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Dry Mouth

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61. Evaluation of Efficacy of an Herbal Compound on Dry Mouth in Patients With Head and Neck Cancers: A Randomized Clinical Trial. (PubMed)

Evaluation of Efficacy of an Herbal Compound on Dry Mouth in Patients With Head and Neck Cancers: A Randomized Clinical Trial. Dry mouth is a common complication of radiotherapy for head and neck cancers. This study compared the efficacy of an herbal compound containing Malva sylvestris and Alcea digitata (Boiss) with artificial saliva (Hypozalix) for improving the symptoms of dry mouth in head and neck cancer patients. The study examined a total of 62 subjects assigned to 2 groups. The herbal (...) compound and Hypozalix were administered for 4 weeks. Efficacy was assessed using the visual analog scale and by grading the degree of dry mouth. Both groups showed a significant difference between visual analog scale before and following intervention. There was also a significant difference in visual analog scale between groups at 4 weeks after onset of intervention. The herbal group showed a significant difference between the grade of dry mouth before and after intervention, but no change

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2015 Journal of evidence-based complementary & alternative medicine

62. Chlorhexidine gel and less difficult surgeries might reduce post-operative pain, controlling for dry socket, infection and analgesic consumption: a split-mouth controlled randomised clinical trial. (PubMed)

Chlorhexidine gel and less difficult surgeries might reduce post-operative pain, controlling for dry socket, infection and analgesic consumption: a split-mouth controlled randomised clinical trial. Reports on post-surgical pain are a few, controversial and flawed (by statistics and analgesic consumption). Besides, it is not known if chlorhexidine can reduce post-extraction pain adjusting for its effect on prevention of infection and dry socket (DS). We assessed these. A total of 90 impacted (...) mandibular third molars of 45 patients were extracted. Intra-alveolar 0·2% chlorhexidine gel was applied in a split-mouth randomised design to one-half of the sockets. None of the included patients took antibiotics or analgesics afterwards. In the first and third post-operative days, DS formation and pain levels were recorded. Predictive roles of the risk factors were analysed using fixed-effects (classic) and multilevel (mixed-model) multiple linear regressions (α = 0·05, β≤0·1). In the first day, pain

2015 Journal of oral rehabilitation

63. Limited evidence for non-pharmacological interventions for the relief of dry mouth. (PubMed)

Limited evidence for non-pharmacological interventions for the relief of dry mouth. The Cochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, AMED, CINAHL and CANCERLIT databases were searched. The metaRegister of Controlled Clinical Trials and ClinicalTrials.gov were also searched to identify ongoing and completed trials. Reference lists of included studies and relevant reviews were also searched. There were no restrictions (...) on the language of publication or publication status.Randomised controlled trials of non-pharmacological treatments for patients with dry mouth at baseline.Study assessment and data extraction were carried out independently by at least two reviewers. Mean difference (MD) and standardised mean differences (SMD) together with 95% CIs were calculated where appropriate.Nine studies (366 participants) were included in this review, eight were assessed at high risk of bias and one at unclear risk of bias. Five small

2014 Evidence Based Dentistry

64. [Prognosis and treatment of dry mouth. Systematic review.] (PubMed)

[Prognosis and treatment of dry mouth. Systematic review.] There are no clearly established protocols for the treatment of dry mouth. The aim of this paper is a systematic review of the literature of the past 10 years using the words « dry mouth », « prognosis », « treatment » and « dentistry ». The initial search found 1,450 entries and within the restriction « clinical trials OR randomized controlled trial OR systemic reviews » it has been reduced to 522, which 145 were meta-analysis

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2014 Medicina clinica

65. A randomized clinical trial of an intervention to relieve thirst and dry mouth in intensive care unit patients. (PubMed)

A randomized clinical trial of an intervention to relieve thirst and dry mouth in intensive care unit patients. To test an intervention bundle for thirst intensity, thirst distress, and dry mouth, which are among the most pervasive, intense, distressful, unrecognized, and undertreated symptoms in ICU patients, but for which data-based interventions are lacking.This was a single-blinded randomized clinical trial in three ICUs in a tertiary medical center in urban California. A total of 252 (...) cognitively intact patients reporting thirst intensity (TI) and/or thirst distress (TD) scores ≥3 on 0-10 numeric rating scales (NRS) were randomized to intervention or usual care groups. A research team nurse (RTN#1) obtained patients' pre-procedure TI and TD scores and reports of dry mouth. She then administered a thirst bundle to the intervention group: oral swab wipes, sterile ice-cold water sprays, and a lip moisturizer, or observed patients in the usual care group. RTN#2, blinded to group assignment

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2014 Intensive Care Medicine

66. Managing the care of patients with Sjögren syndrome and dry mouth: Comorbidities, medication use and dental care considerations. (PubMed)

Managing the care of patients with Sjögren syndrome and dry mouth: Comorbidities, medication use and dental care considerations. As North Americans live longer, have more chronic conditions and take more medications, adverse oral events are likely to increase and aggravate the symptoms of Sjögren syndrome (SS).A total of 151 adults who self-reported having SS and who had a mean (standard deviation [SD]) age of 65.8 (11.5) years completed a survey that included questions about basic demographic (...) information, current medical conditions, medications used (prescription and over the counter [OTC]) and the use of oral products to manage SS symptoms. Owing to the self-reporting process in our survey, the term "SS" in our study population represented a mixture of people with SS and people with dry mouth symptoms.The mean (SD) number of daily medications recorded as prescription, OTC and oral care products were 4.9 (3.5), 4.5 (2.8) and 4.6 (1.4), respectively. Participants with four or more comorbid

2014 Journal of the American Dental Association

67. Factors affecting institutionalized older peoples’ self-perceived dry mouth (PubMed)

Factors affecting institutionalized older peoples’ self-perceived dry mouth The purpose of this study was to determine the factors affecting institutionalized older peoples' self-perceived dry mouth.This cross-sectional study was conducted on elderly residents at 22 long-term care facilities. A total of 165 questionnaires were returned from 13 senior citizen welfare institutions (SCWIs) and nine nursing homes. Multiple logistic regression analysis was used to analyze the data obtained.The (...) results showed that the type of long-term care (LTC) facility, regular oral examinations, wearing dentures, and the ability to chew sticky foods affected self-perceived dry mouth. This study determined an association between the type of LTC facility where the participants lived and self-perceived dry mouth.The results indicated the importance of providing oral care in order to improve and prevent dry mouth among institutionalized older people living in SCWIs who do not undergo regular oral

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2014 Quality of Life Research

68. Safety and efficacy of an intra-oral electrostimulator for the relief of dry mouth in patients with chronic graft versus host disease: Case series. (PubMed)

Safety and efficacy of an intra-oral electrostimulator for the relief of dry mouth in patients with chronic graft versus host disease: Case series. Patients with chronic graft-versus-host disease (cGVHD) often suffer from dry mouth and oral mucosal lesions. The primary objective of this study was to investigate the safety of an intra-oral electrostimulator (GenNarino) in symptomatic cGVHD patients. The secondary objective was to study the impact on the salivary gland involvement of cGVHD (...) lesions in areas in contact with the GenNarino during the study. However, only one of them had a change in the National Institutes of Health (NIH) score for oral cGVHD. The unstimulated and stimulated salivary flow rate increased in 4 out of the 5 patients included in this analysis. Symptoms of dry mouth and general oral comfort improved.This study suggests that GenNarino is safe in cGVHD patients with respect to oral tissues. Furthermore the use of GenNarino resulted in subjective and objective

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2014 Medicina oral, patología oral y cirugía bucal

69. The effect of cognitive appraisal for stressors on the oral health-related QOL of dry mouth patients (PubMed)

The effect of cognitive appraisal for stressors on the oral health-related QOL of dry mouth patients Dry mouth is very common symptom, and psychological factors have an influence on this symptom. Although the influence of emotional factor related to patients with oral dryness has been examined in previous studies, the cognitive factors have not been examined thus far.The purpose of this study was to examine the influence of cognitive factors on patients with oral dryness.The participants were

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2014 BioPsychoSocial medicine

70. Chlorhexidine gels and rinses reduce dry socket after third molar extraction

Chlorhexidine gels and rinses reduce dry socket after third molar extraction Chlorhexidine gels and rinses reduce dry socket after third molar extraction - National Elf Service Search National Elf Service Search National Elf Service » » » » Chlorhexidine gels and rinses reduce dry socket after third molar extraction Mar 13 2017 Posted by Dry socket (alveolar osteitis) is a common post-operative complication of permanent tooth extraction. Incidence of alveolar osteitis (AO) has been reported (...) . The primary outcome was incidence of AO and efficacy summaries using risk ratios (RR), preventive fraction and number needed to treat (NNT). Meta-analysis of binary data was conducted using a fixed-effects model. Result s 18 RCTs (16 parallel-group and 2 split-mouth) were included There were 2,824 third molar extractions (1,458 in experimental group and 1,366 in control group). 10 studies involved rinses, 4 using 0.2% concentration others 0.12%. 10 studies used gels, most using 0.2% concentration, 1 using

2017 The Dental Elf

71. Papules, Arthralgia, Dry Mouth and Dry Eyes: A Quiz. (PubMed)

Papules, Arthralgia, Dry Mouth and Dry Eyes: A Quiz. 22367265 2013 05 28 2013 01 10 1651-2057 93 1 2013 Jan Acta dermato-venereologica Acta Derm. Venereol. Papules, arthralgia, dry mouth and dry eyes: a quiz. Diagnosis: Multicentric reticulohistocytosis. 124-5 10.2340/00015555-1327 Jung Hee Dam HD Department of Dermatology, College of Medicine, The Catholic University of Korea 620-56, Jeonnong-dong, Dongdaemun-ku, Seoul, Korea. Kim Hei Sung HS Lee Jun Young JY Kim Hyung Ok HO Park Young Min YM

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2013 Acta Dermato-Venereologica

72. Prospective Assessment of Patient-Reported Dry Eye Syndrome After Whole Brain Radiation. (PubMed)

Prospective Assessment of Patient-Reported Dry Eye Syndrome After Whole Brain Radiation. Dry eye is not typically considered a toxicity of whole brain radiation therapy (WBRT). We analyzed dry eye syndrome as part of a prospective study of patient-reported outcomes after WBRT.Patients receiving WBRT to 25 to 40 Gy were enrolled on a study with dry mouth as the primary endpoint and dry eye syndrome as a secondary endpoint. Patients received 3-dimensional WBRT using opposed lateral fields. Per (...) standard practice, lacrimal glands were not prospectively delineated. Patients completed the Subjective Evaluation of Symptom of Dryness (SESoD, scored 0-4, with higher scores representing worse dry eye symptoms) at baseline, immediately after WBRT (EndRT), and at 1 month (1M), 3 months, and 6 months. Patients with baseline SESoD ≥3 (moderate dry eye) were excluded. The endpoints analyzed were ≥1-point and ≥2-point increase in SESoD score at 1M. Lacrimal glands were retrospectively delineated

2019 Biology and Physics

73. Mouth care

, immunoglobulins and clotting factors help combat invading microbes. The taste buds are stimulated only by substances in solution. Dry foods once mixed with saliva are then able to stimulate the sense of taste ( ). The lips These form a muscular entrance to the mouth. They are covered by squamous, keratinized epithelial tissue, which is vascular and very sensitive. They are necessary for ingestion of food, enunciation of words and are involved in conveying the mood of a person via facial expressions e.g (...) and/or an enlarged or protruding tongue: may be mouth breathers and consequently can experience dry mucosa with an increased risk of mucosal deterioration. Friable mucosa may be experienced by children with epidermolysis bullosa (EB). In addition, dystrophic EB causes severe microstomia which can limit or prevent access to back molar teeth. Restricted movement of the tongue due to surgery or pain may lead to the body’s usual removal of debris being ineffective. Chronic constipation: may cause a foul mouth

2014 Great Ormond Street Hospital

74. Influence of mouth breathing on outcome of scaling and root planing in chronic periodontitis (PubMed)

Influence of mouth breathing on outcome of scaling and root planing in chronic periodontitis Dryness is known to be associated with inflammatory diseases such as dry eye disease and atopic dermatitis. There is significant water loss from the oral cavity during mouth breathing. This study is conducted to estimate the influence of mouth breathing on the outcome of scaling and root planing (SRP) in chronic periodontitis (CP).CP patients comprising of 33 mouth breathers (MBs) and 33 nose breathers (...) group. Sixty-nine percent of BOP positive sites with PD >4 mm were converted into BOP negative sites with PD ≤4 mm in maxillary posterior palatal sites in NB. This success was 38% in MB.Control of periodontal inflammation by SRP in CP patients is affected at palatal sites of mouth breathers.

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2018 BDJ Open

75. Spatial and temporal distribution of foot-and-mouth disease in four districts situated along the Uganda–Tanzania border: Implications for cross-border efforts in disease control (PubMed)

Spatial and temporal distribution of foot-and-mouth disease in four districts situated along the Uganda–Tanzania border: Implications for cross-border efforts in disease control Foot-and-mouth disease (FMD) is one of the major trans-boundary animal diseases in East Africa causing economic loss to farmers and other stakeholders in the livestock industry. Foot-and-mouth disease occurs widely in both Uganda and Tanzania with annual outbreaks recorded. With the recent introduction (...) occurred in 20% of sub-counties and wards immediately neighbouring the Uganda-Tanzania border and 69.5% of the outbreaks occurred during the dry months. While the serotypes of the FMD virus responsible for most outbreaks reported in this region were not known, previous research reported South African Territory (SAT) 1, SAT 2 and O to be the serotypes in circulation. The results from this study provide evidence of the endemic status of FMD on the Uganda-Tanzania border and emphasise that the border area

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2018 The Onderstepoort journal of veterinary research

76. Burning Mouth Syndrome: A Comparative Cross-sectional Study (PubMed)

sensations for at least 6 months without oral clinical signs, and with a normal blood count. Multiple logistic regression analyses were utilized to define the main predictors.Menopause, candidiasis, psychological disorders, job status, denture, and dry mouth were significantly frequent in BMS patients. Multivariate logistic regression indicated age (odds ratio (OR) =1.12, 95% confidence interval (CI): 1.08-1.15, P < 0.0001) and sex (OR = 3.14, 95% CI: 1.4-6.7, P < 0.002) significantly increase the odds (...) Burning Mouth Syndrome: A Comparative Cross-sectional Study Burning mouth syndrome (BMS) may be defined as a burning sensation in the oral mucosa usually unaccompanied by clinical signs. Multiple conditions have been attributed to a burning sensation. The aim of this study was to determine the role of age and sex in BMS.A total of 195 consecutive patients with BMS and 95 healthy patients without burning sensation were recruited in this study. Patients with BMS had experienced oral, burning

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2018 Contemporary clinical dentistry

77. Prerequisites for a dry powder inhaler for children with cystic fibrosis. (PubMed)

Prerequisites for a dry powder inhaler for children with cystic fibrosis. Correct inhalation technique is essential for effective use of dry powder inhalers (DPIs), as their effectiveness largely depends on the patient's inhalation manoeuvre. Children are an especially challenging target population for DPI development due to the large variability in understanding and inspiratory capacities. We previously performed a study in which we determined the prerequisites for a paediatric DPI in a mostly (...) in the mouth during inhalation were recorded with a sinuscope. All children were able to perform a correct inhalation manoeuvre, although video analysis showed that children did not place the inhaler correctly in the mouth in 17% of the cases. No effect was found of medium to high airflow resistance on total inhaled volume, which implies that the whole resistance range tested is suitable for children with CF aged 4-14 years. No effect could be established of either mouthpiece design or airflow resistance

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2017 PLoS ONE

78. Third molar removal: antibiotics reduced risk of dry socket

(18 parallel group, 3 split mouth, 1 two-way crossover) were included. 21 used orally administered antibiotics and one IV administration. Penicillins or nitroimidazoles ( metronidazole,tinidazole) were used. 21 studies (3304 extractions) contributed to the meta-analysis. There were 167 cases of dry socket out of 1479 extractions (11.3%) in the control group and 79 cases of dry socket out of 1825 extractions (4.3%) in the experiment group. There was a statistically significant lower risk of dry (...) Third molar removal: antibiotics reduced risk of dry socket Third molar removal: antibiotics reduced risk of dry socket - National Elf Service Search National Elf Service Search National Elf Service » » » » Third molar removal: antibiotics reduced risk of dry socket Aug 12 2016 Posted by The removal of third molar teeth is a common procedure and dry socket and infection are well-known postoperative problems. Systematic reviews have recommended that the routine use of prophylactic antibiotics

2016 The Dental Elf

79. Hand foot and mouth disease

) or investigate close contacts. Notification is not required in the UK. Contact the local Public Health England (PHE) centre if a large number of children are affected, and an outbreak is suspected. Basis for recommendation Basis for recommendation Advice on hygiene measures Hygiene measures should be encouraged, because spread of hand, foot, and mouth disease is promoted by unwashed virus-contaminated hands, and contact with contaminated surfaces. Droplets containing Coxsackie virus can survive on dry (...) Hand foot and mouth disease Hand foot and mouth disease - NICE CKS Clinical Knowledge Summaries Share Hand foot and mouth disease: Summary Hand, foot, and mouth disease (HFMD) is an acute viral illness characterized by vesicular eruptions in the mouth and papulovesicular lesions of the distal limbs. It should not be confused with foot and mouth disease of animals, which is caused by a different virus. HFMD is usually mild and self-limiting. It is most commonly due to Coxsackie A16 virus

2016 NICE Clinical Knowledge Summaries

80. Effect of Resveratrol Dry Suspension on Immune Function of Piglets. (PubMed)

Effect of Resveratrol Dry Suspension on Immune Function of Piglets. Resveratrol, a polyphenolic plant antitoxin, has a wide range of pharmacological activities. In this study, we systematically evaluated the effects of resveratrol dry suspension (RDS) on immune function in piglets that were treated with different doses of RDS for 2 weeks. The results showed that the RDS has significant effects on the development, maturation, proliferation, and transformation of T lymphocytes. RDS could regulate (...) humoral immune responses by upregulating the release of IFN-γ and downregulating the release of TNF-α. After piglets were vaccinated against classical swine fever virus and foot-and-mouth disease virus, the antibody titers were significantly increased. RDS treatment showed an excellent resistance to enhance T-SOD activity. Values of blood routine and blood biochemistry showed no toxicity. These results suggested that RDS could be considered as an adjuvant to enhance immune responses to vaccines

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2018 Evidence-based Complementary and Alternative Medicine (eCAM)

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