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Dry Mouth

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41. Effects of A Novel Disc Formulation on Dry Mouth Symptoms and Enamel Remineralization in Patients With Hyposalivation: An In Vivo Study Full Text available with Trip Pro

Effects of A Novel Disc Formulation on Dry Mouth Symptoms and Enamel Remineralization in Patients With Hyposalivation: An In Vivo Study The goal of this study was to identify the in vivo effects in patients with hyposalivation of a novel slowly dissolving adhering test disc upon on enamel remineralization, oral biofilm, salivary production, pH and buffering, gingival health, and on self-evaluation of oral well-being.Five subjects with xerostomia wore custom made retainers carrying 5 (...) >0.05). The discs favorably impacted eating problems and dental sensitivity. Subjects were positive about disc flavor and mouth feel.Using established in vivo techniques, the effects of a novel product in xerostomic patients were evaluated and quantified. The adhering disc facilitated eating, reduced dental sensitivity, improved saliva production and buffering capacity, reduced plaque, and alleviated xerostomia symptoms.Xerostomia management is challenging. A novel dry mouth disc was effective

2017 Dentistry (Sunnyvale, Calif.) Controlled trial quality: uncertain

42. Whey protein mouth drying influenced by thermal denaturation Full Text available with Trip Pro

Whey protein mouth drying influenced by thermal denaturation Whey proteins are becoming an increasingly popular functional food ingredient. There are, however, sensory properties associated with whey protein beverages that may hinder the consumption of quantities sufficient to gain the desired nutritional benefits. One such property is mouth drying. The influence of protein structure on the mouthfeel properties of milk proteins has been previously reported. This paper investigates the effect (...) increased with longer heating times. As the pH of all samples was close to neutral, this implies that neither the precipitation of whey proteins at low pH, nor their acidity, as reported in previous literature, can be the drying mechanisms in this case. The increase in mouth drying with increased heating time suggests that protein denaturation is a contributing factor and a possible mucoadhesive mechanism is discussed.

2017 Food quality and preference

43. The Cause of Dry Mouth During CPAP Application Full Text available with Trip Pro

The Cause of Dry Mouth During CPAP Application 28162149 2018 12 28 1550-9397 13 4 2017 04 15 Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine J Clin Sleep Med The Cause of Dry Mouth During CPAP Application. 647 10.5664/jcsm.6568 Bortolotti Mauro M Department of Gastroenterology and Internal Medicine, S.Orsola-Malpighi Polyclinic, University of Bologna, Italy. eng Letter 2017 04 15 United States J Clin Sleep Med 101231977 1550-9389 2016

2017 Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

44. Evaluation of a novel dry eye model induced by oral administration of finasteride Full Text available with Trip Pro

Evaluation of a novel dry eye model induced by oral administration of finasteride Dry eye is a common eye disease, and suitable animal models are indispensable for investigating the pathogenesis and developing treatments for dry eye. The present study was conducted to develop an androgen deficiency dry eye model induced by finasteride, and to evaluate ocular surface status and inflammatory cytokine gene expression in the lacrimal gland using a cytokine antibody array system. The results (...) revealed that the antiandrogenic drug finasteride induced significant tear deficiency, and the histopathology results revealed significant inflammatory cell infiltration in the lacrimal gland. The cytokine antibody array system identified increased B7‑2 (also known as cluster of differentiation 86), interleukin (IL)‑1β, IL‑4, IL‑6, IL‑10, matrix metalloproteinase‑8, Fas ligand, tumor necrosis factor (TNF)‑α and metalloproteinase inhibitor 1 levels in the lacrimal gland of the dry eye model

2017 Molecular medicine reports

45. Aloe vera for Dry Mouth Denture Patients – Palliative Therapy Full Text available with Trip Pro

Aloe vera for Dry Mouth Denture Patients – Palliative Therapy Xerostomia (dry mouth) is dryness of the mouth which is due to reduced salivary flow. Lack of adequate saliva causes discomfort in denture wearing patients and decreases retention of dentures. The ability of saliva to wet the tissue surface is one of the most important properties for oral comfort and retention of complete denture in dry mouth patients.This study was conducted to evaluate and compare the wetting ability

2017 Journal of clinical and diagnostic research : JCDR

46. Evaluation of wetting ability of five new saliva substitutes on heat-polymerized acrylic resin for retention of complete dentures in dry mouth patients: a comparative study Full Text available with Trip Pro

Evaluation of wetting ability of five new saliva substitutes on heat-polymerized acrylic resin for retention of complete dentures in dry mouth patients: a comparative study The aim of this study was to evaluate & compare the wetting ability of five saliva substitutes & distilled water on heat-polymerized acrylic resin. Contact angle of the saliva substitute on denture base can be taken as an indicator of wettability. Good wetting of heat-polymerized acrylic resin is critical for optimum (...) ), and Moi-Stir (Group VI).The contact angles of five saliva substitutes and distilled water were measured and compared. Group II (AQWET) has the lowest advancing and receding contact angle values and the highest angle of hysteresis on heat-polymerized acrylic resin. Based on contact angle values, Group II (AQWET) has the best wetting ability on heat-cured acrylic resins. The ability of saliva to wet the denture surface is one of the most important properties for complete denture retention in dry mouth

2017 The Pan African medical journal

47. Restoration of Tear Secretion in a Murine Dry Eye Model by Oral Administration of Palmitoleic Acid Full Text available with Trip Pro

Restoration of Tear Secretion in a Murine Dry Eye Model by Oral Administration of Palmitoleic Acid Sea buckthorn (Hippophae rhamnoides)-derived products have traditionally been used as food and medicinal ingredients in Eastern countries. The purpose of this study was to investigate the effect of oral intake of sea buckthorn oil products on tear secretion using a murine dry eye model. Orally administered sea buckthorn pulp oil (not seed oil) restored aqueous tear secretion to its normal value (...) under a dry eye condition. Palmitoleate (C16:1), a fatty acid present in sea buckthorn pulp oil, preserved tear secretion and suppressed inflammatory cytokines in the lacrimal gland to the same extent as that by pulp oil. These results suggest that an oral intake of sea buckthorn pulp oil has a potency to preserve tear secretion capacity in the dry eye state and palmitoleate, its main constituent fatty acid, is an active component of the oil. This effect may enable a potent diet-based treatment

2017 Nutrients

48. "Hyaluronan" Formulation for Type 2 Diabetic Patients With Dry Mouth

-over group, randomized, single center, study will evaluate the efficacy of HA formulation in alleviating dry mouth in type 2 diabetic patients. Condition or disease Intervention/treatment Phase Dry Mouth Xerostomia Type 2 Diabetics Device: HA formulation Oral Spray Device: Placebo Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 30 participants Allocation: Randomized Intervention Model: Crossover Assignment (...) and schedule of the study. Exclusion Criteria: Subjects with open mouth sores at study entry. Any pathology that, based on the judgement of the researcher, could negatively affect the oral mucosa and subsequent treatment for xerostomia. Subjects who are nursing, becoming pregnant or plan to become pregnant during the study period Subjects currently on medication or treatment for dry mouth/xerostomia Hypersensitivity to any of the following ingredients- HA ,xylitol and Sodium Benzoate. Subjects with soft

2017 Clinical Trials

49. Effect of an Oral Supplement Containing Omega-3 and Omega-6 on Dry Eye Symptoms

Effect of an Oral Supplement Containing Omega-3 and Omega-6 on Dry Eye Symptoms Effect of an Oral Supplement Containing Omega-3 and Omega-6 on Dry Eye Symptoms - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Effect of an Oral Supplement Containing Omega-3 and Omega-6 on Dry Eye Symptoms (TURMERIC) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03265327 Recruitment Status : Completed First Posted : August 29, 2017 Last Update Posted : August 23, 2018 Sponsor: Nature's Way Canada Collaborator: Centre

2017 Clinical Trials

50. "Hyaluronan" Formulation for Dry Mouth in Sleep Apnea Patients

/treatment Phase Dry Mouth Xerostomia OSA Sleep Apnea Device: Test Oral Spray Device: Placebo Oral Spray Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 45 participants Allocation: Randomized Intervention Model: Crossover Assignment Masking: Triple (Participant, Care Provider, Investigator) Primary Purpose: Treatment Official Title: Clinical Evaluation of the Efficacy of "Hyaluronan" Formulation for Dry Mouth (...) the assigned mouth spray provided for the 4 week duration of the study. Device: Test Oral Spray HA formulation of FDA listed ingredients Placebo Comparator: Placebo Oral Spray Subjects will be instructed to mouth spray with 0.3 ml ( 2 sprays to the mouth) of their placebo mouth spray, 2 times daily (morning and evening), for the 4 week duration of the study. Device: Placebo Oral Spray Placebo formulation without the active ingredients Outcome Measures Go to Primary Outcome Measures : Relief from dry mouth

2017 Clinical Trials

51. Subjective Assessment of Enamelon® Preventive Treatment Gel in a Self-Reported Dry-Mouth Population. (Abstract)

Subjective Assessment of Enamelon® Preventive Treatment Gel in a Self-Reported Dry-Mouth Population. The efficacy of stannous fluoride toothpastes is well established for reducing caries, plaque, and gingivitis and relieving the discomfort of dentin hypersensitivity. Management of dry mouth may include relief remedies in addition to usual oral hygiene methods to maintain oral health and improve quality of life. This 6-week, single-blind, randomized, two-period crossover clinical study (...) was designed to evaluate the oral tolerance and potential of Enamelon® Preventive Treatment Gel (EPTG), with 0.4% stannous fluoride, to relieve subject-perceived dry-mouth symptoms in a self-reported dry-mouth population, after 14 days of use, compared to a marketed over-the-counter (OTC) artificial saliva gel product (Biotene® Oral Balance Gel [BOBG]).Following a 7-day washout period, 52 qualified subjects with self-reported dry-mouth symptoms received EPTG or BOBG for once-daily use for 14 days. All

2017 Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995) Controlled trial quality: uncertain

52. The Null Effect of Chewing Gum During Hemodialysis on Dry Mouth. (Abstract)

The Null Effect of Chewing Gum During Hemodialysis on Dry Mouth. The study was conducted to determine the effect of chewing gum during hemodialysis on dry mouth and its symptoms.The imposition of fluid restriction and the use of medications that reduce saliva production may lead to dry mouth.This study is a randomized, controlled, single-blind, crossover experimental study.The subjects consisted of 61 hemodialysis patients recruited from 4 dialysis centers in southern Turkey. The data were (...) collected using a Patient Identification Form, a Form for Assessing the Symptoms of Dry Mouth, and a Patient Follow-up Form. Saliva samples were obtained for analysis of flow rates.The salivary flow rates of the patients increased during the first hour on the day when gum was chewed, and this increase was statistically significant. However, no significant difference was found between the salivary flow rates at the 0- and 4-hour time points on the day when gum was chewed (P > .05). In addition

2017 Clinical nurse specialist CNS Controlled trial quality: uncertain

53. Effectiveness of an Intervention Bundle on Thirst Intensity and Dry Mouth Among Patients in ICUs

information Ages Eligible for Study: 18 Years to 75 Years (Adult, Older Adult) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: 18 or above 18 years of age. Having thirst score ≥ 5 and dry mouth score ≥ 1 Willing to participate in the study. Able to report verbally or non verbally about thirst intensity. Admitted in ICCU,Respiratory ICU, Neurosurgical ICU and step Up ICU Exclusion Criteria: On mechanical ventilation. Not able to follow the commands. Having any oral (...) Effectiveness of an Intervention Bundle on Thirst Intensity and Dry Mouth Among Patients in ICUs Effectiveness of an Intervention Bundle on Thirst Intensity and Dry Mouth Among Patients in ICUs - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2017 Clinical Trials

54. Oral Omega-3 Fatty Acid Supplementation for Laser In Situ Keratomileusis-Associated Dry Eye. (Abstract)

Oral Omega-3 Fatty Acid Supplementation for Laser In Situ Keratomileusis-Associated Dry Eye. To determine the effect of oral omega-3 fatty acid (ω3FA) supplementation in laser in situ keratomileusis (LASIK)-associated dry eye.In this prospective, open-label study, patients undergoing LASIK were randomized to receive either 1.2 g/d of a triglyceride formulation of oral ω3FA (treatment group) or 400 mg/d vitamin E (control group) for 1 week before and continued for 12 weeks after surgery. Ocular

2017 Cornea Controlled trial quality: uncertain

55. Effects of oral intake of heat-killed Lactobacillus brevis SBC8803 (SBL88™) on dry skin conditions: A randomized, double-blind, placebo-controlled study. Full Text available with Trip Pro

Effects of oral intake of heat-killed Lactobacillus brevis SBC8803 (SBL88™) on dry skin conditions: A randomized, double-blind, placebo-controlled study. Lactobacilli are important in intestinal homeostasis, which involves the regulation of immune function, digestive health, cholesterol absorption and intestinal tumor growth amongst others. Our previous investigations have suggested that oral intake of heat-killed Lactobacillus brevis (L. brevis) SBC8803 (SBL88™) suppresses dermatitis (...) frequency of taking lactic fermentation products was less than once per week, the levels of corneal hydration at the neck (in the 50 mg/day group) and lower eye region (in the 25 mg/day group) were significantly increased at week 12 (P<0.05). In conclusion, the results of the present investigation suggest that oral intake of heat-killed L. brevis SBC8803 is effective at improving skin hydration conditions in populations with low habitual frequency of taking lactic fermentation products.

2017 Experimental and therapeutic medicine Controlled trial quality: uncertain

56. Fish oil supplements are ineffective for treating dry eyes

that omega-3 fatty acid products may be beneficial in the treatment of dry eye. Although they say evidence is insufficient to support the effectiveness of any particular formulation. Similarly, UK guidelines from the College of Optometrists (2018) recommend a diet rich in omega-3 essential fatty acids for patients with dry eyes. A weak recommendation for oral essential fatty acid ‘fish oil’ supplements is also given, though the absence of high-quality trials to inform practice is noted. What (...) for oral essential fatty acid ‘fish oil’ supplements is also given, though the absence of high-quality trials to inform practice is noted. What are the implications? Using a representative group of patients, multiple outcome measures, and one-year follow up, this randomised controlled trial provides strong evidence that fish oil supplements are no more effective than placebo for the treatment of dry eyes. This is high-quality evidence that resolves the uncertainty surrounding the use of this treatment

2019 NIHR Dissemination Centre

57. A randomized clinical trial in subjects with dry mouth evaluating subjective perceptions of an experimental oral gel, an oral rinse and a mouth spray compared to water. (Abstract)

A randomized clinical trial in subjects with dry mouth evaluating subjective perceptions of an experimental oral gel, an oral rinse and a mouth spray compared to water. This multicenter, randomized, parallel group study analyzed the effectiveness of an experimental oral gel, a commercially available oral rinse and a commercially available mouth spray versus water alone at relieving self-reported symptoms of dry mouth over a 28-day home use treatment period. The effects of the study treatments (...) on dry mouth-related quality of life (QoL) were also investigated.Eligible subjects were stratified by dry mouth severity (mild, moderate or severe) and randomized to receive one of the study treatments. Prior to first use they completed a questionnaire designed to assess their baseline dry mouth-related QoL. Following first use and on Day 8 (2 hours post-treatment only) and Day 29, subjects completed the modified Product Performance and Attributes Questionnaire (PPAQ) I at 0.5, 1, 2 and 4 hours post

2016 American journal of dentistry Controlled trial quality: uncertain

58. Medication Causes of Dry Mouth

Medication Causes of Dry Mouth Medication Causes of Dry Mouth Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Medication Causes of Dry (...) Mouth Medication Causes of Dry Mouth Aka: Medication Causes of Dry Mouth , Medication Causes of Dry Eyes From Related Chapters II. Causes: Psychiatric medications s s ( ) ( ) s s ( s) ADHD s III. Causes: Upper Respiratory Medications s (e.g. ) s s IV. Causes: Antihypertensives s (e.g. ) (e.g. ) s (e.g. ) s V. Causes: Miscellaneous medications and drugs Muscle relaxants and antispasmodics s Cannabinoids s Antiparkinsonian agents s (e.g. ) VI. References Images: Related links to external sites (from

2018 FP Notebook

59. Dry Mouth

and Craniofacial Disorders Definition (NCI_NCI-GLOSS) Dry mouth. It occurs when the body is not able to make enough saliva. Definition (NCI_CTCAE) A disorder characterized by reduced salivary flow in the oral cavity. Definition (NCI) An oral condition in which salivary flow is reduced. Definition (CSP) dryness of the mouth due to salivary gland secretion dysfunction. Definition (MSH) Decreased salivary flow. Concepts Sign or Symptom ( T184 ) MSH ICD10 SnomedCT 162014002 , 196513007 , 249425009 , 139281004 (...) , 266425004 , 87715008 , 56893005 LNC MTHU013517 English Asialia , Asialias , Hyposalivation , Hyposalivations , Mouth Dryness , Xerostomia , Xerostomias , APTYALISM , Dryness, Mouth , MOUTH DRY , ORAL DRYNESS , SALIVA DECREASED , XEROSTOMIA , dry mouth , mouth dryness (symptom) , mouth dryness (xerostomia) , mouth dryness , xerostomia (physical finding) , xerostomia , salivary secretion disturbance: xerostomia , xerostomia (diagnosis) , xerostomia was observed , Mouth became dry , Saliva decreased

2018 FP Notebook

60. Effects of combination oral care on oral health, dry mouth and salivary pH of intubated patients: A randomized controlled trial. (Abstract)

Effects of combination oral care on oral health, dry mouth and salivary pH of intubated patients: A randomized controlled trial. Intubated patients are at risk of oral health problems. Although a variety of oral care regimens for intubated patients have been studied, there is a lack of research on the effects of combination oral care that includes tooth brushing, chlorhexidine and cold water. This open-labelled, randomized, controlled trial aimed to evaluate the effects of combination oral care (...) in the control group. The intervention group had better oral health (effect size = 1.56), less dry mouth and higher salivary pH than the control group. Any additional burden of providing combination oral care to patients who are mechanically ventilated is worthwhile in terms of clinical outcomes.© 2016 John Wiley & Sons Australia, Ltd.

2016 International journal of nursing practice Controlled trial quality: uncertain

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