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Diarrhea Secondary to Medications

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141. Proof-of-Concept Study in Cancer Patients to Assess Efficacy of Elsiglutide in Preventing Chemotherapy-Induced Diarrhea

days from Day 1 chemotherapy Placebo Comparator: Placebo Drug: Placebo 24 mg administered s.c. once daily for 4 consecutive days from Day 1 chemotherapy Outcome Measures Go to Primary Outcome Measures : Number of Patients experiencing Diarrhea [ Time Frame: Day 1 to Day 14 ] Severity of Diarrhea will be classified according to the NCI-CTCAE. Secondary Outcome Measures : Safety and tolerability of the administered repeated doses of elsiglutide (ZP1846) will be evaluated [ Time Frame: Day 1 to Day 32 (...) Proof-of-Concept Study in Cancer Patients to Assess Efficacy of Elsiglutide in Preventing Chemotherapy-Induced Diarrhea Proof-of-Concept Study in Cancer Patients to Assess Efficacy of Elsiglutide in Preventing Chemotherapy-Induced Diarrhea - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2012 Clinical Trials

142. Trial Of Azithromycin In Campylobacter Concisus Patients With Diarrhea

Comparator: azithromycin azithromycin 500mg Drug: azithromycin azithromycin, oral use, 500mg per day for 3 days in total. Total dose 1500mg Other Name: zitromax Placebo Comparator: placebo placebo 500mg Drug: Placebo Outcome Measures Go to Primary Outcome Measures : Duration of diarrhea in days [ Time Frame: up to 10 days ] Secondary Outcome Measures : number of stools/day [ Time Frame: one day ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate (...) prolongation. Patients treated with other active drugs that prolong the QT interval such as: antiarrhythmics of classes IA and III, cisapride and terfenadine. Patients with electrolyte disorders, particularly hypokalemia and hypomagnesemia. Patients with clinically relevant bradycardia, arrhythmia or severe heart failure. Inflammatory bowel diseases Chronic diarrhea of known cause. Dementia. Serious illness less than 21 days from the planned entry into the study. Patients treated with medications that have

2012 Clinical Trials

143. Probiotic in Irritable Bowel Syndrome (IBS) Patients With Diarrhea

Bowel Syndrome (IBS) Patients With Diarrhea (IBS-D) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01667627 Recruitment Status : Completed First Posted : August 17, 2012 Last Update Posted : May 24, 2018 Sponsor: Tel-Aviv Sourasky Medical Center Information provided by (Responsible Party): Tel-Aviv (...) : Roy Dekel, MD Tel Aviv Medical Center More Information Go to Layout table for additonal information Responsible Party: Tel-Aviv Sourasky Medical Center ClinicalTrials.gov Identifier: Other Study ID Numbers: TASMC-11-RD-0491-CTIL First Posted: August 17, 2012 Last Update Posted: May 24, 2018 Last Verified: May 2018 Keywords provided by Tel-Aviv Sourasky Medical Center: IBS Probiotic hs-CRP Cholinergic status Micro-inflammation Additional relevant MeSH terms: Layout table for MeSH terms Diarrhea

2012 Clinical Trials

144. Lactobacillus Reuteri DSM 17938 in Preventing Nosocomial Diarrhea in Children

. Lactobacillus Reuteri DSM 17938 in Preventing Nosocomial Diarrhea in Children The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01968408 Recruitment Status : Completed First Posted : October 24, 2013 Last Update Posted : June 18, 2015 Sponsor: Medical University of Warsaw Information provided by (Responsible (...) Party): Hanna Szajewska, Medical University of Warsaw Study Details Study Description Go to Brief Summary: AIM: To determine the efficacy of Lactobacillus reuteri DSM 17938 at a dose of 10(9) CFU for the prevention of nosocomial diarrhea. TRIAL DESIGN: Double-blind, placebo controlled RCT. INTERVENTION: L reuteri DSM 17938 in a daily dose of 10(9) CFU. PRIMARY OUTCOME: Nosocomial diarrhoea (3 or more loose or watery stools in a 24 h that will occur more than 72 h after admission). Condition

2012 Clinical Trials

145. The Efficacy of CASAD in Patients With Diarrhea Related to Medullary Thyroid Cancer

the severity of diarrhea after 1 week of treatment in patients with MTC. Secondary Outcome Measures : Functional impact of CASAD [ Time Frame: 1 week ] To explore the functional impact of CASAD and the relative impact of diarrhea in relation to other symptom issues using MDASI-THY (M.D. Anderson Symptom Inventory-Thyroid, appendix D) Effect on thyroid function tests [ Time Frame: 1 week ] To explore the effect of CASAD on thyroid function tests, thyroid hormone and calcium absorption Changes in MDASI-THY (...) The Efficacy of CASAD in Patients With Diarrhea Related to Medullary Thyroid Cancer The Efficacy of CASAD in Patients With Diarrhea Related to Medullary Thyroid Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2012 Clinical Trials

146. Lactobacillus Preparation on the Incidence of Diarrhea

of probiotics till the day of 1st diarrhea. If patients are transferred to ward, this study ends in each patient. Secondary Outcome Measures : 28day-mortality [ Time Frame: 28 day ] Mortality in 28th day of ICU residence Positive results of C.difficile toxin [ Time Frame: The first onset of diarrhea during ICU residence (up to 8 weeks) ] If diarrhea (>600ml/day) occurs during ICU residence, we will perform C.difficile toxin assays to determine the cause of diarrhea. ICU-acquired pneumonia [ Time Frame (...) Lactobacillus Preparation on the Incidence of Diarrhea Lactobacillus Preparation on the Incidence of Diarrhea - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Lactobacillus Preparation on the Incidence

2012 Clinical Trials

147. Safety Study of Chimeric Vaccine to Prevent ETEC Diarrhea

to Prevent ETEC Diarrhea The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01644565 Recruitment Status : Unknown Verified October 2015 by U.S. Army Medical Research and Materiel Command. Recruitment status was: Active, not recruiting First Posted : July 19, 2012 Last Update Posted : November 2, 2015 Sponsor (...) Safety Study of Chimeric Vaccine to Prevent ETEC Diarrhea Safety Study of Chimeric Vaccine to Prevent ETEC Diarrhea - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Safety Study of Chimeric Vaccine

2012 Clinical Trials

148. Probiotic Supplementation in Preventing Treatment-Related Diarrhea in Patients With Cancer Undergoing Chemotherapy

/severe (grade 2-4) diarrhea graded according to Common Terminology Criteria for Adverse Events (CTCAE) version 4.0. II. Functional Assessment of Chronic Illness Therapy - Diarrhea (FACIT-D) Trial Outcome Index. SECONDARY OBJECTIVES: I. To evaluate the effects of probiotic supplementation on dose delays or reductions due to gastrointestinal (GI) toxicity. II. To evaluate the effects of probiotic supplementation on anti-diarrheal medication use. III. To evaluate the effects of probiotic supplementation (...) and conventional cytotoxic chemotherapy will be analyzed both combined and separately. FACIT-D Trial Outcome Index (TOI) [ Time Frame: Up to 4 weeks post treatment ] The FACIT-D TOI has a range of scores from 0-100 which are a combination of physical well being, functional well being, and diarrhea subscale. The data for patients on tyrosine kinase inhibitors and conventional cytotoxic chemotherapy will be analyzed both combined and separately. Secondary Outcome Measures : Dose delays or reductions due to GI

2012 Clinical Trials

149. Diarrhea in HIV

) These images are a random sampling from a Bing search on the term "Diarrhea in HIV." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Diarrhea About FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency clinicians. Started in 1995, this collection now contains 6656 interlinked topic pages divided into a tree of 31 specialty books and 728 chapters. Content (...) Diarrhea in HIV Diarrhea in HIV Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Diarrhea in HIV Diarrhea in HIV Aka: Diarrhea in HIV

2015 FP Notebook

150. Acute Diarrhea

, Diarrhea , Acute Infectious Diarrhea , Infectious Diarrhea , Bacterial Diarrhea From Related Chapters II. Definition Inflammation of the gastrointestinal tract ( e and ) Typical presentation is followed by Diarrhea Most typically secondary to Can also be caused by with ingestion of preformed toxin Diarrhea Frequent liquid stools Adults: >200 g/day of stool (at least 3 s daily) Children: >20 g/kg/day of stool Timing Acute Diarrhea: Duration <2 weeks : Duration >4 weeks III. Epidemiology Foodbourne (...) es (30-40% of episodes) (90% of non- l diarhea) and s (20-30% of episodes) Inflammatory Diarrhea from and s (most common ) Shiga-toxin producing (e.g. :H7, ) Causes 30% of infectious bloody Diarrhea Non-inflammatory Diarrhea from and s Bacillus cereus VII. Risk Factors See for systemic medical condition causes of Diarrhea See Recent travel to endemic area See Travel to a developing area is associated with a 25% chance of developing Diarrhea Those with Diarrhea in a developing area have an 80

2015 FP Notebook

151. Antibiotic Associated Diarrhea

Diarrhea Antibiotic Associated Diarrhea Aka: Antibiotic Associated Diarrhea , Diarrhea Secondary to Antibiotic Use , Antibiotic-Associated Diarrhea From Related Chapters II. Precautions Antibiotics in the emergency department frequently cause IV antibiotics: 26% of cases Oral antibiotics: 12% of cases , and antibiotic combinations were highest risk for Reconsider whether antibiotics are indicated and if so, if IV route is needed Oral bioavailability of most antibiotics is excellent Single dose IV (...) antibiotics prior to home oral antibiotics is rarely indicated References Arora and Menchine in Herbert (2015) EM:Rap 15(1): 11 III. Causes: Bacterial Overgrowth Syndromes secondary to antibiotics oxytoca Responds to stopping antibiotics (and possibly to stopping s) IV. Prevention: Probiotics Efficacy (NNT): 13 Treating 13 patients prevents one case of Antibiotic Associated Diarrhea Live-culture yogurt reduces due to antibiotics Lactobacillus acidophilus Lactobacillus bulgaricus thermophilus Other

2015 FP Notebook

152. Safety Study of Recombinant Vaccine to Prevent ETEC Diarrhea

to Prevent ETEC Diarrhea The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01382095 Recruitment Status : Completed First Posted : June 27, 2011 Last Update Posted : April 27, 2015 Sponsor: U.S. Army Medical Research and Materiel Command Information provided by (Responsible Party): U.S. Army Medical Research (...) Reed Army Institute of Research ) First Posted: June 27, 2011 Last Update Posted: April 27, 2015 Last Verified: April 2015 Keywords provided by U.S. Army Medical Research and Materiel Command: ETEC Diarrhea Vaccine Additional relevant MeSH terms: Layout table for MeSH terms Escherichia coli Infections Enterobacteriaceae Infections Gram-Negative Bacterial Infections Bacterial Infections

2011 Clinical Trials

153. Efficacy of Mesalamine in Diarrhea-predominant Irritable Bowel Syndrome (dIBS)

Patients who drink over 2oz alcohol/day on a regular basis Any other causes for diarrhea such as IBD, microscopic colitis, celiac disease, history of abdominal obstruction, pancreatitis, ileus, or any gastrointestinal bleeding. Patients with active malignancy in the past five years Patient with any history of hypersensitivity reactions to salicylate containing medications due to cross-sensitivity with mesalamine or allergy to mesalamine medications in the past Any subjects with fibromyalgia (...) Efficacy of Mesalamine in Diarrhea-predominant Irritable Bowel Syndrome (dIBS) Efficacy of Mesalamine in Diarrhea-predominant Irritable Bowel Syndrome (dIBS) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2011 Clinical Trials

154. Bioequivalence Between a Racecadotril Capsule and Film-Coated Tablet (FCT) to Treat Diarrhea in Adults

Bioequivalence Between a Racecadotril Capsule and Film-Coated Tablet (FCT) to Treat Diarrhea in Adults Bioequivalence Between a Racecadotril Capsule and Film-Coated Tablet (FCT) to Treat Diarrhea in Adults - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Bioequivalence Between a Racecadotril Capsule and Film-Coated Tablet (FCT) to Treat Diarrhea in Adults The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01302093 Recruitment Status : Completed First Posted : February 23, 2011 Last Update Posted : July 10

2011 Clinical Trials

155. Zinc Supplementation and Severe and Recurrent Diarrhea

Diarrhea The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01306097 Recruitment Status : Completed First Posted : March 1, 2011 Last Update Posted : March 1, 2011 Sponsor: Hormozgan University of Medical Sciences Information provided by: Hormozgan University of Medical Sciences Study Details Study (...) : 1 years ] Incidence, Duration and frequency Secondary Outcome Measures : Admission for diarrhea [ Time Frame: 1 year ] Total number of admissions during the study period Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using

2011 Clinical Trials

156. Early Administration of Lactose-free Milk in Children Presenting With Acute Diarrhea

adding more. Early Administration of Lactose-free Milk in Children Presenting With Acute Diarrhea The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01269892 Recruitment Status : Completed First Posted : January 4, 2011 Last Update Posted : January 4, 2011 Sponsor: Isfahan University of Medical Sciences (...) Information provided by: Isfahan University of Medical Sciences Study Details Study Description Go to Brief Summary: The purpose of this study is to determine which nutritional regime is better for acute diarrhea in outcomes. Condition or disease Intervention/treatment Phase Acute Diarrhea Dietary Supplement: lactose-free milk Dietary Supplement: conventional milk Phase 2 Detailed Description: Diarrhea is still the most important cause of mortality and morbidity in children of the developing countries. We

2011 Clinical Trials

157. Effect of Herbal Extract Granules Combined With Probiotics on Irritable Bowel Syndrome With Diarrhea

Sponsor: Kyunghee University Medical Center Information provided by (Responsible Party): Seok-Jae Ko, Kyunghee University Medical Center Study Details Study Description Go to Brief Summary: The aims of this study are to investigate the effect of famous herbal formula extract and probiotics on irritable bowel syndrome with diarrhea, and to determine whether these two experimental items affect intestinal permeability and the composition of intestinal microbiota. Condition or disease Intervention (...) : June 5, 2012 Last Verified: June 2012 Keywords provided by Seok-Jae Ko, Kyunghee University Medical Center: Irritable bowel syndrome Herbal medicine Probiotics Additional relevant MeSH terms: Layout table for MeSH terms Syndrome Diarrhea Irritable Bowel Syndrome Disease Pathologic Processes Signs and Symptoms, Digestive Signs and Symptoms Colonic Diseases, Functional Colonic Diseases Intestinal Diseases Gastrointestinal Diseases Digestive System Diseases

2011 Clinical Trials

158. Prevention of Irinotecan Induced Diarrhea by Probiotics

cycles the starting dose is 3x1 cps per day, or the dose according to dose adjustments from the previous treatment cycle. Outcome Measures Go to Primary Outcome Measures : Prevention of grade 3-4 diarrhea by probiotics in patients treated by irinotecan based chemotherapy [ Time Frame: 2 years ] Secondary Outcome Measures : Prevention of any grade of diarrhea [ Time Frame: 2 years ] Number of patients with any grade 3 or 4 toxicity or SAE related toxicity. [ Time Frame: 2 years ] Number of patients (...) Prevention of Irinotecan Induced Diarrhea by Probiotics Prevention of Irinotecan Induced Diarrhea by Probiotics - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Prevention of Irinotecan Induced Diarrhea

2011 Clinical Trials

159. Probiotic Lactobacillus Reuteri to Prevent Antibiotic-associated Diarrhea and Clostridium Difficile-related Infections in Hospitalized Children

in patients ingesting L. reuteri versus placebo during the study period, measured as mean number of episodes per patient. An episode of diarrhea is defined as three or more (≥ 3) soft and unformed or watery bowel movements per day for at least 48 hours. Secondary Outcome Measures : Incidence of mild diarrhea and severity if diarrhea in children with probiotic treatment [ Time Frame: 2 years ] Incidence of mild diarrhoea during and after treatment with antibiotics in patients ingesting L. reuteri versus (...) Probiotic Lactobacillus Reuteri to Prevent Antibiotic-associated Diarrhea and Clostridium Difficile-related Infections in Hospitalized Children Probiotic Lactobacillus Reuteri to Prevent Antibiotic-associated Diarrhea and Clostridium Difficile-related Infections in Hospitalized Children - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save

2011 Clinical Trials

160. Cost-effectiveness of Infloran (TM) in Treating Acute Childhood Diarrhea in Phramongkutklao Hospital

Cost-effectiveness of Infloran (TM) in Treating Acute Childhood Diarrhea in Phramongkutklao Hospital Cost-effectiveness of Infloran (TM) in Treating Acute Childhood Diarrhea in Phramongkutklao Hospital - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Cost-effectiveness of Infloran (TM) in Treating Acute Childhood Diarrhea in Phramongkutklao Hospital (infloran) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01273012 Recruitment Status : Unknown Verified July 2011 by Phramongkutklao College of Medicine

2011 Clinical Trials

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