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Dry Mouth

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41. Medication Causes of Dry Mouth

Medication Causes of Dry Mouth Medication Causes of Dry Mouth Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Medication Causes of Dry (...) Mouth Medication Causes of Dry Mouth Aka: Medication Causes of Dry Mouth , Medication Causes of Dry Eyes From Related Chapters II. Causes: Psychiatric medications s s ( ) ( ) s s ( s) ADHD s III. Causes: Upper Respiratory Medications s (e.g. ) s s IV. Causes: Antihypertensives s (e.g. ) (e.g. ) s (e.g. ) s V. Causes: Miscellaneous medications and drugs Muscle relaxants and antispasmodics s Cannabinoids s Antiparkinsonian agents s (e.g. ) VI. References Images: Related links to external sites (from

2018 FP Notebook

42. A Trial Looking at Treating Dry Mouth After Radiotherapy for Head and Neck Cancer

A Trial Looking at Treating Dry Mouth After Radiotherapy for Head and Neck Cancer A Trial Looking at Treating Dry Mouth After Radiotherapy for Head and Neck Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding (...) more. A Trial Looking at Treating Dry Mouth After Radiotherapy for Head and Neck Cancer (LEONIDAS-2) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02941276 Recruitment Status : Completed First Posted : October 21, 2016 Last Update Posted : May 18, 2017 Sponsor: University College, London

2016 Clinical Trials

43. Parasympathomimetic drugs for dry mouth after radiotherapy

Parasympathomimetic drugs for dry mouth after radiotherapy Parasympathomimetic drugs for dry mouth after radiotherapy Search National Elf Service Search National Elf Service » » » » Parasympathomimetic drugs for dry mouth after radiotherapy Oct 9 2015 Posted by Over 90% of patients experience xerostomia during head and neck radiotherapy and for three quarters of patients this can last from one month to 2 years. Xerostomia causes a variety of oral problems including discomfort chewing problems (...) - indications. However, many fail to respond and side effects are common. Another Cochrane review by Furness et al (see Dental Elf 3 rd Sept 2013) looked at non-pharmacological approaches for dry mouth although not specifically related to those patients with radiation-induced xerostomia. They included 9 studies involving acupuncture, electrostimulation devices and powered toothbrushes but the quality of evidence was low or very low. Links Davies AN, Thompson J. Cochrane Database of Systematic Reviews 2015

2015 The Dental Elf

44. Effects of combination oral care on oral health, dry mouth and salivary pH of intubated patients: A randomized controlled trial. (PubMed)

Effects of combination oral care on oral health, dry mouth and salivary pH of intubated patients: A randomized controlled trial. Intubated patients are at risk of oral health problems. Although a variety of oral care regimens for intubated patients have been studied, there is a lack of research on the effects of combination oral care that includes tooth brushing, chlorhexidine and cold water. This open-labelled, randomized, controlled trial aimed to evaluate the effects of combination oral care (...) in the control group. The intervention group had better oral health (effect size = 1.56), less dry mouth and higher salivary pH than the control group. Any additional burden of providing combination oral care to patients who are mechanically ventilated is worthwhile in terms of clinical outcomes.© 2016 John Wiley & Sons Australia, Ltd.

2016 International journal of nursing practice

45. Parasympathomimetic drugs for dry mouth due to radiotherapy. (PubMed)

Parasympathomimetic drugs for dry mouth due to radiotherapy. Data sourcesCochrane Oral Health Group Trials Register, Cochrane Central Register of Controlled Trials, Medline, Embase and CINAHL databases. Reference lists of identified articles were checked and experts in the field and relevant pharmaceutical companies were contacted.Study selectionRandomised controlled trials, including parallel and crossover, carried out in any setting on any patient population with radiation-induced salivary

2016 Evidence Based Dentistry

46. Mouth Care

complications. Key principles Assess every patient Plan regular effective mouth care Confidence to refer Identify urgent referrals. Assessment All patients are at risk of oral problems and will benefit from planned regular mouth care, particularly patients receiving chemotherapy or radiotherapy who will need careful monitoring both pre- and post-treatment. Drug history is significant as numerous medications can affect the oral environment: opioids, diuretics and anticholinergics increase dry mouth steroids (...) increase the risk of candidosis bisphosphonates increase the risk of osteonecrosis of the jaw. Ill-fitting dentures and surgical intervention including tooth extraction increase this risk, highlighting the need for preventative oral hygiene therapy. Ask patients on a daily basis if they are having problems Ensure privacy Remove dentures before examining the mouth or performing routine mouth care Use a torch to thoroughly examine the mouth Check the lining of the mouth is clean. If not, refer to dry

2018 Scottish Palliative Care Guidelines

47. New low-dose liquid pilocarpine formulation for treating dry mouth in Sjögren’s syndrome: clinical efficacy, symptom relief, and improvement in quality of life (PubMed)

New low-dose liquid pilocarpine formulation for treating dry mouth in Sjögren’s syndrome: clinical efficacy, symptom relief, and improvement in quality of life Patients with Sjögren's syndrome (SS) typically present clinically with xerostomia (dry mouth) because of progressive damage to the exocrine glands. We developed a new, low-dose pilocarpine/sodium alginate (LPA) solution with pilocarpine hydrochloride to inhibit systemic adverse effects by administering via the oral mucosa (...) . The purpose of this study was to assess its stability, safety, and efficacy.The pilocarpine concentration in an LPA liquid formulation was measured 3, 7, 14, and 28 days after preparation to assess its stability. A prospective clinical trial was undertaken to assess the efficacy and safety of the LPA solution as a symptomatic treatment for dry mouth in SS. Patients (n = 24) with clinically significant xerostomia were enrolled after providing written informed consent. Whole-mouth salivary flow rate

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2018 Journal of pharmaceutical health care and sciences

48. Dry Eye Disease (KCS)

secondary to long-term topical therapy Symptoms ocular irritation foreign body, gritty or burning sensationp presence of a stringy mucous discharge blurring of vision from epithelial disruption or (transiently) from mucus strands symptoms exacerbated by smoke, wind or heat symptoms usually bilateral; may not be described as a feeling of dryness associated symptoms of dry mouth, systemic disease (e.g. arthritis) Signs reduced tear meniscus at inferior lid margin (following the instillation of fluorescein (...) Dry Eye Disease (KCS) Dry Eye (Keratoconjunctivitis Sicca, KCS) submit The College submit You're here: Dry Eye (Keratoconjunctivitis Sicca, KCS) Dry Eye (Keratoconjunctivitis Sicca, KCS) The CMGs are guidelines on the diagnosis and management of a range of common and rare, but important, eye conditions that present with varying frequency in primary and first contact care. Share options Aetiology The 2017 International Dry Eye Workshop (DEWS II) has provided the following definition: Dry eye

2018 College of Optometrists

49. Insufficient evidence for effects of non-pharmacological interventions for the relief of dry mouth

Insufficient evidence for effects of non-pharmacological interventions for the relief of dry mouth Insufficient evidence for effects of non-pharmacological interventions for the relief of dry mouth Search National Elf Service Search National Elf Service » » » » Insufficient evidence for effects of non-pharmacological interventions for the relief of dry mouth Sep 3 2013 Posted by It has been estimated that between 10-26% of men and 10-33% of women experience dry mouth. The subjective sensation (...) of dry mouth is called xerostomia and can be found in people with normal salivary gland function. The normal range of salivary production ranges from 0.5 to 1.5 litres per day. The aim of this Cochrane review was to assess the effects of non-pharmacological interventions administered to stimulate saliva production for the relief of dry mouth. Searches were conducted in the Cochrane Oral Health Group’s Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, AMED

2013 The Dental Elf

50. The Differential Diagnosis of Dry Eyes, Dry Mouth, and Parotidomegaly: A Comprehensive Review. (PubMed)

The Differential Diagnosis of Dry Eyes, Dry Mouth, and Parotidomegaly: A Comprehensive Review. Primary Sjögren's syndrome (pSS) is a frequent autoimmune systemic disease, clinically characterized by eyes and mouth dryness in all patients, salivary gland swelling or extraglandular systemic manifestations in half of the patients, and development of lymphoma in 5 to 10 % of the patients. However, patients presenting with sicca symptoms or salivary gland swelling may have a variety of conditions (...) that may require very different investigations, treatments, or follow-up. Eye and/or mouth dryness is a frequent complaint in clinical setting, and its frequency increases with age. When evaluating a patient with suspected pSS, the first step is to rule out its differential diagnoses, before looking for positive arguments for the disease. Knowledge of normal and abnormal lachrymal and salivary gland physiology allows the clinician to prescribe the most adapted procedures for evaluating their function

2014 Clinical Reviews in Allergy & Immunology

51. Evidence for the efficacy of clinical methods to assess dry mouth is sparse

Evidence for the efficacy of clinical methods to assess dry mouth is sparse Evidence for the efficacy of clinical methods to assess dry mouth is sparse Search National Elf Service Search National Elf Service » » » » Evidence for the efficacy of clinical methods to assess dry mouth is sparse Aug 10 2012 Posted by Salivary is a complex substance than contains electrolytes, mucus, glycoproteins, enzymes, lysosomes and immunoglobulin. Its normal production is considered important for oral health

2012 The Dental Elf

52. No strong evidence for any topical treatments for relieving the symptoms of dry mouth

No strong evidence for any topical treatments for relieving the symptoms of dry mouth No strong evidence for any topical treatments for relieving the symptoms of dry mouth Search National Elf Service Search National Elf Service » » » » No strong evidence for any topical treatments for relieving the symptoms of dry mouth Jul 11 2012 Posted by The subjective sensation of dry mouth or xerostomia is a common symptom and estimates of the prevalence vary from 10-50%. The Cochrane Collaboration (...) published systematic of topical treatments for reducing the effects of dry mouth in 2011( Furness et al ). Recently the American Dental Association’s Evidence-based Dentistry Center have published a critical summary of this review The summariser notes that the review was of high quality, although, because of the range of interventions and variety of outcome measures only limited meta-analysis could be performed. The review included 36 trials in all, 17 of which were of high risk of bias. 18 of unclear

2012 The Dental Elf

53. Prevention of Dry Socket After Tooth Extraction With Warm Saline Rinses

Prevention of Dry Socket After Tooth Extraction With Warm Saline Rinses UTCAT2996, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Prevention of Dry Socket After Tooth Extraction With Warm Saline Rinses Clinical Question Is warm saline rinse beneficial in preventing alveolar osteitis after dental extraction? Clinical Bottom Line Warm saline mouth rinses 24 hours after dental extraction is helpful in reducing (...) Search Therapy/Broad[filter] AND (("dry socket"[MeSH Terms] Comments on The Evidence Extraction is a routine dental procedure. Warm saline rinse is a common post-operative instruction given to the patient to be followed 24 hours after extraction. These two studies look into the efficacy of saline rinses after non-surgical dental extraction. Both studies were randomized clinical trials. Warm saline rinsing was to start 24 hours after the dental extraction and patients were reviewed at 72 hours

2016 UTHSCSA Dental School CAT Library

54. No strong evidence that any topical treatment is effective for relieving the sensation of dry mouth

No strong evidence that any topical treatment is effective for relieving the sensation of dry mouth No strong evidence that any topical treatment is effective for relieving the sensation of dry mouth - National Elf Service Search National Elf Service Search National Elf Service » » » » No strong evidence that any topical treatment is effective for relieving the sensation of dry mouth Dec 14 2011 Posted by The prevalence of persistent dry mouth varies but a conservative estimates is that about (...) 20% in the general population, with increased prevalence in women (up to 30%) and in the elderly (up to 50%). The aim of this Cochrane review was to determine which topical treatments for dry mouth are effective in reducing this symptom. Detailed searches of a range of databases ( Cochrane Oral Health Group Trials Register, The Cochrane Central Register of Controlled Trials (CENTRAL) MEDLINE , EMBASE, CINAHL, AMED, CANCERLIT) were conducted for randomised controlled trials of topical

2011 The Dental Elf

55. Potential of an Experimental Mouthwash Formulation to Reduce Dry Mouth Symptoms

Potential of an Experimental Mouthwash Formulation to Reduce Dry Mouth Symptoms Potential of an Experimental Mouthwash Formulation to Reduce Dry Mouth Symptoms - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Potential of an Experimental Mouthwash Formulation to Reduce Dry Mouth Symptoms The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02641912 Recruitment Status : Completed First Posted : December 30, 2015 Results First Posted : January 27, 2017 Last Update Posted : July 11, 2017 Sponsor: GlaxoSmithKline

2015 Clinical Trials

56. Changes in Saliva Rheological Properties and Mucin Glycosylation in Dry Mouth. (PubMed)

Changes in Saliva Rheological Properties and Mucin Glycosylation in Dry Mouth. Saliva is vital for the maintenance of normal oral physiology and mucosal health. The loss of salivary function can have far-reaching consequences, as observed with dry mouth, which is associated with increased orodental disease, speech impairment, dysphagia, and a significant negative effect on quality of life. The timely diagnosis of oral dryness is vital for the management of orodental disease and any associated (...) often-undiagnosed systemic disease (e.g., Sjögren syndrome). Our aim was to investigate differences in mucin glycoproteins and saliva rheological properties between sufferers and nonsufferers of dry mouth in order to understand the relationship between saliva composition, rheological properties, and dryness perception and provide additional potential diagnostic markers. All patients exhibited objective and subjective oral dryness, irrespective of etiology. Over half of the patients (n = 20, 58.8

2015 Journal of Dental Research

57. Evaluation of Efficacy of an Herbal Compound on Dry Mouth in Patients With Head and Neck Cancers: A Randomized Clinical Trial. (PubMed)

Evaluation of Efficacy of an Herbal Compound on Dry Mouth in Patients With Head and Neck Cancers: A Randomized Clinical Trial. Dry mouth is a common complication of radiotherapy for head and neck cancers. This study compared the efficacy of an herbal compound containing Malva sylvestris and Alcea digitata (Boiss) with artificial saliva (Hypozalix) for improving the symptoms of dry mouth in head and neck cancer patients. The study examined a total of 62 subjects assigned to 2 groups. The herbal (...) compound and Hypozalix were administered for 4 weeks. Efficacy was assessed using the visual analog scale and by grading the degree of dry mouth. Both groups showed a significant difference between visual analog scale before and following intervention. There was also a significant difference in visual analog scale between groups at 4 weeks after onset of intervention. The herbal group showed a significant difference between the grade of dry mouth before and after intervention, but no change

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2015 Journal of evidence-based complementary & alternative medicine

58. Chlorhexidine gel and less difficult surgeries might reduce post-operative pain, controlling for dry socket, infection and analgesic consumption: a split-mouth controlled randomised clinical trial. (PubMed)

Chlorhexidine gel and less difficult surgeries might reduce post-operative pain, controlling for dry socket, infection and analgesic consumption: a split-mouth controlled randomised clinical trial. Reports on post-surgical pain are a few, controversial and flawed (by statistics and analgesic consumption). Besides, it is not known if chlorhexidine can reduce post-extraction pain adjusting for its effect on prevention of infection and dry socket (DS). We assessed these. A total of 90 impacted (...) mandibular third molars of 45 patients were extracted. Intra-alveolar 0·2% chlorhexidine gel was applied in a split-mouth randomised design to one-half of the sockets. None of the included patients took antibiotics or analgesics afterwards. In the first and third post-operative days, DS formation and pain levels were recorded. Predictive roles of the risk factors were analysed using fixed-effects (classic) and multilevel (mixed-model) multiple linear regressions (α = 0·05, β≤0·1). In the first day, pain

2015 Journal of oral rehabilitation

59. Limited evidence for non-pharmacological interventions for the relief of dry mouth. (PubMed)

Limited evidence for non-pharmacological interventions for the relief of dry mouth. The Cochrane Oral Health Group's Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline, Embase, AMED, CINAHL and CANCERLIT databases were searched. The metaRegister of Controlled Clinical Trials and ClinicalTrials.gov were also searched to identify ongoing and completed trials. Reference lists of included studies and relevant reviews were also searched. There were no restrictions (...) on the language of publication or publication status.Randomised controlled trials of non-pharmacological treatments for patients with dry mouth at baseline.Study assessment and data extraction were carried out independently by at least two reviewers. Mean difference (MD) and standardised mean differences (SMD) together with 95% CIs were calculated where appropriate.Nine studies (366 participants) were included in this review, eight were assessed at high risk of bias and one at unclear risk of bias. Five small

2014 Evidence Based Dentistry

60. The effect of cognitive appraisal for stressors on the oral health-related QOL of dry mouth patients (PubMed)

The effect of cognitive appraisal for stressors on the oral health-related QOL of dry mouth patients Dry mouth is very common symptom, and psychological factors have an influence on this symptom. Although the influence of emotional factor related to patients with oral dryness has been examined in previous studies, the cognitive factors have not been examined thus far.The purpose of this study was to examine the influence of cognitive factors on patients with oral dryness.The participants were

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2014 BioPsychoSocial medicine

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