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12481. Total mesorectal excision (TME) with or without preoperative radiotherapy in the treatment of primary rectal cancer. Prospective randomised trial with standard operative and histopathological techniques. Dutch ColoRectal Cancer Group. Full Text available with Trip Pro

and within the participating disciplines goes well. With regard to the surgical part, this can be confirmed by the large number of operations attended by consultant surgeons (58%). The number of abdominoperineal resections appeared to be low (30%), as did the percentage of lateral margins involved (13%). The rate of adverse effects of radiotherapy was acceptable. Apart from a larger operative blood loss and a higher infective complication rate in the irradiated group, no significant differences were

1999 The European journal of surgery = Acta chirurgica Controlled trial quality: uncertain

12482. Behavioural intervention trials for HIV/STD prevention in schools: are they feasible? Full Text available with Trip Pro

considerable enthusiasm for peer led education, among peer educators and year 9 pupils. Class discipline was the most frequently noted problem with the delivery of the peer led intervention.Evaluation of a peer led behavioural intervention through an RCT can be acceptable to schools, pupils, and parents and is feasible in practice. In general, pupils who received the peer led intervention responded more positively than those in control schools. A large RCT of the long term (5-7 year) effects of this novel

1998 Sexually transmitted infections Controlled trial quality: uncertain

12483. Treatment of young children's bedtime refusal and nighttime wakings: a comparison of "standard" and graduated ignoring procedures. (Abstract)

in the graduated ignoring group reported higher rates of compliance and less treatment-related stress. Maternal characteristics predicted treatment outcome in the standard ignoring condition. Following treatment, only positive side effects were observed. When compared to the wait-list group, mothers in the standard ignoring group reported less verbose discipline and decreased stress in parenting, while mothers in the graduated ignoring group reported improved parent-child relationships. Treatment gains were

1999 Journal of abnormal child psychology Controlled trial quality: uncertain

12484. A multifactorial study of age bias among rehabilitation professionals. (Abstract)

A multifactorial study of age bias among rehabilitation professionals. To assess different dimensions of age bias among rehabilitation professionals and to determine the effect of patient gender and behavior on these biases.Between-subjects questionnaire study.Randomly selected institutions accredited with the Commission on the Accreditation of Rehabilitation Facilities (CARF).Nine hundred seventy-four rehabilitation professionals from 9 disciplines at 23 CARF-accredited facilities.Each

2001 Archives of physical medicine and rehabilitation Controlled trial quality: uncertain

12485. Continuous quality improvement in medicine: validation of a potential role for medical specialty societies. (Abstract)

an impact on the adoption of care processes into national practice. This Society CQI Platform is a potential model for large-scale quality improvement efforts across all disciplines of medicine.

2003 The American heart hospital journal Controlled trial quality: uncertain

12486. Collaborative practice: development, implementation, and evaluation of a weaning protocol for patients receiving mechanical ventilation. (Abstract)

. Although length of stay in the intensive care unit was not significantly reduced (P = .29), a continuing downward trend occurred, from a mean of 8.6 days before the protocol was implemented to 7.9 days during the last 6 months of data collection (P = .07).The need to provide efficient care requires the collaboration of all disciplines involved in providing patients' care. The weaning protocol introduced in this study demonstrates the benefits of using a collaborative team to identify best practices

2003 American Journal of Critical Care

12487. Recommendations for the relationship between sponsors and investigators in the design and conduct of clinical stroke trials. Full Text available with Trip Pro

concerning required sponsor company qualities, trial management structure, protocol development, trial conduct, data management, blinding, data analyses, publication, remuneration, and conflict of interest issues.The recommendations should provide a simple and practical benchmark for both investigators and sponsors in the conduct of clinical trials. Although designed for trials involving therapies for stroke, the framework allows generalization to other disciplines.

2003 Stroke

12488. Care and outcomes of patients newly hospitalized for heart failure in the community treated by cardiologists compared with other specialists. Full Text available with Trip Pro

in processes of care and clinical outcomes between patients attended by physicians of different disciplines. We found that patients attended by cardiologists had lower 1-year risk-adjusted mortality than those attended by general internists, family practitioners, and other physicians (28.5% versus 31.7%, 34.9%, and 35.9%, respectively; all pairwise comparisons, P<0.001). The 1-year risk-adjusted composite outcome of death and readmission for heart failure was also lower for the cardiologists compared

2003 Circulation

12489. Vitamin C metabolomic mapping in the lens with 6-deoxy-6-fluoro-ascorbic acid and high-resolution 19F-NMR spectroscopy. (Abstract)

Vitamin C metabolomic mapping in the lens with 6-deoxy-6-fluoro-ascorbic acid and high-resolution 19F-NMR spectroscopy. Metabolomics, or metabolic profiling, is an emerging discipline geared to providing information on a large number of metabolites, as a complement to genomics and proteomics. In the current study, a fluorine-labeled derivative of ascorbic acid (F-ASA), a major antioxidant- and UV-trapping molecule in the aqueous humor and the lens, was used to investigate the extent to which

2003 Investigative Ophthalmology & Visual Science

12490. Pathology tests: is the time for demand management ripe at last? Full Text available with Trip Pro

Pathology tests: is the time for demand management ripe at last? With the ever increasing demands for pathology testing within the National Health Service there is a need to manage the demand for these tests. This review discusses strategies for the demand management of requests made by clinicians in the disciplines of biochemistry, haematology, and microbiology. The various approaches that have been used to manage demand will be described, along with specific clinical strategies for demand

2003 Journal of Clinical Pathology

12491. Misrepresentation of research publications among orthopedic surgery fellowship applicants: a comparison with documented misrepresentations in other fields. (Abstract)

fellowships is intense. The applicant pool includes orthopedic, plastic, and general surgeons, as well as neurosurgeons. Residency and fellowship training programs in other disciplines have documented shocking levels of misrepresentation in the curriculum vitae of prospective applicants. However, no study has looked at orthopedic residents applying for subspecialty fellowship programs. Methods. A retrospective analysis investigated 280 applications for fellowship positions in the department of orthopedic

2003 Spine

12492. Carl Nicoladoni and his contributions to scoliosis. (Abstract)

Carl Nicoladoni and his contributions to scoliosis. Carl Nicoladoni (1847-1902) studied medicine in Vienna and became Privatdozent in surgery in 1876. He accepted a chair as a Professor of Surgery at the university clinics of Innsbruck (1881) and Graz (1895). Nicoladoni has made significant contributions in the progress of surgery and performed a variety of operations in several surgical disciplines. However, his principal contributions are in the field of orthopedic surgery, in particular his

2003 Spine

12493. Key pollen allergens in North America. (Abstract)

the field of allergy should be to identify high-priority targets for future development of standardized commercial extracts. The standardization of increasing numbers of allergen extracts potentially benefits the discipline of allergy by facilitating transfer of care among physician practices, improving uniformity of patient care, and providing a template on which geographically specific extract choices can be built.

2003 Asthma & Immunology

12494. Minimally invasive lumbar fusion. (Abstract)

Minimally invasive lumbar fusion. Review article.To provide an overview of current techniques for minimally invasive lumbar fusion.Minimally invasive techniques have revolutionized the management of pathologic conditions in various surgical disciplines. Although these same principles have been used in the treatment of lumbar disc disease for many years, minimally invasive lumbar fusion procedures have only recently been developed. The goals of these procedures are to reduce the approach-related

2003 Spine

12495. Misrepresentation of research publications among orthopedic surgery fellowship applicants: a comparison with documented misrepresentations in other fields. (Abstract)

orthopedic, plastic, and general surgeons, as well as neurosurgeons. Residency and fellowship training programs in other disciplines have documented shocking levels of misrepresentation in the curriculum vitae of prospective applicants. However, no study has looked at orthopedic residents applying for subspecialty fellowship programs.A retrospective analysis investigated 280 applications for fellowship positions in the department of orthopedic surgery at the authors' academic institution from 1996

2003 Spine

12496. Regulatory compliance issues in behavioral health. (Abstract)

Regulatory compliance issues in behavioral health. Behavioral health as a discipline has grappled with regulatory compliance issues on its own, tending to be isolated from other specialties and to benefit little from the mistakes and solutions of the rest of medicine. The most common problems with behavioral health regulatory compliance have to do with documentation, billing and coding, treatment plans, and medical necessity. Regulatory compliance is inextricably linked to quality of care

2003 Journal for Healthcare Quality

12497. Ancillary services in the health care industry: is Six Sigma reasonable? (Abstract)

Ancillary services in the health care industry: is Six Sigma reasonable? Within the naval medical center construct, the disparate disciplines encompassed within ancillary services lend themselves to formal quality analysis and process improvement. This analysis uses the Six Sigma approach. Error rates were investigated and calculated for various processes within ancillary services at Naval Medical Center, San Diego. These were translated into the common metric of defects per million

2003 Quality Management in Health Care

12498. Immune mechanisms in bacillus Calmette-Guerin immunotherapy for superficial bladder cancer. (Abstract)

Immune mechanisms in bacillus Calmette-Guerin immunotherapy for superficial bladder cancer. Of all medical disciplines it is exclusively in urology in which immunotherapy for cancer has an established position today with intravesical bacillus Calmette-Guerin (BCG) against superficial bladder carcinoma recurrences. BCG is regarded as the most successful immunotherapy to date. However, the mode of action has not yet been fully elucidated. We provide a thorough overview of this complex field

2003 Journal of Urology

12499. Structural biology: a high-tech tool for biomedical research. (Abstract)

Structural biology: a high-tech tool for biomedical research. Structural biology is one of the most informative disciplines available to biochemical research. It unites technologies that can reveal high-resolution (often atomic) details of the inner workings of biochemical systems. These insights are crucial for an understanding of basic life processes, such as the reaction mechanism of a drug-converting enzyme, signal transduction from one protein to another, activation of a metabolic pathway

2003 Current Opinion in Nephrology and Hypertension

12500. Teaching and training in old age psychiatry: a general survey of the World Psychiatric Association member societies. Full Text available with Trip Pro

Teaching and training in old age psychiatry: a general survey of the World Psychiatric Association member societies. One of the main goals of the World Psychiatric Association (WPA) section on old age psychiatry is to promote its discipline and consequently to help member societies to promote and develop locally specific medical education programmes in old age psychiatry. In order to target its support to the needs expressed by the member societies, the section conducted a survey within the WPA (...) during the year 2001.A questionnaire was sent to each of the 116 WPA member societies in 93 countries. It assessed the level of development of medical education in old age psychiatry in each country, as well as the perceived needs in educational material.Answers were obtained from 50 WPA member societies (response rate 54%) from 48 countries (response rate 52%). The existence of specific old age psychiatry services was reported in 40 (83%) countries, but the discipline is recognized as a subspecialty

2003 International Journal of Geriatric Psychiatry

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