traditional technique in lower wisdom tooth removal. The surgical removal of mandibular third molars is frequently accompanied by significant postsurgical sequelae, and different protocols have been described to decrease such adverse events. The aim of this study was to investigate the performance of piezosurgery compared with traditional rotating instruments during mandibular third molar removal.A

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2014 Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

140. An Extension Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome

Syndrome Keratoconjunctivitis Sicca Dry Eye Syndromes Sjogren's Syndrome Disease Pathologic Processes Keratoconjunctivitis Conjunctivitis Conjunctival Diseases Eye Diseases Keratitis Corneal Diseases Lacrimal Apparatus Diseases Arthritis, Rheumatoid Arthritis Joint Diseases Musculoskeletal Diseases Rheumatic Diseases Xerostomia Salivary Gland Diseases Mouth Diseases Stomatognathic Diseases Connective Tissue Diseases Autoimmune Diseases Immune System Diseases Ophthalmic Solutions Pharmaceutical (...) An Extension Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome An Extension Study of KCT-0809 in Dry Eye Patients With Sjögren's Syndrome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2015 Clinical Trials

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