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Double-Crush Syndrome

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1. Double Crush Syndrome

Double Crush Syndrome Double Crush Syndrome | Carpal-Tunnel.net Double Crush Syndrome The original version of this article was written as a reponse to a question on a bulletin board by a patient and it has been revised for this website. Another very sensible review of the topic by an academic chiropractor can be read . The term ‘double crush syndrome’ originates from work published by and as such it would follow established practice if their original statement of the hypothesis were to become (...) the working definition of 'double crush'. The abstract of their paper read as follows: "A comprehensive electromyographic study has been made of 115 patients with carpal-tunnel syndromes or lesions of the ulnar nerve at the elbow. In 81 cases there was electrophysiological evidence, often supported by clinical symptoms, of associated neural lesions in the neck. This association is not thought to be fortuitous, but rather the result of serial constraints of axoplasmic flow in nerve fibres." However, I have

2012 Carpal-Tunnel.net

2. Double crush syndrome caused by cervical spondylosis and vertebral artery loop. (PubMed)

Double crush syndrome caused by cervical spondylosis and vertebral artery loop. The purpose of this article is to report a successful treatment experience in a rare case of simultaneous cervical nerve root compression by spondylotic cervical foraminal stenosis and a vertebral artery loop.51-year-old man presented with a 4-year history of left-sided cervical pain radiating to the left shoulder with progressive exacerbation of weakness on left shoulder girdle muscles for 7 months. The patient had (...) girdle returned normal.This report illustrates the first phenomenon of a double crush syndrome caused by vertebral artery loop and cervical spondylotic changes. When patients with cervical spondylosis present with unexplainably severe pain and weakness, additional underlying pathologies should be considered when making differential diagnoses. The investigation planning should involve electromyography, computed tomography angiography, and magnetic resonance imaging.

2017 European Spine Journal

3. Ipsilateral radial nerve, median nerve, and ulnar nerve injury caused by crush syndrome due to alcohol intoxication: A case report. (PubMed)

Ipsilateral radial nerve, median nerve, and ulnar nerve injury caused by crush syndrome due to alcohol intoxication: A case report. Autologous peripheral nerve injury caused by crush syndrome due to alcohol intoxication is relatively rare, and to our knowledge, the compression of 3 upper limb nerves at the same time has not been reported previously. If a compressive peripheral nerve injury is not treated in a timely manner, it is difficult to recover neurological function, and the prognosis

2019 Medicine

4. Multifocal Neuropathy: Expanding the Scope of Double Crush Syndrome. (PubMed)

Multifocal Neuropathy: Expanding the Scope of Double Crush Syndrome. Double crush syndrome (DCS), as it is classically defined, is a clinical condition composed of neurological dysfunction due to compressive pathology at multiple sites along a single peripheral nerve. The traditional definition of DCS is narrow in scope because many systemic pathologic processes, such as diabetes mellitus, drug-induced neuropathy, vascular disease and autoimmune neuronal damage, can have deleterious effects

2016 Journal of Hand Surgery - American

5. Outcomes following peripheral nerve decompression with and without associated double crush syndrome: a case control study. (PubMed)

Outcomes following peripheral nerve decompression with and without associated double crush syndrome: a case control study. Double crush syndrome, the association between proximal and distal nerve lesions, has been established. This investigation compares the outcomes of nerve surgery in patients with isolated peripheral compression versus those with double crush syndrome treated with peripheral nerve and cervical spine operations.This case-controlled study enrolled 80 patients: 40 underwent (...) surgery, patients with a history of cervical spine surgery are likely to have inferior patient-reported outcomes, persistent nerve dysfunction, and lower satisfaction after peripheral nerve release compared with patients following isolated peripheral nerve surgery. Double crush syndrome was associated with poorer outcome after peripheral nerve surgery despite treatment of cervical spine nerve compression.Therapeutic, III.

2016 Plastic and reconstructive surgery

6. Ultrasound Diagnosis of Double Crush Syndrome of the Ulnar Nerve by the Anconeus Epitrochlearis and a Ganglion (PubMed)

Ultrasound Diagnosis of Double Crush Syndrome of the Ulnar Nerve by the Anconeus Epitrochlearis and a Ganglion Double compression of the ulnar nerve, including Guyon's canal syndrome associated with cubital tunnel syndrome caused by the anconeus epitrochlearis muscle, is a very rare condition. We present a case of double crush syndrome of the ulnar nerve at the wrist and elbow in a 55-year-old man, as well as a brief review of the literature. Although electrodiagnostic findings were consistent

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2016 Journal of Korean Neurosurgical Society

7. Double-Crush Syndrome

Double-Crush Syndrome Double-Crush Syndrome Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Double-Crush Syndrome Double-Crush (...) Syndrome Aka: Double-Crush Syndrome From Related Chapters II. Pathophysiology compression at two sites Cervical disc and Cervical compression predisposes to more susceptible to injury III. Causes Proximal Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Double-Crush Syndrome." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Wrist Disorders

2018 FP Notebook

8. Loading with Oral P2Y12 Receptor Inhibitors: To Crush or Not to Crush? (PubMed)

Loading with Oral P2Y12 Receptor Inhibitors: To Crush or Not to Crush? Oral P2Y12 receptor inhibitors represent a mainstay treatment in patients with acute coronary syndrome and those undergoing percutaneous coronary intervention. In the setting of ST-elevation myocardial infarction, when early platelet inhibition is highly desirable, the onset of action of oral P2Y12 receptor inhibitors is, however, delayed, likely due to delayed drug absorption. Crushing the tablets, which are to be used (...) for patient loading with an oral P2Y12 receptor inhibitor, has been shown to provide earlier platelet inhibition than standard, integral tablets administration. Chewed ticagrelor tablets may also result in a similar effect. Such findings should be interpreted with caution, mainly due to the small number of patients enrolled and the nature (pharmacodynamic/pharmacokinetic) of the respective studies. Furthermore, in patients with out-of-hospital cardiac arrest, who remain comatose, crushing tablets

2019 Thrombosis and haemostasis

9. A historical perspective on crush syndrome: the clinical application of its pathogenesis, established by the study of wartime crush injuries. (PubMed)

A historical perspective on crush syndrome: the clinical application of its pathogenesis, established by the study of wartime crush injuries. Crush syndrome is a fine example of how pathology can play a direct role in revealing the best treatment and management for diseases. It can occur when crush injuries are sustained. Skeletal muscle becomes damaged under the weight of a heavy object, and victims experience severe shock and renal failure. The discovery of the pathology of crush syndrome (...) belongs to two individuals: Seigo Minami and Eric Bywaters. They separately helped to define the pathogenesis of crush syndrome during World Wars I and II. Seigo Minami is believed to have been the first to record the pathogenesis of crush syndrome. In 1923, he described the cases of three soldiers who died of renal failure caused by crush injury during World War I. Using microscopic studies to investigate the pathology of their kidneys, he found the soldiers had died due to 'autointoxication' caused

2016 Journal of Clinical Pathology

10. Beneficial effects of antioxidant therapy in crush syndrome in a rodent model: enough evidences to be used in humans? (PubMed)

Beneficial effects of antioxidant therapy in crush syndrome in a rodent model: enough evidences to be used in humans? 30264204 2018 11 14 2110-5820 8 1 2018 Sep 27 Annals of intensive care Ann Intensive Care Beneficial effects of antioxidant therapy in crush syndrome in a rodent model: enough evidences to be used in humans? 96 10.1186/s13613-018-0431-5 Honore Patrick M PM ICU Department, Centre Hospitalier Universitaire Brugmann, 4, Place Arthur Van Gehuchten, 1020, Brussels, Belgium (...) . Patrick.Honore@CHU-Brugmann.be. De Bels David D ICU Department, Centre Hospitalier Universitaire Brugmann, 4, Place Arthur Van Gehuchten, 1020, Brussels, Belgium. Spapen Herbert D HD Universitair Ziekenhuis Brussel, VUB University, Brussels, Belgium. eng Editorial 2018 09 27 Germany Ann Intensive Care 101562873 2110-5820 Antioxidant therapy Astragaloside IV Crush syndrome Ischemia–reperfusion injury Rhabdomyolysis 2018 05 13 2018 08 24 2018 9 29 6 0 2018 9 29 6 0 2018 9 29 6 1 epublish 30264204 10.1186

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2018 Annals of intensive care

11. Bathroom Entrapment Leading to Cardiac Arrest From Crush Syndrome. (PubMed)

Bathroom Entrapment Leading to Cardiac Arrest From Crush Syndrome. Crush injuries have the potential to cause life-threatening systemic effects such as hyperkalemia, dysrhythmias, acute kidney injury, and renal failure. Systemic involvement is known as crush syndrome (CS) and results from tissue ischemia and muscle necrosis. This is a report of a 76-year-old female who developed a fatal dysrhythmia following release of her extremity from prolonged entrapment in bathroom safety equipment (...) . Hyperkalemia should be presumed in any crush injury and be treated empirically and aggressively. Although tourniquet application prior to extrication is not widely recommended to prevent CS, it should be considered in prolonged extremity entrapment.

2018 Prehospital emergency care

12. Nitrite as a pharmacological intervention for the successful treatment of crush syndrome (PubMed)

Nitrite as a pharmacological intervention for the successful treatment of crush syndrome Crush syndrome is characterized by ischemia/reperfusion injury (IRI). The protective effect of nitrite on experimentally induced IRI has been demonstrated in the heart, kidney, liver, and skeletal muscle. IRI in tissues and systemic organs occurs due to the massive generation of reactive oxygen species and subsequent systemic inflammation. Therefore, ischemic pre and postconditioning are performed (...) in clinical practice. Intravenous administration of nitrite inhibits IRI through nitric oxide-mediated mechanisms. In this paper, we discuss the utility of nitrite as a pharmacological postconditioning agent in the treatment of crush syndrome.© 2018 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

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2018 Physiological reports

13. Effect of Raw Crushed Garlic (Allium sativum L.) on Components of Metabolic Syndrome. (PubMed)

Effect of Raw Crushed Garlic (Allium sativum L.) on Components of Metabolic Syndrome. Metabolic syndrome consists of a group of risk factors characterized by abdominal obesity, hypertension, atherogenic dyslipidemia, hyperglycemia, and prothrombotic and proinflammatory conditions. Raw garlic homogenate has been reported to reduce serum lipid levels in animal model; however, no precise studies have been performed to evaluate the effect of raw crushed garlic (Allium sativum L.) on components (...) of metabolic syndrome. Therefore, the present study was designed to investigate the effect of raw crushed garlic on components of metabolic syndrome. A total of 40 metabolic syndrome patients were randomly selected from the diabetic center of SP Medical College, Bikaner, Rajasthan, India. They underwent treatment with 100 mg/kg body weight raw crushed garlic 2 times a day with standard diet for 4 weeks; their anthropometric and serum biochemical variables were measured at both the beginning and the end

2018 Journal of dietary supplements Controlled trial quality: uncertain

14. Double Crush of L5 Spinal Nerve Root due to L4/5 Lateral Recess Stenosis and Bony Spur Formation of Lumbosacral Transitional Vertebra Pseudoarticulation: A Case Report and Review (PubMed)

Double Crush of L5 Spinal Nerve Root due to L4/5 Lateral Recess Stenosis and Bony Spur Formation of Lumbosacral Transitional Vertebra Pseudoarticulation: A Case Report and Review We present a case of double-crushed L5 nerve root symptoms caused by inside and outside of the spinal canal with spur formation of the lumbosacral transitional vertebra (LSTV). A 78-year-old man presented with 7-year history of moderate paresis of his toe and left leg pain when walking. Magnetic resonance imaging (MRI (...) Wiltse approach, resulting in the improvement of his symptoms. The impingement of L5 spinal nerve root between the transverse process of the fifth lumbar vertebra and the sacral ala is a rare entity of the pathology called "far-out syndrome (FOS)". Especially, the bony spur formation secondary to the anomalous articulation of the LSTV (LSPA) has not been reported. These articulations could be due to severe disc degeneration, following closer distance and contact between the transverse process

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2017 NMC Case Report Journal

15. 20-Day Trend of Serum Potassium Changes in Bam Earthquake Victims with Crush Syndrome; a Cross-sectional Study (PubMed)

20-Day Trend of Serum Potassium Changes in Bam Earthquake Victims with Crush Syndrome; a Cross-sectional Study Many of those who survive following an earthquake die in the next phase due to preventable and treatable medical conditions such as hyperkalemia. The present study aimed to evaluate the trend of potassium changes in crush syndrome patients of Bam earthquake.In this retrospective cross-sectional study, using the database of Bam earthquake victims, which were developed by Iranian Society (...) of Nephrology following Bam earthquake, Iran, 2003, the 20-day trend of potassium changes in > 15 years old crush syndrome patients was evaluated.135 crush syndrome patients with the mean age of 29.9 ± 9.91 years were evaluated (56.3% male). Mean potassium concentration during the first 3 days of admission was 5.6 ± 1.3 mEq/L. On the day of admission, 43.1% (95% CI: 34.0 - 52.2) had normal potassium concentration, 3.4% (95% CI: 0.1 - 6.8) had hypokalemia, and 53.4% (44.3 - 62.6) had hyperkalemia. During 20

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2017 Emergency

16. Trends of Serum Electrolyte Changes in Crush syndrome patients of Bam Earthquake; a Cross sectional Study (PubMed)

Trends of Serum Electrolyte Changes in Crush syndrome patients of Bam Earthquake; a Cross sectional Study Electrolyte imbalances are very common among crushed earthquake victims but there is not enough data regarding their trend of changes. The present study was designed to evaluate the trend of changes in sodium, calcium, and phosphorus ions among crush syndrome patients.In this retrospective cross-sectional study, using the database of Bam earthquake victims, which was developed by Iranian (...) Society of Nephrology following Bam earthquake, Iran, 2003, the 10-day trend of sodium, calcium, and phosphorus ions changes in > 15 years old crush syndrome patients was evaluated.118 patients with the mean age of 25.6 ± 6.9 years were studied (57.3 male). On the first day of admission, 52.5% (95% CI: 42.7 - 62.3) of the patients had hyponatremia, which reached 43.9% (95% CI: 28.5 - 59.3) on day 10. 100.0% of patients were hypocalcemic on admission and serum calcium level did not change dramatically

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2017 Emergency

17. Astragaloside-IV prevents acute kidney injury and inflammation by normalizing muscular mitochondrial function associated with a nitric oxide protective mechanism in crush syndrome rats (PubMed)

Astragaloside-IV prevents acute kidney injury and inflammation by normalizing muscular mitochondrial function associated with a nitric oxide protective mechanism in crush syndrome rats Crush syndrome (CS) is a serious medical condition characterized by muscle cell damage resulting from decompression after compression (i.e., ischemia/reperfusion injury). A large number of CS patients develop cardiac failure, kidney dysfunction, and systemic inflammation, even when fluid therapy is administered

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2017 Annals of intensive care

18. Compartment and Crush Syndromes After Sleep Deprivation and a Therapeutic Dose of Zolpidem (PubMed)

Compartment and Crush Syndromes After Sleep Deprivation and a Therapeutic Dose of Zolpidem Despite extensive review in the literature, compartment syndrome and crush syndrome remain difficult to diagnose. Trauma, toxins and reperfusion have been associated with these syndromes. Cases involving alcohol and drug abuse have described patients "found down" compressing an extremity. We present a case of a registered nurse who developed compartment syndrome in multiple limbs due to prolonged sleep (...) after sleep deprivation and zolpidem use. To our knowledge, this is the first case of compartment syndrome or crush syndrome to have occurred in the setting of zolpidem use. Sleep disruption in healthcare workers represents a public health issue with dangerous sequelae, both acute and chronic.

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2017 Clinical Practice and Cases in Emergency Medicine

19. TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study)

TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study) TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search (...) for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. TASK-002: Bioequivalence of Bedaquiline 400mg Administered in Crushed Form Compared to Tablet Form in Healthy Male and Female Adults Under Fed Conditions (BDQ Crush Study) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has

2017 Clinical Trials

20. A Study to Assess the Absorption of a Single Dose of BMS-986205 in Healthy Volunteers When Administered as a Crushed Tablet Orally or Crushed Tablet Suspension Via Nasogastric Tube, as Compared to a Tablet

A Study to Assess the Absorption of a Single Dose of BMS-986205 in Healthy Volunteers When Administered as a Crushed Tablet Orally or Crushed Tablet Suspension Via Nasogastric Tube, as Compared to a Tablet A Study to Assess the Absorption of a Single Dose of BMS-986205 in Healthy Volunteers When Administered as a Crushed Tablet Orally or Crushed Tablet Suspension Via Nasogastric Tube, as Compared to a Tablet - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers (...) : refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study to Assess the Absorption of a Single Dose of BMS-986205 in Healthy Volunteers When Administered as a Crushed Tablet Orally or Crushed Tablet Suspension Via Nasogastric Tube, as Compared to a Tablet The safety and scientific validity

2017 Clinical Trials

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