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61. Oral Thrush - Guidelines for Prescribing Oral Nystatin

of age unless related to antibiotic use, immunosuppression or steroid inhaler use without post-use mouth rinsing. Risk factors: Medical conditions: Immunosuppression Malignancy Sjogren's disease Diabetes Cushings disease Medications: Inhaled corticosteroids (if not rinsing mouth properly) Recent broad-spectrum antibiotic use Chemotherapy or radiation therapy Age (newborns, or over 65) Pregnancy Dentures Poor oral hygiene Chronic dry mouth For photos and more information go to : Three types of oral (...) Oral Thrush - Guidelines for Prescribing Oral Nystatin Oral Thrush - Guidelines for Prescribing Oral Nystatin - medSask Home - College of Pharmacy and Nutrition - University of Saskatchewan Toggle Menu Search the U of S Search Oral Thrush - Guidelines for Prescribing Oral Nystatin Oral thrush is a fungal infection of the oral mucosa caused by Candida species. It is the most common human fungal infection. Oral thrush may refer to candidiasis in the mouths of babies, or if occurring in the mouth

2017 medSask

62. Oral mucosal manifestations in primary and secondary Sjögren syndrome and dry mouth syndrome Full Text available with Trip Pro

Oral mucosal manifestations in primary and secondary Sjögren syndrome and dry mouth syndrome One of the most important symptoms of Sjögren syndrome is xerostomia. The oral cavity deprived of saliva and its natural lubricative, protective and antibacterial properties is prone to a number of unfavourable consequences.To present the most important lesions on the oral mucosa in primary and secondary Sjögren syndrome and in dry mouth syndrome.The study group comprised 55 patients including 52 women (...) and 3 men aged 20-72 years (average: 28.25 years).Basing on the accepted criteria, primary Sjögren syndrome was diagnosed in 22 (40%) patients, secondary Sjögren syndrome in 18 (32.7%) patients, and dry mouth syndrome in 15 (27.27%) patients. The physical examination and the examination of the mouth were performed and history was elicited from every patient.The most common pathologies appearing on the oral mucosa in primary and secondary Sjögren syndrome are angular cheilitis, cheilitis, increased

2016 Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii

63. n-3 Fatty Acid Supplementation for the Treatment of Dry Eye Disease. Full Text available with Trip Pro

n-3 Fatty Acid Supplementation for the Treatment of Dry Eye Disease. Dry eye disease is a common chronic condition that is characterized by ocular discomfort and visual disturbances that decrease quality of life. Many clinicians recommend the use of supplements of n-3 fatty acids (often called omega-3 fatty acids) to relieve symptoms.In a multicenter, double-blind clinical trial, we randomly assigned patients with moderate-to-severe dry eye disease to receive a daily oral dose of 3000 mg (...) in the conjunctival staining score (mean difference in change, 0.0 points; 95% CI, -0.2 to 0.1), corneal staining score (0.1 point; 95% CI, -0.2 to 0.4), tear break-up time (0.2 seconds; 95% CI, -0.1 to 0.5), and result on Schirmer's test (0.0 mm; 95% CI, -0.8 to 0.9). At 12 months, the rate of adherence to treatment in the active supplement group was 85.2%, according to the level of n-3 fatty acids in red cells. Rates of adverse events were similar in the two trial groups.Among patients with dry eye disease

2018 NEJM Controlled trial quality: predicted high

64. Relative Bioavailability Study in Healthy Subjects Comparing 2 Dry Powder Oral Suspensions of Rivaroxaban Under Fasting and 20 mg of an Oral Suspension of Rivaroxaban Under Fed Conditions to 10 mg of an Immediate Release Tablet Under Fasting Conditions

Relative Bioavailability Study in Healthy Subjects Comparing 2 Dry Powder Oral Suspensions of Rivaroxaban Under Fasting and 20 mg of an Oral Suspension of Rivaroxaban Under Fed Conditions to 10 mg of an Immediate Release Tablet Under Fasting Conditions Relative Bioavailability Study in Healthy Subjects Comparing 2 Dry Powder Oral Suspensions of Rivaroxaban Under Fasting and 20 mg of an Oral Suspension of Rivaroxaban Under Fed Conditions to 10 mg of an Immediate Release Tablet Under Fasting (...) Conditions - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Relative Bioavailability Study in Healthy Subjects Comparing 2 Dry Powder Oral Suspensions of Rivaroxaban Under Fasting and 20 mg of an Oral Suspension

2015 Clinical Trials

65. To Evaluate the Bioavailability of a Single Oral Dose of the Acetylsalicylic Acid Containing Dry Powder 500 mg in Comparison to the Bioavailability of a Single Oral Dose of Aspirin Tablets and Aspirin Effervescent Tablets in Healthy Adults.

To Evaluate the Bioavailability of a Single Oral Dose of the Acetylsalicylic Acid Containing Dry Powder 500 mg in Comparison to the Bioavailability of a Single Oral Dose of Aspirin Tablets and Aspirin Effervescent Tablets in Healthy Adults. To Evaluate the Bioavailability of a Single Oral Dose of the Acetylsalicylic Acid Containing Dry Powder 500 mg in Comparison to the Bioavailability of a Single Oral Dose of Aspirin Tablets and Aspirin Effervescent Tablets in Healthy Adults. - Full Text View (...) - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. To Evaluate the Bioavailability of a Single Oral Dose of the Acetylsalicylic Acid Containing Dry Powder 500 mg in Comparison to the Bioavailability of a Single Oral Dose of Aspirin Tablets

2015 Clinical Trials

66. Oral isotretinoin for acne. Full Text available with Trip Pro

on very low-quality evidence.Isotretinoin may slightly improve (by 15%) acne severity, assessed by physician's global evaluation (RR 1.15, 95% CI 1.00 to 1.32; 351 participants; 2 studies), but resulted in more less serious adverse effects (67% higher risk) (RR 1.67, 95% CI 1.42 to 1.98; 351 participants; 2 studies), such as dry lips/skin, cheilitis, vomiting, nausea (both outcomes, low-quality evidence).Different doses/therapeutic regimens of oral isotretinoinFor our primary efficacy outcome, we (...) Oral isotretinoin for acne. Acne vulgaris, a chronic inflammatory disease of the pilosebaceous unit associated with socialisation and mental health problems, may affect more than 80% of teenagers. Isotretinoin is the only drug that targets all primary causal factors of acne; however, it may cause adverse effects.To assess efficacy and safety of oral isotretinoin for acne vulgaris.We searched the following databases up to July 2017: the Cochrane Skin Group Specialised Register, CENTRAL, MEDLINE

2018 Cochrane

67. Severe sialorrhoea (drooling) in children and young people with chronic neurological disorders: oral glycopyrronium bromide

neurological disorders: oral glycopyrronium bromide (ES5) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 34Safety Safety The SPC states that adverse effects are common with glycopyrronium bromide due to its anticholinergic action. The most common adverse reactions include dry mouth, constipation, diarrhoea, vomiting, urinary retention, flushing and nasal congestion. The SPC advises that anticholinergic adverse (...) %) Patients reporting any adverse event 20/20 (23%) 15/18 (83%) Not reported Severe sialorrhoea (drooling) in children and young people with chronic neurological disorders: oral glycopyrronium bromide (ES5) © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 26 of 34Patients reporting an adverse event considered to be treatment-related 15/20 (75%) 7/18 (39%) Dry mouth 8/20 (40%) 2/18 (11%) Constipation 6/20 (30%) 4/18 (22

2017 National Institute for Health and Clinical Excellence - Advice

68. Prevention of Dry Socket After Tooth Extraction With Warm Saline Rinses

Prevention of Dry Socket After Tooth Extraction With Warm Saline Rinses UTCAT2996, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Prevention of Dry Socket After Tooth Extraction With Warm Saline Rinses Clinical Question Is warm saline rinse beneficial in preventing alveolar osteitis after dental extraction? Clinical Bottom Line Warm saline mouth rinses 24 hours after dental extraction is helpful in reducing (...) for post extraction complication. Applicability Rinsing with warm salt water after 24 hours is helpful in preventing post extraction complication such as alveolar osteitis. Warm saline rinsing twice a day is easy to follow by the patient and is a low cost rinse. It appears that rinsing two times a day is as beneficial as rinsing six times a day in the prevention of alveolar osteitis. Specialty/Discipline (General Dentistry) (Oral Surgery) Keywords Dental extraction complications, Dry socket, alveolar

2016 UTHSCSA Dental School CAT Library

69. Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis. Full Text available with Trip Pro

the efficacy of an inhaled dry powder combination, referred to as Pyrazinoic acid/ester Dry Powder (PDP), which is comprised of pyrazinoic acid (POA), the active moiety of PZA, and pyrazinoic acid ester (PAE), which is a PZA analog. Both POA and PAE have the advantage of being able to act on PZA-resistant Mycobacterium tuberculosis. When used in combination with oral rifampicin (R), inhaled PDP had striking effects on tissue pathology. Effects were observed in lungs, the site of delivery, but also (...) Efficacy of pyrazinoic acid dry powder aerosols in resolving necrotic and non-necrotic granulomas in a guinea pig model of tuberculosis. New therapeutic strategies are needed to treat drug resistant tuberculosis (TB) and to improve treatment for drug sensitive TB. Pyrazinamide (PZA) is a critical component of current first-line TB therapy. However, the rise in PZA-resistant TB cases jeopardizes the future utility of PZA. To address this problem, we used the guinea pig model of TB and tested

2018 PLoS ONE

70. Development and evaluation of Chitosan nanoparticles based dry powder inhalation formulations of Prothionamide. Full Text available with Trip Pro

Development and evaluation of Chitosan nanoparticles based dry powder inhalation formulations of Prothionamide. Prothionamide (PTH), a second line antitubercular drug is used to administer in conventional oral route. However, its unpredictable absorption and frequent administration limit its use. An alternate approach was thought of administering PTH through pulmonary route in a form of nanoparticles, which can sustain the release for several hours in lungs. Chitosan, a bio-degradable polymer (...) was used to coat PTH and further freeze dried to prepare dry powder inhaler (DPI) with aerodynamic particle size of 1.76μm. In vitro release study showed initial burst release followed by sustained release up to 96.91% in 24h. In vitro release further correlated with in vivo study. Prepared DPI maintained the PTH concentration above MIC for more than 12h after single dose administration and increased the PTH residency in the lungs tissue more than 24h. Animal study also revealed the reduction of dose

2018 PLoS ONE

71. The impact of poor oral health on the oral health-related quality of life (OHRQoL) in older adults: the oral health status through a latent class analysis. Full Text available with Trip Pro

(GOHAI). Clinical evaluation of their oral health: painful chewing, use of dentures, dry mouth, xerostomia, plaque, calculus, coronal and root caries, tooth loss and gingival bleeding. Finally, we determined the oral health of participants through Latent Class Analysis (LCA), excluding totally edentulous. The strength of association was determined (Odds Ratio [OR] and 95% confidence interval [95% CI]) through logical regression between the oral health categories (latent classes) and OHRoL in older (...) The impact of poor oral health on the oral health-related quality of life (OHRQoL) in older adults: the oral health status through a latent class analysis. Determine the impact of poor oral health on the oral health-related quality of life (OHRQoL) in community-dwelling older adults.Cross-sectional study of community-dwelling older adults in Mexico City. Sociodemographic characteristics were obtained and assessed their OHRQoL according to the Geriatric/General Oral Health Assessment Index

2019 BMC Oral Health

72. Mouth Care

complications. Key principles Assess every patient Plan regular effective mouth care Confidence to refer Identify urgent referrals. Assessment All patients are at risk of oral problems and will benefit from planned regular mouth care, particularly patients receiving chemotherapy or radiotherapy who will need careful monitoring both pre- and post-treatment. Drug history is significant as numerous medications can affect the oral environment: opioids, diuretics and anticholinergics increase dry mouth steroids (...) increase the risk of candidosis bisphosphonates increase the risk of osteonecrosis of the jaw. Ill-fitting dentures and surgical intervention including tooth extraction increase this risk, highlighting the need for preventative oral hygiene therapy. Ask patients on a daily basis if they are having problems Ensure privacy Remove dentures before examining the mouth or performing routine mouth care Use a torch to thoroughly examine the mouth Check the lining of the mouth is clean. If not, refer to dry

2018 Scottish Palliative Care Guidelines

73. Restoration Materials in Dry Mouth Patients

Restoration Materials in Dry Mouth Patients UTCAT789, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Restoration Materials In Dry Mouth Patients Clinical Question For a patient with dry mouth, which restorative material, amalgam or resin composite, has the lowest incidence of recurrent caries? Clinical Bottom Line Glass ionomer has the lowest incidence of recurrent caries when compared to amalgam. (See Comments (...) the success of resin restorations are compared to amalgam restorations in xerostomic patients. No potential harm to the patient. Patient benefit is the placement of the most successful restorative material. Specialty/Discipline (General Dentistry) (Restorative Dentistry) Keywords Dry mouth, xerostomia, amalgam, resin composite, caries ID# 789 Date of submission: 04/14/2011 E-mail garciam30@livemail.uthscsa.edu Author Meagan D. Garcia Co-author(s) Co-author(s) e-mail Faculty mentor/Co-author Vidya Sankar

2011 UTHSCSA Dental School CAT Library

74. Prospective Assessment of Patient-Reported Dry Eye Syndrome After Whole Brain Radiation. (Abstract)

Prospective Assessment of Patient-Reported Dry Eye Syndrome After Whole Brain Radiation. Dry eye is not typically considered a toxicity of whole brain radiation therapy (WBRT). We analyzed dry eye syndrome as part of a prospective study of patient-reported outcomes after WBRT.Patients receiving WBRT to 25 to 40 Gy were enrolled on a study with dry mouth as the primary endpoint and dry eye syndrome as a secondary endpoint. Patients received 3-dimensional WBRT using opposed lateral fields. Per (...) standard practice, lacrimal glands were not prospectively delineated. Patients completed the Subjective Evaluation of Symptom of Dryness (SESoD, scored 0-4, with higher scores representing worse dry eye symptoms) at baseline, immediately after WBRT (EndRT), and at 1 month (1M), 3 months, and 6 months. Patients with baseline SESoD ≥3 (moderate dry eye) were excluded. The endpoints analyzed were ≥1-point and ≥2-point increase in SESoD score at 1M. Lacrimal glands were retrospectively delineated

2019 Biology and Physics

75. The comparison of fennel infusion plus dry cupping versus metformin in management of oligomenorrhoea in patients with polycystic ovary syndrome: a randomised clinical trial. (Abstract)

. The mean pain severity dropped significantly in Group A. Fennel seed infusion plus a dry cupping uses a safe and effective therapeutic intervention in the management of oligomenorrhoea. IMPACT STATEMENT What is already known on this subject? Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women. Some common clinical manifestations of this syndrome include menstrual disorders such as oligomenorrhoea and amenorrhoea. The recommended therapeutic interventions include oral intervention (...) The comparison of fennel infusion plus dry cupping versus metformin in management of oligomenorrhoea in patients with polycystic ovary syndrome: a randomised clinical trial. Oligomenorrhoea treatment with hormone therapy and Metformin is not usually well tolerated and is associated with a broad range of side effects. In Persian medicine, the management of oligomenorrhoea can be done with fennel and dry cupping. A clinical trial was conducted on 61 patients with oligomenorrhoea. The patients

2019 Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology Controlled trial quality: uncertain

76. Real-life effectiveness of inhaler device switch from dry powder inhalers to pressurized metred-dose inhalers in patients with asthma treated with ICS/LABA. Full Text available with Trip Pro

Real-life effectiveness of inhaler device switch from dry powder inhalers to pressurized metred-dose inhalers in patients with asthma treated with ICS/LABA. Mixed inhaler device use for asthma is associated with worse inhaler technique and outcomes. Given that relievers are commonly prescribed as pressurized metred-dose inhalers (pMDI), changing preventers from dry powder inhalers (DPI) to pMDI may improve asthma outcomes. This study aimed to assess the persistence and effectiveness (...) respiratory diagnosis or acute course of oral corticosteroids) and overall asthma control (OAC; RDAC and ≤ 200 μg salbutamol/≤500 μg terbutaline average daily dose) comparing 1 year after and before the switch.Within 85 patients who switched from DPI to pMDI and persisted for a year, higher proportion were free from asthma exacerbation after the switch (mean difference in proportion = 0.129, 95% CI: 0.038-0.220). Switching to pMDI was also associated with better RDAC (75.3% vs 57.7%, P = 0.001) and OAC

2019 Respirology

77. Meibomian Gland Dysfunction and Dry Eye are Similar, but Different based on a Population-Based Study (Hirado-Takushima Study) in Japan. Full Text available with Trip Pro

Meibomian Gland Dysfunction and Dry Eye are Similar, but Different based on a Population-Based Study (Hirado-Takushima Study) in Japan. To evaluate the prevalence and risk factors of and the relation between meibomian gland dysfunction (MGD) and dry eye (DE) in Japan.A population-based cross-sectional study.Participants filled in questionnaires regarding ocular symptoms, systemic diseases, and lifestyle factors. Meibomian gland-related parameters and tear film-related parameters were evaluated (...) was 32.9% and 33.4%, respectively, with a coexistence rate of 12.9%. The prevalence of MGD was associated with male sex (odds ratio [OR], 2.42), age (OR per decade increment,1.53), and oral intake of lipid-lowering agents (OR, 3.22). The prevalence of DE was associated with female sex (OR, 3.36), contact lens wear (OR, 2.84), conjunctivochalasis (OR, 2.57) and lid margin abnormalities (OR, 3.16). The age-specific prevalence of MGD and DE differed, and factor analysis for 16 parameters showed that MGD

2019 American Journal of Ophthalmology

78. Comparison of the Efficacies of Dry Needling and Botox Methods in the Treatment of Myofascial Pain Syndrome Affecting the Temporomandibular Joint. (Abstract)

Comparison of the Efficacies of Dry Needling and Botox Methods in the Treatment of Myofascial Pain Syndrome Affecting the Temporomandibular Joint. To compare the efficacies of botulinum toxin-A injection and dry needling methods in the treatment of patients with myofascial pain syndrome (MPS) in the temporomandibular joint (TMJ).In this prospective study, 40 MPS patients (29 women, 11 men) were randomly assigned to abobotulinum toxin-A injection (Group 1, n = 20) or dry needling (Group 2, n (...)  = 20) groups. Pain, crepitation, functional limitation, maximum mouth opening, jaw strength were evaluated at baseline and 6 weeks, and the results in both groups were compared.The average age of the authors' patients was 33.8±8.1. There was a remarkable difference between 2 groups regarding visual analog scale for TMJ pain at rest (P = 0.048). The pain at rest was relieved more effectively in Group 2 at the end of 6 weeks. Improvement in jaw protrusion angles on the right (P = 0.009) and left (P

2019 The Journal of craniofacial surgery Controlled trial quality: uncertain

79. Preliminary Report on the Role of Dry Needling Versus Corticosteroid Injection, an Effective Treatment Method for Plantar Fasciitis: A Randomized Controlled Trial. (Abstract)

Preliminary Report on the Role of Dry Needling Versus Corticosteroid Injection, an Effective Treatment Method for Plantar Fasciitis: A Randomized Controlled Trial. Plantar fasciopathy (PF) is a common disorder for which there is no consensus regarding an optimal treatment strategy. We hypothesized that dry needling would be as effective as the use of corticosteroid injections for treating PF while avoiding the potential adverse effects of corticosteroids. After approval was received from (...) the institutional review board, patients diagnosed with PF were prescribed a 3-week nonoperative treatment regimen. In addition to using oral and topical antiinflammatory drugs, patients engaged in plantar fascia and gastrocnemius stretching exercises. A study population of 98 patients was planned. An appointment was made in the third week of first-line treatment. Patients whose pain did not abate and who required further treatment were included in the study. One week later, we randomly divided patients into 2

2019 The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons Controlled trial quality: uncertain

80. Pregabalin Failed to Prevent Dry Eye Symptoms after Laser-Assisted in Situ Keratomileusis (LASIK) in a Randomized Pilot Study. Full Text available with Trip Pro

after laser-assisted in situ keratomileusis (LASIK).Prospective, masked, randomized single-center pilot study. Patients were treated with either pregabalin (oral solution of pregabalin 150 mg twice daily, first dose prior to surgery, continued for a total of 28 doses over 14 days) or placebo solution. The primary outcome was dry eye symptoms as measured by the Dry Eye Questionnaire 5 (DEQ-5). Secondary outcome measures included pain-related eye symptoms.In total, 43 individuals were enrolled (...) Pregabalin Failed to Prevent Dry Eye Symptoms after Laser-Assisted in Situ Keratomileusis (LASIK) in a Randomized Pilot Study. Perioperative pregabalin administration has been found to reduce the risk of persistent pain after a variety of surgical procedures. However, this approach has not been tested in relation to eye surgery. As such, the purpose of this study was to evaluate whether perioperative pregabalin can reduce the presence of dry eye (DE) symptoms, including eye pain, six months

2019 Journal of clinical medicine Controlled trial quality: uncertain

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