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Dry Mouth

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81. Effect of Resveratrol Dry Suspension on Immune Function of Piglets. Full Text available with Trip Pro

Effect of Resveratrol Dry Suspension on Immune Function of Piglets. Resveratrol, a polyphenolic plant antitoxin, has a wide range of pharmacological activities. In this study, we systematically evaluated the effects of resveratrol dry suspension (RDS) on immune function in piglets that were treated with different doses of RDS for 2 weeks. The results showed that the RDS has significant effects on the development, maturation, proliferation, and transformation of T lymphocytes. RDS could regulate (...) humoral immune responses by upregulating the release of IFN-γ and downregulating the release of TNF-α. After piglets were vaccinated against classical swine fever virus and foot-and-mouth disease virus, the antibody titers were significantly increased. RDS treatment showed an excellent resistance to enhance T-SOD activity. Values of blood routine and blood biochemistry showed no toxicity. These results suggested that RDS could be considered as an adjuvant to enhance immune responses to vaccines

2018 Evidence-based Complementary and Alternative Medicine (eCAM)

82. Prerequisites for a dry powder inhaler for children with cystic fibrosis. Full Text available with Trip Pro

Prerequisites for a dry powder inhaler for children with cystic fibrosis. Correct inhalation technique is essential for effective use of dry powder inhalers (DPIs), as their effectiveness largely depends on the patient's inhalation manoeuvre. Children are an especially challenging target population for DPI development due to the large variability in understanding and inspiratory capacities. We previously performed a study in which we determined the prerequisites for a paediatric DPI in a mostly (...) in the mouth during inhalation were recorded with a sinuscope. All children were able to perform a correct inhalation manoeuvre, although video analysis showed that children did not place the inhaler correctly in the mouth in 17% of the cases. No effect was found of medium to high airflow resistance on total inhaled volume, which implies that the whole resistance range tested is suitable for children with CF aged 4-14 years. No effect could be established of either mouthpiece design or airflow resistance

2017 PLoS ONE

83. Insufficient evidence for effects of non-pharmacological interventions for the relief of dry mouth

Insufficient evidence for effects of non-pharmacological interventions for the relief of dry mouth Insufficient evidence for effects of non-pharmacological interventions for the relief of dry mouth Search National Elf Service Search National Elf Service » » » » Insufficient evidence for effects of non-pharmacological interventions for the relief of dry mouth Sep 3 2013 Posted by It has been estimated that between 10-26% of men and 10-33% of women experience dry mouth. The subjective sensation (...) of dry mouth is called xerostomia and can be found in people with normal salivary gland function. The normal range of salivary production ranges from 0.5 to 1.5 litres per day. The aim of this Cochrane review was to assess the effects of non-pharmacological interventions administered to stimulate saliva production for the relief of dry mouth. Searches were conducted in the Cochrane Oral Health Group’s Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, AMED

2013 The Dental Elf

84. Information for Physicians and Pharmacists About Drugs That Might Cause Dry Mouth: A Study of Monographs and Published Literature. (Abstract)

Information for Physicians and Pharmacists About Drugs That Might Cause Dry Mouth: A Study of Monographs and Published Literature. Over three-quarters of the older population take medications that can potentially cause dry mouth. Physicians or pharmacists rarely inform patients about this adverse effect and its potentially severe damage to the teeth, mouth and general health.The objectives of this study were to (1) identify warnings in the literature about dry mouth associated with the most (...) journals.The CPS provided monographs for 43% of the medications, and requests to manufacturers produced the remaining monographs. Mentions of dry mouth were identified in 61% of the products (43% amongst CPS monographs; an additional 43% amongst manufacturers' monographs; 7% in the DailyMed database and 7% from biomedical journals); five medications had contradictory reports in different monographs.Nearly two-thirds (61%) of the most commonly prescribed medications can cause dry mouth, yet warnings about

2013 Drugs & Aging

85. Effects of Intra-alveolar Placement of 0.2% Chlorhexidine Bioadhesive Gel on Dry Socket Incidence and Postsurgical Pain: A Double-Blind Split-Mouth Randomized Controlled Clinical Trial. Full Text available with Trip Pro

Effects of Intra-alveolar Placement of 0.2% Chlorhexidine Bioadhesive Gel on Dry Socket Incidence and Postsurgical Pain: A Double-Blind Split-Mouth Randomized Controlled Clinical Trial. To assess the effects of intra-alveolar application of chlorhexidine gel on the incidence of alveolar osteitis (dry socket) and the severity of postsurgical pain.A total of 160 impacted mandibular third molars were extracted in 80 patients enrolled in this trial. In each subject, a socket was randomly selected (...) and packed to the crest of the alveolar ridge with a gelatin sponge dressing saturated in 0.2% chlorhexidine gel. The contralateral socket was packed with a dry dressing as the placebo. None of the included patients took antibiotics or analgesics. The occurrence of dry socket and patients' pain levels were assessed at the first and third postoperative days. The data were analyzed using Spearman correlation coefficient, McNemar, Wilcoxon, and chi-square tests.Chlorhexidine gel significantly reduced dry

2013 Journal of orofacial pain Controlled trial quality: uncertain

86. The efficacy of a topical sialogogue spray containing 1% malic Acid in patients with antidepressant-induced dry mouth: a double-blind, randomized clinical trial. (Abstract)

The efficacy of a topical sialogogue spray containing 1% malic Acid in patients with antidepressant-induced dry mouth: a double-blind, randomized clinical trial. One of the most important antidepressants side effects is dry mouth. The aim of this study was to evaluate the clinical efficacy of a topical sialogogue spray containing 1% malic acid on patients affected by dry mouth caused by antidepressants drug.This research took the form of a double-blind, randomized clinical trial at Faculty (...) of Dentistry of University of Granada (Spain). Seventy participants with antidepressant-induced dry mouth were divided into two groups: for the first "intervention group" (35 subjects) a topical sialogogue spray (1% malic acid) was applied, while for the second "control group" (35 subjects), a placebo spray was applied; for both groups, the sprays were applied on demand during 2 weeks. The dry mouth questionnaire (DMQ) was used to evaluate dry mouth symptoms before and after product/placebo application

2013 Depression and anxiety Controlled trial quality: uncertain

87. Xylitol Disk Use in Adults With Dry Mouth

Xylitol Disk Use in Adults With Dry Mouth Xylitol Disk Use in Adults With Dry Mouth - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Xylitol Disk Use in Adults With Dry Mouth The safety and scientific (...) : The purpose of this study is to demonstrate whether decay causing bacteria are reduced when adhesive xylitol disks are used intraorally three times a day for two weeks in adults with dry mouth. Condition or disease Intervention/treatment Phase Mutans Streptococci Xerostomia Other: Xylitol disk Not Applicable Detailed Description: Xylitol,an FDA approved sugar substitute, has been shown to reduce tooth decay. Patients who experience dry mouth may be more susceptible to dental decay because they lack

2013 Clinical Trials

88. Laser Therapy to Treat the Dry Mouth of Sjogren's Syndrome

Laser Therapy to Treat the Dry Mouth of Sjogren's Syndrome Laser Therapy to Treat the Dry Mouth of Sjogren's Syndrome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Laser Therapy to Treat the Dry Mouth (...) feels dry when eating a meal I get up at night to drink My mouth feels dry I have difficulty in eating dry foods I suck sweets or cough lollies to relieve dry mouth I have difficulties swallowing certain foods The skin of my face feels dry My eyes feel dry My lips feel dry The inside of my nose feels dry __________________________________________________________ Score: Never' (1), Hardly ever' (2), Occasionally' (3), Fairly often' (4), Very often' (5) Secondary Outcome Measures : Salivary Biomarker

2013 Clinical Trials

89. Do pilocarpine drops help dry mouth in palliative care patients: a protocol for an aggregated series of n-of-1 trials. Full Text available with Trip Pro

Do pilocarpine drops help dry mouth in palliative care patients: a protocol for an aggregated series of n-of-1 trials. It is estimated that 39,000 Australians die from malignant disease yearly. Of these, 60% to 88% of advanced cancer patients suffer xerostomia, the subjective feeling of mouth dryness. Xerostomia has significant physical, social and psychological consequences which compromise function and quality of life. Pilocarpine is one treatment for xerostomia. Most studies have shown some (...) variation in individual response to pilocarpine, in terms of dose used, and timing and extent of response.We will determine a population estimate of the efficacy of pilocarpine drops (6 mg) three times daily compared to placebo in relieving dry mouth in palliative care (PC) patients. A secondary aim is to assess individual patients' response to pilocarpine and provide reports detailing individual response to patients and their treating clinician.Aggregated n-of-1 trials (3 cycle, double blind, placebo

2013 BMC Palliative Care Controlled trial quality: uncertain

90. Influence of Mouth Breathing on Periodontal Healing

provided by (Responsible Party): Postgraduate Institute of Dental Sciences Rohtak Study Details Study Description Go to Brief Summary: Studies reveal association between dry conditions and decreased healing in wounds or any treatment. From these studies, it can be hypothesized that healing in mouth breathers after scaling and root planing in terms of bleeding on probing, gingival index, plaque Index, clinical attachment level, probing depth may not show as much improvement as in case of nose breathers (...) Influence of Mouth Breathing on Periodontal Healing Influence of Mouth Breathing on Periodontal Healing - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Influence of Mouth Breathing on Periodontal Healing

2017 Clinical Trials

91. A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Patients and Patients With Average to Very Serious Psoriasis

: NCT03329885 Recruitment Status : Terminated (Adverse change in the risk/benefit) First Posted : November 6, 2017 Last Update Posted : July 23, 2018 Sponsor: Bristol-Myers Squibb Information provided by (Responsible Party): Bristol-Myers Squibb Study Details Study Description Go to Brief Summary: The purpose of this study is to investigate experimental medication BMS-986251 taken by mouth in healthy patients and patients with average to very serious Psoriasis (a condition characterized by itchy, dry skin (...) A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Patients and Patients With Average to Very Serious Psoriasis A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Patients and Patients With Average to Very Serious Psoriasis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning

2017 Clinical Trials

92. Patients with burning mouth sensations. A clinical investigation of causative factors in a group of “compete denture wearers” Jordanian population Full Text available with Trip Pro

associations were found between local factors (i.e., wearing complete dentures with unsatisfactory retention or jaw relationship, dry mouth or candidasis) and patients suffering from burning mouth sensation. The results also show that some systemic or psychological disorders were significantly more present among patients with burning mouth symptoms when compared to the control group (p < 0.05).Spontaneous symptoms of burning mouth without mucosal signs should be considered as a manifestation of undermind (...) Patients with burning mouth sensations. A clinical investigation of causative factors in a group of “compete denture wearers” Jordanian population To find out the prevalence of "true" burning mouth syndrome and study the association between patients' spontaneous complaints of burning mouth and systemic conditions in a group of middle age and elderly "denture wearers" patients in Jordan.A group of 129 patients (112 female and 17 male) of "complete denture wearers" subjects aged 40 years

2017 The Saudi dental journal

93. Healing of extraction socket following local application of simvastatin: A split mouth prospective study Full Text available with Trip Pro

Healing of extraction socket following local application of simvastatin: A split mouth prospective study The role of simvastatin in lowering serum cholesterol level is well described. However, recent findings suggest they have a role in bone formation as well.The present prospective study was conducted to evaluate the efficacy of simvastatin on bone formation in extraction sockets.15 patients undergoing all four first premolar extraction were selected based on inclusion and exclusion criteria (...) . Extraction sockets of left premolars (24 and 34) were considered as cases and right premolars (14 and 44) as controls. Overall 30 extraction sites were assigned to each group. Atraumatic extraction was done in all cases following which simvastatin mixed with gelatin sponge was placed in extraction socket of 24 and 34 while only gelatin sponge was placed in 14 and 44. All sockets were then closed with 3-0 vicryl. The patients were kept on follow-up and complications such as dry socket, pain, and swelling

2017 Journal of oral biology and craniofacial research

94. Will mouth wash solutions of water, salt, sodiumbicarbonate or citric acid improve upper gastrointestinal symptoms in chronic kidney disease. (Abstract)

Will mouth wash solutions of water, salt, sodiumbicarbonate or citric acid improve upper gastrointestinal symptoms in chronic kidney disease. Uraemic symptoms including taste changes, nausea and dry retching are common in chronic kidney disease (CKD). Taste buds detect five basic tastes: sweet, salty, sour, umami and bitter. Saliva in CKD usually has increased concentrations of urea, sodium, potassium, phosphate and higher pH levels. Genetic sensitivities to the bitter taste, with the changes (...) of salt, bicarbonate, citric acid and de-ionised water were trialled in randomized order for patient reaction and symptom improvement.All 42 patients experienced anorexia, 39 (93%) reported taste changes, 27 (48%) nausea and 27 (48%) dry retching. All solutions improved symptoms in some patients. Sodium bicarbonate (P = 0.005) gave the greatest improvement in mouth feel and symptom control compared with the least favoured citric acid solution. Sixty-six percent of patients found sodium bicarbonate

2017 Nephrology (Carlton, Vic.) Controlled trial quality: uncertain

95. Evidence for the efficacy of clinical methods to assess dry mouth is sparse

Evidence for the efficacy of clinical methods to assess dry mouth is sparse Evidence for the efficacy of clinical methods to assess dry mouth is sparse Search National Elf Service Search National Elf Service » » » » Evidence for the efficacy of clinical methods to assess dry mouth is sparse Aug 10 2012 Posted by Salivary is a complex substance than contains electrolytes, mucus, glycoproteins, enzymes, lysosomes and immunoglobulin. Its normal production is considered important for oral health

2012 The Dental Elf

96. No strong evidence for any topical treatments for relieving the symptoms of dry mouth

No strong evidence for any topical treatments for relieving the symptoms of dry mouth No strong evidence for any topical treatments for relieving the symptoms of dry mouth Search National Elf Service Search National Elf Service » » » » No strong evidence for any topical treatments for relieving the symptoms of dry mouth Jul 11 2012 Posted by The subjective sensation of dry mouth or xerostomia is a common symptom and estimates of the prevalence vary from 10-50%. The Cochrane Collaboration (...) published systematic of topical treatments for reducing the effects of dry mouth in 2011( Furness et al ). Recently the American Dental Association’s Evidence-based Dentistry Center have published a critical summary of this review The summariser notes that the review was of high quality, although, because of the range of interventions and variety of outcome measures only limited meta-analysis could be performed. The review included 36 trials in all, 17 of which were of high risk of bias. 18 of unclear

2012 The Dental Elf

97. Chlorhexidine gels and rinses reduce dry socket after third molar extraction

Chlorhexidine gels and rinses reduce dry socket after third molar extraction Chlorhexidine gels and rinses reduce dry socket after third molar extraction - National Elf Service Search National Elf Service Search National Elf Service » » » » Chlorhexidine gels and rinses reduce dry socket after third molar extraction Mar 13 2017 Posted by Dry socket (alveolar osteitis) is a common post-operative complication of permanent tooth extraction. Incidence of alveolar osteitis (AO) has been reported (...) . The primary outcome was incidence of AO and efficacy summaries using risk ratios (RR), preventive fraction and number needed to treat (NNT). Meta-analysis of binary data was conducted using a fixed-effects model. Result s 18 RCTs (16 parallel-group and 2 split-mouth) were included There were 2,824 third molar extractions (1,458 in experimental group and 1,366 in control group). 10 studies involved rinses, 4 using 0.2% concentration others 0.12%. 10 studies used gels, most using 0.2% concentration, 1 using

2017 The Dental Elf

98. Dry Mouth

Dry Mouth Dry Mouth Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Dry Mouth Dry Mouth Aka: Dry Mouth , Xerostomia , Salivary (...) % Fluoride gel daily Fluoride toothpaste Fluoride rinses Scrupulous dental care is essential See Dentist regularly stimulation Sugar-free chewing gum (esp. Xylitol containing gums) Lemon lozenges Consider s in severe refractory Xerostomia of ( ) ( ) VI. References Daniels in Goldman (2000) Cecil Medicine, p. 2245 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Dry Mouth." Click on the image (or right click) to open the source website

2015 FP Notebook

99. Medication Causes of Dry Mouth

Medication Causes of Dry Mouth Medication Causes of Dry Mouth Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Medication Causes of Dry (...) Mouth Medication Causes of Dry Mouth Aka: Medication Causes of Dry Mouth , Medication Causes of Dry Eyes From Related Chapters II. Causes: Psychiatric medications s s ( ) ( ) s s ( s) ADHD s III. Causes: Upper Respiratory Medications s (e.g. ) s s IV. Causes: Antihypertensives s (e.g. ) (e.g. ) s (e.g. ) s V. Causes: Miscellaneous medications and drugs Muscle relaxants and antispasmodics s Cannabinoids s Antiparkinsonian agents s (e.g. ) VI. References Images: Related links to external sites (from

2015 FP Notebook

100. Evaluate the Efficacy and Safety of LO2A Eye Drops for Symptomatic Improvement of Dry Eye in Patients With Sjögren's Syndrome

Evaluate the Efficacy and Safety of LO2A Eye Drops for Symptomatic Improvement of Dry Eye in Patients With Sjögren's Syndrome Evaluate the Efficacy and Safety of LO2A Eye Drops for Symptomatic Improvement of Dry Eye in Patients With Sjögren's Syndrome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached (...) the maximum number of saved studies (100). Please remove one or more studies before adding more. Evaluate the Efficacy and Safety of LO2A Eye Drops for Symptomatic Improvement of Dry Eye in Patients With Sjögren's Syndrome The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our

2017 Clinical Trials

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